Western Blot: Shwachman Bodian-Diamond syndrome Antibody (1E8) [NBP2-22594] - Lane 1. 293T cell lysate, Lane 2. HeLa cell lysate.
Immunocytochemistry/ Immunofluorescence: Shwachman Bodian-Diamond syndrome Antibody (1E8) [NBP2-22594] - Analysis in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human SBDS antibody ...read more
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified
Alternate Names for Ribosome maturation protein SBDS Antibody (1E8) - BSA Free
FLJ10917
ribosome maturation protein SBDS
SDSCGI-97
Shwachman-Bodian-Diamond syndrome protein
Shwachman-Bodian-Diamond syndrome
SWDS
Background
The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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