| Liu, Y;Yin, M;Mao, X;Wu, S;Wei, S;Heng, S;Yang, Y;Huang, J;Guo, Z;Li, C;Ji, C;Hu, L;Liu, W;Zhang, LJ; Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics eLife 2024-08-30 [PMID: 39213029] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Singh, SS;Calvo, R;Kumari, A;Sable, RV;Fang, Y;Tao, D;Hu, X;Castle, SG;Nahar, S;Li, D;Major, E;Sanchez, TW;Kato, R;Xu, X;Zhou, J;Liu, L;LeClair, CA;Simeonov, A;Baljinnyam, B;Henderson, MJ;Marugan, J;Rudloff, U; Fatty acid derivatization and cyclization of the immunomodulatory peptide RP-182 targeting CD206high macrophages improves anti-tumor activity Molecular cancer therapeutics 2024-08-30 [PMID: 39212669] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wallings, RL;Gillett, DA;Staley, HA;Mahn, S;Mark, J;Neighbarger, N;Kordasiewicz, H;Hirst, WD;Tansey, MG; ASO-mediated knockdown of GPNMB in mutant- GRN and Grn -deficient peripheral myeloid cells disrupts lysosomal function and immune responses bioRxiv : the preprint server for biology 2024-07-23 [PMID: 39211224] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Malone, K;Dugas, M;Earl, N;Alain, T;LaCasse, EC;Beug, ST; Astrocytes and the tumor microenvironment inflammatory state dictate the killing of glioblastoma cells by Smac mimetic compounds Cell death & disease 2024-08-15 [PMID: 39147758] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Barrero, M;Lazarenkov, A;Blanco, E;Palma, LG;López-Rubio, AV;Bauer, M;Bigas, A;Di Croce, L;Sardina, JL;Payer, B; The interferon ? pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming Science advances 2024-08-09 [PMID: 39110794] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Marrufo, AM;Molina, JJ;Gager, C;Andersen, MJ;LaBella, AA;Lucas, ER;Wongso, E;Urmi, T;Arias-Parbul, K;Webster, R;Stuckey, PV;Kohler, KN;Donahue, D;Ploplis, VA;Flick, MJ;Castellino, FJ;Santiago-Tirado, FH;Flores-Mireles, AL; The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI bioRxiv : the preprint server for biology 2024-07-17 [PMID: 39071295] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wofford, W;Kim, J;Kim, D;Janneh, AH;Lee, HG;Atilgan, FC;Oleinik, N;Kassir, MF;Saatci, O;Chakraborty, P;Tokat, UM;Gencer, S;Howley, B;Howe, P;Mehrotra, S;Sahin, O;Ogretmen, B; Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response Cell reports 2024-07-23 [PMID: 39046874] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
| Li, C;Wang, B;Tu, J;Liu, C;Wang, Y;Chen, J;Huang, Y;Liu, B;Yuan, X; ATM inhibition enhance immunotherapy by activating STING signaling and augmenting MHC Class I Cell death & disease 2024-07-20 [PMID: 39033176] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Dutta, B;Mahanty, M;Kesavalu, L;Rahaman, SO; Mechanisms underlying TRPV4-mediated regulation of miR-146a expression bioRxiv : the preprint server for biology 2024-04-03 [PMID: 38617263] (Bioassay, Mouse, Transgenic Mouse) |
Bioassay |
Mouse, Transgenic Mouse |
| Pitter, MR;Kryczek, I;Zhang, H;Nagarsheth, N;Xia, H;Wu, Z;Tian, Y;Okla, K;Liao, P;Wang, W;Zhou, J;Li, G;Lin, H;Vatan, L;Grove, S;Wei, S;Li, Y;Zou, W; PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages Cell reports 2024-03-13 [PMID: 38489266] (Bioassay, Human) |
Bioassay |
Human |
| Sorenson, CM;Gurel, Z;Song, YS;Peterson, KD;Blodi, BA;Sheibani, N; Thrombospondin-1, BIM and CFH polymorphisms and response to anti-VEGF treatment in neovascular age- related macular degeneration patients PloS one 2024-02-26 [PMID: 38408093] (Bioassay, Mouse, Transgenic Mouse) |
Bioassay |
Mouse, Transgenic Mouse |
| Sun, R;Lei, C;Xu, Z;Gu, X;Huang, L;Chen, L;Tan, Y;Peng, M;Yaddanapudi, K;Siskind, L;Kong, M;Mitchell, R;Yan, J;Deng, Z; Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages Nature communications 2024-02-01 [PMID: 38302493] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Li, T;Bao, Y;Xia, Y;Meng, H;Zhou, C;Huang, L;Wang, X;Lai, EY;Jiang, P;Mao, J; Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients International journal of biological sciences 2024-01-12 [PMID: 38250156] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Hou, Y;Wei, D;Zhang, Z;Lei, T;Li, S;Bao, J;Guo, H;Tan, L;Xie, X;Zhuang, Y;Lu, Z;Zhao, Y; Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes Cell reports 2024-01-03 [PMID: 38175755] (Bioassay, Mouse, Transgenic Mouse) |
Bioassay |
Mouse, Transgenic Mouse |
| Lin, YL;Cheng, PY;Chin, CL;Chuang, KT;Lin, JY;Chang, N;Pan, CK;Lin, CS;Pan, SC;Chiang, BL; A novel mucosal bivalent vaccine of EV-A71/EV-D68 adjuvanted with polysaccharides from Ganoderma lucidum protects mice against EV-A71 and EV-D68 lethal challenge Journal of biomedical science 2023-12-18 [PMID: 38110940] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Hilligan, KL;Namasivayam, S;Clancy, CS;Baker, PJ;Old, SI;Peluf, V;Amaral, EP;Oland, SD;O'Mard, D;Laux, J;Cohen, M;Garza, NL;Lafont, BAP;Johnson, RF;Feng, CG;Jankovic, D;Lamiable, O;Mayer-Barber, KD;Sher, A; Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2 Nature communications 2023-12-12 [PMID: 38086794] (In vivo assay, Mouse) |
In vivo assay |
Mouse |
| Pan, ML;Ahmad Puzi, NN;Ooi, YY;Ramasamy, R;Vidyadaran, S; Response Profiles of BV2 Microglia to IFN-? and LPS Co-Stimulation and Priming Biomedicines 2023-09-27 [PMID: 37893022] (Bioassay, Mouse) |
Bioassay |
Mouse |
| |
|
|
| Bao, Y;Qiao, Y;Choi, JE;Zhang, Y;Mannan, R;Cheng, C;He, T;Zheng, Y;Yu, J;Gondal, M;Cruz, G;Grove, S;Cao, X;Su, F;Wang, R;Chang, Y;Kryczek, I;Cieslik, M;Green, MD;Zou, W;Chinnaiyan, AM; Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy Proceedings of the National Academy of Sciences of the United States of America 2023-12-05 [PMID: 38011559] (ICC, Xenograft) |
ICC |
Xenograft |
| Chuang, WH;Pislyagin, E;Lin, LY;Menchinskaya, E;Chernikov, O;Kozhemyako, V;Gorpenchenko, T;Manzhulo, I;Chaikina, E;Agafonova, I;Silchenko, A;Avilov, S;Stonik, V;Tzou, SC;Aminin, D;Wang, YM; Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy Cancer cell international 2023-11-24 [PMID: 38001420] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Merchak, AR;Wachamo, S;Brown, LC;Thakur, A;Moreau, B;Brown, RM;Rivet-Noor, C;Raghavan, T;Gaultier, A; Lactobacillus from the Altered Schaedler Flora maintain IFN? homeostasis to promote behavioral stress resilience Brain, behavior, and immunity 2023-11-02 [PMID: 37924959] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Wu, L;Yin, W;Wen, J;Wang, S;Li, H;Wang, X;Zhang, W;Duan, S;Zhu, Q;Gao, E;Wu, S;Zhan, B;Zhou, R;Yang, X; Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model Parasites & vectors 2023-10-16 [PMID: 37845695] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Adrian, M;Weber, M;Tsai, MC;Glock, C;Kahn, OI;Phu, L;Cheung, TK;Meilandt, WJ;Rose, CM;Hoogenraad, CC; Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release Nature communications 2023-10-09 [PMID: 37813836] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Baumgartner, CK;Ebrahimi-Nik, H;Iracheta-Vellve, A;Hamel, KM;Olander, KE;Davis, TGR;McGuire, KA;Halvorsen, GT;Avila, OI;Patel, CH;Kim, SY;Kammula, AV;Muscato, AJ;Halliwill, K;Geda, P;Klinge, KL;Xiong, Z;Duggan, R;Mu, L;Yeary, MD;Patti, JC;Balon, TM;Mathew, R;Backus, C;Kennedy, DE;Chen, A;Longenecker, K;Klahn, JT;Hrusch, CL;Krishnan, N;Hutchins, CW;Dunning, JP;Bulic, M;Tiwari, P;Colvin, KJ;Chuong, CL;Kohnle, IC;Rees, MG;Boghossian, A;Ronan, M;Roth, JA;Wu, MJ;Suermondt, JSMT;Knudsen, NH;Cheruiyot, CK;Sen, DR;Griffin, GK;Golub, TR;El-Bardeesy, N;Decker, JH;Yang, Y;Guffroy, M;Fossey, S;Trusk, P;Sun, IM;Liu, Y;Qiu, W;Sun, Q;Paddock, MN;Farney, EP;Matulenko, MA;Beauregard, C;Frost, JM;Yates, KB;Kym, PR;Manguso, RT; The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity Nature 2023-10-04 [PMID: 37794185] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Li, H;Wang, Y;Yang, F;Feng, S;Chang, K;Yu, X;Guan, F;Li, X; Clonal MDS/AML cells with enhanced TWIST1 expression reprogram the differentiation of bone marrow MSCs Redox biology 2023-09-21 [PMID: 37748319] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Aboushousha, R;van der Velden, J;Hamilton, N;Peng, Z;MacPherson, M;Erickson, C;White, S;Wouters, EFM;Reynaert, NL;Seward, DJ;Li, J;Janssen-Heininger, YMW; Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system xC Science advances 2023-09-15 [PMID: 37703360] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Arp, NL;Seim, G;Josephson, J;Fan, J; Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism bioRxiv : the preprint server for biology 2023-07-31 [PMID: 37577551] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ono, K;Sato, J;Suzuki, H;Sawada, M; Distribution of Signal Peptides in Microvesicles from Activated Macrophage Cells International journal of molecular sciences 2023-07-28 [PMID: 37569508] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wang, Y;Wu, T;Tsai, MC;Rezzonico, MG;Abdel-Haleem, AM;Xie, L;Gandham, VD;Ngu, H;Stark, K;Glock, C;Xu, D;Foreman, O;Friedman, BA;Sheng, M;Hanson, JE; TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice eLife 2023-08-09 [PMID: 37555828] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Castiglioni, A;Yang, Y;Williams, K;Gogineni, A;Lane, RS;Wang, AW;Shyer, JA;Zhang, Z;Mittman, S;Gutierrez, A;Astarita, JL;Thai, M;Hung, J;Yang, YA;Pourmohamad, T;Himmels, P;De Simone, M;Elstrott, J;Capietto, AH;Cubas, R;Modrusan, Z;Sandoval, W;Ziai, J;Gould, SE;Fu, W;Wang, Y;Koerber, JT;Sanjabi, S;Mellman, I;Turley, SJ;Müller, S; Combined PD-L1/TGF? blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors Nature communications 2023-08-05 [PMID: 37543621] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Rachdi, L;Zhou, Z;Berthault, C;Lourenço, C;Fouque, A;Domet, T;Armanet, M;You, S;Peakman, M;Mallone, R;Scharfmann, R; Tryptophan metabolism promotes immune evasion in human pancreatic beta cells EBioMedicine 2023-08-01 [PMID: 37536063] (Bioassay, Human) |
Bioassay |
Human |
| Olabiyi, BF;Schmoele, AC;Beins, EC;Zimmer, A; Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-gamma -induced microglial activation Scientific reports 2023-07-10 [PMID: 37429837] (Stimulation, Mouse) |
Stimulation |
Mouse |
| Bod, L;Kye, YC;Shi, J;Torlai Triglia, E;Schnell, A;Fessler, J;Ostrowski, SM;Von-Franque, MY;Kuchroo, JR;Barilla, RM;Zaghouani, S;Christian, E;Delorey, TM;Mohib, K;Xiao, S;Slingerland, N;Giuliano, CJ;Ashenberg, O;Li, Z;Rothstein, DM;Fisher, DE;Rozenblatt-Rosen, O;Sharpe, AH;Quintana, FJ;Apetoh, L;Regev, A;Kuchroo, VK; B-cell-specific checkpoint molecules that regulate anti-tumour immunity Nature 2023-06-21 [PMID: 37344597] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| Zhai, R;Lenga Ma Bonda, W;Leclaire, C;Saint-Béat, C;Theilliere, C;Belville, C;Coupet, R;Blondonnet, R;Bouvier, D;Blanchon, L;Sapin, V;Jabaudon, M; Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome Journal of translational medicine 2023-06-18 [PMID: 37331963] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Baars, I;Jaedtka, M;Dewitz, LA;Fu, Y;Franz, T;Mohr, J;Gintschel, P;Berlin, H;Degen, A;Freier, S;Rygol, SM;Schraven, B;Kahlfuss, S;van Zandbergen, G;Müller, AJ; Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate JCI insight 2023-06-13 [PMID: 37310793] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Waugh, KA;Minter, R;Baxter, J;Chi, C;Galbraith, MD;Tuttle, KD;Eduthan, NP;Kinning, KT;Andrysik, Z;Araya, P;Dougherty, H;Dunn, LN;Ludwig, M;Schade, KA;Tracy, D;Smith, KP;Granrath, RE;Busquet, N;Khanal, S;Anderson, RD;Cox, LL;Estrada, BE;Rachubinski, AL;Lyford, HR;Britton, EC;Fantauzzo, KA;Orlicky, DJ;Matsuda, JL;Song, K;Cox, TC;Sullivan, KD;Espinosa, JM; Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model Nature genetics 2023-06-05 [PMID: 37277650] (Bioassay, Transgenic Mouse) |
Bioassay |
Transgenic Mouse |
| Nohara, LL;Ellis, SLS;Dreier, C;Dada, S;Saranchova, I;Munro, L;Pfeifer, CG;Coyle, KM;Morrice, JR;Shim, DJS;Ahn, P;De Voogd, N;Williams, DE;Cheng, P;Garrovillas, E;Andersen, RJ;Jefferies, WA; A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours Frontiers in pharmacology 2023-05-15 [PMID: 37256225] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wayne, CR;Bremner, L;Faust, TE;Dur�n-Laforet, V;Ampatey, N;Ho, SJ;Feinberg, PA;Arvanitis, P;Ciric, B;Ruan, C;Elyaman, W;Delaney, SL;Vargas, WS;Swedo, S;Menon, V;Schafer, DP;Cutforth, T;Agalliu, D; Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis bioRxiv : the preprint server for biology 2023-05-09 [PMID: 37215000] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Naito, Y;Koyama, S;Masuhiro, K;Hirai, T;Uenami, T;Inoue, T;Osa, A;Machiyama, H;Watanabe, G;Sax, N;Villa, J;Kinugasa-Katayama, Y;Nojima, S;Yaga, M;Hosono, Y;Okuzaki, D;Satoh, S;Tsuda, T;Nakanishi, Y;Suga, Y;Morita, T;Fukushima, K;Nishide, M;Shiroyama, T;Miyake, K;Iwahori, K;Hirata, H;Nagatomo, I;Yano, Y;Tamiya, M;Kumagai, T;Takemoto, N;Inohara, H;Yamasaki, S;Yamashita, K;Aoshi, T;Akbay, EA;Hosen, N;Shintani, Y;Takamatsu, H;Mori, M;Takeda, Y;Kumanogoh, A; Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation Science advances 2023-05-19 [PMID: 37205755] (Bioassay, Transgenic Mouse, Mouse) |
Bioassay |
Transgenic Mouse, Mouse |
| Slieker, RC;Donnelly, LA;Akalestou, E;Lopez-Noriega, L;Melhem, R;G�ne?, A;Abou Azar, F;Efanov, A;Georgiadou, E;Muniangi-Muhitu, H;Sheikh, M;Giordano, GN;�kerlund, M;Ahlqvist, E;Ali, A;Banasik, K;Brunak, S;Barovic, M;Bouland, GA;Burdet, F;Canouil, M;Dragan, I;Elders, PJM;Fernandez, C;Festa, A;Fitipaldi, H;Froguel, P;Gudmundsdottir, V;Gudnason, V;Gerl, MJ;van der Heijden, AA;Jennings, LL;Hansen, MK;Kim, M;Leclerc, I;Klose, C;Kuznetsov, D;Mansour Aly, D;Mehl, F;Marek, D;Melander, O;Niknejad, A;Ottosson, F;Pavo, I;Duffin, K;Syed, SK;Shaw, JL;Cabrera, O;Pullen, TJ;Simons, K;Solimena, M;Suvitaival, T;Wretlind, A;Rossing, P;Lyssenko, V;Legido Quigley, C;Groop, L;Thorens, B;Franks, PW;Lim, GE;Estall, J;Ibberson, M;Beulens, JWJ;'t Hart, LM;Pearson, ER;Rutter, GA; Identification of biomarkers for glycaemic deterioration in type 2 diabetes Nature communications 2023-05-03 [PMID: 37137910] (Bioassay, Mouse) |
Bioassay |
Mouse |
| BD Hobson, AT Stanley, MB De Los San, B Culbertson, EV Mosharov, PA Sims, D Sulzer Conserved and cell type-specific transcriptional responses to IFN-gamma in the ventral midbrain Brain, Behavior, and Immunity, 2023-04-24;0(0):. 2023-04-24 [PMID: 37100211] (Bioassay, Mouse) |
Bioassay |
Mouse |
| V Göser, N Sander, M Schulte, F Scharte, R Franzkoch, V Liss, OE Psathaki, M Hensel Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes Nature Communications, 2023-03-04;14(1):1240. 2023-03-04 [PMID: 36870997] (Bioassay, Mouse) |
Bioassay |
Mouse |
| V Göser, N Sander, M Schulte, F Scharte, R Franzkoch, V Liss, OE Psathaki, M Hensel Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes Nature Communications, 2023;14(1):1240. 2023 [PMID: 36870997] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Liao, L Sun, M Nie, J Li, X Huang, S Heng, W Zhang, T Xia, Z Guo, Q Zhao, LJ Zhang Modulation of Skin Inflammatory Responses by Aluminum Adjuvant Pharmaceutics, 2023-02-08;15(2):. 2023-02-08 [PMID: 36839900] (Mouse) |
|
Mouse |
| CY Hsieh, JN Lin, TY Kang, YH Wen, SH Yu, CC Wu, HP Wu Otoprotective Effects of Fucoidan Reduce Cisplatin-Induced Ototoxicity in Mouse Cochlear UB/OC-2 Cells International Journal of Molecular Sciences, 2023-02-10;24(4):. 2023-02-10 [PMID: 36834972] (Bioassay, Mouse) |
Bioassay |
Mouse |
| EG Foerster, DKL Tsang, S Goyal, SJ Robertson, LM Robert, H Maughan, CJ Streutker, SE Girardin, DJ Philpott ATG16L1 protects from interferon-gamma-induced cell death in the small intestinal crypt Mucosal Immunology, 2023-02-14;0(0):. 2023-02-14 [PMID: 36792009] (Bioassay, Transgenic Mouse) |
Bioassay |
Transgenic Mouse |
| WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway International Journal of Molecular Sciences, 2023;24(3):. 2023 [PMID: 36768873] (Bioassay, Mouse) |
Bioassay |
Mouse |
| WH Lee, GE Kim, KJ Hong, HS Kim, GR Lee Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway International Journal of Molecular Sciences, 2023-01-29;24(3):. 2023-01-29 [PMID: 36768873] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Yu, Y Shen, J Luo, J Jin, P Li, P Feng, H Guan Upadacitinib inhibits corneal inflammation and neovascularization by suppressing M1 macrophage infiltration in the corneal alkali burn model International immunopharmacology, 2023-02-03;116(0):109680. 2023-02-03 [PMID: 36739832] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Li, N Liu, H Zhou, P Xian, Y Song, X Tang, Y Li, M Basler Immunoproteasome inhibition prevents progression of castration-resistant prostate cancer British Journal of Cancer, 2023-01-21;0(0):. 2023-01-21 [PMID: 36681728] (Bioassay, Mouse) |
Bioassay |
Mouse |
| L Tang, M Zhu, X Che, X Yang, Y Xu, Q Ma, M Zhang, Z Ni, X Shao, S Mou Astragaloside IV Targets Macrophages to Alleviate Renal Ischemia-Reperfusion Injury via the Crosstalk between Hif-1alpha and NF-kappaB (p65)/Smad7 Pathways Journal of personalized medicine, 2022-12-27;13(1):. 2022-12-27 [PMID: 36675720] (Bioassay, Mouse) |
Bioassay |
Mouse |
| G Spiaggia, P Taladriz-B, S Hengsberge, D Septiadi, C Geers, A Lee, B Rothen-Rut, A Petri-Fink A Near-Infrared Mechanically Switchable Elastomeric Film as a Dynamic Cell Culture Substrate Biomedicines, 2022-12-22;11(1):. 2022-12-22 [PMID: 36672538] (ELISA Control, Mouse) |
ELISA Control |
Mouse |
| YS Song, N Jamali, CM Sorenson, N Sheibani Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells Cells, 2023-01-16;12(2):. 2023-01-16 [PMID: 36672270] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M De Burghgr, C Lourenço, C Berthault, V Aiello, A Villalba, A Fouque, M Diedisheim, S You, M Oshima, R Scharfmann Pancreatic Islet Cells Response to IFNgamma Relies on Their Spatial Location within an Islet Cells, 2022-12-28;12(1):. 2022-12-28 [PMID: 36611907] (Bioassay, Mouse) |
Bioassay |
Mouse |
| X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, M Dougan, L Su, X Zhao, J Piehler, KC Garcia Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy Nature Biotechnology, 2023;0(0):. 2023 [PMID: 36593402] (Bioassay, Mouse) |
Bioassay |
Mouse |
| X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, M Dougan, L Su, X Zhao, J Piehler, KC Garcia Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy Nature Biotechnology, 2023-01-02;0(0):. 2023-01-02 [PMID: 36593402] (Bioassay, Mouse) |
Bioassay |
Mouse |
| YK Kim, JA Walters, ND Moss, KL Wells, R Sheridan, JG Miranda, RKP Benninger, LL Pyle, RM O'Brien, L Sussel, HW Davidson Zinc Transporter 8 Haploinsufficiency Protects Against Beta Cell Dysfunction in Type 1 Diabetes by Increasing Mitochondrial Respiration Molecular Metabolism, 2022-11-05;66(0):101632. 2022-11-05 [PMID: 36347424] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Wang, Z Huang, Y Peng, H Li, T Lin, Y Zhao, Z Hu, Z Zhou, W Zhou, Y Liu, FF Hou Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair Nature Communications, 2022-10-31;13(1):6502. 2022-10-31 [PMID: 36316334] (Bioassay, Mouse) |
Bioassay |
Mouse |
| KK Myo Min, D Rojas-Cana, D Penko, M DeNichilo, MP Cockshell, CB Ffrench, EJ Thompson, O Asplund, CJ Drogemulle, RB Prasad, L Groop, ST Grey, HE Thomas, T Loudovaris, TW Kay, MG Mahoney, CF Jessup, PT Coates, CS Bonder Desmoglein-2 is important for islet function and beta-cell survival Cell Death & Disease, 2022-10-29;13(10):911. 2022-10-29 [PMID: 36309486] (Bioassay, Mouse) |
Bioassay |
Mouse |
| F Babaeijand, A Paiero, R Long, LW Tung, SP Smith, R Cheng, J Smandych, N Kajabadi, CK Chang, A Ghassemi, WDM Kennedy, H Soliman, PW Schutz, FMV Rossi TNFalpha and IFNgamma cooperate for efficient pro- to anti-inflammatory transition of macrophages during muscle regeneration Proceedings of the National Academy of Sciences of the United States of America, 2022-10-24;119(44):e2209976119. 2022-10-24 [PMID: 36279473] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AP Shaik, AS Shaik, M Abudawood, A Al Faraj Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses BioMed Research International, 2022-10-06;2022(0):9470845. 2022-10-06 [PMID: 36246991] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Cho, HY Kwon, A Sharma, SH Lee, X Liu, N Miyamoto, JJ Kim, SH Im, NY Kang, YT Chang Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target Nature Communications, 2022-10-10;13(1):5974. 2022-10-10 [PMID: 36216803] (Bioassay, Mouse) |
Bioassay |
Mouse |
| N Zoellner, N Coesfeld, FH De Vos, J Denter, HC Xu, E Zimmer, B Knebel, H Al-Hasani, S Mossner, PA Lang, DM Floss, J Scheller Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling Frontiers in Microbiology, 2022-09-02;13(0):947169. 2022-09-02 [PMID: 36118237] (Bioassay, Mouse) |
Bioassay |
Mouse |
| KA Meerschaer, BS Edwards, AY Epouhe, B Jefferson, R Friedman, OL Babyok, JK Moy, F Kehinde, C Liu, CJ Workman, DAA Vignali, KM Albers, HR Koerber, MS Gold, BM Davis, NN Scheff, JL Saloman Neuronally expressed PDL1, not PD1, suppresses acute nociception Brain, Behavior, and Immunity, 2022-09-08;106(0):233-246. 2022-09-08 [PMID: 36089217] (Bioassay, Mouse) |
Bioassay |
Mouse |
| I Mhatre-Win, A Eid, Y Han, K Tieu, JR Richardson Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice International Journal of Molecular Sciences, 2022-08-29;23(17):. 2022-08-29 [PMID: 36077227] (Bioassay, Mouse) |
Bioassay |
Mouse |
| T Otsuki, N Fukuda, L Chen, A Tsunemi, M Abe Twist-related protein 1 induces epithelial-mesenchymal transition and renal fibrosis through the upregulation of complement 3 PLoS ONE, 2022-08-26;17(8):e0272917. 2022-08-26 [PMID: 36018840] (Bioassay, Mouse) |
Bioassay |
Mouse |
| T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119. 2022-08-22 [PMID: 35994674] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge STUB1 is an intracellular checkpoint for interferon gamma sensing Scientific Reports, 2022-08-18;12(1):14087. 2022-08-18 [PMID: 35982220] (Bioassay, Human) |
Bioassay |
Human |
| S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii Nature Communications, 2022-08-08;13(1):4605. 2022-08-08 [PMID: 35941154] (Bioassay, Mouse) |
Bioassay |
Mouse |
| EG Vasquez, N Nasreddin, GN Valbuena, EJ Mulholland, HL Belnoue-Da, HR Eggington, RO Schenck, VM Wouters, P Wirapati, K Gilroy, TRM Lannagan, DJ Flanagan, AK Najumudeen, S Omwenga, AMB McCorry, A Easton, VH Koelzer, JE East, D Morton, L Trusolino, T Maughan, AD Campbell, MB Loughrey, PD Dunne, P Tsantoulis, DJ Huels, S Tejpar, OJ Sansom, SJ Leedham Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia Cell Stem Cell, 2022-08-04;29(8):1213-1228.e8. 2022-08-04 [PMID: 35931031] (Bioassay, Mouse) |
Bioassay |
Mouse |
| R Guo, X Jia, Z Ding, G Wang, M Jiang, B Li, S Chen, B Xia, Q Zhang, J Liu, R Zheng, Z Gao, X Xie Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation Theranostics, 2022-07-04;12(11):5220-5236. 2022-07-04 [PMID: 35836819] (Bioassay, Mouse) |
Bioassay |
Mouse |
| MB Bayazit, C Jacovetti, C Cosentino, J Sobel, K Wu, F Brozzi, A Rodriguez-, L Stoll, C Guay, R Regazzi Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal beta cells Cell Reports, 2022-07-12;40(2):111069. 2022-07-12 [PMID: 35830789] (Bioassay, Rat) |
Bioassay |
Rat |
| MK Ameka, WN Beavers, CM Shaver, LB Ware, VE Kerchberge, KQ Schoenfelt, L Sun, T Koyama, EP Skaar, L Becker, AH Hasty An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload International Journal of Molecular Sciences, 2022-07-03;23(13):. 2022-07-03 [PMID: 35806422] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Qu, R Heinbäck, H Salo, E Ewing, A Espinosa, C Aulin, H Erlandsson Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1 Biomolecules, 2022-06-02;12(6):. 2022-06-02 [PMID: 35740904] (Bioassay, Mouse) |
Bioassay |
Mouse |
| G Coquant, D Aguanno, L Brot, C Belloir, J Delugeard, N Roger, HP Pham, L Briand, M Moreau, L de Sordi, V Carrière, JP Grill, S Thenet, P Seksik 3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors Oncogene, 2022-06-08;12(1):9440. 2022-06-08 [PMID: 35676403] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Kamei, T Ishii, Y Nishii Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement Oncogene, 2022-06-02;12(1):9243. 2022-06-02 [PMID: 35654941] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Jin, Y Liu, L Xu, J Xu, Y Xiong, Y Peng, K Ding, S Zheng, N Yang, Z Zhang, L Li, L Tan, H Song, J Fu Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis Cell Death & Disease, 2022-05-31;13(5):512. 2022-05-31 [PMID: 35641492] (Bioassay, Mouse) |
Bioassay |
Mouse |
| R Mary, F Chalmin, T Accogli, M Bruchard, C Hibos, J Melin, C Truntzer, E Limagne, V Derangère, M Thibaudin, E Humblin, R Boidot, S Chevrier, L Arnould, C Richard, Q Klopfenste, A Bernard, Y Urade, JA Harker, L Apetoh, F Ghiringhel, F Végran Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects Cancer Immunology Research, 2022-07-01;0(0):OF1-OF17. 2022-07-01 [PMID: 35612500] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SO Vasudevan, AJ Russo, P Kumari, SK Vanaja, VA Rathinam A TLR4-independent critical role for CD14 in intracellular LPS sensing Cell Reports, 2022-05-03;39(5):110755. 2022-05-03 [PMID: 35508125] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Steiner, K Hrovat-Sch, I Prigione, CH Yu, P Laohamonth, CR Harapas, RRJ Low, D De Nardo, LF Dagley, MJ Mlodzianos, KL Rogers, T Zillinger, G Hartmann, MP Gantier, M Gattorno, M Geyer, S Volpi, S Davidson, SL Masters Deficiency in coatomer complex I causes aberrant activation of STING signalling Nature Communications, 2022-04-28;13(1):2321. 2022-04-28 [PMID: 35484149] (Bioassay, Human) |
Bioassay |
Human |
| W Piao, L Li, V Saxena, J Iyyathurai, R Lakhan, Y Zhang, IT Lape, C Paluskievi, KL Hippen, Y Lee, E Silverman, MW Shirkey, LV Riella, BR Blazar, JS Bromberg PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration Nature Communications, 2022-04-21;13(1):2176. 2022-04-21 [PMID: 35449134] (Bioassay, Mouse) |
Bioassay |
Mouse |
| ML Yang, S Horstman, R Gee, P Guyer, TT Lam, J Kanyo, AL Perdigoto, C Speake, CJ Greenbaum, A Callebaut, L Overbergh, RG Kibbey, KC Herold, EA James, MJ Mamula Citrullination of glucokinase is linked to autoimmune diabetes Nature Communications, 2022-04-06;13(1):1870. 2022-04-06 [PMID: 35388005] (Bioassay, Rat) |
Bioassay |
Rat |
| L Liu, RM Lucas, JD Nanson, Y Li, J Whitfield, JEB Curson, N Tuladhar, K Alexandrov, M Mobli, MJ Sweet, B Kobe, J Stow, L Luo The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs The Journal of Biological Chemistry, 2022-03-22;0(0):101857. 2022-03-22 [PMID: 35337798] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Stancic, T Saksida, M Markelic, M Vucetic, I Grigorov, V Martinovic, D Gajic, A Ivanovic, K Velickovic, N Savic, V Otasevic Ferroptosis as a Novel Determinant of beta-Cell Death in Diabetic Conditions Oxidative Medicine and Cellular Longevity, 2022-03-14;2022(0):3873420. 2022-03-14 [PMID: 35320979] (Cell Culture, Rat) |
Cell Culture |
Rat |
| A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response Cancer Immunology Research, 2022-04-01;0(0):. 2022-04-01 [PMID: 35181787] (Bioassay, Human) |
Bioassay |
Human |
| SW Tuffs, MI Goncheva, SX Xu, HC Craig, KJ Kasper, J Choi, RS Flannagan, SM Kerfoot, DE Heinrichs, JK McCormick Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production Proceedings of the National Academy of Sciences of the United States of America, 2022-02-22;119(8):. 2022-02-22 [PMID: 35165181] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Jin, I Sivakumar, Y Mironchik, B Krishnamac, F Wildes, JD Barnett, CF Hung, S Nimmagadda, H Kobayashi, ZM Bhujwalla, MF Penet PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model Cancers, 2022-01-26;14(3):. 2022-01-26 [PMID: 35158887] (Bioassay, Mouse) |
Bioassay |
Mouse |
| EI Arafa, AT Shenoy, KA Barker, NS Etesami, IM Martin, C Lyon De An, E Na, CV Odom, WN Goltry, FT Korkmaz, AK Wooten, AC Belkina, A Guillon, EC Forsberg, MR Jones, LJ Quinton, JP Mizgerd Recruitment and training of alveolar macrophages after pneumococcal pneumonia JCI Insight, 2022-03-08;0(0):. 2022-03-08 [PMID: 35133985] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Z Wang, K Huang, J Xu, J Liu, Y Zheng Insights from Dysregulated mRNA Expression Profile of beta-Cells in Response to Proinflammatory Cytokines Journal of Immunology Research, 2022-01-22;2022(0):4542487. 2022-01-22 [PMID: 35103245] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JG Miranda, WE Schleicher, KL Wells, DG Ramirez, SP Landgrave, RK Benninger Dynamic changes in beta-cell [Ca2+] regulates NFAT activation, gene transcription and islet gap junction communication Oncogene, 2021-12-31;0(0):101430. 2021-12-31 [PMID: 34979329] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Mo, Q Ren, D Song, B Xu, D Zhou, X Hong, FF Hou, L Zhou, Y Liu CXCR4 induces podocyte injury and proteinuria by activating beta-catenin signaling Theranostics, 2022-01-01;12(2):767-781. 2022-01-01 [PMID: 34976212] (Bioassay, Mouse) |
Bioassay |
Mouse |
| HR McMurray, A Ambeskovic, LA Newman, J Aldersley, V Balakrishn, B Smith, HA Stern, H Land, MN McCall Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes Cell Reports, 2021-12-21;37(12):110136. 2021-12-21 [PMID: 34936873] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Chauhan, WS Sheng, S Hu, S Prasad, JR Lokensgard Differential Cytokine-Induced Responses of Polarized Microglia Brain sciences, 2021-11-10;11(11):. 2021-11-10 [PMID: 34827481] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Zhang, Y Zheng, F Shu, R Zhou, B Bao, S Xiao, K Li, Q Lin, L Zhu, Z Xia In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair Carbohydrate polymers, 2021-10-16;276(0):118752. 2021-10-16 [PMID: 34823781] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets Cell Reports, 2021-11-23;37(8):110037. 2021-11-23 [PMID: 34818536] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Amo-Aparic, J Garcia-Gar, I Francos-Qu, A Urpi, A Esteve-Cod, M Gut, A Quintana, R Lopez-Vale Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury Theranostics, 2021-10-03;11(20):9805-9820. 2021-10-03 [PMID: 34815787] (Bioassay, Mouse) |
Bioassay |
Mouse |
| KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages Nature Communications, 2021-11-17;12(1):6637. 2021-11-17 [PMID: 34789781] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Rozier, M Maumus, ATJ Maria, K Toupet, C Jorgensen, P Guilpain, D Noël Lung Fibrosis Is Improved by Extracellular Vesicles from IFNgamma-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis Cells, 2021-10-13;10(10):. 2021-10-13 [PMID: 34685707] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| JM Motta, VM Rumjanek, A Mantovani, M Locati Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation Biomedicines, 2021-10-04;9(10):. 2021-10-04 [PMID: 34680504] (Differentiation, Differentiation, Mouse) |
Differentiation, Differentiation |
Mouse |
| F Progatzky, M Shapiro, SH Chng, B Garcia-Cas, CH Classon, S Sevgi, A Laddach, AC Bon-Frauch, R Lasrado, M Rahim, EM Amaniti, S Boeing, K Shah, LJ Entwistle, A Suárez-Bon, MS Wilson, B Stockinger, V Pachnis Regulation of intestinal immunity and tissue repair by enteric glia Nature, 2021-10-20;599(7883):125-130. 2021-10-20 [PMID: 34671159] (Bioassay, Mouse) |
Bioassay |
Mouse |
| G Wang, L Xie, B Li, W Sang, J Yan, J Li, H Tian, W Li, Z Zhang, Y Tian, Y Dai A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Nature Communications, 2021-09-30;12(1):5733. 2021-09-30 [PMID: 34593794] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Z Qian, H Yang, H Li, C Liu, L Yang, Z Qu, X Li The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe-/- Mice through Modulating Macrophage Functions Biomedicines, 2021-09-03;9(9):. 2021-09-03 [PMID: 34572339] (Bioassay, Mouse) |
Bioassay |
Mouse |
| TD Popoola, ST Guetchueng, KJ Ritchie, O Awodele, NM Dempster, O Akinloye, SD Sarker, AA Fatokun Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea BMC complementary medicine and therapies, 2021-09-18;21(1):234. 2021-09-18 [PMID: 34537049] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Lee, G Kalugotla, H Ingle, R Rodgers, C Wu, Y Wang, Y Li, X Yang, J Zhang, NR Borella, H Deng, L Droit, R Hill, ST Peterson, C Desai, D Lawrence, Q Lu, MT Baldridge Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota Autophagy, 2021-09-14;0(0):1-16. 2021-09-14 [PMID: 34520306] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Choi, JA Bonanno Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium Investigative Ophthalmology & Visual Science, 2021-09-02;62(12):4. 2021-09-02 [PMID: 34499705] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Gluschko, A Farid, M Herb, D Grumme, M Krönke, M Schramm Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways Autophagy, 2021-09-05;0(0):1-15. 2021-09-05 [PMID: 34482812] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Osman, B Yan, Y Li, KD Pavelko, J Quandt, A Saadalla, MP Singh, M Kazemian, F Gounari, K Khazaie TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer Nature Immunology, 2021-08-12;0(0):. 2021-08-12 [PMID: 34385712] (Bioassay, Mouse) |
Bioassay |
Mouse |
| K Sumi, M Sakuda, K Munakata, K Nakamura, K Ashida alpha-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFalpha/IFNgamma Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube Nutrients, 2021-07-13;13(7):. 2021-07-13 [PMID: 34371902] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JH Kim, J Han, K Suk Protective Effects of Complement Component 8 Gamma Against Blood-Brain Barrier Breakdown Frontiers in Physiology, 2021-06-03;12(0):671250. 2021-06-03 [PMID: 34149451] (Cell Cultulre, Mouse) |
Cell Cultulre |
Mouse |
| J Sadek, DT Hall, B Colalillo, A Omer, AK Tremblay, V Sanguin-Ge, W Muller, S Di Marco, ME Bianchi, IE Gallouzi Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects Embo Molecular Medicine, 2021-06-07;0(0):e13591. 2021-06-07 [PMID: 34096686] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer Nature Communications, 2021-06-03;12(1):3299. 2021-06-03 [PMID: 34083537] (Bioassay, Mouse) |
Bioassay |
Mouse |
| MB Preda, CA Neculachi, IM Fenyo, AM Vacaru, MA Publik, M Simionescu, A Burlacu Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice Cell Death & Disease, 2021-06-02;12(6):566. 2021-06-02 [PMID: 34075029] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SS Qin, BJ Han, A Williams, KM Jackson, R Jewell, AC Chacon, EM Lord, DC Linehan, M Kim, A Reuben, SA Gerber, PA Prieto Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model Cancers, 2021-05-11;13(10):. 2021-05-11 [PMID: 34064795] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Z Wang, C Deng, Y Zheng Involvement of circRNAs in Proinflammatory Cytokines-Mediated &beta-Cell Dysfunction Mediators of Inflammation, 2021-05-04;2021(0):5566453. 2021-05-04 [PMID: 34054343] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Zhou, N Zhang, W Zhang, C Lu, F Xu The YAP/HIF-1&alpha/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation Cell & bioscience, 2021-05-12;11(1):84. 2021-05-12 [PMID: 33980319] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SL Vijayaraj, R Feltham, M Rashidi, D Frank, Z Liu, DS Simpson, G Ebert, A Vince, MJ Herold, A Kueh, JS Pearson, LF Dagley, JM Murphy, AI Webb, KE Lawlor, JE Vince The ubiquitylation of IL-1&beta limits its cleavage by caspase-1 and targets it for proteasomal degradation Nature Communications, 2021-05-11;12(1):2713. 2021-05-11 [PMID: 33976225] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| H Shi, L Sun, Y Wang, A Liu, X Zhan, X Li, M Tang, P Anderton, S Hildebrand, J Quan, S Ludwig, EMY Moresco, B Beutler N4BP1 negatively regulates NF-&kappaB by binding and inhibiting NEMO oligomerization Nature Communications, 2021-03-02;12(1):1379. 2021-03-02 [PMID: 33654074] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Tallón de, H Castañón, M Vermeer, N Núñez, K Silina, B Sobottka, J Urdinez, V Cecconi, H Yagita, F Movahedian, S Hiltbrunne, I Glarner, H Moch, S Tugues, B Becher, M van den Br CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer Nature Communications, 2021-02-03;12(1):769. 2021-02-03 [PMID: 33536445] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AH López-Ygle, E Burger, E Camanzo, AT Martin, AM Araujo, SF Kwok, F Yarovinsky T-bet-dependent ILC1- and NK cell-derived IFN-&gamma mediates cDC1-dependent host resistance against Toxoplasma gondii PloS Pathogens, 2021-01-19;17(1):e1008299. 2021-01-19 [PMID: 33465134] (Bioassay, Mouse) |
Bioassay |
Mouse |
| LM Sanmarco, MA Wheeler, C Gutiérrez-, CM Polonio, M Linnerbaue, FA Pinho-Ribe, Z Li, F Giovannoni, KV Batterman, G Scalisi, SEJ Zandee, ES Heck, M Alsuwailm, DL Rosene, B Becher, IM Chiu, A Prat, FJ Quintana Gut-licensed IFN&gamma+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes Nature, 2021-01-06;0(0):. 2021-01-06 [PMID: 33408417] (Bioassay, Mouse) |
Bioassay |
Mouse |
| R Contreras-, R Elizondo-V, N Luque-Camp, MJ Torres, C Pradenas, G Tejedor, MJ Paredes-Ma, AM Vega-Lette, M Campos-Mor, Y Rigual-Gon, K Oyarce, M Salgado, C Jorgensen, M Khoury, MLÁ Garcia-Rob, C Altamirano, F Djouad, P Luz-Crawfo The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential Theranostics, 2021-01-01;11(1):445-460. 2021-01-01 [PMID: 33391485] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JV Carratalá, E Brouillett, N Serna, A Sánchez-Ch, JM Sánchez, A Villaverde, A Arís, E Garcia-Fru, N Ferrer-Mir, F Malouin In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics Pharmaceutics, 2020-12-17;12(12):. 2020-12-17 [PMID: 33348529] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SA Rajput, MR Mirza, MI Choudhary Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells PLoS ONE, 2020-12-21;15(12):e0241349. 2020-12-21 [PMID: 33347462] (Bioassay, Rat) |
Bioassay |
Rat |
| KD Tuttle, KA Waugh, P Araya, R Minter, DJ Orlicky, M Ludwig, Z Andrysik, MA Burchill, BAJ Tamburini, C Sempeck, K Smith, R Granrath, D Tracy, J Baxter, JM Espinosa, KD Sullivan JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome Cell Rep, 2020-11-17;33(7):108407. 2020-11-17 [PMID: 33207208] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| CY Han, I Kang, M Omer, S Wang, T Wietecha, TN Wight, A Chait Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its anti-inflammatory properties JCI Insight, 2020-09-24;0(0):. 2020-09-24 [PMID: 32970631] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, Y Zhai, JC Wang, J Tcw, L Guo, A McKenzie, C Ming, X Zhou, M Wang, Y Sagi, AE Renton, BT Esposito, Y Kim, KR Sadleir, I Trinh, RA Rissman, R Vassar, B Zhang, DS Johnson, E Masliah, P Greengard, A Goate, YM Li The innate immunity protein IFITM3 modulates &gamma-secretase in Alzheimer's disease Nature, 2020-09-02;0(0):. 2020-09-02 [PMID: 32879487] (Bioassay, Mouse) |
Bioassay |
Mouse |
| K Nolan, G Verzosa, T Cleaver, D Tippimanch, LN DePledge, XJ Wang, C Young, A Le, R Doebele, H Li, SP Malkoski Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models Cancer Cell Int., 2020-08-28;20(0):417. 2020-08-28 [PMID: 32874131] (Bioassay, Mouse) |
Bioassay |
Mouse |
| ALJ Leite, DS Oliveira, LWR Mota, LCF Carvalho, FF Zimmermann, NCN Paiva, PMA Vieira, M de Lana, LCC Afonso, A Talvani Ectonucleotidases from trypomastigotes from different sources and various genetic backgrounds of Trypanosoma cruzi potentiate their infectivity and host inflammation Cytokine, 2020-08-28;136(0):155255. 2020-08-28 [PMID: 32866897] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Tur, S Pereira-Lo, T Vico, EA Marín, JP Muñoz, M Hernández-, PJ Cardona, A Zorzano, J Lloberas, A Celada Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity Cell Rep, 2020-08-25;32(8):108079. 2020-08-25 [PMID: 32846136] (Bioassay, Mouse) |
Bioassay |
Mouse |
| KA Meerschaer, PC Adelman, RL Friedman, KM Albers, HR Koerber, BM Davis Unique molecular characteristics of visceral afferents arising from different levels of the neuraxis: location of afferent somata predicts function and stimulus detection modalities J. Neurosci., 2020-08-19;0(0):. 2020-08-19 [PMID: 32817244] (Bioassay, Cell Culture, Mouse) |
Bioassay, Cell Culture |
Mouse |
| AJ Nelson, DJ Stephenson, RN Bone, CL Cardona, MA Park, YG Tusing, X Lei, G Kokotos, CL Graves, CE Mathews, J Kramer, MJ Hessner, CE Chalfant, S Ramanadham Lipid mediators and biomarkers associated with type 1 diabetes development JCI Insight, 2020-08-20;5(16):. 2020-08-20 [PMID: 32814707] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Castoldi, LB Monteiro, N van Teijli, DE Sanin, N Rana, M Corrado, AM Cameron, F Hässler, M Matsushita, G Caputa, RI Klein Gelt, J Büscher, J Edwards-Hi, EL Pearce, EJ Pearce Triacylglycerol synthesis enhances macrophage inflammatory function Nat Commun, 2020-08-14;11(1):4107. 2020-08-14 [PMID: 32796836] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Hong, D Yoon, Y Nam, D Seo, JH Kim, MS Kim, TY Lee, KS Kim, PW Ko, HW Lee, K Suk, SR Kim Lipopolysaccharide administration for a mouse model of cerebellar ataxia with neuroinflammation Sci Rep, 2020-08-07;10(1):13337. 2020-08-07 [PMID: 32770064] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Ettou, YL Jung, T Miyoshi, D Jain, K Hiratsuka, V Schumacher, ME Taglienti, R Morizane, PJ Park, JA Kreidberg Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury Sci Adv, 2020-07-24;6(30):eabb5460. 2020-07-24 [PMID: 32754639] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JPM Luiz, JE Toller-Kaw, PR Viacava, DC Nascimento, PT Pereira, AL Saraiva, DS Prado, M LeBert, E Giurisato, C Tournier, TM Cunha, FQ Cunha, V Quesniaux, B Ryffel, JC Alves-Filh MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression J. Leukoc. Biol., 2020-08-03;0(0):. 2020-08-03 [PMID: 32745297] (Bioassay, Mouse) |
Bioassay |
Mouse |
| R Kapetanovi, SF Afroz, D Ramnath, GM Lawrence, T Okada, JE Curson, J de Bruin, DP Fairlie, K Schroder, JC St John, A Blumenthal, MJ Sweet Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages Immunol. Cell Biol., 2020-07-20;0(0):. 2020-07-20 [PMID: 32686869] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| YH Wen, JN Lin, RS Wu, SH Yu, CJ Hsu, GF Tseng, HP Wu Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-O-&beta-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells Molecules, 2020-07-06;25(13):. 2020-07-06 [PMID: 32640539] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation Cell Rep, 2020-06-30;31(13):107820. 2020-06-30 [PMID: 32610123] (Bioassay, Mouse) |
Bioassay |
Mouse |
| CY Han, I Kang, IA Harten, JA Gebe, CK Chan, M Omer, KM Alonge, LJ den Hartig, D Gomes Kjer, L Goodspeed, S Subramania, S Wang, F Kim, DE Birk, TN Wight, A Chait Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity Cell Rep, 2020-06-30;31(13):107818. 2020-06-30 [PMID: 32610121] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Chaparala, H Tashkandi, AA Chumanevic, EE Witalison, A Windust, T Cui, M Nagarkatti, P Nagarkatti, LJ Hofseth Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2 Nutrients, 2020-06-21;12(6):. 2020-06-21 [PMID: 32575883] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JM Hildebrand, M Kauppi, IJ Majewski, Z Liu, AJ Cox, S Miyake, EJ Petrie, MA Silk, Z Li, MC Tanzer, G Brumatti, SN Young, C Hall, SE Garnish, J Corbin, MD Stutz, L Di Rago, P Gangatirka, EC Josefsson, K Rigbye, H Anderton, JA Rickard, A Tripaydoni, J Sheridan, TS Scerri, VE Jackson, PE Czabotar, JG Zhang, L Varghese, CC Allison, M Pellegrini, GM Tannahill, EC Hatchell, TA Willson, D Stockwell, CA de Graaf, J Collinge, A Hilton, N Silke, SK Spall, D Chau, V Athanasopo, D Metcalf, RM Laxer, AG Bassuk, BW Darbro, MA Fiatarone, N Vlahovich, D Hughes, M Kozlovskai, DB Ascher, K Warnatz, N Venhoff, J Thiel, C Biben, S Blum, J Reveille, MS Hildebrand, CG Vinuesa, P McCombe, MA Brown, BT Kile, C McLean, M Bahlo, SL Masters, H Nakano, PJ Ferguson, JM Murphy, WS Alexander, J Silke A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction Nat Commun, 2020-06-19;11(1):3150. 2020-06-19 [PMID: 32561755] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Chaparala, D Poudyal, H Tashkandi, EE Witalison, AA Chumanevic, JL Hofseth, I Nguyen, O Hardy, DL Pittman, MD Wyatt, A Windust, EA Murphy, M Nagarkatti, P Nagarkatti, LJ Hofseth Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Oncotarget, 2020-06-02;11(22):2026-2036. 2020-06-02 [PMID: 32547701] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Mc Fie, L Koneva, I Collins, CR Coveney, AM Clube, A Chanalaris, TL Vincent, JS Bezbradica, SN Sansom, AKT Wann Ciliary proteins specify the cell inflammatory response by tuning NF&kappaB signalling, independently of primary cilia J. Cell. Sci., 2020-07-08;133(13):. 2020-07-08 [PMID: 32503942] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| C Liu, YS Zhang, F Chen, XY Wu, BB Zhang, ZD Wu, JX Lei Immunopathology in schistosomiasis is regulated by TLR2,4- and IFN-gamma-activated MSC through modulating Th1/Th2 responses Stem Cell Res Ther, 2020-06-05;11(1):217. 2020-06-05 [PMID: 32503644] (Bioassay, Mouse) |
Bioassay |
Mouse |
| EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn Paracrine regulation and improvement of &beta-cell function by thioredoxin Redox Biol, 2020-05-16;34(0):101570. 2020-05-16 [PMID: 32473461] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| M Li, C Li, X Wu, T Chen, L Ren, B Xu, J Cao Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis Crit Care, 2020-05-27;24(1):268. 2020-05-27 [PMID: 32460890] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Q Yuan, J Miao, Q Yang, L Fang, Y Fang, H Ding, Y Zhou, L Jiang, C Dai, K Zen, Q Sun, J Yang Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation Cell Death Dis, 2020-05-11;11(5):355. 2020-05-11 [PMID: 32393782] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Bosteels C, Neyt K, Vanheerswynghels M, van Helden M, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams D, Tang S, Mayer J, Ronchese F, Scott C, Hammad H, Guilliams M, Lambrecht B Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection. Immunity, 2020-05-08;0(0):. 2020-05-08 [PMID: 32392463] (Mouse) |
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| J Falero-Per, N Sheibani, CM Sorenson Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells PLoS ONE, 2020-05-04;15(5):e0232779. 2020-05-04 [PMID: 32365083] (Bioassay, Mouse) |
Bioassay |
Mouse |
| TY Wu, JN Lin, ZY Luo, CJ Hsu, JS Wang, HP Wu 2,3,4',5-Tetrahydroxystilbene-2-O-&beta-D-Glucoside (THSG) Activates the Nrf2 Antioxidant Pathway and Attenuates Oxidative Stress-Induced Cell Death in Mouse Cochlear UB/OC-2 Cells Biomolecules, 2020-03-18;10(3):. 2020-03-18 [PMID: 32197448] (Bioassay, Mouse) |
Bioassay |
Mouse |
| R Kumar, PT Bunn, SS Singh, SS Ng, M Montes de, F De Labasti, SB Chauhan, N Singh, RJ Faleiro, CL Edwards, TCM Frame, M Sheel, RJ Austin, SW Lane, T Bald, MJ Smyth, GR Hill, SE Best, A Haque, D Corvino, N Waddell, L Koufarioti, P Mukhopadha, M Rai, J Chakravart, OP Singh, D Sacks, S Nylen, J Uzonna, S Sundar, CR Engwerda Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis Cell Rep, 2020-02-25;30(8):2512-2525.e9. 2020-02-25 [PMID: 32101732] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Giri, R Das, E Nylen, R Chinnadura, J Galipeau CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury Cell Rep, 2020-02-11;30(6):1923-1934.e4. 2020-02-11 [PMID: 32049021] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| X Gu, Y Zhang, D Li, H Cai, L Cai, Q Xu N6-methyladenosine demethylase FTO promotes M1 and M2 macrophage activation Cell. Signal., 2020-02-01;0(0):109553. 2020-02-01 [PMID: 32018056] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| S Steinmann, M Schoedsack, F Heinrich, PC Breda, A Ochel, G Tiegs, K Neumann Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells Sci Rep, 2020-01-23;10(1):1071. 2020-01-23 [PMID: 31974518] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| M Ichii, K Oritani, J Toda, H Saito, H Shi, H Shibayama, D Motooka, Y Kitai, R Muromoto, JI Kashiwakur, K Saitoh, D Okuzaki, T Matsuda, Y Kanakura Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress Haematologica, 2021-02-01;0(0):. 2021-02-01 [PMID: 31974192] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
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Bioassay |
Mouse |
| N Steffens, C Beuter-Gun, E Kravets, A Reich, L Legewie, K Pfeffer, D Degrandi Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection MBio, 2020-01-21;11(1):. 2020-01-21 [PMID: 31964735] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Yan, M Fernandez, J Wang, S Wu, R Wang, Z Lou, JB Moroney, CE Rivera, JR Taylor, H Gan, H Zan, D Kolvaskyy, D Liu, P Casali, Z Xu B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-kappaB Activation for Antibody Class-Switching J. Immunol., 2020-01-13;204(5):1146-1157. 2020-01-13 [PMID: 31932498] (Bioassay, Transgenic Mouse) |
Bioassay |
Transgenic Mouse |
| K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells BMC Cancer, 2020-01-08;20(1):25. 2020-01-08 [PMID: 31914969] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| J Liu, J Wei, C Wang, X Meng, H Chen, P Deng, M Huandike, H Zhang, X Li, L Chai The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-gamma-induced immune destruction of hematopoiesis in bone marrow cells BMC Complement Altern Med, 2019-12-09;19(1):356. 2019-12-09 [PMID: 31818289] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Augustine, S Pavlou, I Ali, K Harkin, E Ozaki, M Campbell, AW Stitt, H Xu, M Chen IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment J Neuroinflammation, 2019-12-03;16(1):251. 2019-12-03 [PMID: 31796062] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Ben-Yehuda, O Matcovitch, A Kertser, A Spinrad, M Prinz, I Amit, M Schwartz Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress Mol. Psychiatry, 2019-11-26;0(0):. 2019-11-26 [PMID: 31772304] (In Vivo, Mouse) |
In Vivo |
Mouse |
| D Zhang, Z Tang, H Huang, G Zhou, C Cui, Y Weng, W Liu, S Kim, S Lee, M Perez-Neut, J Ding, D Czyz, R Hu, Z Ye, M He, YG Zheng, HA Shuman, L Dai, B Ren, RG Roeder, L Becker, Y Zhao Metabolic regulation of gene expression by histone lactylation Nature, 2019-10-23;574(7779):575-580. 2019-10-23 [PMID: 31645732] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| Y Xu, Y Xu, Y Zhu, H Sun, C Juguilon, F Li, D Fan, L Yin, Y Zhang Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis Mol. Ther., 2019-09-12;0(0):. 2019-09-12 [PMID: 31604677] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Rahdar, A Rafiei, R Valipour-N The combination of Cytokines and albendazole therapy for prophylaxis and treatment of experimental ./hydatid cyst Acta Trop., 2019-10-02;201(0):105206. 2019-10-02 [PMID: 31586448] (In Vivo, Mouse) |
In Vivo |
Mouse |
| NW Zammit, SN Walters, KL Seeberger, PJ O'Connell, GS Korbutt, ST Grey A20 as an immune tolerance factor can determine islet transplant outcomes JCI Insight, 2019-11-01;4(21):. 2019-11-01 [PMID: 31581152] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Claser, SYT Nguee, A Balachande, S Wu Howland, E Becht, B Gunasegara, SV Hartimath, AWQ Lee, J Theng Then, C Bing Ong, EW Newell, J Goggi, L Guan Ng, L Renia Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury Nat Commun, 2019-09-18;10(1):4241. 2019-09-18 [PMID: 31534124] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt Phlda3 regulates beta cell survival during stress Sci Rep, 2019-09-06;9(1):12827. 2019-09-06 [PMID: 31492921] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Krashia, A Cordella, A Nobili, L La Barbera, M Federici, A Leuti, F Campanelli, G Natale, G Marino, V Calabrese, F Vedele, V Ghiglieri, B Picconi, G Di Lazzaro, T Schirinzi, G Sancesario, N Casadei, O Riess, S Bernardini, A Pisani, P Calabresi, MT Viscomi, CN Serhan, V Chiurchiù, M D'Amelio, NB Mercuri Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease Nat Commun, 2019-09-02;10(1):3945. 2019-09-02 [PMID: 31477726] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer Br. J. Cancer, 2019-08-16;121(7):556-566. 2019-08-16 [PMID: 31417189] (Bioassay, Mouse) |
Bioassay |
Mouse |
| PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein Mediators Inflamm., 2019-07-10;2019(0):9086758. 2019-07-10 [PMID: 31360120] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| Y Nakamura, S Miyagawa, S Yoshida, S Sasawatari, T Toyofuku, K Toda, Y Sawa Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model Sci Rep, 2019-07-25;9(1):10840. 2019-07-25 [PMID: 31346220] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Lindahl, AO Guerreiro-, SK Bedri, M Linnerbaue, M Lindén, N Abdelmagid, K Tandre, C Hollins, L Irving, C Glover, C Jones, L Alfredsson, L Rönnblom, I Kockum, M Khademi, M Jagodic, T Olsson IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis J. Immunol., 2019-07-10;0(0):. 2019-07-10 [PMID: 31292217] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| DG Ogando, M Choi, R Shyam, S Li, JA Bonanno Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress Redox Biol, 2019-06-23;26(0):101260. 2019-06-23 [PMID: 31254733] (Bioassay, Mouse) |
Bioassay |
Mouse |
| CC Pessoa, LC Reis, EM Ramos-Sanc, CM Orikaza, CC Plaza, EV de Castro, ACB Badaró, JUDS Yamamoto, V D'Almeida, H Goto, RA Mortara, F Real ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis PLoS Pathog., 2019-06-14;15(6):e1007834. 2019-06-14 [PMID: 31199856] (Bioassay, Mouse) |
Bioassay |
Mouse |
| GJ Song, MH Rahman, MK Jha, DP Gupta, SH Park, JH Kim, SH Lee, IK Lee, T Sim, YC Bae, WH Lee, K Suk A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain Front Pharmacol, 2019-05-20;10(0):543. 2019-05-20 [PMID: 31164822] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Ano, Y Yoshino, T Kutsukake, R Ohya, T Fukuda, K Uchida, A Takashima, H Nakayama Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive decline Aging (Albany NY), 2019-05-23;11(10):2949-2967. 2019-05-23 [PMID: 31121563] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AS Leal, SA Misek, EM Lisabeth, RR Neubig, KT Liby The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice Sci Rep, 2019-05-08;9(1):7072. 2019-05-08 [PMID: 31068602] (Bioassay, Mouse) |
Bioassay |
Mouse |
| TA Nguyen, BRC Smith, KD Elgass, SJ Creed, S Cheung, MD Tate, GT Belz, IP Wicks, SL Masters, KC Pang SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm J. Immunol., 2019-05-06;0(0):. 2019-05-06 [PMID: 31061008] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 2019-05-13;0(0):. 2019-05-13 [PMID: 31002437] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AM Giebel, S Hu, K Rajaram, R Finethy, E Toh, JA Brothwell, SG Morrison, RJ Suchland, BD Stein, J Coers, RP Morrison, DE Nelson Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture MBio, 2019-04-09;10(2):. 2019-04-09 [PMID: 30967464] (Bioassay, Mouse) |
Bioassay |
Mouse |
| L Li, Y Liu, S Li, Y Yang, C Zeng, W Rong, H Liang, M Zhang, X Zhu, K Kidder, Y Liu, Z Liu, K Zen Signal regulatory protein ? protects podocytes through promoting autophagic activity JCI Insight, 2019-03-19;5(0):. 2019-03-19 [PMID: 30888336] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy Nat. Med., 2019-03-04;0(0):. 2019-03-04 [PMID: 30833750] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Kita, Y Ano, A Inoue, J Aoki Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells Sci Rep, 2019-02-28;9(1):3135. 2019-02-28 [PMID: 30816271] (Bioassay, Mouse) |
Bioassay |
Mouse |
| PM Ryan, EH Stolte, LEE London, JM Wells, SL Long, SA Joyce, CGM Gahan, GF Fitzgerald, RP Ross, NM Caplice, C Stanton Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe BMC Microbiol., 2019-02-08;19(1):33. 2019-02-08 [PMID: 30736731] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Saeki, K Ishiyama, N Ishida, Y Tanaka, H Ohdan Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation Sci Rep, 2019-01-31;9(1):1022. 2019-01-31 [PMID: 30705364] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Ano, R Ohya, M Kita, Y Taniguchi, K Kondo Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation Molecules, 2019-01-28;24(3):. 2019-01-28 [PMID: 30696093] (Bioassay, Mouse) |
Bioassay |
Mouse |
| K Paduch, A Debus, B Rai, U Schleicher, C Bogdan Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1 J. Immunol., 2019-01-21;0(0):. 2019-01-21 [PMID: 30665936] (Bioassay, Mouse) |
Bioassay |
Mouse |
| LM Das, AM Binko, ZP Traylor, H Peng, KQ Lu Vitamin D improves sunburns by increasing autophagy in M2 macrophages Autophagy, 2019-01-24;0(0):1-14. 2019-01-24 [PMID: 30661440] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, AR Johnson, JJ Milner, MF Lim, JA Galanko, MA Beck, JE Bear, JD Rotty, L Bezavada, HS Smallwood, MA Puchowicz, J Liu, JW Locasale, DP Lee, BJ Bennett, ED Abel, JC Rathmell, L Makowski Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1 J. Immunol., 2019-01-18;0(0):. 2019-01-18 [PMID: 30659108] (Mouse) |
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| M Felder, A Kapur, AL Rakhmilevi, X Qu, PM Sondel, SD Gillies, J Connor, MS Patankar MUC16 suppresses human and murine innate immune responses Gynecol. Oncol., 2019-01-06;0(0):. 2019-01-06 [PMID: 30626487] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JD Jones, BP Sinder, D Paige, FN Soki, AJ Koh, S Thiele, Y Shiozawa, LC Hofbauer, S Daignault, H Roca, LK McCauley Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis Neoplasia, 2018-12-31;21(2):172-184. 2018-12-31 [PMID: 30591422] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt REV-ERB? Regulates TH17 Cell Development and Autoimmunity Cell Rep, 2018-12-26;25(13):3733-3749.e8. 2018-12-26 [PMID: 30590045] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Peng, Q Hu, F Yang, H Zhang, F Li, C Huang BCL6-Mediated Silencing of PD-1 Ligands in Germinal Center B Cells Maintains Follicular T Cell Population J. Immunol., 2018-12-19;0(0):. 2018-12-19 [PMID: 30567732] (Bioassay, Mouse) |
Bioassay |
Mouse |
| F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway Mol Brain, 2018-12-18;11(1):75. 2018-12-18 [PMID: 30563578] (ELISA (Standard), Mouse) |
ELISA (Standard) |
Mouse |
| G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy Cell Rep, 2018-11-20;25(8):2163-2176.e6. 2018-11-20 [PMID: 30463013] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Z Zuo, JX Shen, Y Pan, J Pu, YG Li, XH Shao, WP Wang Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage Cell. Physiol. Biochem., 2018-11-16;51(1):244-261. 2018-11-16 [PMID: 30448842] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AM Falcão, D van Brugge, S Marques, M Meijer, S Jäkel, E Agirre, Samudyata, EM Floriddia, DP Vanichkina, C Ffrench-Co, A Williams, AO Guerreiro-, G Castelo-Br Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis Nat. Med., 2018-11-12;0(0):. 2018-11-12 [PMID: 30420755] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SS Kim, HJ Jang, MY Oh, JH Lee, KS Kang Tetrahydrocurcumin Enhances Islet Cell Function and Attenuates Apoptosis in Mouse Islets Transplant. Proc., 2018-03-16;50(9):2847-2853. 2018-03-16 [PMID: 30401410] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Falero-Per, YS Song, Y Zhao, L Teixeira, CM Sorenson, N Sheibani Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells PLoS ONE, 2018-10-29;13(10):e0206756. 2018-10-29 [PMID: 30372497] (Bioassay, Mouse) |
Bioassay |
Mouse |
| F Zhang, O Ledue, M Jun, C Goulart, R Malley, YJ Lu Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms MBio, 2018-10-16;9(5):. 2018-10-16 [PMID: 30327437] (In Vivo, Mouse) |
In Vivo |
Mouse |
| C Farruggia, MB Kim, M Bae, Y Lee, TX Pham, Y Yang, MJ Han, YK Park, JY Lee Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners J. Nutr. Biochem., 2018-09-19;62(0):202-209. 2018-09-19 [PMID: 30308382] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Sang, T Danhorn, JN Peterson, AL Rankin, BP O'Connor, SM Leach, RM Torres, R Pelanda Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus Nat Commun, 2018-09-28;9(1):3973. 2018-09-28 [PMID: 30266981] (Bioassay, Mouse) |
Bioassay |
Mouse |
| E Mobarak, L Håversen, M Manna, M Rutberg, M Levin, R Perkins, T Rog, I Vattulaine, J Borén Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico Sci Rep, 2018-09-11;8(1):13600. 2018-09-11 [PMID: 30206272] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Ni, X Wang, X Yin, Y Li, X Liu, H Wang, X Liu, J Zhang, H Gao, B Shi, S Zhao Plectin protects podocytes from adriamycin-induced apoptosis and F-actin cytoskeletal disruption through the integrin ?6?4/FAK/p38 MAPK pathway J. Cell. Mol. Med., 2018-09-06;0(0):. 2018-09-06 [PMID: 30187999] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Kim, MJ Lee, JY Choi, DH Park, HB Kwak, S Moon, JW Koh, HK Shin, JK Ryu, CS Park, JH Park, JH Kang Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression Cell. Physiol. Biochem., 2018-08-09;48(5):1829-1842. 2018-08-09 [PMID: 30092568] (Stimulation, Mouse) |
Stimulation |
Mouse |
| SK Varanasi, NK Rajasagi, U Jaggi, BT Rouse Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions Mucosal Immunol, 2018-08-07;0(0):. 2018-08-07 [PMID: 30087443] (Mouse) |
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Mouse |
| Y Yin, H Hao, Y Cheng, L Zang, J Liu, J Gao, J Xue, Z Xie, Q Zhang, W Han, Y Mu Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice Cell Death Dis, 2018-07-09;9(7):760. 2018-07-09 [PMID: 29988034] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Martin, C Seignez, C Racoeur, N Isambert, Isambert N, N Mabrouk, Mabrouk N, A Scagliarin, Scagliarini A, S Reveneau, Reveneau S, L Arnould, Arnould L, A Bettaieb, JF Jeannin, Jeannin J, C Paul Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment. Oncotarget, 2018-06-19;9(47):28364-28378. 2018-06-19 [PMID: 29983866] (Bioassay, Rat) |
Bioassay |
Rat |
| YX Jiang, YY Dai, YF Pan, XM Wu, Y Yang, K Bian, DD Zhang Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways Evid Based Complement Alternat Med, 2018-05-22;2018(0):6714282. 2018-05-22 [PMID: 29951107] (Bioassay, Mouse) |
Bioassay |
Mouse |
| YM Nusse, AK Savage, P Marangoni, AKM Rosendahl-, TA Landman, FJ de Sauvage, RM Locksley, OD Klein Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche Nature, 2018-06-27;559(7712):109-113. 2018-06-27 [PMID: 29950724] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways Sci Rep, 2018-05-30;8(1):8414. 2018-05-30 [PMID: 29849089] (Bioassay, Mouse) |
Bioassay |
Mouse |
| DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting EMBO Mol Med, 2018-07-01;0(0):. 2018-07-01 [PMID: 29844217] (In Vivo, Mouse) |
In Vivo |
Mouse |
| H Su, Z Zhang, Z Liu, B Peng, C Kong, H Wang, Z Zhang, Y Xu Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells J. Biol. Chem., 2018-05-08;0(0):. 2018-05-08 [PMID: 29739853] (Bioassay, Mouse) |
Bioassay |
Mouse |
| BJ Morrison, JC Steel, JC Morris Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells BMC Cancer, 2018-04-26;18(1):469. 2018-04-26 [PMID: 29699516] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JP Ingram, S Tursi, T Zhang, W Guo, C Yin, M A Wynosky-, J van der He, KQ Cai, M Yamamoto, BB Finlay, IE Brodsky, SI Grivenniko, Ç Tükel, S Balachandr A Nonpyroptotic IFN-?-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo J. Immunol., 2018-04-13;0(0):. 2018-04-13 [PMID: 29654208] (Bioassay, Mouse, Transgenic Mouse) |
Bioassay |
Mouse, Transgenic Mouse |
| DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 2018-09-01;0(0):. 2018-09-01 [PMID: 29596569] (Bioassay, In Vivo, Mouse) |
Bioassay, In Vivo |
Mouse |
| D Joyce, M Fujino, M Morita, R Araki, J Fung, S Qian, L Lu, XK Li Induced pluripotent stem cells-derived myeloid-derived suppressor cells regulate the CD8+ T cell response Stem Cell Res, 2018-03-16;29(0):32-41. 2018-03-16 [PMID: 29574174] (Bioassay, Mouse) |
Bioassay |
Mouse |
| YW Yu, MX Li, ZY Zhang, H Yu The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice Int. J. Mol. Med., 2018-03-16;41(6):3577-3585. 2018-03-16 [PMID: 29568873] (Bioassay, Mouse) |
Bioassay |
Mouse |
| LA O'Reilly, TL Putoczki, LA Mielke, JT Low, A Lin, A Preaudet, MJ Herold, K Yaprianto, L Tai, A Kueh, G Pacini, RL Ferrero, R Gugasyan, Y Hu, M Christie, S Wilcox, R Grumont, MDW Griffin, L O'Connor, GK Smyth, M Ernst, P Waring, S Gerondakis, A Strasser Loss of NF-?B1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner Immunity, 2018-03-20;48(3):570-583.e8. 2018-03-20 [PMID: 29562203] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Y Liu, X Liang, W Dong, Y Fang, J Lv, T Zhang, R Fiskesund, J Xie, J Liu, X Yin, X Jin, D Chen, K Tang, J Ma, H Zhang, J Yu, J Yan, H Liang, S Mo, F Cheng, Y Zhou, H Zhang, J Wang, J Li, Y Chen, B Cui, ZW Hu, X Cao, F Xiao-Feng, B Huang Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation Cancer Cell, 2018-03-12;33(3):480-494.e7. 2018-03-12 [PMID: 29533786] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Sun, SY Chen RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function J. Immunol., 2018-03-05;0(0):. 2018-03-05 [PMID: 29507108] (Bioassay, Mouse) |
Bioassay |
Mouse |
| HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function Mol Metab, 2018-02-23;0(0):. 2018-02-23 [PMID: 29506910] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AS Chitre, MG Kattah, YY Rosli, M Pao, M Deswal, SG Deeks, PW Hunt, M Abdel-Mohs, LJ Montaner, CC Kim, A Ma, M Somsouk, JM McCune A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function PLoS Pathog., 2018-03-05;14(3):e1006806. 2018-03-05 [PMID: 29505600] (Bioassay, Mouse) |
Bioassay |
Mouse |
| K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park, JH Ju Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist PLoS ONE, 2018-02-26;13(2):e0193086. 2018-02-26 [PMID: 29481574] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Bhat, AS Bergot, N Waterhouse, IH Frazer Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells Oncotarget, 2017-12-14;9(5):6015-6027. 2017-12-14 [PMID: 29464051] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Chen, J Zhao, IH Ali, S Marry, J Augustine, M Bhuckory, A Lynch, A Kissenpfen, H Xu SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis Am. J. Pathol., 2018-02-13;0(0):. 2018-02-13 [PMID: 29452101] (Bioassay, Mouse) |
Bioassay |
Mouse |
| CES Guedes, BRS Dias, ALOA Petersen, KP Cruz, NJ Almeida, DR Andrade, JPB Menezes, VM Borges, PST Veras In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195 Mem. Inst. Oswaldo Cruz, 2018-02-05;113(4):e170345. 2018-02-05 [PMID: 29412342] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages Front Immunol, 2018-01-18;9(0):22. 2018-01-18 [PMID: 29403501] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| L Stoll, J Sobel, A Rodriguez-, C Guay, K Lee, MT Venø, J Kjems, DR Laybutt, R Regazzi Circular RNAs as novel regulators of ?-cell functions in normal and disease conditions Mol Metab, 2018-01-31;0(0):. 2018-01-31 [PMID: 29396373] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Nishikimi, YI Koyama, S Ishihara, S Kobayashi, C Tometsuka, M Kusubata, K Kuwaba, O Hayashida, S Hattori, K Katagiri Collagen-derived peptides modulate CD4T-cell differentiation and suppress allergic responses in mice Immun Inflamm Dis, 2018-02-01;0(0):. 2018-02-01 [PMID: 29388365] (Bioassay, Mouse) |
Bioassay |
Mouse |
| E Burger, A Araujo, A López-Ygle, MW Rajala, L Geng, B Levine, LV Hooper, E Burstein, F Yarovinsky Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation Cell Host Microbe, 2018-01-18;0(0):. 2018-01-18 [PMID: 29358083] (Stimulation, Mouse) |
Stimulation |
Mouse |
| M Farnoodian, CM Sorenson, N Sheibani PEDF Expression Affects the Oxidative and Inflammatory State of Choroidal Endothelial Cells Am. J. Physiol., Cell Physiol., 2018-01-10;0(0):. 2018-01-10 [PMID: 29351407] (Bioassay, Mouse) |
Bioassay |
Mouse |
| L Zhang, J Liu, F Zhou, W Wang, N Chen PGC-1? ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism Mol Med Rep, 2018-01-16;0(0):. 2018-01-16 [PMID: 29344670] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis Neurobiol. Dis., 2018-01-09;0(0):. 2018-01-09 [PMID: 29325869] (Bioassay, Mouse) |
Bioassay |
Mouse |
| H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis EBioMedicine, 2017-12-07;0(0):. 2017-12-07 [PMID: 29248508] (In Vivo, Mouse) |
In Vivo |
Mouse |
| R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis Cardiovasc Diabetol, 2017-11-06;16(1):143. 2017-11-06 [PMID: 29110715] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SA Samant, A Kanwal, VB Pillai, R Bao, MP Gupta The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy Sci Rep, 2017-09-19;7(1):11877. 2017-09-19 [PMID: 28928419] (Bioassay, Mouse) |
Bioassay |
Mouse |
| CA Sorgi, S Zarini, SA Martin, RL Sanchez, RF Scandiuzzi, MA Gijón, C Guijas, N Flamand, RC Murphy, LH Faccioli Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid Sci Rep, 2017-09-08;7(1):10981. 2017-09-08 [PMID: 28887514] (Bioassay, Mouse) |
Bioassay |
Mouse |
| SMP Vadevoo, JE Kim, GR Gunassekar, HK Jung, L Chi, DE Kim, SH Lee, SH Im, B Lee Interleukin 4 receptor-targeted pro-apoptotic peptide blocks tumor growth and metastasis by enhancing anti-tumor immunity Mol. Cancer Ther., 2017-09-06;0(0):. 2017-09-06 [PMID: 28878029] (Bioassay, Mouse) |
Bioassay |
Mouse |
| V Vaithiling, MDM Evans, DM Lewy, PA Bean, S Bal, BE Tuch Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted Sci Rep, 2017-08-30;7(1):10059. 2017-08-30 [PMID: 28855611] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Braverman, SA Stanley Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B J. Immunol., 2017-07-28;0(0):. 2017-07-28 [PMID: 28754681] (Bioassay, Mouse) |
Bioassay |
Mouse |
| G Nagalingam, CG Vinuesa, WJ Britton, BM Saunders Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation J. Immunol., 2017-07-26;0(0):. 2017-07-26 [PMID: 28747346] (Bioassay, Mouse) |
Bioassay |
Mouse |
| W Zhang, DG Ogando, ET Kim, MJ Choi, H Li, JM Tenessen, JA Bonanno Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3723-3731. 2017-07-01 [PMID: 28738416] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Foltz, A Napolitano, R Khan, B Clough, EM Hirst, EM Frickel TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles Sci Rep, 2017-07-12;7(1):5209. 2017-07-12 [PMID: 28701773] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
| X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis Sci Rep, 2017-07-11;7(1):5107. 2017-07-11 [PMID: 28698550] (Bioassay, Mouse) |
Bioassay |
Mouse |
| DA Cunha, M Cito, FA Grieco, C Cosentino, T Danilova, L Ladriere, M Lindahl, A Domanskyi, M Bugliani, P Marchetti, DL Eizirik, M Cnop Pancreatic ?-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF) J. Biol. Chem., 2017-07-11;0(0):. 2017-07-11 [PMID: 28698383] (Bioassay, Mouse) |
Bioassay |
Mouse |
| NH Overgaard, JL Cruz, JA Bridge, HJ Nel, IH Frazer, NL La Gruta, A Blumenthal, RJ Steptoe, JW Wells CD4(+)CD8?(+) double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin J. Leukoc. Biol., 2017-06-21;0(0):. 2017-06-21 [PMID: 28637895] (In Vivo, Mouse) |
In Vivo |
Mouse |
| A Kanbe, H Ito, Y Omori, A Hara, M Seishima The inhibition of NLRP3 signaling attenuates liver injury in an ?-galactosylceramide-induced hepatitis model Biochem. Biophys. Res. Commun., 2017-06-14;0(0):. 2017-06-14 [PMID: 28623127] (ELISA (Standard)) |
ELISA (Standard) |
|
| S Iwata, Y Mikami, HW Sun, SR Brooks, D Jankovic, K Hirahara, A Onodera, HY Shih, T Kawabe, K Jiang, T Nakayama, A Sher, JJ O'Shea, FP Davis, Y Kanno The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells Immunity, 2017-06-13;0(0):. 2017-06-13 [PMID: 28623086] (Bioassay, Mouse) |
Bioassay |
Mouse |
| P Bhat, G Leggatt, N Waterhouse, IH Frazer Interferon-? derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity Cell Death Dis, 2017-06-01;8(6):e2836. 2017-06-01 [PMID: 28569770] (Bioassay, Mouse) |
Bioassay |
Mouse |
| L Quinti, S Dayalan Na, U Träger, X Chen, K Kegel-Glea, D Llères, C Connolly, V Chopra, C Low, S Moniot, E Sapp, AR Tousley, P Vodicka, MJ Van Kanega, LS Kaltenbach, LA Crawford, M Fuszard, M Higgins, JRC Miller, RE Farmer, V Potluri, S Samajdar, L Meisel, N Zhang, A Snyder, R Stein, SM Hersch, LM Ellerby, E Weerapana, MA Schwarzsch, C Steegborn, BR Leavitt, A Degterev, SJ Tabrizi, DC Lo, M DiFiglia, LM Thompson, AT Dinkova-Ko, AG Kazantsev KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients Proc. Natl. Acad. Sci. U.S.A., 2017-05-22;0(0):. 2017-05-22 [PMID: 28533375] (Bioassay, Mouse) |
Bioassay |
Mouse |
| MG Ledesma-Co, N Adán, G Ortiz, M Solís-Guti, F López-Barr, G Martínez d, C Clapp Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis Arthritis Res. Ther., 2017-05-15;19(1):93. 2017-05-15 [PMID: 28506283] (In Vivo, Mouse) |
In Vivo |
Mouse |
| L Schnettger, A Rodgers, U Repnik, RP Lai, G Pei, M Verdoes, RJ Wilkinson, DB Young, MG Gutierrez A Rab20-Dependent Membrane Trafficking Pathway Controls M.�tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity Cell Host Microbe, 2017-05-10;21(5):619-628.e5. 2017-05-10 [PMID: 28494243] (Bioassay, Mouse) |
Bioassay |
Mouse |
| B Jee, P Sharma, K Katoch, B Joshi, SK Awasthi IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage Braz J Infect Dis, 2017-04-20;0(0):. 2017-04-20 [PMID: 28435012] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Park, H Sim, HI Kim, D Jeong, G Wu, SY Cho, YS Lee, HJ Kwon, K Lee CD11b regulates antibody class switching via induction of AID Mol. Immunol., 2017-04-11;87(0):47-59. 2017-04-11 [PMID: 28407558] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Dharmaraja, DL Fisk, CM Sorenson, N Sheibani, TL Belecky-Ad Microglia activation is essential for BMP7-mediated retinal reactive gliosis J Neuroinflammation, 2017-04-05;14(1):76. 2017-04-05 [PMID: 28381236] (Bioassay, Mouse) |
Bioassay |
Mouse |
| DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population Nat Commun, 2017-04-04;8(0):14919. 2017-04-04 [PMID: 28374774] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AJ Morales, JA Carrero, PJ Hung, AT Tubbs, JM Andrews, BT Edelson, B Calderon, CL Innes, RS Paules, JE Payton, BP Sleckman A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages Elife, 2017-03-31;6(0):. 2017-03-31 [PMID: 28362262] (Bioassay, Mouse) |
Bioassay |
Mouse |
| D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade J. Nutr. Biochem, 2017-03-06;44(0):11-21. 2017-03-06 [PMID: 28343084] (Bioassay, Mouse) |
Bioassay |
Mouse |
| V Piccolo, A Curina, M Genua, S Ghisletti, M Simonatto, A Sabò, B Amati, R Ostuni, G Natoli Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk Nat. Immunol, 2017-03-13;0(0):. 2017-03-13 [PMID: 28288101] (Bioassay, Mouse) |
Bioassay |
Mouse |
| DC Cockrell, CM Long, SJ Robertson, JG Shannon, HE Miller, L Myers, CL Larson, T Starr, PA Beare, RA Heinzen Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages PLoS ONE, 2017-03-09;12(3):e0173528. 2017-03-09 [PMID: 28278296] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Z Zhou, J Wan, X Hou, J Geng, X Li, X Bai MicroRNA-27a promotes podocyte injury via PPAR?-mediated ?-catenin activation in diabetic nephropathy Cell Death Dis, 2017-03-09;8(3):e2658. 2017-03-09 [PMID: 28277542] (Bioassay, Mouse) |
Bioassay |
Mouse |
| W Dawicki, C Li, J Town, X Zhang, JR Gordon Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells J. Allergy Clin. Immunol., 2016-10-26;139(5):1608-1620.e3. 2016-10-26 [PMID: 28277274] (ELISA (Standard), Mouse) |
ELISA (Standard) |
Mouse |
| R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, YK Young, YK Im, T Pawson, AE Koromilas, WJ Muller, KK Mann, CL Kleinman, J Ursini-Sie The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression Nat Commun, 2017-03-09;8(0):14638. 2017-03-09 [PMID: 28276425] (Bioassay, Mouse) |
Bioassay |
Mouse |
| JF Ma, BJ Sanchez, DT Hall, AK Tremblay, S Di Marco, IE Gallouzi STAT3 promotes IFN?/TNF?-induced muscle wasting in an NF-?B-dependent and IL-6-independent manner EMBO Mol Med, 2017-05-01;0(0):. 2017-05-01 [PMID: 28264935] (Bioassay, In Vivo, Mouse) |
Bioassay, In Vivo |
Mouse |
| L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4 J. Allergy Clin. Immunol, 2017-03-01;0(0):. 2017-03-01 [PMID: 28259445] (Bioassay, Mouse) |
Bioassay |
Mouse |
| W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway Cell Death Discov, 2017-02-27;3(0):16097. 2017-02-27 [PMID: 28250969] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier Metabolic origins of spatial organization in the tumor microenvironment Proc. Natl. Acad. Sci. U.S.A, 2017-02-28;0(0):. 2017-02-28 [PMID: 28246332] (Bioassay, Mouse) |
Bioassay |
Mouse |
| AD Villela, VD Rodrigues, AF Pinto, PL Wink, ZA Sánchez-Qu, GO Petersen, MM Campos, LA Basso, DS Santos Characterisation of iunH gene knockout strain from Mycobacterium tuberculosis Mem. Inst. Oswaldo Cruz, 2017-03-01;112(3):203-208. 2017-03-01 [PMID: 28225907] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Lau, J Cheung, A Navarro, S Lianoglou, B Haley, K Totpal, L Sanders, H Koeppen, P Caplazi, J McBride, H Chiu, R Hong, J Grogan, V Javinal, R Yauch, B Irving, M Belvin, I Mellman, JM Kim, M Schmidt Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice Nat Commun, 2017-02-21;8(0):14572. 2017-02-21 [PMID: 28220772] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy Sci Rep, 2017-02-17;7(0):42846. 2017-02-17 [PMID: 28211523] (Bioassay, Mouse) |
Bioassay |
Mouse |
| BA Szilagyi, J Triebus, C Kressler, M de Almeida, S Tierling, P Durek, M Mardahl, A Szilagyi, S Floess, J Huehn, U Syrbe, J Walter, JK Polansky, A Hamann Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4(+) memory T cells Mucosal Immunol, 2017-02-15;0(0):. 2017-02-15 [PMID: 28198363] (Bioassay, Mouse) |
Bioassay |
Mouse |
| M Jo, JH Kim, G Song, M Seo, E Mi Hwang, K Suk Astrocytic orosomucoid-2 modulates microglial activation and neuroinflammation J. Neurosci, 2017-02-13;0(0):. 2017-02-13 [PMID: 28193696] (Bioassay, Mouse) |
Bioassay |
Mouse |
| NM Abraham, L Liu, BL Jutras, AK Yadav, S Narasimhan, V Gopalakris, JM Ansari, KK Jefferson, F Cava, C Jacobs-Wag, E Fikrig Pathogen-mediated manipulation of arthropod microbiota to promote infection Proc. Natl. Acad. Sci. U.S.A, 2017-01-17;114(5):E781-E790. 2017-01-17 [PMID: 28096373] (In Vivo, Mouse) |
In Vivo |
Mouse |
| MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis Proc. Natl. Acad. Sci. U.S.A, 2017-01-09;114(4):E524-E533. 2017-01-09 [PMID: 28069965] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ofer Guttman Context-Specific and Immune Cell-Dependent Antitumor Activities of ?1-Antitrypsin Front Immunol, 2016-12-07;7(0):559. 2016-12-07 [PMID: 28003813] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Oksana Dmytriyeva Epobis is a Nonerythropoietic and Neuroprotective Agonist of the Erythropoietin Receptor with Anti-Inflammatory and Memory Enhancing Effects Mediators Inflamm, 2016-11-21;2016(0):1346390. 2016-11-21 [PMID: 27990061] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A K Kosmides Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma Biomaterials, 2016-12-02;118(0):16-26. 2016-12-02 [PMID: 27940380] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation Sci Rep, 2016-12-08;6(0):38387. 2016-12-08 [PMID: 27929069] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy J. Immunol., 2016-11-09;197(12):4750-4761. 2016-11-09 [PMID: 27913649] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis Sci Rep, 2016-12-01;6(0):37977. 2016-12-01 [PMID: 27905482] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Byeong Mo Kim Application of genetically engineered Salmonella typhimurium for interferon-gamma-induced therapy against melanoma Eur. J. Cancer, 2016-11-22;70(0):48-61. 2016-11-22 [PMID: 27883926] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Shawn Hayley Individual and interactive sex-specific effects of acute restraint and systemic IFN-? treatment on neurochemistry Neurochem. Int., 2016-11-19;0(0):. 2016-11-19 [PMID: 27876634] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections Sci Rep, 2016-11-15;6(0):37211. 2016-11-15 [PMID: 27845414] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Macrophages form functional vascular mimicry channels in vivo Sci Rep, 2016-11-11;6(0):36659. 2016-11-11 [PMID: 27834402] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Ali Mahmoudpou Proteasome Activators, PA28? and PA28?, Govern Development of Microvascular Injury in Diabetic Nephropathy and Retinopathy Int J Nephrol, 2016-10-18;2016(0):3846573. 2016-10-18 [PMID: 27830089] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Haiyan Peng Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments J. Neuroimmunol, 2016-08-05;299(0):35-44. 2016-08-05 [PMID: 27725119] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma Cancer Res, 2016-09-26;0(0):. 2016-09-26 [PMID: 27671674] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2? J Biol Chem, 2016-09-20;0(0):. 2016-09-20 [PMID: 27650501] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Lack of immunoediting in murine pancreatic cancer reversed with neoantigen JCI Insight, 2016-09-08;1(14):. 2016-09-08 [PMID: 27642636] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Niels Olsen Saraiva Camara Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development Immun Inflamm Dis, 2016-07-21;4(3):300-14. 2016-07-21 [PMID: 27621813] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Mechanisms Underlying Interferon-?-Induced Priming of Microglial Reactive Oxygen Species Production PLoS ONE, 2016-09-06;11(9):e0162497. 2016-09-06 [PMID: 27598576] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei PLoS Negl Trop Dis, 2016-08-25;10(8):e0004907. 2016-08-25 [PMID: 27560160] (Bioassay, Mouse) |
Bioassay |
Mouse |
| NADPH oxidases are essential for macrophage differentiation J Biol Chem, 2016-08-03;0(0):. 2016-08-03 [PMID: 27489105] (Bioassay, Mouse) |
Bioassay |
Mouse |
| HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis J Immunol, 2016-07-18;0(0):. 2016-07-18 [PMID: 27430718] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status Circ Res, 2016-07-14;0(0):. 2016-07-14 [PMID: 27418629] (Bioassay, Mouse) |
Bioassay |
Mouse |
| G2A Signaling Dampens Colitic Inflammation via Production of IFN-? J Immunol, 2016-07-08;0(0):. 2016-07-08 [PMID: 27402702] (In Vivo, Mouse) |
In Vivo |
Mouse |
| L R Batista-Si Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages Sci Rep, 2016-06-10;6(0):27632. 2016-06-10 [PMID: 27282338] (Bioassay, Mouse) |
Bioassay |
Mouse |
| LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses J. Biol. Chem., 2016-05-23;291(30):15830-40. 2016-05-23 [PMID: 27226638] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription Nat Commun, 2016-05-23;7(0):11624. 2016-05-23 [PMID: 27211851] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization J Immunol, 2016-05-04;196(11):4536-43. 2016-05-04 [PMID: 27183603] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor Nat Med, 2016-05-09;0(0):. 2016-05-09 [PMID: 27158906] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Platelets Guide Leukocytes to Their Sites of Extravasation PLoS Biol, 2016-05-06;14(5):e1002459. 2016-05-06 [PMID: 27152726] (In Vivo, Mouse) |
In Vivo |
Mouse |
| P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells Oncogene, 2016-04-25;0(0):. 2016-04-25 [PMID: 27109100] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis J Immunol, 2016-04-06;0(0):. 2016-04-06 [PMID: 27053763] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, Smith I, Tothova Z, Wilen C, Orchard R, Virgin H, Listgarten J, Root D Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol, 2016-01-18;34(2):184-91. 2016-01-18 [PMID: 26780180] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Somintara S, Leardkamolkarn V, Suttiarporn P, Mahatheeranont S Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia. PLoS ONE, 2016-01-11;11(1):e0146869. 2016-01-11 [PMID: 26752299] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol, 2015-09-21;195(9):4415-25. 2015-09-21 [PMID: 26392463] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Cohen H, Ward A, Hamidzadeh K, Ravid K, Mosser D IFN-gamma Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response. J Immunol, 2015-09-09;195(8):3828-37. 2015-09-09 [PMID: 26355158] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation. J Immunol, 2015-09-09;195(8):3531-6. 2015-09-09 [PMID: 26355150] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Howland S, Poh C, Renia L Activated Brain Endothelial Cells Cross-Present Malaria Antigen. PLoS Pathog, 2015-06-05;11(6):e1004963. 2015-06-05 [PMID: 26046849] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate. Eur J Immunol, 2015-05-28;45(9):2494-503. 2015-05-28 [PMID: 25959978] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Beck B, Kim H, O'Brien R, Jadus M, Gillespie G, Cloud G, Hoa N, Langford C, Lopez R, Harkins L, Lamb L Dynamics of Circulating gammadelta T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma. PLoS ONE, 2015-05-08;10(5):e0122387. 2015-05-08 [PMID: 25955158] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Alam I, Gray A, Acton D, Gerard-O'Riley R, Reilly A, Econs M Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice. J Bone Miner Res, 2015-05-14;30(11):2005-13. 2015-05-14 [PMID: 25943708] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Guay C, Menoud V, Rome S, Regazzi R Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells. Cell Commun Signal, 2015-03-19;13(0):17. 2015-03-19 [PMID: 25880779] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Noh K, Son K, Jung I, Kang T, Choi C, Park Y Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression. J Biol Chem, 2015-03-26;290(19):12394-402. 2015-03-26 [PMID: 25814664] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis. PLoS ONE, 2015-03-20;10(3):e0120327. 2015-03-20 [PMID: 25793532] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Jha A, Huang S, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, Chmielewski K, Stewart K, Ashall J, Everts B, Pearce E, Driggers E, Artyomov M Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. Immunity, 2015-03-17;42(3):419-30. 2015-03-17 [PMID: 25786174] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences. J Invest Dermatol, 2015-03-04;135(7):1771-80. 2015-03-04 [PMID: 25739051] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Sag D, Cekic C, Wu R, Linden J, Hedrick C The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun, 2015-02-27;6(0):6354. 2015-02-27 [PMID: 25724068] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, Fung H, Albrecht S, Alexandropoulos K, McCauley D, Chook Y, Kuhlmann T, Kidd G, Shacham S, Casaccia P Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat Neurosci, 2015-02-23;18(4):511-20. 2015-02-23 [PMID: 25706475] (Mouse) |
|
Mouse |
| Goodsmith N, Guo X, Vandal O, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P, Schnappinger D, Ehrt S Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice. PLoS Pathog, 2015-02-06;11(2):e1004645. 2015-02-06 [PMID: 25658098] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization. Autophagy, 2015-01-01;11(2):271-84. 2015-01-01 [PMID: 25650776] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med, 2015-03-01;7(3):240-58. 2015-03-01 [PMID: 25637383] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, Ozato K, Natoli G A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages. Genes Dev, 2015-01-30;29(4):394-408. 2015-01-30 [PMID: 25637355] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ma F, Li B, Liu S, Iyer S, Yu Y, Wu A, Cheng G Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS. J Immunol, 2015-01-21;194(4):1545-54. 2015-01-21 [PMID: 25609843] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Oficjalska K, Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, Corr S, Kay E, O'Neill L, Mills K, Creagh E Protective role for caspase-11 during acute experimental murine colitis. J Immunol, 2014-12-29;194(3):1252-60. 2014-12-29 [PMID: 25548224] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, Uchino M, Ando Y, Nagafuchi S, Nishimura Y, Senju S Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells. PLoS ONE, 2014-12-18;9(12):e115198. 2014-12-18 [PMID: 25522369] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Cancer Res, 2014-11-20;75(2):330-43. 2014-11-20 [PMID: 25414138] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Dohi , Kenji, Kraemer , Brian C, Erickson , Michelle, McMillan , Pamela J, Kovac , Andrej, Flachbartova , Zuzana, Hansen , Kim M, Shah , Gul N, Sheibani , Nader, Salameh , Therese, Banks , William Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. PLoS ONE, 2014-09-24;9(9):e108034. 2014-09-24 [PMID: 25251220] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway. Elife, 2014-09-16;3(0):e02809. 2014-09-16 [PMID: 25233132] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Newstead S, Gates A, Hartley M, Rowland C, Williamson E, Lukaszewski R Control of intracellular Francisella tularensis by different cell types and the role of nitric oxide. J Immunol Res, 2014-07-21;2014(0):694717. 2014-07-21 [PMID: 25170518] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Mulye M, Bechill M, Grose W, Ferreira V, Lafontaine E, Wooten R Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages. PLoS Negl Trop Dis, 2014-08-21;8(8):e2988. 2014-08-21 [PMID: 25144195] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins A, Keech A, Humphries K, Gu X, Elliott M, Xia X, Ma J Peroxisome proliferator-activated receptor alpha protects capillary pericytes in the retina. Am J Pathol, 2014-08-07;184(10):2709-20. 2014-08-07 [PMID: 25108226] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b. J Immunol, 2014-08-04;193(6):3036-44. 2014-08-04 [PMID: 25092892] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Oslund K, Zhou X, Lee B, Zhu L, Duong T, Shih R, Baumgarth N, Hung L, Wu R, Chen Y Synergistic up-regulation of CXCL10 by virus and IFN gamma in human airway epithelial cells. PLoS ONE, 2014-07-17;9(7):e100978. 2014-07-17 [PMID: 25033426] (Bioassay, In Vivo, Mouse) |
Bioassay, In Vivo |
Mouse |
| Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis. Nat Commun, 2014-07-14;5(0):4436. 2014-07-14 [PMID: 25019241] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, Kalkhoven E, Nieuwenhuis E, Clevers H Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-gamma. J Exp Med, 2014-06-30;211(7):1393-405. 2014-06-30 [PMID: 24980747] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Chen D, Goswami C, Burnett R, Anjanappa M, Bhat-Nakshatri P, Muller W, Nakshatri H Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle. Cancer Res, 2014-06-30;74(16):4270-81. 2014-06-30 [PMID: 24980554] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Stoolman J, Duncker P, Huber A, Segal B Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis. J Immunol, 2014-06-13;193(2):564-70. 2014-06-13 [PMID: 24928987] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Dang , Shipeng, Xu , Huanbai, Xu , Congfeng, Cai , Wei, Li , Qian, Cheng , Yiji, Jin , Min, Wang , Ru-Xing, Peng , Yongde, Zhang , Yi, Wu , Changpin, He , Xiaozhou, Wan , Bing, Zhang , Yanyun Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy, 2014-05-14;10(7):1301-15. 2014-05-14 [PMID: 24905997] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Hong B, Li H, Lu Y, Zhang M, Zheng Y, Qian J, Yi Q USP18 is crucial for IFN-gamma-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity. Mol Cancer, 2014-05-31;13(0):132. 2014-05-31 [PMID: 24884733] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Falconer J, Lowes K, Furmanski A, Dyson J, Ng W, Robinson J Intramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan. Immunology, 2014-05-01;142(1):101-110. 2014-05-01 [PMID: 24843873] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Hirosue S, Vokali E, Raghavan V, Rincon-Restrepo M, Lund A, Corthesy-Henrioud P, Capotosti F, Halin Winter C, Hugues S, Swartz M Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells. J Immunol, 2014-05-02;192(11):5002-11. 2014-05-02 [PMID: 24795456] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Bhatt S, Qin J, Bennett C, Qian S, Fung J, Hamilton T, Lu L All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function. J Immunol, 2014-04-30;192(11):5098-108. 2014-04-30 [PMID: 24790153] (Bioassay, Mouse) |
Bioassay |
Mouse |
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ELISA (Standard) |
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Bioassay |
Mouse |
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Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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| Sidney L, Kirkham G, Buttery L Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma. Stem Cells Dev, 2014-01-23;23(6):605-17. 2014-01-23 [PMID: 24192281] (Bioassay, Mouse) |
Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
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| Achard , Maud E S, Chen , Kaiwen W, Sweet , Matthew, Watts , Rebecca, Schroder , Kate, Schembri , Mark A, McEwan , Alastair An antioxidant role for catecholate siderophores in Salmonella. Biochem J, 2013-09-15;454(3):543-9. 2013-09-15 [PMID: 23805839] (Bioassay, Mouse) |
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Mouse |
| Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, He W, Yang J, Dai C Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/beta-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria. J Biol Chem, 2013-06-26;288(32):23368-79. 2013-06-26 [PMID: 23803607] (Bioassay, Mouse) |
Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
| Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma. PLoS ONE, 2013-04-17;8(4):e61446. 2013-04-17 [PMID: 23613854] (Bioassay, Mouse) |
Bioassay |
Mouse |
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In Vivo |
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| Park S, Dimaio T, Liu W, Wang S, Sorenson C, Sheibani N Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-beta signaling pathways. J Cell Sci, 2013-02-15;126(0):1392-405. 2013-02-15 [PMID: 23418351] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Moran C, Jose R, Moxon J, Roomberg A, Norman P, Rush C, Korner H, Golledge J Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes. Arterioscler Thromb Vasc Biol, 2013-02-07;33(4):814-21. 2013-02-07 [PMID: 23393391] (Bioassay, Mouse) |
Bioassay |
Mouse |
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Bioassay |
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Bioassay |
Mouse |
| Kim H, Chung D IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner. Mucosal Immunol, 2012-08-15;6(2):347-57. 2012-08-15 [PMID: 22892939] (Bioassay, Mouse) |
Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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In Vivo |
Mouse |
| Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma. Am. J. Pathol., 2011-10-26;180(1):365-74. 2011-10-26 [PMID: 22037251] (In Vivo, Mouse) |
In Vivo |
Mouse |
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Bioassay |
Mouse |
| Nicholls HT, Kowalski G, Kennedy DJ Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. Diabetes, 2011-03-04;60(4):1100-10. 2011-03-04 [PMID: 21378177] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Sato N, Sabzevari H, Fu S, Ju W, Petrus MN, Bamford RN, Waldmann TA, Tagaya Y Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15R alpha. Blood, 2011-02-08;117(15):4032-40. 2011-02-08 [PMID: 21304101] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Liang S, Krauss JL, Domon H, McIntosh ML, Hosur KB, Qu H, Li F, Tzekou A, Lambris JD, Hajishengallis G The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss. J. Immunol., 2010-12-13;186(2):869-77. 2010-12-13 [PMID: 21149611] (Bioassay, Mouse) |
Bioassay |
Mouse |
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In Vivo |
Mouse |
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In Vivo |
Mouse |
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Bioassay |
Mouse |
| Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages. J. Immunol., 2010-07-21;185(4):2044-50. 2010-07-21 [PMID: 20660352] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| Craig EA, Craig E, Austin AF, Austin A, Vaillancourt RR, Vaillancourt R, Barnett JV, Camenisch TD, Camenisch T TGFbeta2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion. Exp Cell Res, 2010-07-13;316(20):3397-405. 2010-07-13 [PMID: 20633555] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Strissel KJ, DeFuria J, Shaul ME, Bennett G, Greenberg AS, Obin MS T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice. Obesity (Silver Spring), 2010-01-28;18(10):1918-25. 2010-01-28 [PMID: 20111012] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway. J. Immunol., 2009-10-19;183(10):6135-44. 2009-10-19 [PMID: 19841165] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Mucosal Immunol, 2009-10-07;3(1):40-8. 2009-10-07 [PMID: 19812544] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wu J, Wrathall JR, Schachner M Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. Glia, 2010-02-01;58(3):315-28. 2010-02-01 [PMID: 19672967] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Ilarregui JM, Croci DO, Bianco GA, Toscano MA, Salatino M, Vermeulen ME, Geffner JR, Rabinovich GA Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat. Immunol., 2009-08-09;10(9):981-91. 2009-08-09 [PMID: 19668220] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J. Immunol., 2009-07-27;183(4):2642-9. 2009-07-27 [PMID: 19635910] (Bioassay, Mouse) |
Bioassay |
Mouse |
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Bioassay |
Mouse |
| Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9. 2009-03-16 [PMID: 19289819] (ELISA (Standard), In Vivo, Mouse) |
ELISA (Standard), In Vivo |
Mouse |
| Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis. Microbes Infect., 2009-03-13;11(4):524-30. 2009-03-13 [PMID: 19286469] (ELISA (Standard)) |
ELISA (Standard) |
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In Vivo |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay, In Vivo |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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ELISA (Standard) |
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In Vivo |
Mouse |
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In Vivo |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
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Bioassay |
Mouse |
| Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis. J. Immunol., 2006-12-15;177(12):8650-7. 2006-12-15 [PMID: 17142765] (ELISA (Standard)) |
ELISA (Standard) |
|
| Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model. J. Immunol., 2006-09-01;177(5):3388-97. 2006-09-01 [PMID: 16920980] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1. Proc. Natl. Acad. Sci. U.S.A., 2006-07-24;103(31):11784-9. 2006-07-24 [PMID: 16864778] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J. Clin. Invest., 2006-03-23;116(4):905-15. 2006-03-23 [PMID: 16557302] (Bioassay, Mouse) |
Bioassay |
Mouse |
| An HJ, Jeong HJ, Um JY, Kim HM, Hong SH Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. J Ethnopharmacol, 2006-03-10;106(3):418-24. 2006-03-10 [PMID: 16530364] (Bioassay, In Vivo, Mouse) |
Bioassay, In Vivo |
Mouse |
| Zhang F, Lee J, Wang D, Dong Z Differential Growth of IFN-beta-Engineered Tumor Cells in Nude and IFN Receptor-Null Mice. J. Interferon Cytokine Res., 2006-02-01;26(2):108-18. 2006-02-01 [PMID: 16487031] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol. Cell. Neurosci., 2005-11-16;31(1):149-60. 2005-11-16 [PMID: 16297637] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J. Virol., 2005-10-01;79(20):12828-39. 2005-10-01 [PMID: 16188985] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Osuchowski MF, Siddiqui J, Copeland S, Remick DG Sequential ELISA to profile multiple cytokines from small volumes. J. Immunol. Methods, 2005-07-01;302(1):172-81. 2005-07-01 [PMID: 16023134] (ELISA (Standard)) |
ELISA (Standard) |
|
| Kamath AT, Sheasby CE, Tough DF Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma. J. Immunol., 2005-01-15;174(2):767-76. 2005-01-15 [PMID: 15634897] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Murphey ED, Herndon DN, Sherwood ER Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression. Infect. Immun., 2004-12-01;72(12):6892-901. 2004-12-01 [PMID: 15557610] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J. Biol. Chem., 2004-10-13;279(52):54405-15. 2004-10-13 [PMID: 15485838] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow. J. Immunol., 2004-06-15;172(12):7408-16. 2004-06-15 [PMID: 15187118] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis. J. Immunol., 2004-05-15;172(10):6476-81. 2004-05-15 [PMID: 15128840] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. J. Immunol., 2004-03-15;172(6):3678-85. 2004-03-15 [PMID: 15004171] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol., 2003-12-15;171(12):6466-77. 2003-12-15 [PMID: 14662846] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW Intracellular thiols contribute to Th2 function via a positive role in IL-4 production. J. Immunol., 2003-11-15;171(10):5107-15. 2003-11-15 [PMID: 14607909] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, Housseau F Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. J. Exp. Med., 2003-07-07;198(1):31-8. 2003-07-07 [PMID: 12847135] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. Am. J. Pathol., 2003-05-01;162(5):1475-86. 2003-05-01 [PMID: 12707030] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis. J. Immunol., 2002-05-01;168(9):4764-71. 2002-05-01 [PMID: 11971027] (In Vivo, Mouse) |
In Vivo |
Mouse |
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Show All 443 Publications.
Collapse Publications.
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![SDS-PAGE TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg)
![Bioactivity TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg)
![SEC-MALS TNF-alpha [Unconjugated]](https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg)
![Bioactivity IL-4 [Unconjugated]](https://images.novusbio.com/images/protein/6507-ilcf_recombinant-human-il-4-cho-expressed-protein-cf-bioactivity-272020133214.jpg)
![Bioactivity IL-2 [Unconjugated]](https://images.novusbio.com/images/202-il_recombinant-human-il-2-protein-bioactivity-174202314946.jpg)
![N/A IL-10 [Biotin]](https://images.novusbio.com/images2/DATA_IL10_DY417_ELISA_2014.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/DATA_IL6_M6000_ELISA_936.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/IL-6_M6000_ELISA_415.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg)
![N/A IL-5 [HRP]](https://images.novusbio.com/images2/IL-5_M5000_ELISA_237.jpg)
![N/A IL-5 [HRP]](https://images.novusbio.com/images2/DATA_IL5_M5000_ELISA_935.jpg)
![SDS-PAGE IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_304.jpg)
![Bioactivity IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_306.jpg)
![SEC-MALS IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images/201-lb_recombinant-human-il-1-beta-il-1f2-protein-sec-mals-123202491556.jpg)
![Bioactivity CTLA-4 [Unconjugated]](https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg)
![N/A IL-13 [Biotin]](https://images.novusbio.com/images2/DATA_IL13_DY413_ELISA_2010.jpg)