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In Vivo |
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Mouse |
Garcia-Alonso V, Lopez-Vicario C, Titos E, Moran-Salvador E, Gonzalez-Periz A, Rius B, Parrizas M, Werz O, Arroyo V, Claria J Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor gamma (PPARgamma) in the conversion of white-to-brown adipocytes. J Biol Chem, 2013-08-13;288(39):28230-42. 2013-08-13 [PMID: 23943621] (Bioassay, Mouse) |
Bioassay |
Mouse |
Hunter , K E, Palermo , C, Kester , J C, Simpson , K, Li , J-P, Tang , L H, Klimstra , D S, Vlodavsky , I, Joyce , J A Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors. Oncogene, 2013-05-06;33(14):1799-808. 2013-05-06 [PMID: 23644656] (Bioassay, Mouse) |
Bioassay |
Mouse |
Karwacki-Neisius V, Goke J, Osorno R, Halbritter F, Ng J, Weisse A, Wong F, Gagliardi A, Mullin N, Festuccia N, Colby D, Tomlinson S, Ng H, Chambers I Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog. Cell Stem Cell, 2013-05-02;12(5):531-45. 2013-05-02 [PMID: 23642364] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
Ngamjariyawat A, Turpaev K, Vasylovska S, Kozlova E, Welsh N Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death. PLoS ONE, 2013-04-17;8(4):e61828. 2013-04-17 [PMID: 23613946] (Bioassay, Mouse) |
Bioassay |
Mouse |
Gomez-Ospina , Natalia, Panagiotakos , Georgia, Portmann , Thomas, Pasca , Sergiu P, Rabah , Dania, Budzillo , Agata, Kinet , Jean Pie, Dolmetsch , Ricardo A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT. PLoS ONE, 2013-04-16;8(4):e60526. 2013-04-16 [PMID: 23613729] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
Najm , Fadi J, Lager , Angela M, Zaremba , Anita, Wyatt , Krysta, Caprariello , Andrew V, Factor , Daniel C, Karl , Robert T, Maeda , Tadao, Miller , Robert H, Tesar , Paul J Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol, 2013-04-14;31(5):426-33. 2013-04-14 [PMID: 23584611] (Bioassay, Mouse) |
Bioassay |
Mouse |
Zhang G, Panigrahy D, Mahakian L, Yang J, Liu J, Stephen Lee K, Wettersten H, Ulu A, Hu X, Tam S, Hwang S, Ingham E, Kieran M, Weiss R, Ferrara K, Hammock B Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A, 2013-04-03;110(16):6530-5. 2013-04-03 [PMID: 23553837] (In Vivo, Mouse) |
In Vivo |
Mouse |
Kharitonenkov , Alexei, Beals , John M, Micanovic , Radmila, Strifler , Beth A, Rathnachalam , Radhakri, Wroblewski , Victor J, Li , Shun, Koester , Anja, Ford , Amy M, Coskun , Tamer, Dunbar , James D, Cheng , Christin, Frye , Christop, Bumol , Thomas F, Moller , David E Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. PLoS ONE, 2013-03-11;8(3):e58575. 2013-03-11 [PMID: 23536797] (Stimulation, Mouse) |
Stimulation |
Mouse |
Liu , Xian Shu, Chopp , Michael, Wang , Xin Li, Zhang , Li, Hozeska-Solgot , Ann, Tang , Tao, Kassis , Haifa, Zhang , Rui Lan, Chen , Charles, Xu , Jennifer, Zhang , Zheng Ga MicroRNA-17-92 cluster mediates the proliferation and survival of neural progenitor cells after stroke. J Biol Chem, 2013-03-19;288(18):12478-88. 2013-03-19 [PMID: 23511639] (Bioassay, Mouse) |
Bioassay |
Mouse |
Brown A, Muthukrishnan S, Guay J, Adams D, Schafer D, Fetting J, Oxburgh L Role for compartmentalization in nephron progenitor differentiation. Proc Natl Acad Sci U S A, 2013-03-04;110(12):4640-5. 2013-03-04 [PMID: 23487745] (Bioassay, Mouse) |
Bioassay |
Mouse |
Hoffman J, Wu C, Merrill B Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification. Development, 2013-03-13;140(8):1665-75. 2013-03-13 [PMID: 23487311] (Bioassay, Mouse) |
Bioassay |
Mouse |
Itoh , Yasuhiro, Moriyama , Yasunobu, Hasegawa , Tsuyoshi, Endo , Takaho A, Toyoda , Tetsuro, Gotoh , Yukiko Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci, 2013-02-24;16(4):416-25. 2013-02-24 [PMID: 23434913] (Bioassay, Mouse) |
Bioassay |
Mouse |
Tucker B, Anfinson K, Mullins R, Stone E, Young M Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med, 2012-12-27;2(1):16-24. 2012-12-27 [PMID: 23283489] (Bioassay, Mouse) |
Bioassay |
Mouse |
Fraineau S, Monvoisin A, Clarhaut J, Talbot J, Simonneau C, Kanthou C, Kanse S, Philippe M, Benzakour O The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner. Blood, 2012-10-12;120(25):5073-83. 2012-10-12 [PMID: 23065156] (Bioassay, Mouse) |
Bioassay |
Mouse |
Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutierrez OM, Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ, Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St John Sutton M, Ojo A, Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW, Kuro-o M, Kusek JW, Keane MG, Wolf M FGF23 induces left ventricular hypertrophy. J. Clin. Invest., 2011-10-10;121(11):4393-408. 2011-10-10 [PMID: 21985788] (Bioassay, Mouse) |
Bioassay |
Mouse |
Strissel KJ, DeFuria J, Shaul ME, Bennett G, Greenberg AS, Obin MS T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice. Obesity (Silver Spring), 2010-01-28;18(10):1918-25. 2010-01-28 [PMID: 20111012] (Bioassay, Mouse) |
Bioassay |
Mouse |
Nakao S, Maruyama K, Zandi S, Melhorn MI, Taher M, Noda K, Nusayr E, Doetschman T, Hafezi-Moghadam A Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains. FASEB J., 2009-10-26;24(2):504-13. 2009-10-26 [PMID: 19858096] (In Vivo, Mouse) |
In Vivo |
Mouse |
Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specification. EMBO J., 2009-10-22;29(1):55-67. 2009-10-22 [PMID: 19851287] (Bioassay, Xenopus) |
Bioassay |
Xenopus |
Mercapide J, Rappa G, Anzanello F Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma. Int. J. Cancer, 2010-03-01;126(5):1206-15. 2010-03-01 [PMID: 19653275] (Bioassay, Mouse) |
Bioassay |
Mouse |
Chia SL, Sawaji Y, Burleigh A, McLean C, Inglis J, Saklatvala J, Vincent T Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis. Arthritis Rheum., 2009-07-01;60(7):2019-27. 2009-07-01 [PMID: 19565481] (In Vivo, Mouse) |
In Vivo |
Mouse |
Nakagomi T, Taguchi A, Fujimori Y, Saino O, Nakano-Doi A, Kubo S, Gotoh A, Soma T, Yoshikawa H, Nishizaki T, Nakagomi N, Stern DM, Matsuyama T Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice. Eur. J. Neurosci., 2009-04-17;29(0):1842-52. 2009-04-17 [PMID: 19473237] (Bioassay, Mouse) |
Bioassay |
Mouse |
Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res., 2009-05-12;69(10):4537-44. 2009-05-12 [PMID: 19435903] (In Vivo, Mouse) |
In Vivo |
Mouse |
Sorg H, Krueger C, Schulz T, Menger MD, Schmitz F, Vollmar B Effects of erythropoietin in skin wound healing are dose related. FASEB J., 2009-04-27;23(9):3049-58. 2009-04-27 [PMID: 19403513] (Bioassay, Mouse) |
Bioassay |
Mouse |
Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth. Cancer Res., 2009-02-17;69(5):2141-8. 2009-02-17 [PMID: 19223532] (In Vivo, Mouse) |
In Vivo |
Mouse |
Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, Ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. J. Neurosci., 2008-12-17;28(51):13978-84. 2008-12-17 [PMID: 19091986] (Bioassay, Mouse) |
Bioassay |
Mouse |
Bai Y, Cui M, Meng Z, Shen L, He Q, Zhang X, Chen F, Xiao J Ectopic expression of angiopoietin-1 promotes neuronal differentiation in neural progenitor cells through the Akt pathway. Biochem. Biophys. Res. Commun., 2008-11-24;378(2):296-301. 2008-11-24 [PMID: 19028450] (Bioassay, Mouse) |
Bioassay |
Mouse |
Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Exp. Cell Res., 2008-08-26;314(18):3292-305. 2008-08-26 [PMID: 18775695] (In Vivo, Mouse) |
In Vivo |
Mouse |
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, Suzuki H, Aizawa S, Arakaki M, Yuasa K, Oka K, Chai Y, Nonaka K, Fukumoto S Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J. Biol. Chem., 2008-06-17;283(34):23139-49. 2008-06-17 [PMID: 18559345] (Bioassay, Mouse) |
Bioassay |
Mouse |
Merchan P, Bribian A, Sanchez-Camacho C, Lezameta M, Bovolenta P, De Castro F Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors. Mol. Cell. Neurosci., 2007-08-01;36(3):355-68. 2007-08-01 [PMID: 17826177] (Bioassay, Mouse) |
Bioassay |
Mouse |
Schwartz B, Shoseyov O, Melnikova VO, McCarty M, Leslie M, Roiz L, Smirnoff P, Hu GF, Lev D, Bar-Eli M ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis. Cancer Res., 2007-06-01;67(11):5258-66. 2007-06-01 [PMID: 17545605] (In Vivo, Mouse) |
In Vivo |
Mouse |
Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, Nye E, Stamp G, Alitalo K, Downward J Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice. Cell, 2007-06-01;129(5):957-68. 2007-06-01 [PMID: 17540175] (Bioassay, Mouse) |
Bioassay |
Mouse |
Chang MY, Sun W, Ochiai W, Nakashima K, Kim SY, Park CH, Kang JS, Shim JW, Jo AY, Kang CS, Lee YS, Kim JS, Lee SH Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells. Mol. Cell. Biol., 2007-04-16;27(12):4293-305. 2007-04-16 [PMID: 17438128] (Bioassay, Mouse) |
Bioassay |
Mouse |
Le Ricousse-Roussanne S, Larghero J, Zini JM, Barateau V, Foubert P, Uzan G, Liu X, Lacassagne MN, Ternaux B, Robert I, Benbunan M, Vilquin JT, Vauchez K, Tobelem G, Marolleau JP Ex vivo generation of mature and functional human smooth muscle cells differentiated from skeletal myoblasts. Exp. Cell Res., 2007-02-08;313(7):1337-46. 2007-02-08 [PMID: 17362928] (In Vivo, Mouse) |
In Vivo |
Mouse |
Gossrau G, Thiele J, Konang R, Schmandt T, Brustle O Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells. Stem Cells, 2007-01-11;25(4):939-49. 2007-01-11 [PMID: 17218404] (Bioassay, Mouse) |
Bioassay |
Mouse |
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