| Cheng, RYS;Ridnour, LA;Wink, AL;Gonzalez, AL;Femino, EL;Rittscher, H;Somasundaram, V;Heinz, WF;Coutinho, L;Rangel, MC;Edmondson, EF;Butcher, D;Kinders, RJ;Li, X;Wong, STC;McVicar, DW;Anderson, SK;Pore, M;Hewitt, SM;Billiar, TR;Glynn, SA;Chang, JC;Lockett, SJ;Ambs, S;Wink, DA; Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome Cell death & disease 2023-05-11 [PMID: 37169743] (Bioassay, Human) |
Bioassay |
Human |
| D Avancini, A Testori, L Fresolone, G Andolfi, M Vuono, V Martinelli, FR Santoni de, S Gregori Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells Cell Reports, 2023-03-03;42(3):112193. 2023-03-03 [PMID: 36870061] (Reference Standard, Human) |
Reference Standard |
Human |
| H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, C Lucas, I Cohen, S Coffey, N Lele, L Greta, K Raddassi, O Chaudhary, A Unterman, B Emu, SH Kleinstein, RR Montgomery, A Iwasaki, CS Dela Cruz, N Kaminski, AC Shaw, DA Hafler, TS Sumida PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection Cell Reports, 2023-01-02;0(0):111895. 2023-01-02 [PMID: 36596303] (Cell Culture, Human) |
Cell Culture |
Human |
| E Turner, L Chen, JG Foulke, Z Gu, F Tian CRISPR/Cas9 Edited RAS & MEK Mutant Cells Acquire BRAF and MEK Inhibitor Resistance with MEK1 Q56P Restoring Sensitivity to MEK/BRAF Inhibitor Combo and KRAS G13D Gaining Sensitivity to Immunotherapy Cancers, 2022-11-05;14(21):. 2022-11-05 [PMID: 36358868] (Bioassay, Human) |
Bioassay |
Human |
| S Hayashi, CK Muraleedha, M Oku, S Tomar, SP Hogan, M Quiros, CA Parkos, A Nusrat Intestinal epithelial BLT1 promotes mucosal repair JCI Insight, 2022-12-08;0(0):. 2022-12-08 [PMID: 36301666] (Bioassay, Human) |
Bioassay |
Human |
| P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease Cell Reports, 2022-09-27;40(13):111439. 2022-09-27 [PMID: 36170836] (Bioassay, Human) |
Bioassay |
Human |
| S Mitra, R Gera, J Sundheimer, M Lemee, LU Wahlberg, B Linderoth, M Eriksdotte, H Behbahani Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimer's Disease Therapy International Journal of Molecular Sciences, 2022-08-12;23(16):. 2022-08-12 [PMID: 36012296] (Bioassay, Human) |
Bioassay |
Human |
| T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119. 2022-08-22 [PMID: 35994674] (Cell Culture, Human) |
Cell Culture |
Human |
| S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge STUB1 is an intracellular checkpoint for interferon gamma sensing Scientific Reports, 2022-08-18;12(1):14087. 2022-08-18 [PMID: 35982220] (Bioassay, Human) |
Bioassay |
Human |
| S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii Nature Communications, 2022-08-08;13(1):4605. 2022-08-08 [PMID: 35941154] (Bioassay, Human) |
Bioassay |
Human |
| Z Zhang, Y Xun, S Rong, L Yan, JA SoRelle, X Li, M Tang, K Keller, S Ludwig, EMY Moresco, B Beutler Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity Nature Communications, 2022-07-16;13(1):4136. 2022-07-16 [PMID: 35842425] (Bioassay, Human) |
Bioassay |
Human |
| S Padmanabha, B Gaire, Y Zou, MM Uddin, I Vancurova IFNgamma-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signaling Cellular Signalling, 2022-07-09;97(0):110400. 2022-07-09 [PMID: 35820543] (Bioassay, Human) |
Bioassay |
Human |
| XJ Mi, JK Kim, S Lee, SK Moon, YJ Kim, H Kim In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals Journal of ethnopharmacology, 2022-07-07;296(0):115523. 2022-07-07 [PMID: 35809756] (Bioassay, Human) |
Bioassay |
Human |
| MD Gundersen, KB Larsen, KM Johnsen, R Goll, J Florholmen, G Haraldsen Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis Scientific Reports, 2022-07-07;12(1):11550. 2022-07-07 [PMID: 35798804] (Bioassay, Human) |
Bioassay |
Human |
| CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells Journal of advanced research, 2021-11-19;39(0):73-88. 2021-11-19 [PMID: 35777918] (Bioassay, Human) |
Bioassay |
Human |
| Y Yoshinaga, T Soma, S Azuma, K Maruyama, Y Hashikawa, T Katayama, Y Sasamoto, H Takayanagi, N Hosen, T Shiina, K Ogasawara, R Hayashi, K Nishida Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets Stem Cell Reports, 2022-06-23;0(0):. 2022-06-23 [PMID: 35750044] (Bioassay, Human) |
Bioassay |
Human |
| E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, S Sinha, M Perry, GA Duncan, MA Scull Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium MBio, 2022-06-14;0(0):e0105522. 2022-06-14 [PMID: 35699372] (Bioassay, Human) |
Bioassay |
Human |
| S Hong, EY Kim, SE Lim, JH Kim, Y Sohn, HS Jung Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells International Journal of Molecular Sciences, 2022-04-18;23(8):. 2022-04-18 [PMID: 35457288] (Bioassay, Human) |
Bioassay |
Human |
| DY Zander, SS Burkart, S Wüst, VG Magalhães, M Binder Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death Cell Death & Disease, 2022-04-18;13(4):364. 2022-04-18 [PMID: 35436994] (Bioassay, Human) |
Bioassay |
Human |
| L Casciola-R, DR Thiemann, F Andrade, MI Trejo-Zamb, EK Leonard, JB Spangler, NE Skinner, J Bailey, S Yegnasubra, R Wang, AM Vaghasia, A Gupta, AL Cox, SC Ray, RM Linville, Z Guo, PC Searson, CE Machamer, S Desiderio, LM Sauer, O Laeyendeck, BT Garibaldi, L Gao, M Damarla, PM Hassoun, JE Hooper, CA Mecoli, L Christophe, L Gutierrez-, Q Yang, D Hines, WA Clarke, RE Rothman, A Pekosz, KZ Fenstermac, Z Wang, SL Zeger, A Rosen IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function JCI Insight, 2022-05-09;7(9):. 2022-05-09 [PMID: 35349483] (Bioassay, Human) |
Bioassay |
Human |
| P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells Cancers, 2022-03-11;14(6):. 2022-03-11 [PMID: 35326601] (Cell Culture, Human) |
Cell Culture |
Human |
| T Schmit, K Guo, JK Tripathi, Z Wang, B McGregor, M Klomp, G Ambigapath, R Mathur, J Hur, M Pichichero, J Kolls, MN Khan Interferon-gamma promotes monocyte-mediated lung injury during influenza infection Cell Reports, 2022-03-01;38(9):110456. 2022-03-01 [PMID: 35235782] (Bioassay, Human) |
Bioassay |
Human |
| A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response Cancer Immunology Research, 2022-04-01;0(0):. 2022-04-01 [PMID: 35181787] (Bioassay, Human) |
Bioassay |
Human |
| J Kim, H Jang, GJ Lee, Y Hur, J Keum, JK Jo, SE Yun, SJ Park, YJ Park, MJ Choi, KS Kim, J Kim A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-gamma-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells Cells, 2021-12-22;11(1):. 2021-12-22 [PMID: 35011581] (Cell Culture, Human) |
Cell Culture |
Human |
| PL Chi, CC Cheng, CC Hung, MT Wang, HY Liu, MW Ke, MC Shen, KC Lin, SH Kuo, PP Hsieh, SR Wann, WC Huang MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension International journal of biological sciences, 2022-01-01;18(1):331-348. 2022-01-01 [PMID: 34975336] (Bioassay, Human) |
Bioassay |
Human |
| Y Cheng, TR Hall, X Xu, I Yung, D Souza, J Zheng, F Schiele, M Hoffmann, ML Mbow, JP Garnett, J Li Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease EBioMedicine, 2021-12-18;75(0):103758. 2021-12-18 [PMID: 34933179] (Bioassay, Human) |
Bioassay |
Human |
| SR Rosenbaum, M Tiago, S Caksa, C Capparelli, TJ Purwin, G Kumar, M Glasheen, D Pomante, D Kotas, I Chervoneva, AE Aplin SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects Cell Reports, 2021-12-07;37(10):110085. 2021-12-07 [PMID: 34879275] (Bioassay, Human) |
Bioassay |
Human |
| A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets Cell Reports, 2021-11-23;37(8):110037. 2021-11-23 [PMID: 34818536] (Bioassay, Human) |
Bioassay |
Human |
| Y Song, G Hou, J Diep, YS Ooi, NS Akopyants, SM Beverley, JE Carette, HB Greenberg, S Ding Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation Nucleic Acids Research, 2021-12-16;0(0):. 2021-12-16 [PMID: 34791430] (Bioassay, Human) |
Bioassay |
Human |
| E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, SH Nam, JW Lee TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment Cell Reports, 2021-11-16;37(7):110018. 2021-11-16 [PMID: 34788612] (Bioassay, Human) |
Bioassay |
Human |
| YH Liang, KH Chen, JH Tsai, YM Cheng, CC Lee, CH Kao, KY Chan, YT Chen, WL Hsu, KH Yeh Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells Journal of Biomedical Science, 2021-11-10;28(1):75. 2021-11-10 [PMID: 34758826] (Bioassay, Human) |
Bioassay |
Human |
| C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling The Journal of Biological Chemistry, 2021-11-03;0(0):101380. 2021-11-03 [PMID: 34740611] (Bioassay, Human) |
Bioassay |
Human |
| S Wüst, P Schad, S Burkart, M Binder Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses Cells, 2021-09-30;10(10):. 2021-09-30 [PMID: 34685580] (Stimulation, Human) |
Stimulation |
Human |
| HJ Lee, HD Kim, CH Jo, EY Bok, SB Kim, SL Lee, M Jang, SG Bae, SH Yun, SJ Kim, GJ Rho, WJ Lee IFN-gamma Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application BioMed Research International, 2021-09-04;2021(0):4604856. 2021-09-04 [PMID: 34527737] (Bioassay, Porcine) |
Bioassay |
Porcine |
| S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris JCI Insight, 2021-10-22;0(0):. 2021-10-22 [PMID: 34491907] (Bioassay, Human) |
Bioassay |
Human |
| N Abu-Shahba, M Mahmoud, AM El-Erian, MI Husseiny, G Nour-Eldee, I Helwa, K Amr, M ElHefnawi, AI Othman, SA Ibrahim, O Azmy Impact of Type 2 Diabetes Mellitus on the Immunoregulatory Characteristics of Adipose Tissue-Derived Mesenchymal Stem Cells The international journal of biochemistry & cell biology, 2021-08-26;0(0):106072. 2021-08-26 [PMID: 34455058] (Bioassay, Human) |
Bioassay |
Human |
| XY Zhu, N Klomjit, SM Conley, MM Ostlie, KL Jordan, A Lerman, LO Lerman Impaired immunomodulatory capacity in adipose tissue-derived mesenchymal stem/stromal cells isolated from obese patients Journal of Cellular and Molecular Medicine, 2021-08-21;0(0):. 2021-08-21 [PMID: 34418300] (Bioassay, Human) |
Bioassay |
Human |
| S Nakajima, K Mimura, T Matsumoto, AK Thar Min, M Ito, H Nakano, P Neupane, Y Kanke, H Okayama, M Saito, T Momma, Y Watanabe, H Hanayama, S Hayase, Z Saze, K Kono The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells Scientific Reports, 2021-08-19;11(1):16891. 2021-08-19 [PMID: 34413454] (Bioassay, Human) |
Bioassay |
Human |
| S Azari, LJ Johnson, A Webb, SM Kozlowski, X Zhang, K Rood, A Amer, S Seveau Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors MBio, 2021-08-17;12(4):e0184921. 2021-08-17 [PMID: 34399615] (Bioassay, Human) |
Bioassay |
Human |
| C Prelli Boz, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, S Heller, CM Stürzel, D Kmiec, C Conzelmann, J Müller, F Zech, E Braun, R Gro beta , L Wettstein, T Weil, J Wei beta , F Diofano, AA Rodríguez, S Wiese, D Sauter, J Münch, C Goffinet, A Catanese, M Schön, TM Boeckers, S Stenger, K Sato, S Just, A Kleger, KMJ Sparrer, F Kirchhoff IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro Nature Communications, 2021-07-28;12(1):4584. 2021-07-28 [PMID: 34321474] (Bioassay, Human) |
Bioassay |
Human |
| S Luostarine, M Hämäläinen, N Hatano, K Muraki, E Moilanen The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells Pulmonary pharmacology & therapeutics, 2021-07-21;70(0):102059. 2021-07-21 [PMID: 34302984] (Bioassay, Human) |
Bioassay |
Human |
| D Lobato-Már, J Xu, GÖ Güler, A Ojiakor, M Pilhofer, S Mostowy Mechanistic insight into bacterial entrapment by septin cage reconstitution Nature Communications, 2021-07-23;12(1):4511. 2021-07-23 [PMID: 34301939] (Bioassay, Human) |
Bioassay |
Human |
| R Luna-Yolba, J Marmoiton, V Gigo, X Marechal, E Boet, A Sahal, N Alet, I Abramovich, E Gottlieb, V Visentin, MR Paillasse, JE Sarry Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells Cancers, 2021-07-13;13(14):. 2021-07-13 [PMID: 34298712] (Bioassay, Human) |
Bioassay |
Human |
| X Yang, X Zhao, Y Zhu, Y Shen, Y Wang, P Lu, Z Jiang, H Pan, J Yang, J Xun, L Zhao, J Wang, Z Liang, X Shen, Y Liang, Q Lin, H Liang, L Jin, D Zhang, J Liu, B Wang, S Jiang, J Xu, H Wu, H Lu, H Zhu FKBP3 Induces Human Immunodeficiency Virus Type 1 Latency by Recruiting Histone Deacetylase 1/2 to the Viral Long Terminal Repeat MBio, 2021-07-20;0(0):e0079521. 2021-07-20 [PMID: 34281390] (Bioassay, Human) |
Bioassay |
Human |
| JS Aguilar Dí, HL Glenn, M Knappenber, CR Borges Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells Journal of Cancer, 2021-06-16;12(16):4993-5004. 2021-06-16 [PMID: 34234868] (ELISA (Capture), Human) |
ELISA (Capture) |
Human |
| H Lee, DH Lee, JH Oh, JH Chung Skullcapflavone II Suppresses TNF-alpha/IFN-gamma-Induced TARC, MDC, and CTSS Production in HaCaT Cells International Journal of Molecular Sciences, 2021-06-16;22(12):. 2021-06-16 [PMID: 34208434] (Bioassay, Human) |
Bioassay |
Human |
| AC Tecalco-Cr, M Macías-Sil, JO Ramírez-Ja, B Méndez-Amb Identification of genes modulated by interferon gamma in breast cancer cells Biochemistry and Biophysics Reports, 2021-06-16;27(0):101053. 2021-06-16 [PMID: 34189281] (Cell Culture, Human) |
Cell Culture |
Human |
| SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer Nature Communications, 2021-06-03;12(1):3299. 2021-06-03 [PMID: 34083537] (Bioassay, Human) |
Bioassay |
Human |
| MC Suárez-Arr, A Méndez-Ten, V Pérez-Kold, EM Fuentes-Pa Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity Cancers, 2021-05-07;13(9):. 2021-05-07 [PMID: 34067089] (Bioassay, Human) |
Bioassay |
Human |
| T Seime, AC Akbulut, ML Liljeqvist, A Siika, H Jin, G Winski, RH van Gorp, E Karlöf, M Lengquist, AJ Buckler, M Kronqvist, OJ Waring, JHN Lindeman, EAL Biessen, L Maegdefess, A Razuvaev, LJ Schurgers, U Hedin, L Matic Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification Cells, 2021-05-21;10(6):. 2021-05-21 [PMID: 34063989] (Bioassay, Human) |
Bioassay |
Human |
| J Pettmann, A Huhn, E Abu Shah, MA Kutuzov, DB Wilson, ML Dustin, SJ Davis, PA van der Me, O Dushek The discriminatory power of the T cell receptor Elife, 2021-05-25;10(0):. 2021-05-25 [PMID: 34030769] (Bioassay, Human) |
Bioassay |
Human |
| YH Liang, JH Tsai, YM Cheng, KY Chan, WL Hsu, CC Lee, KH Chen, KH Yeh Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing Scientific Reports, 2021-04-27;11(1):9080. 2021-04-27 [PMID: 33907276] (Bioassay, Human) |
Bioassay |
Human |
| BY Wang, YY Ye, C Qian, HB Zhang, HX Mao, LP Yao, X Sun, GH Lu, SZ Zhang Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease Neural regeneration research, 2021-12-01;16(12):2521-2527. 2021-12-01 [PMID: 33907043] (Bioassay, Human) |
Bioassay |
Human |
| Bsat M, Mehta H, Rubio M, Sarfati M The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages. Curr Protoc, 2021-03-01;1(3):e74. 2021-03-01 [PMID: 33705607] (Bioassay, Human) |
Bioassay |
Human |
| L Jerby-Arno, C Neftel, ME Shore, HR Weisman, ND Mathewson, MJ McBride, B Haas, B Izar, A Volorio, G Boulay, L Cironi, AR Richman, LC Broye, JM Gurski, CC Luo, R Mylvaganam, L Nguyen, S Mei, JC Melms, C Georgescu, O Cohen, JE Buendia-Bu, A Segerstolp, M Sud, MS Cuoco, D Labes, S Gritsch, DR Zollinger, N Ortogero, JM Beechem, G Petur Niel, I Chebib, T Nguyen-Ngo, M Montemurro, GM Cote, E Choy, I Letovanec, S Cherix, N Wagle, PK Sorger, AB Haynes, JT Mullen, I Stamenkovi, MN Rivera, C Kadoch, KW Wucherpfen, O Rozenblatt, ML Suvà, N Riggi, A Regev Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma Nature Medicine, 2021-01-25;0(0):. 2021-01-25 [PMID: 33495604] (Bioassay, Human) |
Bioassay |
Human |
| H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 2021-01-21;11(1):1949. 2021-01-21 [PMID: 33479269] (Bioassay, Human) |
Bioassay |
Human |
| TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes EBioMedicine, 2021-01-12;63(0):103175. 2021-01-12 [PMID: 33450518] (Bioassay, Human) |
Bioassay |
Human |
| Y Wang, M Mohseni, A Grauel, JE Diez, W Guan, S Liang, JE Choi, M Pu, D Chen, T Laszewski, S Schwartz, J Gu, L Mansur, T Burks, L Brodeur, R Velazquez, S Kovats, B Pant, G Buruzula, E Deng, JT Chen, F Sari-Sarra, C Dornelas, M Varadaraja, H Yu, C Liu, J Lim, HX Hao, X Jiang, A Malamas, MJ LaMarche, FC Geyer, M McLaughlin, C Costa, J Wagner, D Ruddy, P Jayaraman, ND Kirkpatric, P Zhang, O Iartchouk, K Aardalen, V Cremasco, G Dranoff, JA Engelman, S Silver, H Wang, WD Hastings, S Goldoni SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms Scientific Reports, 2021-01-14;11(1):1399. 2021-01-14 [PMID: 33446805] (Bioassay, Human) |
Bioassay |
Human |
| C Li, H Yao, H Wang, JY Fang, J Xu Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity Oncogene, 2020-12-15;0(0):. 2020-12-15 [PMID: 33323966] (Cell Culture, Human) |
Cell Culture |
Human |
| R Abreu, L Essler, P Giri, F Quinn Interferon-gamma promotes iron export in human macrophages to limit intracellular bacterial replication PLoS ONE, 2020-12-08;15(12):e0240949. 2020-12-08 [PMID: 33290416] (Cell Culture, Human) |
Cell Culture |
Human |
| ZZ Bai, HY Li, CH Li, CL Sheng, XN Zhao M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-&kappaB Signaling Pathway Nanoscale research letters, 2020-12-02;15(1):221. 2020-12-02 [PMID: 33263825] (Human) |
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Human |
| X Li, G Yin, W Ji, J Liu, Y Zhang, J Wang, X Zhu, L Zhu, D Dai, W Ma, W Xu 18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model Onco Targets Ther, 2020-11-13;13(0):11659-11668. 2020-11-13 [PMID: 33223839] (Cell Culture, Human) |
Cell Culture |
Human |
| V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells Nat Commun, 2020-10-14;11(1):5163. 2020-10-14 [PMID: 33057020] (Bioassay, Human) |
Bioassay |
Human |
| J Bhushan, JB Radke, YC Perng, M Mcallaster, DJ Lenschow, HW Virgin, LD Sibley ISG15 Connects Autophagy and IFN-&gamma-Dependent Control of Toxoplasma gondii Infection in Human Cells MBio, 2020-10-06;11(5):. 2020-10-06 [PMID: 33024031] (Cell Culture, Human) |
Cell Culture |
Human |
| EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation PLoS ONE, 2020-10-06;15(10):e0240319. 2020-10-06 [PMID: 33021986] (Cell Culture, Human) |
Cell Culture |
Human |
| T Nicotra, A Desnos, J Halimi, H Antonot, L Reppel, T Belmas, A Freton, F Stranieri, M Mebarki, J Larghero, A Cras, L Faivre Mesenchymal stem/stromal cell quality control: validation of mixed lymphocyte reaction assay using flow cytometry according to ICH Q2(R1) Stem Cell Res Ther, 2020-10-01;11(1):426. 2020-10-01 [PMID: 33004063] (Cell Culture, Human) |
Cell Culture |
Human |
| B Cioni, A Zaalberg, JR van Beijnu, MHM Melis, J van Burgst, MJ Muraro, E Hooijberg, D Peters, I Hofland, Y Lubeck, J de Jong, J Sanders, J Vivié, HG van der Po, JP de Boer, AW Griffioen, W Zwart, AM Bergman Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion Nat Commun, 2020-09-09;11(1):4498. 2020-09-09 [PMID: 32908142] (Bioassay, Human) |
Bioassay |
Human |
| A Yakimovich, M Huttunen, J Samolej, B Clough, N Yoshida, S Mostowy, EM Frickel, J Mercer Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection mSphere, 2020-09-09;5(5):. 2020-09-09 [PMID: 32907956] (Bioassay, Human) |
Bioassay |
Human |
| S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia Cells, 2020-08-31;9(9):. 2020-08-31 [PMID: 32878300] (Bioassay, Human) |
Bioassay |
Human |
| E Abu-Shah, N Trendel, P Kruger, J Nguyen, J Pettmann, M Kutuzov, O Dushek Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses J. Immunol., 2020-08-17;0(0):. 2020-08-17 [PMID: 32817332] (Bioassay, Human) |
Bioassay |
Human |
| TC Huang, HL Wu, SH Chen, YT Wang, CC Wu Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching J Neuroinflammation, 2020-08-14;17(1):240. 2020-08-14 [PMID: 32799887] (Cell Culture, Human) |
Cell Culture |
Human |
| D Fisch, B Clough, MC Domart, V Encheva, H Bando, AP Snijders, LM Collinson, M Yamamoto, AR Shenoy, EM Frickel Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death Cell Rep, 2020-08-11;32(6):108008. 2020-08-11 [PMID: 32783936] (Bioassay, Human) |
Bioassay |
Human |
| A Gustafsson, Z Prgomet, S Jankovskaj, T Ruzgas, J Engblom, L Ohlsson, A Gjörloff W Effect of IFN-gamma on the kynurenine/tryptophan ratio in monolayer-cultured keratinocytes and a 3D reconstructed human epidermis model J. Dermatol. Sci., 2020-07-17;0(0):. 2020-07-17 [PMID: 32782183] (Bioassay, Human) |
Bioassay |
Human |
| JF Marchini, A Manica, P Crestani, J Dutzmann, EJ Folco, H Weber, P Libby, K Croce Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles J Am Heart Assoc, 2020-07-31;9(15):e015878. 2020-07-31 [PMID: 32750308] (Bioassay, Human) |
Bioassay |
Human |
| SA Tarasov, EA Gorbunov, ES Don, AG Emelyanova, AL Kovalchuk, N Yanamala, AS S Schleker, J Klein-Seet, R Groenestei, JP Tafani, P van der Me, OI Epstein Insights into the Mechanism of Action of Highly Diluted Biologics J. Immunol., 2020-07-29;0(0):. 2020-07-29 [PMID: 32727888] (Bioassay, Human) |
Bioassay |
Human |
| NC Leite, E Sintov, TB Meissner, MA Brehm, DL Greiner, DM Harlan, DA Melton Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells Cell Rep, 2020-07-14;32(2):107894. 2020-07-14 [PMID: 32668238] (Bioassay, Human) |
Bioassay |
Human |
| MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES) Biomed J, 2020-05-29;0(0):. 2020-05-29 [PMID: 32651134] (Bioassay, Human) |
Bioassay |
Human |
| H El-Kehdy, M Najar, J De Kock, DM Agha, V Rogiers, M Merimi, L Lagneaux, EM Sokal, M Najimi Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells Cells, 2020-07-08;9(7):. 2020-07-08 [PMID: 32650454] (Cell Culture, Human) |
Cell Culture |
Human |
| C Su, ME Johnson, A Torres, RM Thomas, E Manduchi, P Sharma, P Mehra, C Le Coz, ME Leonard, S Lu, KM Hodge, A Chesi, J Pippin, N Romberg, SFA Grant, AD Wells Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells Nat Commun, 2020-07-03;11(1):3294. 2020-07-03 [PMID: 32620744] (Cell Culture, Human) |
Cell Culture |
Human |
| J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation Cell Rep, 2020-06-30;31(13):107820. 2020-06-30 [PMID: 32610123] (Bioassay, Human) |
Bioassay |
Human |
| AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, MJ Mlodzianos, LW Whitehead, D Frank, SE Garnish, C Fitzgibbon, A Hempel, SN Young, AV Jacobsen, W Cawthorne, EJ Petrie, MC Faux, K Shield-Art, N Lalaoui, JM Hildebrand, J Silke, KL Rogers, G Lessene, ED Hawkins, JM Murphy MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis Nat Commun, 2020-06-19;11(1):3151. 2020-06-19 [PMID: 32561730] (Bioassay, Human) |
Bioassay |
Human |
| J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang, C Feng, T Gao, Y Chen, Y Li, Z Wang, J Wen, S Yang, P Liu, L Wang, Y Wang, L Peng, GN Stacey, Z Hu, G Feng, W Li, Y Huo, R Jin, N Shyh-Chang, Q Zhou, L Wang, B Hu, H Dai, J Hao Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis Cell Res., 2020-06-16;0(0):. 2020-06-16 [PMID: 32546764] (Bioassay, Human) |
Bioassay |
Human |
| MC Cavé, S Maillard, K Hildenbran, C Mamelonet, MJ Feige, O Devergne Glycosaminoglycans bind human IL-27 and regulate its activity Eur. J. Immunol., 2020-07-02;0(0):. 2020-07-02 [PMID: 32483835] (Bioassay, Human) |
Bioassay |
Human |
| K Shan, N Feng, J Cui, S Wang, H Qu, G Fu, J Li, H Chen, X Wang, R Wang, Y Qi, Z Gu, YQ Chen Resolvin D1 and D2 inhibit tumour growth and inflammation via modulating macrophage polarization J. Cell. Mol. Med., 2020-05-29;0(0):. 2020-05-29 [PMID: 32469149] (Bioassay, Human) |
Bioassay |
Human |
| J Liu, S Xavy, S Mihardja, S Chen, K Sompalli, D Feng, TS Choi, B Agoram, R Majeti, IL Weissman, JP Volkmer Targeting macrophage checkpoint inhibitor SIRPa for anticancer therapy JCI Insight, 2020-06-18;0(0):. 2020-06-18 [PMID: 32427583] (Bioassay, Human) |
Bioassay |
Human |
| YD Kim, SM Park, HC Ha, AR Lee, H Won, H Cha, S Cho, JM Cho HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment J Cancer, 2020-04-06;11(14):4059-4072. 2020-04-06 [PMID: 32368288] (Bioassay, Human) |
Bioassay |
Human |
| H Ray-Jones, K Duffus, A McGovern, P Martin, C Shi, J Hankinson, O Gough, A Yarwood, AP Morris, A Adamson, C Taylor, J Ding, VP Gaddi, Y Fu, P Gaffney, G Orozco, RB Warren, S Eyre Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31 BMC Biol., 2020-05-04;18(1):47. 2020-05-04 [PMID: 32366252] (Cell Culture, Human) |
Cell Culture |
Human |
| MN Dehno, Y Li, H Weiher, IGH Schmidt-Wo Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer Int J Mol Sci, 2020-04-27;21(9):. 2020-04-27 [PMID: 32349280] (Cell Culture, Human) |
Cell Culture |
Human |
| AM Kell, EA Hemann, JB Turnbull, M Gale RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit�Hantaan orthohantavirus replication PLoS Pathog., 2020-04-24;16(4):e1008483. 2020-04-24 [PMID: 32330200] (Cell Culture, Human) |
Cell Culture |
Human |
| D Zhu, TK Johnson, Y Wang, M Thomas, K Huynh, Q Yang, VC Bond, YE Chen, D Liu Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb Stem Cell Res Ther, 2020-04-22;11(1):162. 2020-04-22 [PMID: 32321589] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Nikonova, M Khaitov, DJ Jackson, S Traub, MB Trujillo-T, DA Kudlay, AS Dvornikov, A Del-Rosari, R Valenta, LA Stanciu, R Khaitov, SL Johnston M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations EBioMedicine, 2020-04-09;54(0):102734. 2020-04-09 [PMID: 32279057] (Cell Culture, Human) |
Cell Culture |
Human |
| K Das Gupta, MR Shakespear, JEB Curson, AMV Murthy, A Iyer, MP Hodson, D Ramnath, VA Tillu, JB von Pein, RC Reid, K Tunny, DM Hohenhaus, SV Moradi, GM Kelly, T Kobayashi, JH Gunter, AJ Stevenson, W Xu, L Luo, A Jones, WA Johnston, A Blumenthal, K Alexandrov, BM Collins, JL Stow, DP Fairlie, MJ Sweet Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2 Cell Rep, 2020-02-25;30(8):2712-2728.e8. 2020-02-25 [PMID: 32101747] (Cell Culture, Mouse) |
Cell Culture |
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| B ?y?y?ska-G, B Trzaskowsk, M Dutkiewicz, O Zegrocka-S, M Machci?ska, K Bocian, M Kowalewska, K Koziak The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor Sci Rep, 2020-02-19;10(1):2886. 2020-02-19 [PMID: 32076052] (Cell Culture, Human) |
Cell Culture |
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| K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells BMC Cancer, 2020-01-08;20(1):25. 2020-01-08 [PMID: 31914969] (Cell Culture, Human) |
Cell Culture |
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| ML Amin, D Mawad, S Dokos, P Koshy, PJ Martens, CC Sorrell Immunomodulatory properties of photopolymerizable fucoidan and carrageenans Carbohydr Polym, 2019-11-28;230(0):115691. 2019-11-28 [PMID: 31887956] (Bioassay, Human) |
Bioassay |
Human |
| D Deli?, K Wolk, R Schmid, O Gabrielyan, D Christou, K Rieber, M Rolser, I Jakob, F Wiech, M Griesser, C Wohnhaas, G Kokolakis, E Witte-Händ, P Baum, R Sabat Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients J. Dermatol. Sci., 2019-11-30;0(0):. 2019-11-30 [PMID: 31843230] (Bioassay, Human) |
Bioassay |
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| A Stumpf, T Brandstett, J Hübner, J Rühe Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum PLoS ONE, 2019-12-02;14(12):e0225525. 2019-12-02 [PMID: 31790441] (ELISA Standard, Human) |
ELISA Standard |
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| LA Callender, EC Carroll, EA Bober, AN Akbar, E Solito, SM Henson Mitochondrial mass governs the extent of human T cell senescence Aging Cell, 2019-12-02;0(0):e13067. 2019-12-02 [PMID: 31788930] (Bioassay, Human) |
Bioassay |
Human |
| E Biros, CS Moran Mini tryptophanyl-tRNA synthetase is required for a synthetic phenotype in vascular smooth muscle cells induced by IFN-?-mediated beta2-adrenoceptor signaling Cytokine, 2019-11-28;127(0):154940. 2019-11-28 [PMID: 31786502] (Cell Culture, Human) |
Cell Culture |
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| SM Huang, CS Wu, MH Chiu, CH Wu, YT Chang, GS Chen, CE Lan High glucose environment induces M1 macrophage polarization that impairs keratinocyte migration via TNF-alpha: An important mechanism to delay the diabetic wound healing J. Dermatol. Sci., 2019-11-13;0(0):. 2019-11-13 [PMID: 31761388] (Cell Culture, Human) |
Cell Culture |
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| W Nowak, LN Grendas, LM Sanmarco, IG Estecho, ÁR Arena, N Eberhardt, DE Rodante, MP Aoki, FM Daray, EA Carrera Si, AE Errasti Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR EBioMedicine, 2019-11-18;0(0):. 2019-11-18 [PMID: 31753725] (Cell Culture, Human) |
Cell Culture |
Human |
| N Berges, MS Nawaz, T Børresdatt, L Hagen, M Bjørås, JK Laerdahl, I Alseth Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform PLoS ONE, 2019-11-08;14(11):e0225081. 2019-11-08 [PMID: 31703097] (Cell Culture, Human) |
Cell Culture |
Human |
| WB Hamilton, Y Mosesson, RS Monteiro, KB Emdal, TE Knudsen, C Francavill, N Barkai, JV Olsen, JM Brickman Dynamic lineage priming is driven via direct enhancer regulation by ERK Nature, 2019-11-06;575(7782):355-360. 2019-11-06 [PMID: 31695196] (Cell Culture, Human) |
Cell Culture |
Human |
| KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, CH Yang, LM Pfeffer, N Sohl, R Gangaraju TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation Stem Cell Res Ther, 2019-11-05;10(1):318. 2019-11-05 [PMID: 31690344] (Cell Culture, Human) |
Cell Culture |
Human |
| LNS Andrade, AH Otake, SGB Cardim, FI da Silva, MM Ikoma Saka, TK Furuya, M Uno, FS Pasini, R Chammas Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy Sci Rep, 2019-10-09;9(1):14482. 2019-10-09 [PMID: 31597943] (Cell Culture, Human) |
Cell Culture |
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| C Merriman, D Fu Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress J. Biol. Chem., 2019-10-07;0(0):. 2019-10-07 [PMID: 31591269] (Bioassay, Human) |
Bioassay |
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| Y Wu, MM Konaté, J Lu, H Makhlouf, R Chuaqui, S Antony, JL Meitzler, MJ Difilippan, H Liu, A Juhasz, G Jiang, I Dahan, K Roy, JH Doroshow IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells J. Immunol., 2019-09-23;0(0):. 2019-09-23 [PMID: 31548328] (Bioassay, Human) |
Bioassay |
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| C Ménard, J Dulong, D Roulois, B Hébraud, L Verdière, C Pangault, V Sibut, I Bezier, N Bescher, C Monvoisin, M Gadelorge, N Bertheuil, E Flécher, L Casteilla, P Collas, L Sensebé, P Bourin, N Espagnolle, K Tarte Integrated Transcriptomic, Phenotypic, and Functional Study Reveals Tissue-Specific Immune Properties of Mesenchymal Stromal Cells Stem Cells, 2019-09-10;0(0):. 2019-09-10 [PMID: 31502731] (Bioassay, Human) |
Bioassay |
Human |
| KJ Pahk, CH Shin, IY Bae, Y Yang, SH Kim, K Pahk, H Kim, SJ Oh Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers Sci Rep, 2019-06-21;9(1):9050. 2019-06-21 [PMID: 31227775] (Bioassay, Human) |
Bioassay |
Human |
| M Pascual-Ga, E Bonfill-Te, E Planas-Rig, C Rubio-Pere, R Iurlaro, A Arias, I Cuartas, A Sala-Hojma, L Escudero, F Martínez-R, I Huber-Ruan, P Nuciforo, L Pedrosa, C Marques, I Braña, E Garralda, M Vieito, M Squatrito, E Pineda, F Graus, C Espejo, J Sahuquillo, J Tabernero, J Seoane LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy Nat Commun, 2019-06-11;10(1):2416. 2019-06-11 [PMID: 31186412] (Bioassay, Human) |
Bioassay |
Human |
| CH Yu, B Suh, I Shin, EH Kim, D Kim, YJ Shin, SY Chang, SH Baek, H Kim, ON Bae Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation Int J Mol Sci, 2019-05-28;20(11):. 2019-05-28 [PMID: 31141897] (Bioassay, Human) |
Bioassay |
Human |
| SM Ferrari, F Ragusa, SR Paparo, F Nasini, M Nardi, SS Franceschi, P Fallahi, A Antonelli Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy Autoimmun Rev, 2019-05-04;0(0):. 2019-05-04 [PMID: 31059842] (Bioassay, Human) |
Bioassay |
Human |
| A Ruiz, S Guzmán-Bel, LE Carreto-Bi, Y Gonzalez, E Juárez DNA from virulent M. tuberculosis induces TNF-? production and autophagy in M1 polarized macrophages Microb. Pathog., 2019-05-02;0(0):. 2019-05-02 [PMID: 31054870] (Bioassay, Human) |
Bioassay |
Human |
| S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 2019-05-13;0(0):. 2019-05-13 [PMID: 31002437] (Bioassay, Human) |
Bioassay |
Human |
| AT Dang, RM Teles, PT Liu, A Choi, A Legaspi, EN Sarno, MT Ochoa, K Parvatiyar, G Cheng, M Gilliet, BR Bloom, RL Modlin Autophagy links antimicrobial activity with antigen presentation in Langerhans cells JCI Insight, 2019-04-18;4(8):. 2019-04-18 [PMID: 30996142] (Bioassay, Human) |
Bioassay |
Human |
| JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis J Immunol Res, 2019-02-06;2019(0):1529189. 2019-02-06 [PMID: 30882002] (Bioassay, Human) |
Bioassay |
Human |
| M Ashizawa, H Okayama, T Ishigame, AK Thar Min, K Saito, D Ujiie, Y Murakami, T Kikuchi, Y Nakayama, M Noda, T Tada, H Endo, S Fujita, W Sakamoto, M Saito, Z Saze, T Momma, S Ohki, K Mimura, K Kono microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L1 Mol. Cancer Res., 2019-03-14;0(0):. 2019-03-14 [PMID: 30872332] (Bioassay, Human) |
Bioassay |
Human |
| N Roper, S Gao, TK Maity, AR Banday, X Zhang, A Venugopala, CM Cultraro, R Patidar, S Sindiri, AL Brown, A Goncearenc, AR Panchenko, R Biswas, A Thomas, A Rajan, CA Carter, DE Kleiner, SM Hewitt, J Khan, L Prokunina-, U Guha APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors Cell Rep, 2019-03-05;26(10):2651-2666.e6. 2019-03-05 [PMID: 30840888] (Bioassay, Human) |
Bioassay |
Human |
| M Kita, Y Ano, A Inoue, J Aoki Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells Sci Rep, 2019-02-28;9(1):3135. 2019-02-28 [PMID: 30816271] (Bioassay, Human) |
Bioassay |
Human |
| F Feng, J Zhao, P Li, R Li, L Chen, C Sun Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells Viruses, 2019-02-13;11(2):. 2019-02-13 [PMID: 30781810] (Bioassay, Human) |
Bioassay |
Human |
| K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye Int J Mol Sci, 2019-02-16;20(4):. 2019-02-16 [PMID: 30781494] (Bioassay, Human) |
Bioassay |
Human |
| BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis Sci Rep, 2019-02-04;9(1):1149. 2019-02-04 [PMID: 30718719] (Bioassay, Human) |
Bioassay |
Human |
| T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS Cancer Res., 2019-02-01;0(0):. 2019-02-01 [PMID: 30709930] (Bioassay, Human) |
Bioassay |
Human |
| K Gettler, M Giri, E Kenigsberg, J Martin, LS Chuang, NY Hsu, LA Denson, JS Hyams, A Griffiths, JD Noe, WV Crandall, DR Mack, R Kellermaye, C Abraham, G Hoffman, S Kugathasan, JH Cho Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets Genes Immun., 2019-01-29;0(0):. 2019-01-29 [PMID: 30692607] (Bioassay, Human) |
Bioassay |
Human |
| WY Lei, SC Hsiung, SH Wen, CH Hsieh, CL Chen, CG Wallace, CC Chang, SK Liao Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines J Immunol Res, 2018-12-16;2018(0):8363265. 2018-12-16 [PMID: 30648121] (Bioassay, Human) |
Bioassay |
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| SE Jin, H Ha, HK Shin, CS Seo Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes Molecules, 2019-01-11;24(2):. 2019-01-11 [PMID: 30642008] (Bioassay, Human) |
Bioassay |
Human |
| S Bai, T Chen, X Deng Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells Stem Cells Int, 2018-11-28;2018(0):6082956. 2018-11-28 [PMID: 30622567] (Bioassay, Human) |
Bioassay |
Human |
| ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, NM Savage, PJ Buckhaults, HC Morse, K Liu Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis Cell Rep, 2018-12-11;25(11):3036-3046.e6. 2018-12-11 [PMID: 30540937] (Bioassay, Human) |
Bioassay |
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| E Cruz-Ramos, M Macías-Sil, A Sandoval-H, AC Tecalco-Cr Non-muscle myosin IIA is post-translationally modified by interferon-stimulated gene 15 in breast cancer cells Int. J. Biochem. Cell Biol., 2018-12-05;107(0):14-26. 2018-12-05 [PMID: 30529400] (Bioassay, Human) |
Bioassay |
Human |
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Bioassay |
Human |
| M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence Cell. Physiol. Biochem., 2018-11-26;51(3):1103-1118. 2018-11-26 [PMID: 30476917] (Bioassay, Human) |
Bioassay |
Human |
| S Tomi?, N Ili?, V Kokol, A Gruden-Mov, D Mihajlovi?, M Beki?, L Sofroni?-M, M ?oli?, D Vu?evi? Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells Int J Nanomedicine, 2018-10-31;13(0):6941-6960. 2018-10-31 [PMID: 30464452] (Bioassay, Human) |
Bioassay |
Human |
| S Muntaka, Y Almuhanna, D Jackson, S Singh, A Afryie-Asa, M Cámara, L Martínez-P IFN-? and IL-17A differentially influence the response of human macrophages and neutrophils to Pseudomonas aeruginosa infection Infect. Immun., 2019-01-24;0(0):. 2019-01-24 [PMID: 30455194] (Bioassay, Human) |
Bioassay |
Human |
| DA Bejarano, MC Puertas, K Börner, J Martinez-P, B Müller, HG Kräusslich Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages Viruses, 2018-11-10;10(11):. 2018-11-10 [PMID: 30423802] (Bioassay, Human) |
Bioassay |
Human |
| K Vaeteewoot, R Kariya, P Pothipan, S Fujikawa, C Pairojkul, S Waraasawap, K Kuwahara, C Wongkham, S Wongkham, S Okada Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis Transl Oncol, 2018-11-09;12(2):217-225. 2018-11-09 [PMID: 30415063] (Bioassay, Human) |
Bioassay |
Human |
| HK Park, M Kim, M Sung, SE Lee, YJ Kim, YL Choi Status of programmed death-ligand 1 expression in sarcomas J Transl Med, 2018-11-06;16(1):303. 2018-11-06 [PMID: 30400799] (Bioassay, Human) |
Bioassay |
Human |
| J Zhou, X Li, X Wu, T Zhang, Q Zhu, X Wang, H Wang, K Wang, Y Lin, X Wang Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer Cancer Immunol Res, 2018-11-05;0(0):. 2018-11-05 [PMID: 30396909] (Bioassay, Human) |
Bioassay |
Human |
| K Mulati, J Hamanishi, N Matsumura, K Chamoto, N Mise, K Abiko, T Baba, K Yamaguchi, N Horikawa, R Murakami, M Taki, K Budiman, X Zeng, Y Hosoe, M Azuma, I Konishi, M Mandai VISTA expressed in tumour cells regulates T cell function Br. J. Cancer, 2018-11-09;0(0):. 2018-11-09 [PMID: 30382166] (Bioassay, Human) |
Bioassay |
Human |
| L Mercurio, M Morelli, C Scarponi, EZ Eisenmesse, N Doti, G Pagnanelli, E Gubinelli, C Mazzanti, A Cavani, M Ruvo, CA Dinarello, C Albanesi, S Madonna IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment Cell Death Dis, 2018-10-30;9(11):1104. 2018-10-30 [PMID: 30377293] (Bioassay, Human) |
Bioassay |
Human |
| T Yang, W Zhang, L Wang, C Xiao, L Wang, Y Gong, D Huang, B Guo, Q Li, Y Xiang, Y Nan Co-culture of dendritic cells and cytokine-induced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system BMC Cancer, 2018-10-16;18(1):984. 2018-10-16 [PMID: 30326865] (Bioassay, Human) |
Bioassay |
Human |
| J Hrdý, K Vlasáková, V ?erný, L Súkeníková, O Novotná, P Petrásková, K Boráková, R Lodinová-Ž, L Kolá?ová, L Prokešová Decreased allergy incidence in children supplemented with E. coli O83:K24:H31 and its possible modes of action Eur. J. Immunol., 2018-10-21;0(0):. 2018-10-21 [PMID: 30306557] (Human) |
|
Human |
| TJ Bussian, A Aziz, CF Meyer, BL Swenson, JM van Deurse, DJ Baker Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline Nature, 2018-09-19;0(0):. 2018-09-19 [PMID: 30232451] (Bioassay, Mouse) |
Bioassay |
Mouse |
| ED Anderson, I Sastalla, NJ Earland, M Mahnaz, IN Moore, F Otaizo-Car, TG Myers, CA Myles, SK Datta, IA Myles Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632 PLoS ONE, 2018-09-12;13(9):e0198862. 2018-09-12 [PMID: 30208113] (Bioassay, Human) |
Bioassay |
Human |
| M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-? Physiol Rep, 2018-08-01;6(16):e13831. 2018-08-01 [PMID: 30136410] (Bioassay, Human) |
Bioassay |
Human |
| Y Zou, MM Uddin, S Padmanabha, Y Zhu, P Bu, A Vancura, I Vancurova The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells J. Biol. Chem., 2018-08-22;0(0):. 2018-08-22 [PMID: 30135206] (Bioassay, Human) |
Bioassay |
Human |
| NM Plugis, N Weng, Q Zhao, BA Palanski, HT Maecker, A Habtezion, C Khosla Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin Proc. Natl. Acad. Sci. U.S.A., 2018-08-13;0(0):. 2018-08-13 [PMID: 30104382] (Bioassay, Human) |
Bioassay |
Human |
| SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes Sci Rep, 2018-08-06;8(1):11720. 2018-08-06 [PMID: 30082828] (Bioassay, Human) |
Bioassay |
Human |
| MA Terkawi, R Takano, K Kato Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes J Immunol Res, 2018-07-05;2018(0):6709424. 2018-07-05 [PMID: 30069491] (Bioassay, Human) |
Bioassay |
Human |
| CH Lu, DW Yeh, CY Lai, YL Liu, LR Huang, AY Lee, SC Jin, TH Chuang USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation Oncogene, 2018-07-23;0(0):. 2018-07-23 [PMID: 30038267] (Bioassay, Human) |
Bioassay |
Human |
| I Cañadas, R Thummalapa, JW Kim, S Kitajima, RW Jenkins, CL Christense, M Campisi, Y Kuang, Y Zhang, E Gjini, G Zhang, T Tian, DR Sen, D Miao, Y Imamura, T Thai, B Piel, H Terai, AR Aref, T Hagan, S Koyama, M Watanabe, H Baba, AE Adeni, CA Lydon, P Tamayo, Z Wei, M Herlyn, TU Barbie, R Uppaluri, LM Sholl, E Sicinska, J Sands, S Rodig, KK Wong, CP Paweletz, H Watanabe, DA Barbie Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses Nat. Med., 2018-07-23;0(0):. 2018-07-23 [PMID: 30038220] (Bioassay, Human) |
Bioassay |
Human |
| G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels Proton irradiation orchestrates macrophage reprogramming through NF?B signaling Cell Death Dis, 2018-06-27;9(7):728. 2018-06-27 [PMID: 29950610] (Bioassay, Human) |
Bioassay |
Human |
| S Nakagawa, S Serada, R Kakubari, K Hiramatsu, T Sugase, S Matsuzaki, S Matsuzaki, Y Ueda, K Yoshino, T Ohkawara, M Fujimoto, T Kishimoto, T Kimura, T Naka Intratumoral delivery of an adenoviral vector carrying the SOCS-1 gene enhances T cell-mediated anti-tumor immunity by suppressing PD-L1 Mol. Cancer Ther., 2018-06-11;0(0):. 2018-06-11 [PMID: 29891489] (Bioassay, Human) |
Bioassay |
Human |
| JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation Cell Death Dis, 2018-06-04;9(6):665. 2018-06-04 [PMID: 29867198] (Bioassay, Human) |
Bioassay |
Human |
| KC Osum, AL Burrack, T Martinov, NL Sahli, JS Mitchell, CG Tucker, KE Pauken, K Papas, B Appakalai, JA Spanier, BT Fife Interferon-gamma drives programmed death-ligand 1 expression on islet ? cells to limit T cell function during autoimmune diabetes Sci Rep, 2018-05-29;8(1):8295. 2018-05-29 [PMID: 29844327] (Bioassay, Human) |
Bioassay |
Human |
| LCD Smyth, J Rustenhove, TI Park, P Schweder, D Jansson, PA Heppner, SJ O'Carroll, EW Mee, RLM Faull, M Curtis, M Dragunow Unique and shared inflammatory profiles of human brain endothelia and pericytes J Neuroinflammation, 2018-05-11;15(1):138. 2018-05-11 [PMID: 29751771] (Bioassay, Human) |
Bioassay |
Human |
| E Vorkapic, A Kunath, D Wågsäter Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms Mol Med Rep, 2018-04-27;0(0):. 2018-04-27 [PMID: 29749489] (Bioassay, Human) |
Bioassay |
Human |
| W Vermi, A Micheletti, G Finotti, C Tecchio, F Calzetti, S Costa, M Bugatti, S Calza, C Agostinell, S Pileri, P Balzarini, A Tucci, G Rossi, L Furlani, G Todeschini, A Zamò, F Facchetti, L Lorenzi, S Lonardi, MA Cassatella slan+ monocytes and macrophages mediate CD20-dependent B cell lymphoma elimination via ADCC and ADCP Cancer Res., 2018-05-10;0(0):. 2018-05-10 [PMID: 29748373] (Bioassay, Human) |
Bioassay |
Human |
| AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli Respir. Res., 2018-05-10;19(1):91. 2018-05-10 [PMID: 29747634] (Bioassay, Human) |
Bioassay |
Human |
| S McGarrity, Ó Anuforo, H Halldórsso, A Bergmann, S Halldórsso, S Palsson, HH Henriksen, PI Johansson, Ó Rolfsson Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification Sci Rep, 2018-05-01;8(1):6811. 2018-05-01 [PMID: 29717213] (Bioassay, Human) |
Bioassay |
Human |
| I Pop?na, A ?bols, L Saul?te, K Pleiko, E Zandberga, K J?kabsons, E Endzeli?š, A Llorente, A Lin?, U Rieksti?a Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages Cell Commun. Signal, 2018-04-24;16(1):17. 2018-04-24 [PMID: 29690889] (Differentiation, Differentiation, Human) |
Differentiation, Differentiation |
Human |
| RB Nahomi, S Sampathkum, AM Myers, L Elghazi, DG Smith, J Tang, CA Lee, TS Kern, RH Nagaraj, PE Fort The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2042-2053. 2018-04-01 [PMID: 29677366] (Bioassay, Human) |
Bioassay |
Human |
| C Lema, RY Reins, RL Redfern High-Mobility Group Box 1 in Dry Eye Inflammation Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1741-1750. 2018-04-01 [PMID: 29610858] (Bioassay, Human) |
Bioassay |
Human |
| S Sugita, K Makabe, Y Iwasaki, S Fujii, M Takahashi Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1719-1731. 2018-04-01 [PMID: 29610856] (Bioassay, Human) |
Bioassay |
Human |
| DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 2018-09-01;0(0):. 2018-09-01 [PMID: 29596569] (Bioassay, Human) |
Bioassay |
Human |
| EY Huang, JC Chang, HH Chen, CY Hsu, HC Hsu, KL Wu Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages BMC Cancer, 2018-03-27;18(1):321. 2018-03-27 [PMID: 29580202] (Bioassay, Human) |
Bioassay |
Human |
| D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus Sci Rep, 2018-03-23;8(1):5126. 2018-03-23 [PMID: 29572460] (Bioassay, Human) |
Bioassay |
Human |
| F Huang, B Wang, J Zeng, S Sang, J Lei, Y Lu MicroRNA-374b inhibits liver cancer progression via down regulating programmed cell death-1 expression on cytokine-induced killer cells Oncol Lett, 2018-02-05;15(4):4797-4804. 2018-02-05 [PMID: 29552119] (Bioassay, Human) |
Bioassay |
Human |
| L Huang, S Malu, JA McKenzie, MC Andrews, AH Talukder, T Tieu, TV Karpinets, C Haymaker, MA Forget, LJ Williams, Z Wang, R Mbofung, ZQ Wang, RE Davis, RS Lo, JA Wargo, MA Davies, C Bernatchez, TP Heffernan, RN Amaria, A Korkut, W Peng, J Roszik, G Lizee, SE Woodman, P Hwu The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A�expression Clin. Cancer Res., 2018-03-01;0(0):. 2018-03-01 [PMID: 29496759] (Bioassay, Human) |
Bioassay |
Human |
| MW Tang, B Malvar Fer, SP Newsom, JD van Buul, TRDJ Radstake, DL Baeten, PP Tak, KA Reedquist, S García Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes Rheumatology (Oxford), 2018-05-01;0(0):. 2018-05-01 [PMID: 29471421] (Differentiation, Differentiation, Human) |
Differentiation, Differentiation |
Human |
| N Singh, P Kansal, Z Ahmad, N Baid, H Kushwaha, N Khatri, A Kumar Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy is dependent on the HMOX1 (heme oxygenase 1)-mediated increase in the intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis Autophagy, 2018-05-10;0(0):1-57. 2018-05-10 [PMID: 29457983] (Bioassay, Mouse) |
Bioassay |
Mouse |
| A Palazzo, S Herter, L Grosmaire, R Jones, CR Frey, F Limani, M Bacac, P Umana, RJ Oldham, MJE Marshall, KL Cox, AH Turaj, MS Cragg, C Klein, MJ Carter, S Tannheimer The PI3K?-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo J. Immunol., 2018-02-16;0(0):. 2018-02-16 [PMID: 29453281] (Bioassay, Human) |
Bioassay |
Human |
| AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes Diabetologia, 2018-02-14;0(0):. 2018-02-14 [PMID: 29445851] (Cell Culture, Human, Mouse) |
Cell Culture |
Human, Mouse |
| TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee Changes in the Anti-Allergic Activities of Sesame by Bioconversion Nutrients, 2018-02-14;10(2):. 2018-02-14 [PMID: 29443928] (Bioassay, Human) |
Bioassay |
Human |
| CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, LC Chan, T Kim, SS Chang, HH Lee, CK Chou, YL Liu, HC Yeh, EP Perillo, AK Dunn, CW Kuo, KH Khoo, JL Hsu, Y Wu, JM Hsu, H Yamaguchi, TH Huang, AA Sahin, GN Hortobagyi, SS Yoo, MC Hung Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1 Cancer Cell, 2018-02-12;33(2):187-201.e10. 2018-02-12 [PMID: 29438695] (Bioassay, Human) |
Bioassay |
Human |
| WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature Front Immunol, 2018-01-29;9(0):80. 2018-01-29 [PMID: 29434599] (Cell Culture, Human) |
Cell Culture |
Human |
| T Oth, THPM Habets, WTV Germeraad, MI Zonneveld, GMJ Bos, J Vanderloch Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-? BMC Immunol., 2018-02-13;19(1):8. 2018-02-13 [PMID: 29433450] (Bioassay, Human) |
Bioassay |
Human |
| N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4 Front Immunol, 2018-01-24;9(0):11. 2018-01-24 [PMID: 29416536] (Bioassay, Human) |
Bioassay |
Human |
| M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann Virus-like infection induces human ? cell dedifferentiation JCI Insight, 2018-02-08;3(3):. 2018-02-08 [PMID: 29415896] (Bioassay, Human) |
Bioassay |
Human |
| C Breuker, C Amouzou, O Fabre, K Lambert, P Seyer, A Bourret, T Salehzada, J Mercier, A Sultan, C Bisbal Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women Metab. Clin. Exp., 2018-02-02;0(0):. 2018-02-02 [PMID: 29410345] (Cell Culture, Human) |
Cell Culture |
Human |
| X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells J Cancer, 2018-01-01;9(2):367-374. 2018-01-01 [PMID: 29344283] (Bioassay, Human) |
Bioassay |
Human |
| TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock J Innate Immun, 2018-01-16;0(0):. 2018-01-16 [PMID: 29334679] (Bioassay, Human) |
Bioassay |
Human |
| Y Sun, J Jiang, P Tien, W Liu, J Li INF-?: A new spotlight in innate immunity against influenza virus infection Protein Cell, 2018-10-01;0(0):. 2018-10-01 [PMID: 29332267] (Bioassay, Human) |
Bioassay |
Human |
| R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis Cardiovasc Diabetol, 2017-11-06;16(1):143. 2017-11-06 [PMID: 29110715] (Bioassay, Human) |
Bioassay |
Human |
| RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, M Bowden, J Deng, H Liu, D Miao, MX He, W Walker, G Zhang, T Tian, C Cheng, Z Wei, S Palakurthi, M Bittinger, H Vitzthum, JW Kim, A Merlino, M Quinn, C Venkataram, JA Kaplan, A Portell, PC Gokhale, B Phillips, A Smart, A Rotem, RE Jones, L Keogh, M Anguiano, L Stapleton, Z Jia, M Barzily-Ro, I Cañadas, TC Thai, MR Hammond, R Vlahos, ES Wang, H Zhang, S Li, GJ Hanna, W Huang, MP Hoang, A Piris, JP Eliane, AO Stemmer-Ra, L Cameron, MJ Su, P Shah, B Izar, M Thakuria, NR LeBoeuf, G Rabinowits, V Gunda, S Parangi, JM Cleary, BC Miller, S Kitajima, R Thummalapa, B Miao, TU Barbie, V Sivathanu, J Wong, WG Richards, R Bueno, CH Yoon, J Miret, M Herlyn, LA Garraway, EM Van Allen, GJ Freeman, PT Kirschmeie, JH Lorch, PA Ott, FS Hodi, KT Flaherty, RD Kamm, GM Boland, KK Wong, D Dornan, CP Paweletz, DA Barbie Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids Cancer Discov, 2017-11-03;0(0):. 2017-11-03 [PMID: 29101162] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
| A Basu, N Jain, BS Tolbert, AA Komar, B Mazumder Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon Nucleic Acids Res., 2017-12-15;0(0):. 2017-12-15 [PMID: 29069516] (Bioassay, Human) |
Bioassay |
Human |
| NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis Sci Rep, 2017-10-23;7(1):13831. 2017-10-23 [PMID: 29062018] (Bioassay, Human) |
Bioassay |
Human |
| F Liu, Q Niu, X Fan, C Liu, J Zhang, Z Wei, W Hou, TD Kanneganti, ML Robb, JH Kim, NL Michael, J Sun, L Soong, H Hu Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor J. Immunol., 2017-09-25;0(0):. 2017-09-25 [PMID: 28947539] (Bioassay, Human) |
Bioassay |
Human |
| Y Qin, M Li, SL Zhou, W Yin, Z Bian, HB Shu SPI-2/CrmA inhibits IFN-? induction by targeting TBK1/IKK? Sci Rep, 2017-09-05;7(1):10495. 2017-09-05 [PMID: 28874755] (Bioassay, Human) |
Bioassay |
Human |
| N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency Sci Rep, 2017-08-15;7(1):8153. 2017-08-15 [PMID: 28811575] (Bioassay, Human) |
Bioassay |
Human |
| MW Tang, S Garcia, B Malvar Fer, DM Gerlag, PP Tak, KA Reedquist Rheumatoid arthritis and psoriatic arthritis synovial fluid stimulates prolactin production by macrophages J. Leukoc. Biol., 2017-06-22;0(0):. 2017-06-22 [PMID: 28642278] (Bioassay, Human) |
Bioassay |
Human |
| JD Widdringto, A Gomez-Dura, JS Steyn, A Pyle, MH Ruchaud-Sp, J Scott, SV Baudouin, AJ Rostron, J Simpson, PF Chinnery F Mitochondrial DNA depletion induces innate immune dysfunction rescued by interferon-? J. Allergy Clin. Immunol., 2017-06-17;0(0):. 2017-06-17 [PMID: 28629747] (Bioassay, Human) |
Bioassay |
Human |
| HM Rostam, PM Reynolds, MR Alexander, N Gadegaard, AM Ghaemmagha Image based Machine Learning for identification of macrophage subsets Sci Rep, 2017-06-14;7(1):3521. 2017-06-14 [PMID: 28615717] (Bioassay, Human) |
Bioassay |
Human |
| A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors JCI Insight, 2017-06-15;2(12):. 2017-06-15 [PMID: 28614795] (Bioassay, Human) |
Bioassay |
Human |
| Q Wu, A Allouch, A Paoletti, C Leteur, C Mirjolet, I Martins, L Voisin, F Law, H Dakhli, E Mintet, M Thoreau, Z Muradova, M Gauthier, O Caron, F Milliat, DM Ojcius, F Rosselli, E Solary, N Modjtahedi, E Deutsch, JL Perfettini NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy Cell Death Differ., 2017-06-02;0(0):. 2017-06-02 [PMID: 28574504] (Bioassay, Human) |
Bioassay |
Human |
| JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma Mol. Cancer Ther., 2017-06-01;0(0):. 2017-06-01 [PMID: 28572167] (Bioassay, Human) |
Bioassay |
Human |
| F Arruda-Sil, F Bianchetto, S Gasperini, S Polletti, E Cosentino, N Tamassia, MA Cassatella Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNF? Front Cell Infect Microbiol, 2017-05-12;7(0):176. 2017-05-12 [PMID: 28553619] (Bioassay, Human) |
Bioassay |
Human |
| N Hakimzadeh, J Elias, GWM Wijntjens, R Theunissen, A van Weert, MW Smulders, N van den Ak, PD Moerland, HJ Verberne, LP Hoebers, JPS Henriques, AM van der La, M Ilhan, M Post, SCAM Bekkers, JJ Piek Monocytic microRNA profile associated with coronary collateral artery function in chronic total occlusion patients Sci Rep, 2017-05-08;7(1):1532. 2017-05-08 [PMID: 28484274] (Bioassay, Human) |
Bioassay |
Human |
| X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions J Extracell Vesicles, 2017-04-21;6(1):1314073. 2017-04-21 [PMID: 28473886] (Bioassay, Human) |
Bioassay |
Human |
| E El Darzi, S Bazzi, S Daoud, KS Echtay, GM Bahr Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-?, interleukin-4, tumor necrosis factor-?, or muramyl dipeptide Int J Immunopathol Pharmacol, 2017-04-28;0(0):3946320177076. 2017-04-28 [PMID: 28449603] (Bioassay, Human) |
Bioassay |
Human |
| E Nagy, Y Lei, E Martínez-M, SC Body, F Schlotter, M Creager, A Assmann, K Khabbaz, P Libby, GK Hansson, E Aikawa Interferon-? Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves Am. J. Pathol., 2017-04-19;0(0):. 2017-04-19 [PMID: 28431214] (Bioassay, Human) |
Bioassay |
Human |
| Y Arai, D Takahashi, K Asano, M Tanaka, M Oda, SBH Ko, MSH Ko, S Mandai, N Nomura, T Rai, S Uchida, E Sohara Salt suppresses IFN? inducible chemokines through the IFN?-JAK1-STAT1 signaling pathway in proximal tubular cells Sci Rep, 2017-04-20;7(0):46580. 2017-04-20 [PMID: 28425456] (Bioassay, Human) |
Bioassay |
Human |
| E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro Stem Cell Res Ther, 2017-04-17;8(1):79. 2017-04-17 [PMID: 28412968] (Bioassay, Human) |
Bioassay |
Human |
| A Raimondo, S Lembo, RD Caprio, G Donnarumma, G Monfrecola, N Balato, F Ayala, A Balato Psoriatic cutaneous inflammation promotes human monocyte differentiation into active osteoclasts, facilitating bone damage Eur. J. Immunol., 2017-05-02;0(0):. 2017-05-02 [PMID: 28386999] (Bioassay, Human) |
Bioassay |
Human |
| L Tian, A Goldstein, H Wang, H Ching Lo, I Sun Kim, T Welte, K Sheng, LE Dobrolecki, X Zhang, N Putluri, TL Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, WK Decker, C Zong, MT Lewis, XH Zhang Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming Nature, 2017-04-03;0(0):. 2017-04-03 [PMID: 28371798] (Bioassay, Human) |
Bioassay |
Human |
| JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36? Proc. Natl. Acad. Sci. U.S.A, 2017-03-13;114(13):E2748-E2757. 2017-03-13 [PMID: 28289191] (Bioassay, Human) |
Bioassay |
Human |
| AC Tecalco Cr, K Mejía-Barr Cell type-dependent regulation of free ISG15 levels and ISGylation J Cell Commun Signal, 2017-03-11;0(0):. 2017-03-11 [PMID: 28285335] (Bioassay, Human) |
Bioassay |
Human |
| BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps Allergy, 2017-04-04;0(0):. 2017-04-04 [PMID: 28258963] (Bioassay, Human) |
Bioassay |
Human |
| D Labrousse-, E Martínez-A, M Corral-Esc, R Bienes-Mar, J Berridy, L Serrano-Ov, E Conde, ML García-Ber, JM Giménez-Ba, AS Salinas-Sá, R Sánchez-Pr, M Yao, M Lasa, MJ Calzada VHL promotes immune response against renal cell carcinoma via NF-?B-dependent regulation of VCAM-1 J. Cell Biol, 2017-02-24;0(0):. 2017-02-24 [PMID: 28235946] (Bioassay, Human) |
Bioassay |
Human |
| MA Schumacher, M Hedl, C Abraham, JK Bernard, PR Lozano, JJ Hsieh, D Almohazey, EB Bucar, S Punit, PJ Dempsey, MR Frey ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation Cell Death Dis, 2017-02-23;8(2):e2622. 2017-02-23 [PMID: 28230865] (Bioassay, Human) |
Bioassay |
Human |
| X Zhang, Y Yang, L Zhang, Y Lu, Q Zhang, D Fan, Y Zhang, Y Zhang, Z Ye, D Xiong Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan J Hematol Oncol, 2017-02-23;10(1):56. 2017-02-23 [PMID: 28228105] (Bioassay, Human) |
Bioassay |
Human |
| MH van Atteku, S Terpstra, E Slinger, M von Linder, PD Moerland, A Jongejan, AP Kater, E Eldering Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia Oncogene, 2017-02-13;0(0):. 2017-02-13 [PMID: 28192408] (Bioassay, Human) |
Bioassay |
Human |
| HC Hsia, JE Hutti, AS Baldwin Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity J. Biol. Chem, 2017-02-10;0(0):. 2017-02-10 [PMID: 28188292] (Bioassay, Human) |
Bioassay |
Human |
| MA Terkawi, R Takano, A Furukawa, F Murakoshi, K Kato Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum Sci Rep, 2017-02-09;7(0):41772. 2017-02-09 [PMID: 28181499] (Bioassay, Human) |
Bioassay |
Human |
| A Qin, DH Lai, Q Liu, W Huang, YP Wu, X Chen, S Yan, H Xia, G Hide, ZR Lun, FJ Ayala, AP Xiang Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii Proc. Natl. Acad. Sci. U.S.A, 2017-01-25;0(0):. 2017-01-25 [PMID: 28123064] (Bioassay, Human) |
Bioassay |
Human |
| MJ Bae, S Ryu, HJ Kim, SI Cha, CH Kim, J Lee Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages Tuberc Respir Dis (Seoul), 2016-12-30;80(1):77-82. 2016-12-30 [PMID: 28119750] (Bioassay, Human) |
Bioassay |
Human |
| Y Zhang, Y Kong, S Liu, L Zeng, L Wan, Z Zhang Curcumin induces apoptosis in human leukemic cell lines through an IFIT2-dependent pathway Cancer Biol. Ther, 2017-01-10;0(0):1-8. 2017-01-10 [PMID: 28071969] (Bioassay, Human) |
Bioassay |
Human |
| J Huang, F Shen, H Huang, C Ling, G Zhang Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC Oncotarget, 2017-02-21;8(8):13116-13125. 2017-02-21 [PMID: 28061450] (Bioassay, Human) |
Bioassay |
Human |
| AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin IFN type I and II induce BAFF secretion from human decidual stromal cells Sci Rep, 2017-01-06;7(0):39904. 2017-01-06 [PMID: 28057926] (Bioassay, Human) |
Bioassay |
Human |
| Nicholas M Plugis Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: Implications for Celiac Disease J. Biol. Chem, 2016-12-21;0(0):. 2016-12-21 [PMID: 28003361] (Bioassay, Human) |
Bioassay |
Human |
| Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells PLoS ONE, 2016-12-01;11(12):e0167361. 2016-12-01 [PMID: 27907087] (Bioassay, Human) |
Bioassay |
Human |
| Mark L Chiu Fc engineering approaches to enhance the agonism and effector functions of an anti-OX40 antibody J. Biol. Chem., 2016-11-17;0(0):. 2016-11-17 [PMID: 27856634] (Bioassay, Human) |
Bioassay |
Human |
| Andrea Todisco Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2. 2016-11-17 [PMID: 27856416] (Bioassay, Human) |
Bioassay |
Human |
| Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells Int J Mol Sci, 2016-11-12;17(11):. 2016-11-12 [PMID: 27845745] (Bioassay, Human) |
Bioassay |
Human |
| Robert Sabat MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations Mediators Inflamm., 2016-10-23;2016(0):4097574. 2016-10-23 [PMID: 27843200] (Bioassay, Human) |
Bioassay |
Human |
| Qiyun Zhu Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-? Signaling Pathways by Targeting VISA J. Immunol., 2016-11-07;0(0):. 2016-11-07 [PMID: 27821666] (Bioassay, Human) |
Bioassay |
Human |
| Susheela Tridandapa Interferon-? Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells J. Biol. Chem., 2016-10-25;291(49):25656-25666. 2016-10-25 [PMID: 27780867] (Bioassay, Human) |
Bioassay |
Human |
| Programmed death-ligand 1 (PD-L1) characterization of circulating tumor cells (CTCs) in muscle invasive and metastatic bladder cancer patients BMC Cancer, 2016-09-22;16(1):744. 2016-09-22 [PMID: 27658492] (Bioassay, Human) |
Bioassay |
Human |
| Interferon-? blocks signalling through PDGFR? in human brain pericytes J Neuroinflammation, 2016-09-21;13(1):249. 2016-09-21 [PMID: 27654972] (Bioassay, Human) |
Bioassay |
Human |
| TLR3 preconditioning enhances the therapeutic efficacy of umbilical cord mesenchymal stem cells in TNBS-induced colitis via the TLR3-Jagged-1-Notch-1 pathway Mucosal Immunol, 2016-09-21;0(0):. 2016-09-21 [PMID: 27649928] (Bioassay, Human) |
Bioassay |
Human |
| Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells Elife, 2016-09-20;5(0):. 2016-09-20 [PMID: 27644592] (Bioassay, Human) |
Bioassay |
Human |
| Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic Proc Natl Acad Sci USA, 2016-09-06;113(38):10643-10648. 2016-09-06 [PMID: 27601677] (Bioassay, Human) |
Bioassay |
Human |
| MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA Mol Immunol, 2016-08-16;77(0):205-212. 2016-08-16 [PMID: 27541693] (Bioassay, Human) |
Bioassay |
Human |
| Identification of a major epitope by anti-interferon-? autoantibodies in patients with mycobacterial disease Nat Med, 2016-08-15;0(0):. 2016-08-15 [PMID: 27525523] (Western Blot, Human) |
Western Blot |
Human |
| PD-1/PD-L1 blockade enhances T cell activity and antitumor efficacy of imatinib in gastrointestinal stromal tumors Clin Cancer Res, 2016-07-28;0(0):. 2016-07-28 [PMID: 27470968] (Bioassay, Human) |
Bioassay |
Human |
| Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype Sci Rep, 2016-07-19;6(0):29712. 2016-07-19 [PMID: 27431276] (Bioassay, Human) |
Bioassay |
Human |
| G Karina Chimal-Ram Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes J Immunol Res, 2016-06-08;2016(0):6031486. 2016-06-08 [PMID: 27376091] (Bioassay, Human) |
Bioassay |
Human |
| Martine Schrøder CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits PLoS ONE, 2016-06-16;11(6):e0157387. 2016-06-16 [PMID: 27311059] (Bioassay, Human) |
Bioassay |
Human |
| Takuya Matsumoto Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages Arthritis Res Ther, 2016-06-07;18(1):133. 2016-06-07 [PMID: 27267914] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Kellie N Smith Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells MBio, 2016-05-31;7(3):. 2016-05-31 [PMID: 27247230] (Bioassay, Human) |
Bioassay |
Human |
| M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu, D Ren, B Yu, L Zheng, X Hu, W Shi, J Xu Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis Stem Cell Res Ther, 2016-04-23;7(1):63. 2016-04-23 [PMID: 27107963] (Bioassay, Human) |
Bioassay |
Human |
| SW Jackson, HM Jacobs, T Arkatkar, EM Dam, NE Scharping, NS Kolhatkar, B Hou, JH Buckner, DJ Rawlings B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6 J Exp Med, 2016-04-11;0(0):. 2016-04-11 [PMID: 27069113] (Bioassay, Human) |
Bioassay |
Human |
| Guo Z, Zheng L, Liao X, Geller D Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex. PLoS ONE, 2016-01-11;11(1):e0146640. 2016-01-11 [PMID: 26751080] (Bioassay, Human) |
Bioassay |
Human |
| Maleki Vareki S, Chen D, Di Cresce C, Ferguson P, Figueredo R, Pampillo M, Rytelewski M, Vincent M, Min W, Zheng X, Koropatnick J IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells. PLoS ONE, 2015-11-18;10(11):e0143435. 2015-11-18 [PMID: 26579709] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Nagarsheth N, Peng D, Kryczek I, Wu K, Li W, Zhao E, Zhao L, Wei S, Frankel T, Vatan L, Szeliga W, Dou Y, Owens S, Marquez V, Tao K, Huang E, Wang G, Zou W PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. Cancer Res, 2015-11-13;76(2):275-82. 2015-11-13 [PMID: 26567139] (Bioassay, Human) |
Bioassay |
Human |
| Rhein B, Powers L, Rogers K, Anantpadma M, Singh B, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey R, Monick M, Maury W Interferon-gamma Inhibits Ebola Virus Infection. PLoS Pathog, 2015-11-12;11(11):e1005263. 2015-11-12 [PMID: 26562011] (Bioassay, Human) |
Bioassay |
Human |
| Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? PLoS ONE, 2015-07-21;10(7):e0133392. 2015-07-21 [PMID: 26197437] (Bioassay, Human) |
Bioassay |
Human |
| Howland S, Poh C, Renia L Activated Brain Endothelial Cells Cross-Present Malaria Antigen. PLoS Pathog, 2015-06-05;11(6):e1004963. 2015-06-05 [PMID: 26046849] (Bioassay, Human) |
Bioassay |
Human |
| Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate. Eur J Immunol, 2015-05-28;45(9):2494-503. 2015-05-28 [PMID: 25959978] (Bioassay, Human) |
Bioassay |
Human |
| Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage. PLoS ONE, 2015-05-08;10(5):e0125375. 2015-05-08 [PMID: 25955295] (Bioassay, Human) |
Bioassay |
Human |
| Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE, 2015-05-08;10(5):e0126159. 2015-05-08 [PMID: 25955018] (Bioassay, Human) |
Bioassay |
Human |
| Chiu E, Gold T, Fettig V, LeVasseur M, Cressman D Identification of a nuclear export sequence in the MHC CIITA. J Immunol, 2015-05-06;194(12):6102-11. 2015-05-06 [PMID: 25948812] (Bioassay, Human) |
Bioassay |
Human |
| Folgiero V, Cifaldi L, Li Pira G, Goffredo B, Vinti L, Locatelli F TIM-3/Gal-9 interaction induces IFNgamma-dependent IDO1 expression in acute myeloid leukemia blast cells. J Hematol Oncol, 2015-04-16;8(0):36. 2015-04-16 [PMID: 25886742] (Bioassay, Human) |
Bioassay |
Human |
| Abiko K, Matsumura N, Hamanishi J, Horikawa N, Murakami R, Yamaguchi K, Yoshioka Y, Baba T, Konishi I, Mandai M IFN-gamma from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer. Br J Cancer, 2015-03-31;112(9):1501-9. 2015-03-31 [PMID: 25867264] (Bioassay, Human) |
Bioassay |
Human |
| Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M. Respir Res, 2015-02-07;16(0):14. 2015-02-07 [PMID: 25849622] (Bioassay, Human) |
Bioassay |
Human |
| Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, Seftel M, Lipton J, Gupta V, Humar A, Husain S Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis. PLoS ONE, 2015-04-02;10(4):e0123171. 2015-04-02 [PMID: 25835547] (Bioassay, Human) |
Bioassay |
Human |
| Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Nat Med, 2015-03-16;21(4):363-72. 2015-03-16 [PMID: 25774850] (Bioassay, Human) |
Bioassay |
Human |
| Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences. J Invest Dermatol, 2015-03-04;135(7):1771-80. 2015-03-04 [PMID: 25739051] (Bioassay, Human) |
Bioassay |
Human |
| Singh S, Barr H, Liu Y, Robins A, Heeb S, Williams P, Fogarty A, Camara M, Martinez-Pomares L Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-gamma-treated macrophages to Pseudomonas aeruginosa infection. PLoS ONE, 2015-02-23;10(2):e0117447. 2015-02-23 [PMID: 25706389] (Bioassay, Human) |
Bioassay |
Human |
| Herova M, Schmid M, Gemperle C, Hersberger M ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol, 2015-01-30;194(5):2330-7. 2015-01-30 [PMID: 25637017] (Bioassay, Human) |
Bioassay |
Human |
| Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 2015-01-20;56(2):1051-62. 2015-01-20 [PMID: 25604685] (Bioassay, Human) |
Bioassay |
Human |
| Reiner A, Heldt S, Presley C, Guley N, Elberger A, Deng Y, D'Surney L, Rogers J, Ferrell J, Bu W, Del Mar N, Honig M, Gurley S, Moore B Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189. Int J Mol Sci, 2014-12-31;16(1):758-87. 2014-12-31 [PMID: 25561230] (Bioassay, Human) |
Bioassay |
Human |
| Arnold C, Gordon P, Barker R, Wilson H The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses. Immunobiology, 2015-01-01;220(1):10-9. 2015-01-01 [PMID: 25454489] (Bioassay, Human) |
Bioassay |
Human |
| Kenna T, Lau M, Keith P, Ciccia F, Costello M, Bradbury L, Low P, Agrawal N, Triolo G, Alessandro R, Robinson P, Thomas G, Brown M Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis. Genes Immun, 2014-11-06;16(1):35-42. 2014-11-06 [PMID: 25354578] (Bioassay, Human) |
Bioassay |
Human |
| Oth , Tammy, Schnijderberg , Melanie, Senden-Gijsbers , Birgit L, Germeraad , Wilfred, Bos , Gerard M, Vanderlocht , Joris Monitoring the initiation and kinetics of human dendritic cell-induced polarization of autologous naive CD4+ T cells. PLoS ONE, 2014-08-21;9(8):e103725. 2014-08-21 [PMID: 25144736] (Bioassay, Human) |
Bioassay |
Human |
| Niedbala W, Besnard A, Nascimento D, Donate P, Sonego F, Yip E, Guabiraba R, Chang H, Fukada S, Salmond R, Schmitt E, Bopp T, Ryffel B, Liew F Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nat Commun, 2014-08-07;5(0):4575. 2014-08-07 [PMID: 25099390] (Bioassay, Human) |
Bioassay |
Human |
| Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b. J Immunol, 2014-08-04;193(6):3036-44. 2014-08-04 [PMID: 25092892] |
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| Deng B, Wang C, Arnardottir H, Li Y, Cheng C, Dalli J, Serhan C Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. PLoS ONE, 2014-07-18;9(7):e102362. 2014-07-18 [PMID: 25036362] (Bioassay, Human) |
Bioassay |
Human |
| Berri F, Haffar G, Le V, Sadewasser A, Paki K, Lina B, Wolff T, Riteau B Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication. J Virol, 2014-07-16;88(19):11215-28. 2014-07-16 [PMID: 25031344] (Bioassay, Human) |
Bioassay |
Human |
| Uhlenbrock F, Hagemann-Jensen M, Kehlet S, Andresen L, Pastorekova S, Skov S The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway. J Immunol, 2014-07-14;193(4):1654-65. 2014-07-14 [PMID: 25024379] (Bioassay, Human) |
Bioassay |
Human |
| Jansson D, Rustenhoven J, Feng S, Hurley D, Oldfield R, Bergin P, Mee E, Faull R, Dragunow M A role for human brain pericytes in neuroinflammation. J Neuroinflammation, 2014-06-11;11(0):104. 2014-06-11 [PMID: 24920309] (Bioassay, Human) |
Bioassay |
Human |
| Zhong H, Bao W, Friedman D, Yazdanbakhsh K Hemin controls T cell polarization in sickle cell alloimmunization. J Immunol, 2014-05-30;193(1):102-10. 2014-05-30 [PMID: 24879794] (Bioassay, Human) |
Bioassay |
Human |
| Cichocki F, Schlums H, Li H, Stache V, Holmes T, Lenvik T, Chiang S, Miller J, Meeths M, Anderson S, Bryceson Y Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency. J Exp Med, 2014-05-19;211(6):1079-91. 2014-05-19 [PMID: 24842371] (Bioassay, Human) |
Bioassay |
Human |
| MacLeod A, Rudolph R, Corriden R, Ye I, Garijo O, Havran W Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. J Immunol, 2014-05-07;192(12):5695-702. 2014-05-07 [PMID: 24808367] (Bioassay, Human) |
Bioassay |
Human |
| Shi L, Zhang Z, Yu A, Wang W, Wei Z, Akhter E, Maurer K, Costa Reis P, Song L, Petri M, Sullivan K The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs. PLoS ONE, 2014-05-05;9(5):e93846. 2014-05-05 [PMID: 24796678] (Bioassay, Human) |
Bioassay |
Human |
| Ren Z, Kang W, Wang L, Sun B, Ma J, Zheng C, Sun J, Tian Z, Yang X, Xiao W E2F1 renders prostate cancer cell resistant to ICAM-1 mediated antitumor immunity by NF-kappaB modulation. Mol Cancer, 2014-04-17;13(0):84. 2014-04-17 [PMID: 24742333] (Bioassay, Human) |
Bioassay |
Human |
| Wong , Tina W, Doyle , Alfred D, Lee , James J, Jelinek , Diane F Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol, 2014-03-10;192(8):3548-58. 2014-03-10 [PMID: 24616476] (Bioassay, Human) |
Bioassay |
Human |
| Fairfax B, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight J Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science, 2014-03-07;343(6175):1246949. 2014-03-07 [PMID: 24604202] (Bioassay, Human) |
Bioassay |
Human |
| Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. FASEB J, 2014-03-06;28(6):2551-65. 2014-03-06 [PMID: 24604078] (Bioassay, Human) |
Bioassay |
Human |
| Chiricozzi , Andrea, Nograles , Kristine, Johnson-Huang , Leanne M, Fuentes-Duculan , Judilyn, Cardinale , Irma, Bonifacio , Kathleen, Gulati , Nicholas, Mitsui , Hiroshi, Guttman-Yassky , Emma, Suarez-Farinas , Mayte, Krueger , James G IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model. PLoS ONE, 2014-02-28;9(2):e90284. 2014-02-28 [PMID: 24587313] (Bioassay, Human) |
Bioassay |
Human |
| Jebran A, Schleicher U, Steiner R, Wentker P, Mahfuz F, Stahl H, Amin F, Bogdan C, Stahl K Rapid healing of cutaneous leishmaniasis by high-frequency electrocauterization and hydrogel wound care with or without DAC N-055: a randomized controlled phase IIa trial in Kabul. PLoS Negl Trop Dis, 2014-02-13;8(2):e2694. 2014-02-13 [PMID: 24551257] (Bioassay, Human) |
Bioassay |
Human |
| Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure. PLoS ONE, 2014-02-14;9(2):e88714. 2014-02-14 [PMID: 24551140] (Bioassay, Human) |
Bioassay |
Human |
| Valle Oseguera , Cendy A, Spencer , Juliet V cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells. PLoS ONE, 2014-02-10;9(2):e88708. 2014-02-10 [PMID: 24520416] (Bioassay, Human) |
Bioassay |
Human |
| Voraphani N, Gladwin M, Contreras A, Kaminski N, Tedrow J, Milosevic J, Bleecker E, Meyers D, Ray A, Ray P, Erzurum S, Busse W, Zhao J, Trudeau J, Wenzel S An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. Mucosal Immunol, 2014-02-12;7(5):1175-85. 2014-02-12 [PMID: 24518246] (Bioassay, Human) |
Bioassay |
Human |
| Culina S, Mauvais F, Hsu H, Burgevin A, Guenette S, Moser A, van Endert P No major role for insulin-degrading enzyme in antigen presentation by MHC molecules. PLoS ONE, 2014-02-07;9(2):e88365. 2014-02-07 [PMID: 24516642] (Bioassay, Human) |
Bioassay |
Human |
| Melhem N, Smith K, Huang X, Colleton B, Jiang W, Mailliard R, Mullins J, Rinaldo C The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8(+) T cell responses. Virology, 2013-12-20;450(0):34-48. 2013-12-20 [PMID: 24503065] (Bioassay, Human) |
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Human |
| Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis. J Immunol, 2014-02-05;192(5):2449-59. 2014-02-05 [PMID: 24501201] (Bioassay, Human) |
Bioassay |
Human |
| Italiani , Paola, Mazza , Emilia M, Lucchesi , Davide, Cifola , Ingrid, Gemelli , Claudia, Grande , Alexis, Battaglia , Cristina, Bicciato , Silvio, Boraschi , Diana Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS ONE, 2014-02-03;9(2):e87680. 2014-02-03 [PMID: 24498352] (Bioassay, Human) |
Bioassay |
Human |
| Milwid , Jack M, Elman , Jessica, Li , Matthew, Shen , Keyue, Manrai , Arjun, Gabow , Aaron, Yarmush , Joshua, Jiao , Yunxin, Fletcher , Anne, Lee , Jungwoo, Cima , Michael, Yarmush , Martin L, Parekkadan , Biju Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators. Mol Ther, 2014-02-05;22(5):999-1007. 2014-02-05 [PMID: 24496384] (Bioassay, Human) |
Bioassay |
Human |
| Yamashita A, Zhao Y, Matsuura Y, Yamasaki K, Moriguchi-Goto S, Sugita C, Iwakiri T, Okuyama N, Koshimoto C, Kawai K, Tamaki N, Zhao S, Kuge Y, Asada Y Increased metabolite levels of glycolysis and pentose phosphate pathway in rabbit atherosclerotic arteries and hypoxic macrophage. PLoS ONE, 2014-01-23;9(1):e86426. 2014-01-23 [PMID: 24466087] (Bioassay, Human) |
Bioassay |
Human |
| van Wilgenburg , Bonnie, Moore , Michael, James , William, Cowley , Sally A The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. PLoS ONE, 2014-01-22;9(1):e86071. 2014-01-22 [PMID: 24465876] (Bioassay, Human) |
Bioassay |
Human |
| Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3. Proc Natl Acad Sci U S A, 2014-01-13;111(4):1509-14. 2014-01-13 [PMID: 24434549] (Bioassay, Human) |
Bioassay |
Human |
| Frazier T, McLachlan J, Gimble J, Tucker H, Rowan B Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions. Stem Cells Dev, 2014-03-11;23(9):968-77. 2014-03-11 [PMID: 24405386] (Bioassay, Human) |
Bioassay |
Human |
| Garcia S, Krausz S, Ambarus C, Fernandez B, Hartkamp L, van Es I, Hamann J, Baeten D, Tak P, Reedquist K Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype. PLoS ONE, 2014-01-03;9(1):e82088. 2014-01-03 [PMID: 24404127] (Bioassay, Human) |
Bioassay |
Human |
| Fryer , Ryan M, Ng , Khing Jo, Nodop Mazurek , Suzanne, Patnaude , Lori, Skow , Donna J, Muthukumarana , Akalushi, Gilpin , Kyle E, Dinallo , Roger M, Kuzmich , Daniel, Lord , John, Sanyal , Sulagna, Yu , Hui, Harcken , Christia, Cerny , Matthew, Hickey , Eugene R, Modis , Louise K G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism. J Pharmacol Exp Ther, 2014-01-07;348(3):421-31. 2014-01-07 [PMID: 24399854] (Bioassay, Human) |
Bioassay |
Human |
| Suzuki , Hitoshi, Raska , Milan, Yamada , Koshi, Moldoveanu , Zina, Julian , Bruce A, Wyatt , Robert J, Tomino , Yasuhiko, Gharavi , Ali G, Novak , Jan Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes. J Biol Chem, 2014-01-07;289(8):5330-9. 2014-01-07 [PMID: 24398680] (Bioassay, Human) |
Bioassay |
Human |
| Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter P, Schakel K, Tamassia N, Cassatella M slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells. Nat Commun, 2014-01-01;5(0):3029. 2014-01-01 [PMID: 24398631] (Bioassay, Human) |
Bioassay |
Human |
| Ji , Jianfei, Judkowski , Valeria, Liu , Gentao, Wang , Hongqian, Bunying , Alcinett, Li , Zhenhua, Xu , Minlin, Bender , James, Pinilla , Clemenci, Yu , John S Identification of novel human leukocyte antigen-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy. Stem Cells Transl Med, 2013-12-27;3(3):356-64. 2013-12-27 [PMID: 24375541] (Bioassay, Human) |
Bioassay |
Human |
| Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. J Immunol, 2013-12-09;192(1):59-72. 2013-12-09 [PMID: 24323580] (Bioassay, Human) |
Bioassay |
Human |
| Engstrom A, Erlandsson A, Delbro D, Wijkander J Conditioned media from macrophages of M1, but not M2 phenotype, inhibit the proliferation of the colon cancer cell lines HT-29 and CACO-2. Int J Oncol, 2013-12-02;44(2):385-92. 2013-12-02 [PMID: 24296981] (Bioassay, Human) |
Bioassay |
Human |
| Roy S, Karmakar M, Pearlman E CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo. J Biol Chem, 2013-11-25;289(2):1174-82. 2013-11-25 [PMID: 24275652] (Bioassay, Human) |
Bioassay |
Human |
| Iachininoto M, Nuzzolo E, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells. Molecules, 2013-08-22;18(9):10132-45. 2013-08-22 [PMID: 23973990] (Bioassay, Human) |
Bioassay |
Human |
| Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Muller I Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation. Eur J Immunol, 2013-07-23;43(10):2741-9. 2013-07-23 [PMID: 23817958] (Bioassay, Human) |
Bioassay |
Human |
| Martin J, Beriou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, Scott C, Mowat A, Cerovic V, Houston S, Leboeuf M, Hubert F, Hemont C, Merad M, Milling S, Josien R Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol, 2013-05-08;7(1):101-13. 2013-05-08 [PMID: 23653115] (Bioassay, Human) |
Bioassay |
Human |
| Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma. PLoS ONE, 2013-04-17;8(4):e61446. 2013-04-17 [PMID: 23613854] (Bioassay, Human) |
Bioassay |
Human |
| Zizzo G, Cohen P IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids. J Immunol, 2013-04-17;190(10):5237-46. 2013-04-17 [PMID: 23596310] (Bioassay, Human) |
Bioassay |
Human |
| Madonna S, Scarponi C, Doti N, Carbone T, Cavani A, Scognamiglio P, Marasco D, Albanesi C Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses. Eur J Immunol, 2013-05-28;43(7):1883-95. 2013-05-28 [PMID: 23592500] (Bioassay, Human) |
Bioassay |
Human |
| Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume M, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease. Immunology, 2013-05-01;139(1):19-29. 2013-05-01 [PMID: 23566200] (Bioassay, Human) |
Bioassay |
Human |
| Melo , Rossana, Paganoti , Guillher, Dvorak , Ann M, Weller , Peter F The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography. PLoS ONE, 2013-03-26;8(3):e59578. 2013-03-26 [PMID: 23555714] (Bioassay, Human) |
Bioassay |
Human |
| Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J Immunol, 2013-03-18;190(8):3959-66. 2013-03-18 [PMID: 23509356] (Bioassay, Human) |
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Human |
| Xia , Chuan, Chen , Yuan-Chu, Gong , Hao, Zeng , Wenbo, Vu , Gia-Phon, Trang , Phong, Lu , Sangwei, Wu , Jianguo, Liu , Fenyong Inhibition of hepatitis B virus gene expression and replication by ribonuclease P. Mol Ther, 2013-03-12;21(5):995-1003. 2013-03-12 [PMID: 23481322] (Bioassay, Human) |
Bioassay |
Human |
| Hambleton , Sophie, Goodbourn , Stephen, Young , Dan F, Dickinson , Paul, Mohamad , Siti M B, Valappil , Manoj, McGovern , Naomi, Cant , Andrew J, Hackett , Scott J, Ghazal , Peter, Morgan , Neil V, Randall , Richard STAT2 deficiency and susceptibility to viral illness in humans. Proc Natl Acad Sci U S A, 2013-02-07;110(8):3053-8. 2013-02-07 [PMID: 23391734] (Bioassay, Human) |
Bioassay |
Human |
| Wang , Jia M, Shi , Lei, Ma , Cheng J, Ji , Xiao J, Ying , Ruo S, Wu , Xiao Y, Wang , Ke S, Li , Guangyu, Moorman , Jonathan, Yao , Zhi Q Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection. J Virol, 2013-02-06;87(8):4372-83. 2013-02-06 [PMID: 23388728] (Bioassay, Human) |
Bioassay |
Human |
| Johnston A, Xing X, Swindell W, Kochkodan J, Riblett M, Nair R, Stuart P, Ding J, Voorhees J, Elder J, Gudjonsson J Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis. Hum Mol Genet, 2013-01-31;22(9):1807-15. 2013-01-31 [PMID: 23376980] (Bioassay, Human) |
Bioassay |
Human |
| Bancerek J, Poss Z, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dolken L, Strobl B, Muller M, Taatjes D, Kovarik P CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response. Immunity, 2013-01-24;38(2):250-62. 2013-01-24 [PMID: 23352233] (Bioassay, Human) |
Bioassay |
Human |
| Katholnig K, Kaltenecker C, Hayakawa H, Rosner M, Lassnig C, Zlabinger G, Gaestel M, Muller M, Hengstschlager M, Horl W, Park J, Saemann M, Weichhart T p38alpha senses environmental stress to control innate immune responses via mechanistic target of rapamycin. J Immunol, 2013-01-11;190(4):1519-27. 2013-01-11 [PMID: 23315073] (Cell Culture, Human) |
Cell Culture |
Human |
| Dong J, Chang H, Ivascu C, Qian Y, Rezai S, Okhrimenko A, Cosmi L, Maggi L, Eckhardt F, Wu P, Sieper J, Alexander T, Annunziato F, Gossen M, Li J, Radbruch A, Thiel A Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes. Eur J Immunol, 2013-03-01;43(3):793-804. 2013-03-01 [PMID: 23255246] (Bioassay, Human) |
Bioassay |
Human |
| Bonanno G, Mariotti A, Procoli A, Folgiero V, Natale D, De Rosa L, Majolino I, Novarese L, Rocci A, Gambella M, Ciciarello M, Scambia G, Palumbo A, Locatelli F, De Cristofaro R, Rutella S Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma. J Transl Med, 2012-12-11;10(0):247. 2012-12-11 [PMID: 23232072] (Bioassay, Human) |
Bioassay |
Human |
| Pennino D, Bhavsar P, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham S, Cavani A, Eyerich K, Chung K, Schmidt-Weber C, Eyerich S IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients. J Allergy Clin Immunol, 2012-11-19;131(2):562-70. 2012-11-19 [PMID: 23174657] (Bioassay, Human) |
Bioassay |
Human |
| Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis. J. Exp. Med., 2012-10-15;209(11):2033-47. 2012-10-15 [PMID: 23071254] (Bioassay, Human) |
Bioassay |
Human |
| Kothari H, Rao L, Vankayalapati R, Pendurthi U Mycobacterium tuberculosis infection and tissue factor expression in macrophages. PLoS ONE, 2012-09-24;7(9):e45700. 2012-09-24 [PMID: 23029190] (Bioassay, Human) |
Bioassay |
Human |
| Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis. Blood, 2012-09-18;120(19):4058-67. 2012-09-18 [PMID: 22990013] (Bioassay, Human) |
Bioassay |
Human |
| Zizzo G, Hilliard B, Monestier M, Cohen P Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction. J Immunol, 2012-08-31;189(7):3508-20. 2012-08-31 [PMID: 22942426] (Bioassay, Human) |
Bioassay |
Human |
| Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells. PLoS ONE, 2012-06-22;7(6):e38721. 2012-06-22 [PMID: 22761699] (Bioassay, Human) |
Bioassay |
Human |
| Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase. J. Biol. Chem., 2012-06-11;287(31):25964-74. 2012-06-11 [PMID: 22689578] (Bioassay, Human) |
Bioassay |
Human |
| Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes. J. Invest. Dermatol., 2012-06-07;132(11):2593-600. 2012-06-07 [PMID: 22673732] (Bioassay, Human) |
Bioassay |
Human |
| CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates. Eur. J. Immunol., 2012-07-04;42(8):2019-30. 2012-07-04 [PMID: 22585548] (Bioassay, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)) |
Bioassay |
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque) |
| Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS ONE, 2012-04-18;7(4):e34965. 2012-04-18 [PMID: 22529962] (Bioassay, Human) |
Bioassay |
Human |
| Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q Expression and regulation of CCL15 by human airway smooth muscle cells. Clin. Exp. Allergy, 2011-11-09;42(1):85-94. 2011-11-09 [PMID: 22092970] (Bioassay, Human) |
Bioassay |
Human |
| Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. Gene Ther, 2011-11-10;19(10):1035-40. 2011-11-10 [PMID: 22071967] (Bioassay, Human) |
Bioassay |
Human |
| Wang R, Jaw JJ, Jaw J, Stutzman NC, Stutzman N, Zou Z, Sun PD Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1. J Leukoc Biol, 2011-11-01;91(2):299-309. 2011-11-01 [PMID: 22045868] (Bioassay, Human) |
Bioassay |
Human |
| Carrier Y, Ma HL, Ramon HE, Napierata L, Small C, O'Toole M, Young DA, Fouser LA, Nickerson-Nutter C, Collins M, Dunussi-Joannopoulos K, Medley QG Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis. J. Invest. Dermatol., 2011-09-01;131(12):2428-37. 2011-09-01 [PMID: 21881584] (Bioassay, Human) |
Bioassay |
Human |
| Von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. J. Immunol., 2011-05-04;186(12):6701-9. 2011-05-04 [PMID: 21543643] (Bioassay, Human) |
Bioassay |
Human |
| Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma. PLoS Pathog., 2011-04-14;7(4):e1002016. 2011-04-14 [PMID: 21533215] (Bioassay, Human) |
Bioassay |
Human |
| Epigenetic modulation enhances the therapeutic effect of anti-IL-13R alpha2 antibody in human mesothelioma xenografts. Clin. Cancer Res., 2011-02-28;17(9):2819-29. 2011-02-28 [PMID: 21357681] (Bioassay, Human) |
Bioassay |
Human |
| Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J. Immunol., 2010-12-17;186(2):1119-30. 2010-12-17 [PMID: 21169547] (Bioassay, Human) |
Bioassay |
Human |
| Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha. J. Biol. Chem., 2010-11-08;286(2):961-75. 2010-11-08 [PMID: 21059659] (Bioassay, Human) |
Bioassay |
Human |
| Ghigo E, Barry AO, Pretat L, Al Moussawi K, Desnues B, Capo C, Kornfeld H, Mege JL IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation. PLoS ONE, 2010-10-21;5(10):e13561. 2010-10-21 [PMID: 21042409] (Bioassay, Human) |
Bioassay |
Human |
| Hasegawa H, Thomas HJ, Schooley K, Born TL Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein. Cytokine, 2011-01-01;53(1):74-83. 2011-01-01 [PMID: 20926308] (Bioassay, Human) |
Bioassay |
Human |
| Zhang G, Wang J, Kelly J B7-h3 augments the inflammatory response and is associated with human sepsis. J. Immunol., 2010-08-09;185(6):3677-84. 2010-08-09 [PMID: 20696859] (Bioassay, Human) |
Bioassay |
Human |
| Ghirelli C, Zollinger R, Soumelis V Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. Blood, 2010-04-09;115(24):5037-40. 2010-04-09 [PMID: 20382843] (Bioassay, Human) |
Bioassay |
Human |
| Gudjonsson JE, Johnston A, Stoll SW Evidence for altered Wnt signaling in psoriatic skin. J. Invest. Dermatol., 2010-04-08;130(7):1849-59. 2010-04-08 [PMID: 20376066] (Bioassay, Human) |
Bioassay |
Human |
| Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. J. Immunol., 2010-03-31;184(9):4880-8. 2010-03-31 [PMID: 20357258] (Bioassay, Human) |
Bioassay |
Human |
| Mengshol JA, Golden-Mason L, Arikawa T A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS ONE, 2010-03-04;5(3):e9504. 2010-03-04 [PMID: 20209097] (Bioassay, Human) |
Bioassay |
Human |
| Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy. Biomaterials, 2010-02-01;31(12):3357-63. 2010-02-01 [PMID: 20117833] (Bioassay, Human) |
Bioassay |
Human |
| Nishida A, Andoh A, Imaeda H, Inatomi O, Shiomi H, Fujiyama Y Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts. Gut, 2009-12-08;59(4):531-41. 2009-12-08 [PMID: 19996325] (Bioassay, Human) |
Bioassay |
Human |
| Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur. J. Immunol., 2009-12-01;39(12):3570-81. 2009-12-01 [PMID: 19830738] (Bioassay, Human) |
Bioassay |
Human |
| Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Mucosal Immunol, 2009-10-07;3(1):40-8. 2009-10-07 [PMID: 19812544] (Bioassay, Human) |
Bioassay |
Human |
| Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W, Sabat R, Wolk K Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun., 2009-10-01;10(8):702-14. 2009-10-01 [PMID: 19798076] (Bioassay, Human) |
Bioassay |
Human |
| Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem, 2009-07-15;284(36):24035-48. 2009-07-15 [PMID: 19605353] (Bioassay, Human) |
Bioassay |
Human |
| Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1. Clin. Immunol., 2009-06-25;133(1):27-44. 2009-06-25 [PMID: 19559654] (Bioassay, Human) |
Bioassay |
Human |
| Nishida A, Andoh A, Inatomi O, Fujiyama Y Interleukin-32 expression in the pancreas. J. Biol. Chem., 2009-04-21;284(26):17868-76. 2009-04-21 [PMID: 19386602] (Bioassay, Human) |
Bioassay |
Human |
| Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 2009-03-02;119(10):1424-32. 2009-03-02 [PMID: 19255340] (Bioassay, Human) |
Bioassay |
Human |
| Hao Q, Wang L, Tang H Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7. 2009-01-28 [PMID: 19176759] (Bioassay, Human) |
Bioassay |
Human |
| MacRedmond R, Singhera GK, Dorscheid DR Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury. Eur. Respir. J., 2009-01-22;33(6):1403-14. 2009-01-22 [PMID: 19164355] (Bioassay, Human) |
Bioassay |
Human |
| Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines. Invest. Ophthalmol. Vis. Sci., 2009-01-17;50(6):2702-9. 2009-01-17 [PMID: 19151401] (Bioassay, Human) |
Bioassay |
Human |
| Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med., 2008-12-29;206(1):249-58. 2008-12-29 [PMID: 19114666] (Bioassay, Human) |
Bioassay |
Human |
| Schwinn N, Vokhminova D, Sucker A, Textor S, Striegel S, Moll I, Nausch N, Tuettenberg J, Steinle A, Cerwenka A, Schadendorf D, Paschen A Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells. Int. J. Cancer, 2009-04-01;124(7):1594-604. 2009-04-01 [PMID: 19089914] (Bioassay, Human) |
Bioassay |
Human |
| Lee WI, Liang FC, Huang JL, Jaing TH, Wang CH, Lin TY, Huang YC, Huang WL, Jou R, Hsieh MY, Chia JH, Wu TL Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease. J. Clin. Immunol., 2008-12-13;29(3):319-29. 2008-12-13 [PMID: 19089604] (Bioassay, Human) |
Bioassay |
Human |
| Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol., 2008-12-03;123(1):179-86. 2008-12-03 [PMID: 19056108] (Bioassay, Human) |
Bioassay |
Human |
| Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells. Clin. Exp. Immunol., 2008-11-26;155(2):266-74. 2008-11-26 [PMID: 19040600] (Bioassay, Human) |
Bioassay |
Human |
| Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation. Clin. Exp. Immunol., 2008-12-01;154(3):384-90. 2008-12-01 [PMID: 19037921] (Bioassay, Human) |
Bioassay |
Human |
| Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism. J. Leukoc. Biol., 2008-11-17;85(2):310-21. 2008-11-17 [PMID: 19015376] (Bioassay, Human) |
Bioassay |
Human |
| Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J. Immunol., 2008-11-15;181(10):7420-7. 2008-11-15 [PMID: 18981165] (Bioassay, Human) |
Bioassay |
Human |
| Rahmoun M, Moles JP, Pedretti N, Mathieu M, Fremaux I, Raison-Peyron N, Lecron JC, Yssel H, Pene J Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. J. Invest. Dermatol., 2008-10-09;129(3):671-81. 2008-10-09 [PMID: 18843289] (Bioassay, Human) |
Bioassay |
Human |
| Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. Int. J. Oncol., 2008-08-01;33(2):297-308. 2008-08-01 [PMID: 18636150] (Bioassay, Human) |
Bioassay |
Human |
| Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. J. Leukoc. Biol., 2008-06-30;84(4):1109-19. 2008-06-30 [PMID: 18591415] (Bioassay, Human) |
Bioassay |
Human |
| Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392. 2008-04-14 [PMID: 18410958] (Bioassay, Human) |
Bioassay |
Human |
| Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur. J. Immunol., 2008-04-01;38(4):1012-23. 2008-04-01 [PMID: 18350544] (Bioassay, Human) |
Bioassay |
Human |
| Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res. Hum. Retroviruses, 2008-03-01;24(3):453-62. 2008-03-01 [PMID: 18327985] (ELISA (Standard)) |
ELISA (Standard) |
|
| Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J. Leukoc. Biol., 2008-02-15;83(5):1181-93. 2008-02-15 [PMID: 18281438] (Bioassay, Human) |
Bioassay |
Human |
| Dambacher J, Beigel F, Zitzmann K, Heeg MH, Goke B, Diepolder HM, Auernhammer CJ, Brand S The role of interleukin-22 in hepatitis C virus infection. Cytokine, 2008-01-11;41(3):209-16. 2008-01-11 [PMID: 18191408] (Bioassay, Human) |
Bioassay |
Human |
| Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q Expression and regulation of CCR1 by airway smooth muscle cells in asthma. J. Immunol., 2008-01-15;180(2):1268-75. 2008-01-15 [PMID: 18178867] (Bioassay, Human) |
Bioassay |
Human |
| Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin. Chem., 2007-11-01;53(11):2010-2. 2007-11-01 [PMID: 18030696] (ELISA (Standard)) |
ELISA (Standard) |
|
| Oates JC, Farrelly LW, Hofbauer AF, Wang W, Gilkeson GS Association of reactive oxygen and nitrogen intermediate and complement levels with apoptosis of peripheral blood mononuclear cells in lupus patients. Arthritis Rheum., 2007-11-01;56(11):3738-47. 2007-11-01 [PMID: 17968874] (Bioassay, Human) |
Bioassay |
Human |
| Parmley LA, Elkins ND, Fini MA, Liu YE, Repine JE, Wright RM Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury. Br. J. Pharmacol., 2007-09-10;152(6):915-29. 2007-09-10 [PMID: 17828290] (In Vivo, Rat) |
In Vivo |
Rat |
| Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration. J. Biol. Chem., 2007-08-24;282(43):31643-55. 2007-08-24 [PMID: 17720976] (Bioassay, Human) |
Bioassay |
Human |
| Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis. J. Neurosci., 2007-08-22;27(34):9032-42. 2007-08-22 [PMID: 17715340] (Bioassay, Human) |
Bioassay |
Human |
| Hajishengallis G, Shakhatreh MA, Wang M, Liang S Complement receptor 3 blockade promotes IL-12-Mediated Clearance of Porphyromonas gingivalis and Negates Its Virulence In Vivo. J. Immunol., 2007-08-15;179(4):2359-67. 2007-08-15 [PMID: 17675497] (Bioassay, Human) |
Bioassay |
Human |
| Kato A, Favoreto S, Avila PC, Schleimer RP TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J. Immunol., 2007-07-15;179(2):1080-7. 2007-07-15 [PMID: 17617600] (Bioassay, Human) |
Bioassay |
Human |
| Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. J. Leukoc. Biol., 2007-07-05;82(4):946-55. 2007-07-05 [PMID: 17615381] (Bioassay, Human) |
Bioassay |
Human |
| Shioya M, Nishida A, Yagi Y, Ogawa A, Tsujikawa T, Kim-Mitsuyama S, Takayanagi A, Shimizu N, Fujiyama Y, Andoh A Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease. Clin. Exp. Immunol., 2007-06-22;149(3):480-6. 2007-06-22 [PMID: 17590175] (Bioassay, Human) |
Bioassay |
Human |
| Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. J. Immunol., 2007-06-15;178(12):8064-72. 2007-06-15 [PMID: 17548644] (Bioassay, Human) |
Bioassay |
Human |
| Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS, 2007;21(10):1263-72. 2007 [PMID: 17545702] (ELISA (Standard), N/A) |
ELISA (Standard) |
N/A |
| Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease. Gut, 2007-04-20;56(9):1257-65. 2007-04-20 [PMID: 17449633] (Bioassay, Human) |
Bioassay |
Human |
| Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood, 2007-02-08;109(10):4272-9. 2007-02-08 [PMID: 17289812] (ELISA (Standard)) |
ELISA (Standard) |
|
| Sa SM, Valdez PA, Wu J The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J. Immunol., 2007-02-15;178(4):2229-40. 2007-02-15 [PMID: 17277128] (Bioassay, Human) |
Bioassay |
Human |
| Kanda N, Watanabe S Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. Endocrinology, 2007-01-25;148(5):2317-25. 2007-01-25 [PMID: 17255201] (Bioassay, Human) |
Bioassay |
Human |
| Dame TM, Orenzoff BL, Palmer LE, Furie MB IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation. J. Immunol., 2007-01-15;178(2):1172-9. 2007-01-15 [PMID: 17202382] (Bioassay, Human) |
Bioassay |
Human |
| Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JZ Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. J. Immunol., 2006-12-15;177(12):8844-50. 2006-12-15 [PMID: 17142787] (Bioassay, Human) |
Bioassay |
Human |
| Zhang Y, Taveggia C, Melendez-Vasquez C, Einheber S, Raine CS, Salzer JL, Brosnan CF, John GR Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J. Neurosci., 2006-11-22;26(47):12174-85. 2006-11-22 [PMID: 17122042] (Bioassay, Human) |
Bioassay |
Human |
| Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med., 2006-11-20;203(12):2763-77. 2006-11-20 [PMID: 17116732] (Bioassay, Human) |
Bioassay |
Human |
| Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes. J. Immunol., 2006-12-01;177(11):7665-72. 2006-12-01 [PMID: 17114436] (Bioassay, Human) |
Bioassay |
Human |
| Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression. J. Endocrinol., 2006-10-01;191(1):65-81. 2006-10-01 [PMID: 17065390] (Bioassay, Hamster) |
Bioassay |
Hamster |
| Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, Yagi J, Dianzani U ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells. Eur. J. Immunol., 2006-10-01;36(10):2601-12. 2006-10-01 [PMID: 17013990] (Bioassay, Human) |
Bioassay |
Human |
| Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway. J. Cell. Physiol., 2007-01-01;210(1):192-200. 2007-01-01 [PMID: 17013806] (Bioassay, Human) |
Bioassay |
Human |
| Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia, 2006-11-01;54(6):619-29. 2006-11-01 [PMID: 16944452] (Bioassay, Human) |
Bioassay |
Human |
| Ebert EC, Mehta V Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell. Immunol., 2006-08-17;241(1):7-13. 2006-08-17 [PMID: 16914126] (Bioassay, Human) |
Bioassay |
Human |
| Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 2006-06-16;120(2):220-31. 2006-06-16 [PMID: 16782408] (ELISA (Standard)) |
ELISA (Standard) |
|
| Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol., 2006-05-01;36(5):1309-23. 2006-05-01 [PMID: 16619290] (Bioassay, Human) |
Bioassay |
Human |
| Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood, 2006-04-13;108(3):947-55. 2006-04-13 [PMID: 16614246] (Bioassay, Human) |
Bioassay |
Human |
| Cho ML, Min SY, Chang SH, Kim KW, Heo SB, Lee SH, Park SH, Cho CS, Kim HY Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression. Immunol. Lett., 2006-03-03;105(2):159-66. 2006-03-03 [PMID: 16564576] (Bioassay, Human) |
Bioassay |
Human |
| Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J. Virol., 2005-10-01;79(20):12828-39. 2005-10-01 [PMID: 16188985] (Bioassay, Primate - Chlorocebus pygerythrus (Vervet Monkey)) |
Bioassay |
Primate - Chlorocebus pygerythrus (Vervet Monkey) |
| Ameredes BT, Calhoun WJ Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72. 2005-07-01 [PMID: 15990776] (Bioassay, Human) |
Bioassay |
Human |
| Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. Crit. Care Med., 2005-06-01;33(6):1359-64. 2005-06-01 [PMID: 15942356] (Bioassay, Human) |
Bioassay |
Human |
| Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 2005-05-01;52(5):1504-16. 2005-05-01 [PMID: 15880822] (Bioassay, Human) |
Bioassay |
Human |
| Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum., 2005-03-01;52(3):770-8. 2005-03-01 [PMID: 15751070] (Bioassay, Human) |
Bioassay |
Human |
| Radstake TR, Roelofs MF, Jenniskens YM, van Riel PL, Barrera P Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma. Arthritis Rheum., 2004-12-01;50(12):3856-65. 2004-12-01 [PMID: 15593217] (Bioassay, Human) |
Bioassay |
Human |
| Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med., 2004-11-22;200(11):1419-26. 2004-11-22 [PMID: 15557347] (Bioassay, Human) |
Bioassay |
Human |
| Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. J. Immunol., 2004-11-01;173(9):5810-7. 2004-11-01 [PMID: 15494534] (Bioassay, Human) |
Bioassay |
Human |
| Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood, 2004-09-09;105(2):830-7. 2004-09-09 [PMID: 15358625] (Bioassay, Human) |
Bioassay |
Human |
| Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human) |
Bioassay |
Human |
| Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Bioassay, Human) |
Bioassay |
Human |
| Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood, 2004-03-25;104(2):314-20. 2004-03-25 [PMID: 15044249] (Bioassay, Human) |
Bioassay |
Human |
| Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem. J., 2004-06-01;380(0):425-33. 2004-06-01 [PMID: 14992689] (Bioassay, Human) |
Bioassay |
Human |
| Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia. J. Neuroimmunol., 2004-03-01;148(1):127-39. 2004-03-01 [PMID: 14975593] (Bioassay, Human) |
Bioassay |
Human |
| Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (ELISA (Standard)) |
ELISA (Standard) |
|
| Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22. 2004-01-12 [PMID: 14722222] (Bioassay, Human) |
Bioassay |
Human |
| Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood, 2003-09-25;103(3):1089-98. 2003-09-25 [PMID: 14512323] (Binding Assay, Human) |
Binding Assay |
Human |
| McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J. Clin. Invest., 2003-08-01;112(4):598-607. 2003-08-01 [PMID: 12925700] (Bioassay, Human) |
Bioassay |
Human |
| Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood, 2003-07-31;102(12):4084-9. 2003-07-31 [PMID: 12893768] (Bioassay, Human) |
Bioassay |
Human |
| Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma. Blood, 2003-07-24;102(10):3737-42. 2003-07-24 [PMID: 12881320] (Bioassay, Human) |
Bioassay |
Human |
| Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc. Natl. Acad. Sci. U.S.A., 2003-07-23;100(16):9452-7. 2003-07-23 [PMID: 12878725] (Bioassay, Human) |
Bioassay |
Human |
| Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection. J. Immunol., 2002-12-01;169(11):6361-8. 2002-12-01 [PMID: 12444143] (Bioassay, Human) |
Bioassay |
Human |
| Wang XB, Giscombe R, Yan Z Expression of CTLA-4 by human monocytes. Scand. J. Immunol., 2002-01-01;55(1):53-60. 2002-01-01 [PMID: 11841692] (Bioassay, Human) |
Bioassay |
Human |
| Barcena A, Park SW, Banapour B, Muench MO, Mechetner E Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood, 1996-09-15;88(6):2013-25. 1996-09-15 [PMID: 8822920] (Bioassay, Human) |
Bioassay |
Human |
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![SDS-PAGE TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg)
![Bioactivity TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg)
![SEC-MALS TNF-alpha [Unconjugated]](https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg)
![Bioactivity IL-4 [Unconjugated]](https://images.novusbio.com/images/protein/6507-ilcf_recombinant-human-il-4-cho-expressed-protein-cf-bioactivity-272020133214.jpg)
![Bioactivity IL-2 [Unconjugated]](https://images.novusbio.com/images/202-il_recombinant-human-il-2-protein-bioactivity-174202314946.jpg)
![N/A IL-10 [Biotin]](https://images.novusbio.com/images2/DATA_IL10_DY417_ELISA_2014.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/DATA_IL6_M6000_ELISA_936.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/IL-6_M6000_ELISA_415.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg)
![N/A IL-5 [HRP]](https://images.novusbio.com/images2/IL-5_M5000_ELISA_237.jpg)
![N/A IL-5 [HRP]](https://images.novusbio.com/images2/DATA_IL5_M5000_ELISA_935.jpg)
![SDS-PAGE IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_304.jpg)
![Bioactivity IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_306.jpg)
![SEC-MALS IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images/201-lb_recombinant-human-il-1-beta-il-1f2-protein-sec-mals-123202491556.jpg)
![Bioactivity CTLA-4 [Unconjugated]](https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg)
![N/A IL-13 [Biotin]](https://images.novusbio.com/images2/DATA_IL13_DY413_ELISA_2010.jpg)