Anderson, AE;Parashar, K;Jin, K;Clor, J;Stagnaro, CE;Vani, U;Singh, J;Chen, A;Guan, Y;Talukdar, P;Sathishkumar, P;Juat, DJ;Singh, H;Kushwaha, R;Zhao, X;Kaplan, A;Seitz, L;Walters, MJ;Fernandez-Salas, E;Walker, NPC;Bowman, CE; Characterization of AB598, a CD39 Enzymatic Inhibitory Antibody for the Treatment of Solid Tumors Molecular cancer therapeutics 2024-05-27 [PMID: 38797955] (Human) |
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Human |
Yildirim-Balatan, C;Fenyi, A;Besnault, P;Gomez, L;Sepulveda-Diaz, JE;Michel, PP;Melki, R;Hunot, S; Parkinson's disease-derived ?-synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype Journal of neuroinflammation 2024-02-21 [PMID: 38383421] (Bioassay, Human) |
Bioassay |
Human |
Múnera, JO;Kechele, DO;Bouffi, C;Qu, N;Jing, R;Maity, P;Enriquez, JR;Han, L;Campbell, I;Mahe, MM;McCauley, HA;Zhang, X;Sundaram, N;Hudson, JR;Zarsozo-Lacoste, A;Pradhan, S;Tominaga, K;Sanchez, JG;Weiss, AA;Chatuvedi, P;Spence, JR;Hachimi, M;North, T;Daley, GQ;Mayhew, CN;Hu, YC;Takebe, T;Helmrath, MA;Wells, JM; Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon Cell stem cell 2023-11-02 [PMID: 37922878] (Differentiation) |
Differentiation |
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Cortés-López, M;Chamely, P;Hawkins, AG;Stanley, RF;Swett, AD;Ganesan, S;Mouhieddine, TH;Dai, X;Kluegel, L;Chen, C;Batta, K;Furer, N;Vedula, RS;Beaulaurier, J;Drong, AW;Hickey, S;Dusaj, N;Mullokandov, G;Stasiw, AM;Su, J;Chaligné, R;Juul, S;Harrington, E;Knowles, DA;Potenski, CJ;Wiseman, DH;Tanay, A;Shlush, L;Lindsley, RC;Ghobrial, IM;Taylor, J;Abdel-Wahab, O;Gaiti, F;Landau, DA; Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths Cell stem cell 2023-08-09 [PMID: 37582363] (Bioassay, Human) |
Bioassay |
Human |
Y Yu, M Wang, XW Li, J Mao, YJ Zhu, N Wang, LH Yin, ZL Guo, H Cai, T Li, TT Liang, J Cui, T Zhou Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses Cell & bioscience, 2023-04-29;13(1):76. 2023-04-29 [PMID: 37120570] (Bioassay, Human) |
Bioassay |
Human |
JY Li, Y Zhao, S Gong, MM Wang, X Liu, QM He, YQ Li, SY Huang, H Qiao, XR Tan, ML Ye, XH Zhu, SW He, Q Li, YL Liang, KL Chen, SW Huang, QJ Li, J Ma, N Liu TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models Nature Communications, 2023-02-16;14(1):865. 2023-02-16 [PMID: 36797289] (Bioassay, Human) |
Bioassay |
Human |
H Zheng, X Yu, ML Ibrahim, D Foresman, M Xie, JO Johnson, TA Boyle, B Ruffell, BA Perez, SJ Antonia, N Ready, AN Saltos, MJ Cantwell, AA Beg Combination IFNbeta and membrane-stable CD40L maximize tumor dendritic cell activation and lymph node trafficking to elicit systemic T-cell immunity Cancer Immunology Research, 2023-04-03;0(0):. 2023-04-03 [PMID: 36757308] (Bioassay, Human) |
Bioassay |
Human |
D Kwart, J He, S Srivatsan, C Lett, J Golubov, EM Oswald, P Poon, X Ye, J Waite, AG Zaretsky, S Haxhinasto, E Au-Yeung, NT Gupta, J Chiu, C Adler, S Cherravuru, E Malahias, N Negron, K Lanza, A Coppola, M Ni, H Song, Y Wei, GS Atwal, L Macdonald, NS Oristian, W Poueymirou, V Jankovic, M Fury, I Lowy, AJ Murphy, MA Sleeman, B Wang, D Skokos Cancer cell-derived type I interferons instruct tumor monocyte polarization Cell Reports, 2022-12-06;41(10):111769. 2022-12-06 [PMID: 36476866] (Bioassay, Human) |
Bioassay |
Human |
H Salvator, A Cheng, LB Rosen, PR Williamson, JE Bennett, A Kashyap, L Ding, KJ Kwon-Chung, H Namkoong, CS Zerbe, SM Holland Neutralizing GM-CSF autoantibodies in pulmonary alveolar proteinosis, cryptococcal meningitis and severe nocardiosis Respiratory Research, 2022-10-11;23(1):280. 2022-10-11 [PMID: 36221098] (ELISA Development, Human) |
ELISA Development |
Human |
SP John, A Singh, J Sun, MJ Pierre, L Alsalih, C Lipsey, Z Traore, S Balcom-Luk, CJ Bradfield, J Song, TE Markowitz, M Smelkinson, M Ferrer, IDC Fraser Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection Cell Reports, 2022-09-15;0(0):111441. 2022-09-15 [PMID: 36179680] (Bioassay, Human) |
Bioassay |
Human |
YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells Science Advances, 2022-08-24;8(34):eabn5522. 2022-08-24 [PMID: 36001668] (Bioassay, Human) |
Bioassay |
Human |
F Zeng, S Liao, Z Kuang, Q Zhu, H Wei, J Shi, E Zheng, Z Xu, S Huang, L Hong, T Gu, J Yang, H Yang, G Cai, S Moisyadi, J Urschitz, Z Li, Z Wu Genetically Engineered Pigs as Efficient Salivary Gland Bioreactors for Production of Therapeutically Valuable Human Nerve Growth Factor Cells, 2022-08-02;11(15):. 2022-08-02 [PMID: 35954224] (Bioassay, Human) |
Bioassay |
Human |
SD van Haren, GK Pedersen, A Kumar, TJ Ruckwardt, S Moin, IN Moore, M Minai, M Liu, J Pak, F Borriello, S Doss-Golli, EMS Beijnen, S Ahmed, M Helmel, P Andersen, BS Graham, H Steen, D Christense, O Levy CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns Nature Communications, 2022-08-02;13(1):4234. 2022-08-02 [PMID: 35918315] (Bioassay, Human) |
Bioassay |
Human |
S Chen, RS Vedula, A Cuevas-Nav, B Lu, SJ Hogg, E Wang, S Benbarche, K Knorr, WJ Kim, RF Stanley, H Cho, C Erickson, M Singer, D Cui, S Tittley, BH Durham, TS Pavletich, E Fiala, MF Walsh, D Inoue, S Monette, J Taylor, N Rosen, F McCormick, RC Lindsley, P Castel, O Abdel-Waha Impaired proteolysis of non-canonical RAS proteins drives clonal hematopoietic transformation Cancer Discovery, 2022-10-05;0(0):. 2022-10-05 [PMID: 35904492] (Cell Culture, Human) |
Cell Culture |
Human |
IY Quiroga, AE Cruikshank, ML Bond, KSM Reed, BA Evangelist, JH Tseng, JV Ragusa, RB Meeker, H Won, S Cohen, TJ Cohen, DH Phanstiel Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems Journal of Neuroinflammation, 2022-04-23;19(1):99. 2022-04-23 [PMID: 35459147] (Bioassay, Human) |
Bioassay |
Human |
P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells Cancers, 2022-03-11;14(6):. 2022-03-11 [PMID: 35326601] (Cell Culture, Human) |
Cell Culture |
Human |
H Farese, Farese H, M Noack, Noack M, P Miossec Synoviocytes from pigmented villonodular synovitis are less sensitive to cadmium-induced cell death than synoviocytes from rheumatoid arthritis. Sci Rep, 2022-03-09;12(1):3832. 2022-03-09 [PMID: 35264617] (Bioassay, Human) |
Bioassay |
Human |
Y Li, Y Zhu, S Feng, Y Ishida, TP Chiu, T Saito, S Wang, DK Ann, JJ Ou Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1beta to downregulate PPARalpha and FOXO3 Cell Reports, 2022-01-25;38(4):110284. 2022-01-25 [PMID: 35081341] (Bioassay, Human) |
Bioassay |
Human |
R Sagawa, S Sakata, B Gong, Y Seto, A Takemoto, S Takagi, H Ninomiya, N Yanagitani, M Nakao, M Mun, K Uchibori, M Nishio, Y Miyazaki, Y Shiraishi, S Ogawa, K Kataoka, N Fujita, K Takeuchi, R Katayama Soluble PD-L1 through alternative polyadenylation works as a decoy in lung cancer immunotherapy JCI Insight, 2022-01-11;0(0):. 2022-01-11 [PMID: 34874919] (Bioassay, Human) |
Bioassay |
Human |
Y Qiao, Y Qiu, J Ding, N Luo, H Wang, X Ling, J Sun, Z Wu, Y Wang, Y Liu, F Guo, T Sun, W Shen, M Zhang, D Wu, B Chen, W Xu, X Wang Cancer immune therapy with PD-1-dependent CD137 co-stimulation provides localized tumour killing without systemic toxicity Nature Communications, 2021-11-04;12(1):6360. 2021-11-04 [PMID: 34737267] (Bioassay, Human) |
Bioassay |
Human |
MD Cherne, B Sidar, TA Sebrell, HS Sanchez, K Heaton, FJ Kassama, MM Roe, AB Gentry, CB Chang, ST Walk, M Jutila, JN Wilking, D Bimczok A Synthetic Hydrogel, VitroGel� ORGANOID-3, Improves Immune Cell-Epithelial Interactions in a Tissue Chip Co-Culture Model of Human Gastric Organoids and Dendritic Cells Frontiers in Pharmacology, 2021-09-06;12(0):707891. 2021-09-06 [PMID: 34552484] (Bioassay, Human) |
Bioassay |
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A Banerjee, Y Lu, K Do, T Mize, X Wu, X Chen, J Chen Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases Frontiers in Cellular Neuroscience, 2021-04-09;15(0):629279. 2021-04-09 [PMID: 33897370] (Bioassay, Human) |
Bioassay |
Human |
D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, Y Hayashi, JMB Pineda, E El Marabti, C Erickson, K Knorr, M Fukumoto, H Yamazaki, A Tanaka, C Fukui, SX Lu, BH Durham, B Liu, E Wang, S Mehta, D Zakheim, R Garippa, A Penson, GL Chew, F McCormick, RK Bradley, O Abdel-Waha Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition Nature Genetics, 2021-04-12;0(0):. 2021-04-12 [PMID: 33846634] (Bioassay, Human) |
Bioassay |
Human |
R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility Cell Reports, 2021-03-23;34(12):108891. 2021-03-23 [PMID: 33761354] (Bioassay, Human) |
Bioassay |
Human |
Bsat M, Mehta H, Rubio M, Sarfati M The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages. Curr Protoc, 2021-03-01;1(3):e74. 2021-03-01 [PMID: 33705607] (Bioassay, Human) |
Bioassay |
Human |
J Li, A Wuethrich, AAI Sina, HH Cheng, Y Wang, A Behren, PN Mainwaring, M Trau A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy Nature Communications, 2021-02-17;12(1):1087. 2021-02-17 [PMID: 33597530] (Human) |
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Human |
M Drill, KL Powell, LK Kan, NC Jones, TJ O'Brien, JA Hamilton, M Monif Inhibition of purinergic P2X receptor 7 (P2X7R) decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) expression in U251 glioblastoma cells Sci Rep, 2020-09-09;10(1):14844. 2020-09-09 [PMID: 32908225] (Cell Culture, Human) |
Cell Culture |
Human |
B Cioni, A Zaalberg, JR van Beijnu, MHM Melis, J van Burgst, MJ Muraro, E Hooijberg, D Peters, I Hofland, Y Lubeck, J de Jong, J Sanders, J Vivié, HG van der Po, JP de Boer, AW Griffioen, W Zwart, AM Bergman Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion Nat Commun, 2020-09-09;11(1):4498. 2020-09-09 [PMID: 32908142] (Bioassay, Human) |
Bioassay |
Human |
S Vakili, TM Ahooyi, SS Yarandi, M Donadoni, J Rappaport, IK Sariyer Molecular and Cellular Impact of Inflammatory Extracellular Vesicles (EVs) Derived from M1 and M2 Macrophages on Neural Action Potentials Brain Sci, 2020-07-03;10(7):. 2020-07-03 [PMID: 32635207] (Bioassay, Human) |
Bioassay |
Human |
X Guo, Y Pan, M Xiong, S Sanapala, C Anastasaki, O Cobb, S Dahiya, DH Gutmann Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth Nat Commun, 2020-05-01;11(1):2177. 2020-05-01 [PMID: 32358581] (Cell Culture, Human) |
Cell Culture |
Human |
J Lubow, MC Virgilio, M Merlino, DR Collins, M Mashiba, BG Peterson, Z Lukic, MM Painter, F Gomez-Rive, V Terry, G Zimmerman, KL Collins Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages Elife, 2020-03-02;9(0):. 2020-03-02 [PMID: 32119644] (Bioassay, Human) |
Bioassay |
Human |
B ?y?y?ska-G, B Trzaskowsk, M Dutkiewicz, O Zegrocka-S, M Machci?ska, K Bocian, M Kowalewska, K Koziak The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor Sci Rep, 2020-02-19;10(1):2886. 2020-02-19 [PMID: 32076052] (Cell Culture, Human) |
Cell Culture |
Human |
H Xiang, CP Ramil, J Hai, C Zhang, H Wang, AA Watkins, R Afshar, P Georgiev, MA Sze, XS Song, PJ Curran, M Cheng, JR Miller, D Sun, A Loboda, Y Jia, LY Moy, A Chi, PE Brandish Cancer-associated fibroblasts promote immunosuppression by inducing ROS-generating monocytic MDSCs in lung squamous cell carcinoma Cancer Immunol Res, 2020-02-19;0(0):. 2020-02-19 [PMID: 32075803] (Bioassay, Human) |
Bioassay |
Human |
JS Brunner, L Vulliard, M Hofmann, M Kieler, A Lercher, A Vogel, M Russier, JB Brüggenthi, M Kerndl, V Saferding, B Niederreit, A Junza, A Frauenstei, C Scholtysek, Y Mikami, K Klavins, G Krönke, A Bergthaler, JJ O'Shea, T Weichhart, F Meissner, JS Smolen, P Cheng, O Yanes, J Menche, PJ Murray, O Sharif, S Blüml, G Schabbauer Environmental arginine controls multinuclear giant cell metabolism and formation Nat Commun, 2020-01-22;11(1):431. 2020-01-22 [PMID: 31969567] (Differentiation, Differentiation, Human) |
Differentiation, Differentiation |
Human |
JJ Montoya, MA Turnidge, DH Wai, AR Patel, DW Lee, V Gokhale, LH Hurley, RJ Arceci, C Wetmore, DO Azorsa In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells BMC Cancer, 2019-12-27;19(1):1251. 2019-12-27 [PMID: 31881855] (Bioassay, Human) |
Bioassay |
Human |
R Chen, G Ji, H Ren, Z Liu, S Feng, T Zhang, L Xi, X Li Activation of autophagy and IL-10 production are regulated by Jun N-terminal kinase 1 and 2 and p38 mitogen activated protein kinase signaling pathways during Talaromyces marneffei infection within dendritic cells Microb. Pathog., 2019-11-26;139(0):103891. 2019-11-26 [PMID: 31783123] (Cell Culture, Human) |
Cell Culture |
Human |
S Patel, R Hanajiri, M Grant, D Saunders, S Van Pelt, M Keller, PJ Hanley, G Simon, DF Nixon, D Hardy, RB Jones, CM Bollard HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform Mol Ther Methods Clin Dev, 2019-10-11;16(0):11-20. 2019-10-11 [PMID: 31720305] (Cell Culture, Human) |
Cell Culture |
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N Chiang, S Libreros, PC Norris, X de la Rosa, CN Serhan Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions J. Clin. Invest., 2019-12-02;0(0):. 2019-12-02 [PMID: 31657786] (Cell Culture, Human) |
Cell Culture |
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A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, SC Lee, JB Micol, XJ Zhang, S de Botton, V Penard-Lac, EM Stein, H Cho, RE Miles, D Inoue, TR Albrecht, TCP Somervaill, K Batta, F Amaral, F Simeoni, DP Wilks, C Cargo, AM Intlekofer, RL Levine, H Dvinge, RK Bradley, EJ Wagner, AR Krainer, O Abdel-Waha Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis Nature, 2019-10-02;0(0):. 2019-10-02 [PMID: 31578525] (Cell Culture, Human) |
Cell Culture |
Human |
SR Levan, KA Stamnes, DL Lin, AR Panzer, E Fukui, K McCauley, KE Fujimura, M McKean, DR Ownby, EM Zoratti, HA Boushey, MD Cabana, CC Johnson, SV Lynch Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance Nat Microbiol, 2019-07-22;4(11):1851-1861. 2019-07-22 [PMID: 31332384] (Cell Culture, Human) |
Cell Culture |
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A Crotti, HR Sait, KM McAvoy, K Estrada, A Ergun, S Szak, G Marsh, L Jandreski, M Peterson, TL Reynolds, I Dalkilic-L, A Cameron, E Cahir-McFa, RM Ransohoff BIN1 favors the spreading of Tau via extracellular vesicles Sci Rep, 2019-07-01;9(1):9477. 2019-07-01 [PMID: 31263146] (Cell Culture, Human) |
Cell Culture |
Human |
AI Chiramel, NR Meyerson, KL McNally, RM Broeckel, VR Montoya, O Méndez-Sol, SJ Robertson, GL Sturdevant, KJ Lubick, V Nair, BH Youseff, RM Ireland, CM Bosio, K Kim, J Luban, VM Hirsch, RT Taylor, F Bouamr, SL Sawyer, SM Best TRIM5? Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation Cell Rep, 2019-06-11;27(11):3269-3283.e6. 2019-06-11 [PMID: 31189110] (Bioassay, Human) |
Bioassay |
Human |
BD Bryson, TR Rosebrock, FG Tafesse, CY Itoh, A Nibasumba, GH Babunovic, B Corleis, C Martin, C Keegan, P Andrade, S Realegeno, D Kwon, RL Modlin, SM Fortune Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis Nat Commun, 2019-05-27;10(1):2329. 2019-05-27 [PMID: 31133636] (Bioassay, Human) |
Bioassay |
Human |
VA Jennings, GB Scott, AMS Rose, KJ Scott, G Migneco, B Keller, K Reilly, O Donnelly, H Peach, D Dewar, KJ Harrington, H Pandha, A Samson, RG Vile, AA Melcher, F Errington- Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition Mol. Ther., 2019-04-14;0(0):. 2019-04-14 [PMID: 31053413] (Bioassay, Human) |
Bioassay |
Human |
S De Alessan, GJ Ferguson, AJ Dodd, JK Juss, A Devaprasad, S Piper, O Wyatt, H Killick, DJ Corkill, ES Cohen, A Pandit, TRDJ Radstake, R Simmonds, AM Condliffe, MA Sleeman, AS Cowburn, DK Finch, ER Chilvers Neutrophil GM-CSF receptor dynamics in acute lung injury J. Leukoc. Biol., 2019-04-03;0(0):. 2019-04-03 [PMID: 30942918] (Bioassay, Human) |
Bioassay |
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R Gramlich, E Aliahmadi, M Peiser In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists Int J Mol Sci, 2019-03-19;20(6):. 2019-03-19 [PMID: 30893757] (Bioassay, Human) |
Bioassay |
Human |
JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis J Immunol Res, 2019-02-06;2019(0):1529189. 2019-02-06 [PMID: 30882002] (Bioassay, Human) |
Bioassay |
Human |
TA Sebrell, M Hashimi, B Sidar, R Wilkinson, L Kirpotina, MT Quinn, Z Malkoç, PJ Taylor, JN Wilking, D Bimczok A Novel Gastric Spheroid Co-Culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium Cell Mol Gastroenterol Hepatol, 2019-03-13;0(0):. 2019-03-13 [PMID: 30878664] (Bioassay, Human) |
Bioassay |
Human |
M Kita, Y Ano, A Inoue, J Aoki Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells Sci Rep, 2019-02-28;9(1):3135. 2019-02-28 [PMID: 30816271] (Bioassay, Human) |
Bioassay |
Human |
E Tenland, A Pochert, N Krishnan, K Umashankar, S Kalsum, K Braun, I Glegola-Ma, M Lerm, BD Robertson, M Lindén, G Godaly Effective delivery of the anti-mycobacterial peptide NZX in mesoporous silica nanoparticles PLoS ONE, 2019-02-26;14(2):e0212858. 2019-02-26 [PMID: 30807612] (Bioassay, Human) |
Bioassay |
Human |
CM Sellgren, J Gracias, B Watmuff, JD Biag, JM Thanos, PB Whittredge, T Fu, K Worringer, HE Brown, J Wang, A Kaykas, R Karmachary, CP Goold, SD Sheridan, RH Perlis Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning Nat. Neurosci., 2019-02-04;0(0):. 2019-02-04 [PMID: 30718903] (Bioassay, Human) |
Bioassay |
Human |
M Pujol, C Borie, M Montoya, A Ferreira, R Vernal Brucella canis induces canine CD4+ T cells multi-cytokine Th1/Th17 production via dendritic cell activation Comp. Immunol. Microbiol. Infect. Dis., 2018-11-30;62(0):68-75. 2018-11-30 [PMID: 30711049] (Bioassay, Canine, Human) |
Bioassay |
Canine, Human |
C Kim, B Hu, RR Jadhav, J Jin, H Zhang, MM Cavanagh, RS Akondy, R Ahmed, CM Weyand, JJ Goronzy Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells Cell Rep, 2018-11-20;25(8):2148-2162.e5. 2018-11-20 [PMID: 30463012] (Bioassay, Human) |
Bioassay |
Human |
K Vaeteewoot, R Kariya, P Pothipan, S Fujikawa, C Pairojkul, S Waraasawap, K Kuwahara, C Wongkham, S Wongkham, S Okada Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis Transl Oncol, 2018-11-09;12(2):217-225. 2018-11-09 [PMID: 30415063] (Bioassay, Human) |
Bioassay |
Human |
AS Hansen, M Biltoft, B Bundgaard, AB Bohn, BK Møller, P Höllsberg CD46 activation induces distinct CXCL-10 response in monocytes and monocyte-derived dendritic cells Cytokine, 2018-07-04;0(0):. 2018-07-04 [PMID: 29980471] (Bioassay, Human) |
Bioassay |
Human |
J Zhang, Z Xiang, PA Malaviarac, Y Yan, NJ Baltz, PD Emanuel, YL Liu PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia Cell. Signal., 2018-06-28;50(0):72-79. 2018-06-28 [PMID: 29964149] (Bioassay, Human) |
Bioassay |
Human |
ME Kirkling, U Cytlak, CM Lau, KL Lewis, A Resteu, A Khodadadi-, CW Siebel, H Salmon, M Merad, A Tsirigos, M Collin, V Bigley, B Reizis Notch Signaling Facilitates In�Vitro Generation of Cross-Presenting Classical Dendritic Cells Cell Rep, 2018-06-19;23(12):3658-3672.e6. 2018-06-19 [PMID: 29925006] (Bioassay, Human) |
Bioassay |
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H Nakano, Y Kirino, M Takeno, K Higashitan, H Nagai, R Yoshimi, Y Yamaguchi, I Kato, I Aoki, H Nakajima GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Beh�et's disease Arthritis Res. Ther., 2018-06-12;20(1):124. 2018-06-12 [PMID: 29895319] (Bioassay, Human) |
Bioassay |
Human |
H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RK Au-Yeung, KH Sze, D Yang, H Shuai, Y Hou, C Li, X Zhao, VK Poon, SP Leung, ML Yeung, J Yan, G Lu, DY Jin, GF Gao, JF Chan, KY Yuen Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells J. Biol. Chem., 2018-06-10;0(0):. 2018-06-10 [PMID: 29887526] (Bioassay, Human) |
Bioassay |
Human |
JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation Cell Death Dis, 2018-06-04;9(6):665. 2018-06-04 [PMID: 29867198] (Bioassay, Human) |
Bioassay |
Human |
L Ladislau, DM Portilho, T Courau, A Solares-Pé, E Negroni, J Lainé, D Klatzmann, A Bonomo, Y Allenbach, O Benveniste, I Riederer, W Savino, V Mouly, G Butler-Bro, CF Benjamim Activated dendritic cells modulate proliferation and differentiation of human myoblasts Cell Death Dis, 2018-05-01;9(5):551. 2018-05-01 [PMID: 29748534] (Bioassay, Human) |
Bioassay |
Human |
LB Crawford, JH Kim, D Collins-Mc, BJ Lee, I Landais, C Held, JA Nelson, AD Yurochko, P Caposio Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation MBio, 2018-04-24;9(2):. 2018-04-24 [PMID: 29691342] (Bioassay, Human) |
Bioassay |
Human |
JAT de Albuque, PP Banerjee, A Castoldi, R Ma, NB Zurro, LH Ynoue, C Arslanian, MUW Barbosa-Ca, JEM Correia-De, FG Weiler, MR Dias-da-Si, M Lazaretti-, LA Pedroza, NOS Câmara, E Mace, JS Orange, A Condino-Ne The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages Front Immunol, 2018-03-21;9(0):567. 2018-03-21 [PMID: 29666621] (Cell Culture, Human) |
Cell Culture |
Human |
D Kishimoto, Y Kirino, M Tamura, M Takeno, Y Kunishita, K Takase-Min, H Nakano, I Kato, K Nagahama, R Yoshimi, K Igarashi, I Aoki, H Nakajima Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons Arthritis Res. Ther., 2018-04-10;20(1):64. 2018-04-10 [PMID: 29636091] (Bioassay, Human) |
Bioassay |
Human |
A Alflen, N Stadler, P Aranda Lop, D Teschner, M Theobald, G He beta , MP Radsak Idelalisib impairs TREM-1 mediated neutrophil inflammatory responses Sci Rep, 2018-04-03;8(1):5558. 2018-04-03 [PMID: 29615799] (Bioassay, Human) |
Bioassay |
Human |
X de la Rosa, PC Norris, N Chiang, AR Rodriguez, BW Spur, CN Serhan Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration Am. J. Pathol., 2018-04-01;188(4):950-966. 2018-04-01 [PMID: 29571326] (Bioassay, Human) |
Bioassay |
Human |
X Chen, S Hao, Z Zhao, J Liu, Q Shao, F Wang, D Sun, Y He, W Gao, H Mao Interleukin 35: Inhibitory regulator in monocyte-derived dendritic cell maturation and activation Cytokine, 2018-03-20;108(0):43-52. 2018-03-20 [PMID: 29571039] (Bioassay, Human) |
Bioassay |
Human |
C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti Anisakis pegreffii impacts differentiation and function of human dendritic cells Parasite Immunol., 2018-05-01;0(0):e12527. 2018-05-01 [PMID: 29569735] (Bioassay, Human) |
Bioassay |
Human |
S Zheng, E Papalexi, A Butler, W Stephenson, R Satija Molecular transitions in early progenitors during human cord blood hematopoiesis Mol. Syst. Biol., 2018-03-15;14(3):e8041. 2018-03-15 [PMID: 29545397] (Bioassay, Human) |
Bioassay |
Human |
T Kato, T Matsuda, Y Ikeda, JH Park, M Leisegang, S Yoshimura, T Hikichi, M Harada, M Zewde, S Sato, K Hasegawa, K Kiyotani, Y Nakamura Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells Oncotarget, 2018-01-13;9(13):11009-11019. 2018-01-13 [PMID: 29541393] (Bioassay, Human) |
Bioassay |
Human |
HD Chae, N Cox, GV Dahl, NJ Lacayo, KL Davis, S Capolicchi, M Smith, KM Sakamoto Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways Oncotarget, 2017-12-31;9(4):4301-4317. 2017-12-31 [PMID: 29435104] (Bioassay, Human) |
Bioassay |
Human |
N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4 Front Immunol, 2018-01-24;9(0):11. 2018-01-24 [PMID: 29416536] (Bioassay, Human) |
Bioassay |
Human |
D Wang, XF Huang, B Hong, XT Song, L Hu, M Jiang, B Zhang, H Ning, Y Li, C Xu, X Lou, B Li, Z Yu, J Hu, J Chen, F Yang, H Gao, G Ding, L Liao, L Rollins, L Jones, SY Chen, H Chen Efficacy of intracellular immune checkpoint-silenced DC vaccine JCI Insight, 2018-02-08;3(3):. 2018-02-08 [PMID: 29415891] (Bioassay, Human) |
Bioassay |
Human |
H Sic, M Speletas, V Cornacchio, M Seidl, M Beibel, B Linghu, F Yang, E Sevdali, AE Germenis, EJ Oakeley, E Vangreveli, AW Sailer, E Traggiai, H Gram, H Eibel An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation Syndrome Front Immunol, 2017-12-15;8(0):1824. 2017-12-15 [PMID: 29375547] (Bioassay, Human) |
Bioassay |
Human |
MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression Front Immunol, 2017-12-13;8(0):1777. 2017-12-13 [PMID: 29326692] (Bioassay, Human) |
Bioassay |
Human |
YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells PLoS ONE, 2018-01-03;13(1):e0190638. 2018-01-03 [PMID: 29298343] (Bioassay, Human) |
Bioassay |
Human |
C Ge, R Li, H Song, T Geng, J Yang, Q Tan, L Song, Y Wang, Y Xue, Z Li, S Dong, Z Zhang, N Zhang, J Guo, L Hua, S Chen, X Song Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC BMC Cancer, 2017-12-21;17(1):884. 2017-12-21 [PMID: 29268708] (Bioassay, Human) |
Bioassay |
Human |
M Ohgidani, TA Kato, M Hosoi, M Tsuda, K Hayakawa, C Hayaki, R Iwaki, N Sagata, R Hashimoto, K Inoue, N Sudo, S Kanba Fibromyalgia and microglial TNF-?: Translational research using human blood induced microglia-like cells Sci Rep, 2017-09-19;7(1):11882. 2017-09-19 [PMID: 28928366] (Bioassay, Human) |
Bioassay |
Human |
M Yoshida, Y Ishioka, T Ozawa, H Okuyama, M Iguchi, T Ota, T Ito, M Nagira, A Morita, H Tanaka, H Naito, H Kidoya, N Takakura Soluble HLA-associated peptide from PSF1 has a cancer vaccine potency Sci Rep, 2017-09-11;7(1):11137. 2017-09-11 [PMID: 28894200] (Bioassay, Human) |
Bioassay |
Human |
H Nishi, K Furuhashi, X Cullere, G Saggu, MJ Miller, Y Chen, F Rosetti, SL Hamilton, L Yang, SP Pittman, J Liao, JM Herter, JC Berry, DJ DeAngelo, C Zhu, GC Tsokos, TN Mayadas Neutrophil Fc?RIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases J. Clin. Invest., 2017-09-11;0(0):. 2017-09-11 [PMID: 28891817] (Bioassay, Human) |
Bioassay |
Human |
M Matsushita, K Ozawa, T Suzuki, M Nakamura, N Nakano, S Kanchi, D Ichikawa, E Matsuki, M Sakurai, D Karigane, H Kasahara, N Tsukamoto, T Shimizu, T Mori, H Nakajima, S Okamoto, Y Kawakami, Y Hattori CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients Blood Cancer J, 2017-09-01;7(9):e601. 2017-09-01 [PMID: 28862699] (Bioassay, Human) |
Bioassay |
Human |
P Thornton, J Sevalle, MJ Deery, G Fraser, Y Zhou, S Ståhl, EH Franssen, RB Dodd, S Qamar, B Gomez Pere, LS Nicol, S Eketjäll, J Revell, C Jones, A Billinton, PH St George-, I Chessell, DC Crowther TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant EMBO Mol Med, 2017-10-01;0(0):. 2017-10-01 [PMID: 28855301] (Bioassay, Human) |
Bioassay |
Human |
L Butcher, M Ahluwalia, T Örd, J Johnston, RH Morris, E Kiss-Toth, T Örd, JD Erusalimsk Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis Sci Rep, 2017-07-27;7(1):6684. 2017-07-27 [PMID: 28751721] (Bioassay, Human) |
Bioassay |
Human |
J Helft, F Anjos-Afon, AG van der Ve, P Chakravart, D Bonnet, C Reis E Sou Dendritic Cell Lineage Potential in Human Early Hematopoietic Progenitors Cell Rep, 2017-07-18;20(3):529-537. 2017-07-18 [PMID: 28723558] (Bioassay, Human) |
Bioassay |
Human |
JH von Steman, AS Rigas, LW Thørner, DGK Rasmussen, OB Pedersen, K Rostgaard, C Erikstrup, H Ullum, MB Hansen Prevalence and correlation of cytokine-specific autoantibodies with epidemiological factors and C-reactive protein in 8,972 healthy individuals: Results from the Danish Blood Donor Study PLoS ONE, 2017-06-30;12(6):e0179981. 2017-06-30 [PMID: 28665954] (Control, Human) |
Control |
Human |
JT Schroeder, AP Bieneman Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of Allergen J. Immunol., 2017-06-26;0(0):. 2017-06-26 [PMID: 28652400] (Bioassay, Human) |
Bioassay |
Human |
S Scholz, F Baharom, G Rankin, KT Maleki, S Gupta, S Vangeti, J Pourazar, A Discacciat, J Höijer, M Bottai, NK Björkström, J Rasmuson, M Evander, A Blomberg, HG Ljunggren, J Klingström, C Ahlm, A Smed-Sören Human hantavirus infection elicits pronounced redistribution of mononuclear phagocytes in peripheral blood and airways PLoS Pathog., 2017-06-22;13(6):e1006462. 2017-06-22 [PMID: 28640917] (Bioassay, Human) |
Bioassay |
Human |
AA Panackal, LB Rosen, G Uzel, MJ Davis, G Hu, A Adeyemo, F Tekola-Aye, A Lisco, C Diachok, JD Kim, D Shaw, I Sereti, J Stoddard, J Niemela, SD Rosenzweig, JE Bennett, PR Williamson Susceptibility to Cryptococcal Meningoencephalitis Associated With Idiopathic CD4(+) Lymphopenia and Secondary Germline or Acquired Defects Open Forum Infect Dis, 2017-06-07;4(2):ofx082. 2017-06-07 [PMID: 28638843] (Bioassay, Human) |
Bioassay |
Human |
T Liu, P Jia, H Ma, SA Reed, X Luo, HB Larman, PG Schultz Construction and Screening of a Lentiviral Secretome Library Cell Chem Biol, 2017-06-09;0(0):. 2017-06-09 [PMID: 28602759] (Bioassay, Human) |
Bioassay |
Human |
AM Clemente, G Castronovo, A Antonelli, MM D'Andrea, M Tanturli, E Perissi, S Paccosi, A Parenti, F Cozzolino, GM Rossolini, MG Torcia Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase PLoS ONE, 2017-06-06;12(6):e0178847. 2017-06-06 [PMID: 28586386] (Bioassay, Human) |
Bioassay |
Human |
CSB Viegas, RM Costa, L Santos, PA Videira, Z Silva, N Araújo, AL Macedo, AP Matos, C Vermeer, DC Simes Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases PLoS ONE, 2017-05-18;12(5):e0177829. 2017-05-18 [PMID: 28542410] (Bioassay, Human) |
Bioassay |
Human |
J Wang, H Ye, D Zhang, K Cheng, Y Hu, X Yu, L Lu, J Hu, C Zuo, B Qian, Y Yu, S Liu, G Liu, C Mao, S Liu Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs Theranostics, 2017-03-24;7(6):1407-1421. 2017-03-24 [PMID: 28529626] (Bioassay, Human) |
Bioassay |
Human |
H Zhao, S Gulesseria, MC Malinao, S Kumar-Gane, J Song, MS Chang, MM Williams, Z Zeng, M Mattie, BA Mendelsohn, DR Stover, F Doñate A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise Mol. Cancer Ther., 2017-05-18;0(0):. 2017-05-18 [PMID: 28522588] (Bioassay, Human) |
Bioassay |
Human |
SC Silva-Card, AJ Affandi, L Spel, M Cossu, JAG van Roon, M Boes, TRDJ Radstake CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells J. Immunol., 2017-05-17;0(0):. 2017-05-17 [PMID: 28515281] (Bioassay, Human) |
Bioassay |
Human |
G Izumi, K Koga, M Takamura, W Bo, M Nagai, M Miyashita, M Harada, T Hirata, Y Hirota, O Yoshino, T Fujii, Y Osuga Oil-Soluble Contrast Medium (OSCM) for Hysterosalpingography Modulates Dendritic Cell and Regulatory T Cell Profiles in the Peritoneal Cavity: A Possible Mechanism by Which OSCM Enhances Fertility J. Immunol., 2017-04-28;0(0):. 2017-04-28 [PMID: 28455434] (Bioassay, Human) |
Bioassay |
Human |
A Dyer, Y Di, H Calderon, S Illingwort, G Kueberuwa, A Tedcastle, P Jakeman, SL Chia, A Brown, MA Silva, D Barlow, J Beadle, T Hermiston, DJ Ferguson, B Champion, KD Fisher, LW Seymour Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators Mol Ther Oncolytics, 2016-12-10;4(0):18-30. 2016-12-10 [PMID: 28345021] (Bioassay, Human) |
Bioassay |
Human |
X Zhang, T Zhou, J Yang, Y Lin, J Shi, X Zhang, DA Frabutt, X Zeng, S Li, PJ Venta, YH Zheng Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction J. Virol, 2017-04-28;0(0):. 2017-04-28 [PMID: 28275190] (Bioassay, Human) |
Bioassay |
Human |
M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells Clin. Cancer Res, 2017-02-09;0(0):. 2017-02-09 [PMID: 28183713] (Bioassay, Human) |
Bioassay |
Human |
C Li, Y Bi, Y Li, H Yang, Q Yu, J Wang, Y Wang, H Su, A Jia, Y Hu, L Han, J Zhang, S Li, W Tao, G Liu Dendritic cell MST1 inhibits Th17 differentiation Nat Commun, 2017-02-01;8(0):14275. 2017-02-01 [PMID: 28145433] (Bioassay, Human) |
Bioassay |
Human |
JE Hammonds, N Beeman, L Ding, S Takushi, AC Francis, JJ Wang, GB Melikyan, P Spearman Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1 PLoS Pathog, 2017-01-27;13(1):e1006181. 2017-01-27 [PMID: 28129379] (Bioassay, Human) |
Bioassay |
Human |
MJ Bae, S Ryu, HJ Kim, SI Cha, CH Kim, J Lee Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages Tuberc Respir Dis (Seoul), 2016-12-30;80(1):77-82. 2016-12-30 [PMID: 28119750] (Bioassay, Human) |
Bioassay |
Human |
Stephane Esnault IL-3 Up-regulates and Activates Human Eosinophil CD32 and ?M�2 Integrin Causing Degranulation Clin. Exp. Allergy, 2017-01-23;0(0):. 2017-01-23 [PMID: 28000949] (Bioassay, Human) |
Bioassay |
Human |
Yusuke Tomita The interplay of epigenetic therapy and immunity in locally recurrent or metastatic estrogen receptor-positive breast cancer: Correlative analysis of ENCORE 301, a randomized, placebo-controlled phase II trial of exemestane with or without entinostat Oncoimmunology, 2016-08-31;5(11):e1219008. 2016-08-31 [PMID: 27999738] (Bioassay, Human) |
Bioassay |
Human |
Eóin N McNamee Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis Allergy, 2017-01-23;0(0):. 2017-01-23 [PMID: 27926989] (Bioassay, Human) |
Bioassay |
Human |
Jiang Zheng 1400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia Behav. Brain Res., 2016-11-22;319(0):188-199. 2016-11-22 [PMID: 27888018] (Bioassay, Rat) |
Bioassay |
Rat |
Xiang-Ming Lao Peritumoral stromal neutrophils are essential for c-Met-elicited metastasis in human hepatocellular carcinoma Oncoimmunology, 2016-09-27;5(10):e1219828. 2016-09-27 [PMID: 27853643] (Bioassay, Human) |
Bioassay |
Human |
Guangxin Li Comparative analysis of the interaction of HSPs in dendritic cells, macrophages, RGM-1 cells infected by Helicobacter pylori Am J Transl Res, 2016-10-15;8(10):4184-4194. 2016-10-15 [PMID: 27830002] (Bioassay, Rat) |
Bioassay |
Rat |
CD11c/CD18 Dominates Adhesion of Human Monocytes, Macrophages and Dendritic Cells over CD11b/CD18 PLoS ONE, 2016-09-22;11(9):e0163120. 2016-09-22 [PMID: 27658051] (Bioassay, Human) |
Bioassay |
Human |
Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes Immunology, 2016-09-30;0(0):. 2016-09-30 [PMID: 27568595] (Bioassay, Human) |
Bioassay |
Human |
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation J Clin Invest, 2016-08-15;0(0):. 2016-08-15 [PMID: 27525438] (Bioassay, Human) |
Bioassay |
Human |
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation J Immunol, 2016-08-12;0(0):. 2016-08-12 [PMID: 27521339] (Bioassay, Human) |
Bioassay |
Human |
Sarah E Clark Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection PLoS Pathog, 2016-06-13;12(6):e1005708. 2016-06-13 [PMID: 27295349] (Bioassay, Human) |
Bioassay |
Human |
Lajos V Kemény Melanoma Cells Can Adopt the Phenotype of Stromal Fibroblasts and Macrophages by Spontaneous Cell Fusion in Vitro Int J Mol Sci, 2016-06-02;17(6):. 2016-06-02 [PMID: 27271591] (Bioassay, Human) |
Bioassay |
Human |
K Mahiddine, A Mallaviall, H Bziouech, F Larbret, A Bernard, G Bernard CD99 isoforms regulate CD1a expression in human monocyte-derived DCs through ATF-2/CREB-1 phosphorylation Eur J Immunol, 2016-05-06;0(0):. 2016-05-06 [PMID: 27094031] (Bioassay, Human) |
Bioassay |
Human |
Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming Oncotarget, 2016-05-24;7(21):30193-210. 2016-05-24 [PMID: 27070086] (Bioassay, Human) |
Bioassay |
Human |
Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts Blood, 2016-03-24;127(23):2879-89. 2016-03-24 [PMID: 27013443] (Bioassay, Human) |
Bioassay |
Human |
TM Garcia-Bat, E Kim, F Concha-Ben, S Trivedi, RB Mailliard, A Gambotto, RL Ferris Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1 J. Immunol, 2016-02-05;196(6):2870-8. 2016-02-05 [PMID: 26851223] (Bioassay, Human) |
Bioassay |
Human |
Younis R, Han K, Webb T Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells. J Immunol, 2016-01-06;196(3):1419-29. 2016-01-06 [PMID: 26740106] (Bioassay, Human) |
Bioassay |
Human |
Tufariello J, Chapman J, Kerantzas C, Wong K, Vilcheze C, Jones C, Cole L, Tinaztepe E, Thompson V, Fenyo D, Niederweis M, Ueberheide B, Philips J, Jacobs W Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence. Proc Natl Acad Sci U S A, 2016-01-04;113(3):E348-57. 2016-01-04 [PMID: 26729876] (Bioassay, Human) |
Bioassay |
Human |
BR Yoon, YH Chung, SJ Yoo, K Kawara, J Kim, IS Yoo, CG Park, SW Kang, WW Lee Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis J. Biol. Chem, 2015-12-23;291(8):4048-57. 2015-12-23 [PMID: 26702052] (Bioassay, Human) |
Bioassay |
Human |
Chai S, Yap Y, Foo Y, Yap L, Ponniah S, Teo S, Cheong S, Patel V, Lim K Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma. PLoS ONE, 2015-11-04;10(11):e0130464. 2015-11-04 [PMID: 26536470] (Bioassay, Human) |
Bioassay |
Human |
Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells. Exp Hematol, 2015-10-23;44(1):68-74.e10. 2015-10-23 [PMID: 26477526] (Bioassay, Human) |
Bioassay |
Human |
Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? PLoS ONE, 2015-07-21;10(7):e0133392. 2015-07-21 [PMID: 26197437] (Bioassay, Human) |
Bioassay |
Human |
Chiang N, Dalli J, Colas R, Serhan C Identification of resolvin D2 receptor mediating resolution of infections and organ protection. J Exp Med, 2015-07-20;212(8):1203-17. 2015-07-20 [PMID: 26195725] (Bioassay, Human) |
Bioassay |
Human |
Eigenbrod T, Pelka K, Latz E, Kreikemeyer B, Dalpke A TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes. J Immunol, 2015-06-22;195(3):1092-9. 2015-06-22 [PMID: 26101323] (Bioassay, Human) |
Bioassay |
Human |
Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma. J Transl Med, 2015-06-20;13(0):197. 2015-06-20 [PMID: 26088750] (Bioassay, Human) |
Bioassay |
Human |
Ptaschinski C, Mukherjee S, Moore M, Albert M, Helin K, Kunkel S, Lukacs N RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo. PLoS Pathog, 2015-06-17;11(6):e1004978. 2015-06-17 [PMID: 26083387] (Bioassay, Human) |
Bioassay |
Human |
Rossi O, Khan M, Schwarzer M, Hudcovic T, Srutkova D, Duncan S, Stolte E, Kozakova H, Flint H, Samsom J, Harmsen H, Wells J Faecalibacterium prausnitzii Strain HTF-F and Its Extracellular Polymeric Matrix Attenuate Clinical Parameters in DSS-Induced Colitis. PLoS ONE, 2015-04-24;10(4):e0123013. 2015-04-24 [PMID: 25910186] (Bioassay, Human) |
Bioassay |
Human |
Dutta D, Potnis P, Rhodes K, Wood S Wear particles derived from metal hip implants induce the generation of multinucleated giant cells in a 3-dimensional peripheral tissue-equivalent model. PLoS ONE, 2015-04-20;10(4):e0124389. 2015-04-20 [PMID: 25894745] (Bioassay, Human) |
Bioassay |
Human |
Florsheim E, Yu S, Bragatto I, Faustino L, Gomes E, Ramos R, Barbuto J, Medzhitov R, Russo M Integrated innate mechanisms involved in airway allergic inflammation to the serine protease subtilisin. J Immunol, 2015-04-15;194(10):4621-30. 2015-04-15 [PMID: 25876764] (Bioassay, Human) |
Bioassay |
Human |
Martner A, Wiktorin H, Lenox B, Ewald Sander F, Aydin E, Aurelius J, Thoren F, Stahlberg A, Hermodsson S, Hellstrand K Histamine promotes the development of monocyte-derived dendritic cells and reduces tumor growth by targeting the myeloid NADPH oxidase. J Immunol, 2015-04-13;194(10):5014-21. 2015-04-13 [PMID: 25870245] (Bioassay, Human) |
Bioassay |
Human |
Baharom F, Thomas S, Bieder A, Hellmer M, Volz J, Sandgren K, McInerney G, Karlsson Hedestam G, Mellman I, Smed-Sorensen A Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. J Immunol, 2015-03-23;194(9):4422-30. 2015-03-23 [PMID: 25801434] (Bioassay, Human) |
Bioassay |
Human |
Irvin S, Herold B Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk. PLoS ONE, 2015-03-23;10(3):e0121135. 2015-03-23 [PMID: 25798593] (Bioassay, Human) |
Bioassay |
Human |
Fernandes R, Bachiega T, Rodrigues D, Golim M, Dias-Melicio L, Balderramas H, Kaneno R, Soares A Paracoccidioides brasiliensis interferes on dendritic cells maturation by inhibiting PGE2 production. PLoS ONE, 2015-03-20;10(3):e0120948. 2015-03-20 [PMID: 25793979] (Bioassay, Human) |
Bioassay |
Human |
Dyer , Kimberly, Rosenberg , Helene F Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24). PLoS ONE, 2015-03-16;10(3):e0118887. 2015-03-16 [PMID: 25774667] (Bioassay, Human) |
Bioassay |
Human |
Zafra M, Canas J, Mazzeo C, Gamez C, Sanz V, Fernandez-Nieto M, Quirce S, Barranco P, Ruiz-Hornillos J, Sastre J, del Pozo V SOCS3 silencing attenuates eosinophil functions in asthma patients. Int J Mol Sci, 2015-03-10;16(3):5434-51. 2015-03-10 [PMID: 25764157] (Bioassay, Human) |
Bioassay |
Human |
Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, Macary P, Leo Y, Wong S, Puan K, Wong S Type I IFNs and IL-18 regulate the antiviral response of primary human gammadelta T cells against dendritic cells infected with Dengue virus. J Immunol, 2015-03-02;194(8):3890-900. 2015-03-02 [PMID: 25732728] (Bioassay, Human) |
Bioassay |
Human |
Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, Lu Y, Zhang Z, Liu H, Wang X, Wang R, Chu Y, Yang R Dendritic cell SIRT1-HIF1alpha axis programs the differentiation of CD4+ T cells through IL-12 and TGF-beta1. Proc Natl Acad Sci U S A, 2015-02-17;112(9):E957-65. 2015-02-17 [PMID: 25730867] (Bioassay, Human) |
Bioassay |
Human |
Martin , Kayleigh, Muessel , Michelle, Pullar , Christin, Willars , Gary B, Wardlaw , Andrew J The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels. PLoS ONE, 2015-02-06;10(2):e0116250. 2015-02-06 [PMID: 25659107] (Bioassay, Human) |
Bioassay |
Human |
Myster F, Palmeira L, Sorel O, Bouillenne F, DePauw E, Schwartz-Cornil I, Vanderplasschen A, Dewals B Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever. J Virol, 2015-01-14;89(7):3630-47. 2015-01-14 [PMID: 25589653] (Bioassay, Rabbit) |
Bioassay |
Rabbit |
Purushothaman P, Thakker S, Verma S Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells. J Virol, 2014-12-31;89(6):3093-111. 2014-12-31 [PMID: 25552714] (Bioassay, Human) |
Bioassay |
Human |
Zaccard C, Watkins S, Kalinski P, Fecek R, Yates A, Salter R, Ayyavoo V, Rinaldo C, Mailliard R CD40L induces functional tunneling nanotube networks exclusively in dendritic cells programmed by mediators of type 1 immunity. J Immunol, 2014-12-29;194(3):1047-56. 2014-12-29 [PMID: 25548234] (Bioassay, Human) |
Bioassay |
Human |
Rycaj K, Plummer J, Yin B, Li M, Garza J, Radvanyi L, Ramondetta L, Lin K, Johanning G, Tang D, Wang-Johanning F Cytotoxicity of human endogenous retrovirus K-specific T cells toward autologous ovarian cancer cells. Clin Cancer Res, 2014-11-04;21(2):471-83. 2014-11-04 [PMID: 25370465] (Bioassay, Human) |
Bioassay |
Human |
Gallagher K, Joshi A, Carson W, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman E, Henke P, Hogaboam C, Burant C, Kunkel S Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes. Diabetes, 2014-11-03;64(4):1420-30. 2014-11-03 [PMID: 25368099] (Bioassay, Human) |
Bioassay |
Human |
Lam , Sharon, Sung , Julia, Cruz , Conrad, Castillo-Caro , Paul, Ngo , Minhtran, Garrido , Carolina, Kuruc , Joann, Archin , Nancie, Rooney , Cliona, Margolis , David, Bollard , Catherin Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Mol Ther, 2014-11-04;23(2):387-95. 2014-11-04 [PMID: 25366030] (Bioassay, Human) |
Bioassay |
Human |
Rahmati M, Petitbarat M, Dubanchet S, Bensussan A, Chaouat G, Ledee N Granulocyte-Colony Stimulating Factor related pathways tested on an endometrial ex-vivo model. PLoS ONE, 2014-10-02;9(9):e102286. 2014-10-02 [PMID: 25275446] (Bioassay, Human) |
Bioassay |
Human |
Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, Wei Y, Ouyang F, Chen D, Wu Y, Lao X, Deng H, Zheng L B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest, 2014-09-17;124(10):4657-67. 2014-09-17 [PMID: 25244097] (Bioassay, Human) |
Bioassay |
Human |
Bates J, Flanagan K, Mo L, Ota N, Ding J, Ho S, Liu S, Roose-Girma M, Warming S, Diehl L Dendritic cell CD83 homotypic interactions regulate inflammation and promote mucosal homeostasis. Mucosal Immunol, 2014-09-10;8(2):414-28. 2014-09-10 [PMID: 25204675] (Bioassay, Human) |
Bioassay |
Human |
Hedl M, Abraham C A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1. Proc Natl Acad Sci U S A, 2014-09-02;111(37):13451-6. 2014-09-02 [PMID: 25197060] (Bioassay, Human) |
Bioassay |
Human |
Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE, 2014-09-03;9(9):e106673. 2014-09-03 [PMID: 25184791] (Bioassay, Human) |
Bioassay |
Human |
Samikkannu T, Rao K, Ding H, Agudelo M, Raymond A, Yoo C, Nair M Immunopathogenesis of HIV infection in cocaine users: role of arachidonic acid. PLoS ONE, 2014-08-29;9(8):e106348. 2014-08-29 [PMID: 25171226] (Cell Culture, Human) |
Cell Culture |
Human |
Anderson J, Titz B, Akiyama R, Komisopoulou E, Park A, Tap W, Graeber T, Denny C Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Mol Cancer Res, 2014-08-04;12(12):1740-54. 2014-08-04 [PMID: 25092916] (Bioassay, Human) |
Bioassay |
Human |
King T, Kemmler C, Guo Z, Mann D, Lu Y, Coeshott C, Gehring A, Bertoletti A, Ho Z, Delaney W, Gaggar A, Subramanian G, McHutchison J, Shrivastava S, Lee Y, Kottilil S, Bellgrau D, Rodell T, Apelian D A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearance. PLoS ONE, 2014-07-22;9(7):e101904. 2014-07-22 [PMID: 25051027] (Stimulation, Human) |
Stimulation |
Human |
Deng B, Wang C, Arnardottir H, Li Y, Cheng C, Dalli J, Serhan C Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. PLoS ONE, 2014-07-18;9(7):e102362. 2014-07-18 [PMID: 25036362] (Bioassay, Human) |
Bioassay |
Human |
Schiavoni I, Fedele G, Quattrini A, Bianco M, Schnoeller C, Openshaw P, Locht C, Ausiello C Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses. PLoS ONE, 2014-06-26;9(6):e100166. 2014-06-26 [PMID: 24967823] (Bioassay, Human) |
Bioassay |
Human |
Smith K, Mailliard R, Larsen B, Wong K, Gupta P, Mullins J, Rinaldo C Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1. J Virol, 2014-06-18;88(17):9976-90. 2014-06-18 [PMID: 24942586] (Bioassay, Human) |
Bioassay |
Human |
McCauley L, Dalli J, Koh A, Chiang N, Serhan C Cutting edge: Parathyroid hormone facilitates macrophage efferocytosis in bone marrow via proresolving mediators resolvin D1 and resolvin D2. J Immunol, 2014-06-02;193(1):26-9. 2014-06-02 [PMID: 24890726] (Bioassay, Human) |
Bioassay |
Human |
Hedl M, Zheng S, Abraham C The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. J Immunol, 2014-05-19;192(12):5924-32. 2014-05-19 [PMID: 24842757] (Bioassay, Human) |
Bioassay |
Human |
Ohgidani , Masahiro, Kato , Takahiro, Setoyama , Daiki, Sagata , Noriaki, Hashimoto , Ryota, Shigenobu , Kazue, Yoshida , Tetsuhik, Hayakawa , Kohei, Shimokawa , Norihiro, Miura , Daisuke, Utsumi , Hideo, Kanba , Shigenob Direct induction of ramified microglia-like cells from human monocytes: dynamic microglial dysfunction in Nasu-Hakola disease. Sci Rep, 2014-05-14;4(0):4957. 2014-05-14 [PMID: 24825127] (Bioassay, Human) |
Bioassay |
Human |
Piazza P, Campbell D, Marques E, Hildebrand W, Buchli R, Mailliard R, Rinaldo C Dengue virus-infected human dendritic cells reveal hierarchies of naturally expressed novel NS3 CD8 T cell epitopes. Clin Exp Immunol, 2014-09-01;177(3):696-702. 2014-09-01 [PMID: 24816171] (Bioassay, Human) |
Bioassay |
Human |
Moreno-Nieves U, Didier C, Levy Y, Barre-Sinoussi F, Scott-Algara D NK cells are primed by ANRS MVA(HIV)-infected DCs, via a mechanism involving NKG2D and membrane-bound IL-15, to control HIV-1 infection in CD4+ T cells. Eur J Immunol, 2014-06-24;44(8):2370-9. 2014-06-24 [PMID: 24777763] (Bioassay, Human) |
Bioassay |
Human |
Qeska V, Barthel Y, Herder V, Stein V, Tipold A, Urhausen C, Gunzel-Apel A, Rohn K, Baumgartner W, Beineke A Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription. PLoS ONE, 2014-04-25;9(4):e96121. 2014-04-25 [PMID: 24769532] (Bioassay, Canine) |
Bioassay |
Canine |
Wallner S, Grandl M, Konovalova T, Sigruner A, Kopf T, Peer M, Orso E, Liebisch G, Schmitz G Monocyte to macrophage differentiation goes along with modulation of the plasmalogen pattern through transcriptional regulation. PLoS ONE, 2014-04-08;9(4):e94102. 2014-04-08 [PMID: 24714687] (Bioassay, Human) |
Bioassay |
Human |
Olivetta E, Tirelli V, Chiozzini C, Scazzocchio B, Romano I, Arenaccio C, Sanchez M HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation. PLoS ONE, 2014-04-04;9(4):e93699. 2014-04-04 [PMID: 24705461] (Bioassay, Human) |
Bioassay |
Human |
Buttari B, Profumo E, Domenici G, Tagliani A, Ippoliti F, Bonini S, Businaro R, Elenkov I, Rigano R Neuropeptide Y induces potent migration of human immature dendritic cells and promotes a Th2 polarization. FASEB J, 2014-04-03;28(7):3038-49. 2014-04-03 [PMID: 24699455] (Cell Culture, Human) |
Cell Culture |
Human |
Picco G, Beatson R, Taylor-Papadimitriou J, Burchell J Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas. Eur J Immunol, 2014-04-17;44(7):1947-55. 2014-04-17 [PMID: 24648154] (Bioassay, Human) |
Bioassay |
Human |
Saijo , Tomomi, Chen , Jianghan, Chen , Sharon C, Rosen , Lindsey, Yi , Jin, Sorrell , Tania C, Bennett , John E, Holland , Steven M, Browne , Sarah K, Kwon-Chung , Kyung J Anti-granulocyte-macrophage colony-stimulating factor autoantibodies are a risk factor for central nervous system infection by Cryptococcus gattii in otherwise immunocompetent patients. MBio, 2014-03-18;5(2):e00912-14. 2014-03-18 [PMID: 24643864] (Bioassay, Human) |
Bioassay |
Human |
Harris K, Ramachandran G, Basu S, Rollins S, Mann D, Cross A The IL-23/Th17 axis is involved in the adaptive immune response to Bacillus anthracis in humans. Eur J Immunol, 2014-01-02;44(3):752-62. 2014-01-02 [PMID: 24643777] (Bioassay, Human) |
Bioassay |
Human |
Umashankar , Mahadeva, Rak , Michael, Bughio , Farah, Zagallo , Patricia, Caviness , Katie, Goodrum , Felicia Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection. J Virol, 2014-03-12;88(11):5987-6002. 2014-03-12 [PMID: 24623432] (Bioassay, Human) |
Bioassay |
Human |
Ren X, Ma L, Liu Q, Li C, Huang Z, Wu L, Xiong S, Wang J, Wang H The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection. Virol J, 2014-03-12;11(0):47. 2014-03-12 [PMID: 24620896] (Bioassay, Human) |
Bioassay |
Human |
Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure. PLoS ONE, 2014-02-14;9(2):e88714. 2014-02-14 [PMID: 24551140] (Bioassay, Human) |
Bioassay |
Human |
Leskowitz , R, Fogg , M H, Zhou , X Y, Kaur , A, Silveira , E L V, Villinger , F, Lieberman , P M, Wang , F, Ertl , H C Adenovirus-based vaccines against rhesus lymphocryptovirus EBNA-1 induce expansion of specific CD8+ and CD4+ T cells in persistently infected rhesus macaques. J Virol, 2014-02-12;88(9):4721-35. 2014-02-12 [PMID: 24522914] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
Herath S, Benlahrech A, Papagatsias T, Athanasopoulos T, Bouzeboudjen Z, Hervouet C, Klavinskis L, Meiser A, Kelleher P, Dickson G, Patterson S Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses. PLoS ONE, 2014-02-05;9(2):e88327. 2014-02-05 [PMID: 24505475] (Bioassay, Human) |
Bioassay |
Human |
Han , Ji Eun, Wui , Seo Ri, Kim , Kwang Su, Cho , Yang Je, Cho , Wan Je, Lee , Na Gyong Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide. PLoS ONE, 2014-01-22;9(1):e85838. 2014-01-22 [PMID: 24465739] (Bioassay, Human) |
Bioassay |
Human |
Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension. J Exp Med, 2014-01-20;211(2):263-80. 2014-01-20 [PMID: 24446489] (In Vivo, Mouse) |
In Vivo |
Mouse |
Garcia S, Krausz S, Ambarus C, Fernandez B, Hartkamp L, van Es I, Hamann J, Baeten D, Tak P, Reedquist K Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype. PLoS ONE, 2014-01-03;9(1):e82088. 2014-01-03 [PMID: 24404127] (Bioassay, Human) |
Bioassay |
Human |
Napuri , Jessica, Pilakka-Kanthikeel , Sudheesh, Raymond , Andrea, Agudelo , Marisela, Yndart-Arias , Adriana, Saxena , Shailend, Nair , Madhavan Cocaine enhances HIV-1 infectivity in monocyte derived dendritic cells by suppressing microRNA-155. PLoS ONE, 2013-12-31;8(12):e83682. 2013-12-31 [PMID: 24391808] (Bioassay, Human) |
Bioassay |
Human |
Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18. PLoS ONE, 2013-12-20;8(12):e82586. 2013-12-20 [PMID: 24376549] (Bioassay, Human) |
Bioassay |
Human |
Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, Hussein K, Zeidler C, Welte K, Skokowa J A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation. Blood, 2013-12-18;123(8):1239-49. 2013-12-18 [PMID: 24352879] (Bioassay, Human) |
Bioassay |
Human |
Cheng X, He P, Lee T, Yao H, Li R, Shen Y High activities of BACE1 in brains with mild cognitive impairment. Am J Pathol, 2014-01-01;184(1):141-7. 2014-01-01 [PMID: 24332014] (Bioassay, Human) |
Bioassay |
Human |
Sharquie I, Al-Ghouleh A, Fitton P, Clark M, Armour K, Sewell H, Shakib F, Ghaemmaghami A An investigation into IgE-facilitated allergen recognition and presentation by human dendritic cells. BMC Immunol, 2013-12-13;14(0):54. 2013-12-13 [PMID: 24330349] (Bioassay, Human) |
Bioassay |
Human |
Osaki Y, Yokohama A, Saito A, Tahara K, Yanagisawa K, Ogawa Y, Ishizaki T, Mitsui T, Koiso H, Takizawa M, Uchiumi H, Saitoh T, Handa H, Murakami H, Tsukamoto N, Nojima Y Characterization of CD56+ dendritic-like cells: a normal counterpart of blastic plasmacytoid dendritic cell neoplasm? PLoS ONE, 2013-11-29;8(11):e81722. 2013-11-29 [PMID: 24312342] (Cell Culture, Human) |
Cell Culture |
Human |
Van Cor-Hosmer S, Kim D, Daly M, Daddacha W, Kim B Restricted 5'-end gap repair of HIV-1 integration due to limited cellular dNTP concentrations in human primary macrophages. J Biol Chem, 2013-10-04;288(46):33253-62. 2013-10-04 [PMID: 24097986] (Bioassay, Human) |
Bioassay |
Human |
Marwick , John A, Dorward , David A, Lucas , Christop, Jones , Katie O, Sheldrake , Tara A, Fox , Sarah, Ward , Carol, Murray , Joanna, Brittan , Mairi, Hirani , Nik, Duffin , Rodger, Dransfield , Ian, Haslett , Christop, Rossi , Adriano Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments. J Leukoc Biol, 2013-08-20;94(6):1285-92. 2013-08-20 [PMID: 23964116] (Bioassay, Human) |
Bioassay |
Human |
Einwallner E, Jaeger E, Mitterbauer-Hohendanner G, Bilban M, Simonitsch-Klupp I, Steiner I, Pernicka E, Hoermann G, Herndlhofer S, Sillaber C, Valent P, Schwarzinger I Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib. Stem Cells Dev, 2013-09-04;22(23):3043-51. 2013-09-04 [PMID: 23883175] (Bioassay, Human) |
Bioassay |
Human |
Quintino L, Manfre G, Wettergren E, Namislo A, Isaksson C, Lundberg C Functional neuroprotection and efficient regulation of GDNF using destabilizing domains in a rodent model of Parkinson's disease. Mol Ther, 2013-07-24;21(12):2169-80. 2013-07-24 [PMID: 23881415] (Bioassay, Human) |
Bioassay |
Human |
Spiess C, Bevers J, Jackman J, Chiang N, Nakamura G, Dillon M, Liu H, Molina P, Elliott J, Shatz W, Scheer J, Giese G, Persson J, Zhang Y, Dennis M, Giulianotti J, Gupta P, Reilly D, Palma E, Wang J, Stefanich E, Scheerens H, Fuh G, Wu L Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines. J Biol Chem, 2013-07-23;288(37):26583-93. 2013-07-23 [PMID: 23880771] (Bioassay, Human) |
Bioassay |
Human |
Rodrigues R, Grosso A, Moita L Genome-wide analysis of alternative splicing during dendritic cell response to a bacterial challenge. PLoS ONE, 2013-04-17;8(4):e61975. 2013-04-17 [PMID: 23613991] (Bioassay, Human) |
Bioassay |
Human |
Wang S, Chen Z, Hu C, Qian F, Cheng Y, Wu M, Shi B, Chen J, Hu Y, Yuan Z Hepatitis B virus surface antigen selectively inhibits TLR2 ligand-induced IL-12 production in monocytes/macrophages by interfering with JNK activation. J Immunol, 2013-04-12;190(10):5142-51. 2013-04-12 [PMID: 23585678] (Bioassay, Human) |
Bioassay |
Human |
Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume M, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease. Immunology, 2013-05-01;139(1):19-29. 2013-05-01 [PMID: 23566200] (Bioassay, Human) |
Bioassay |
Human |
Reading J, Yang J, Sabbah S, Skowera A, Knight R, Pinxteren J, Vaes B, Allsopp T, Ting A, Busch S, Raber A, Deans R, Tree T Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity. J Immunol, 2013-04-01;190(9):4542-52. 2013-04-01 [PMID: 23547116] (Bioassay, Human) |
Bioassay |
Human |
Nixon , Briana, Stefanidou , Martha, Mesquita , Pedro M, Fakioglu , Esra, Segarra , Theodore, Rohan , Lisa, Halford , William, Palmer , Kenneth, Herold , Betsy C Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. J Virol, 2013-03-27;87(11):6257-69. 2013-03-27 [PMID: 23536670] (Bioassay, Human) |
Bioassay |
Human |
Chen , Qian, Swaminathan , Sanjay, Yang , De, Dai , Lue, Sui , Hongyan, Yang , Jun, Hornung , Ronald L, Wang , Yanmei, Huang , Da Wei, Hu , Xiaojun, Lempicki , Richard, Imamichi , Tomozumi Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway. PLoS ONE, 2013-03-20;8(3):e59194. 2013-03-20 [PMID: 23527130] (Bioassay, Human) |
Bioassay |
Human |
Madsen J, Gaiha G, Palaniyar N, Dong T, Mitchell D, Clark H Surfactant Protein D modulates HIV infection of both T-cells and dendritic cells. PLoS ONE, 2013-03-18;8(3):e59047. 2013-03-18 [PMID: 23527085] (Bioassay, Human) |
Bioassay |
Human |
Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J Immunol, 2013-03-18;190(8):3959-66. 2013-03-18 [PMID: 23509356] (Bioassay, Human) |
Bioassay |
Human |
Dalli J, Zhu M, Vlasenko N, Deng B, Haeggstrom J, Petasis N, Serhan C The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. FASEB J, 2013-03-15;27(7):2573-83. 2013-03-15 [PMID: 23504711] (Bioassay, Human) |
Bioassay |
Human |
Yu , Jianhua, Peng , Yong, Wu , Lai-Chu, Xie , Zhiliang, Deng , Youcai, Hughes , Tiffany, He , Shun, Mo , XiaoKui, Chiu , Ming, Wang , Qi-En, He , Xiaoming, Liu , Shujun, Grever , Michael, Chan , Kenneth, Liu , Zhongfa Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. PLoS ONE, 2013-02-13;8(2):e55934. 2013-02-13 [PMID: 23457487] (Bioassay, Human) |
Bioassay |
Human |
Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, Lopez-Albaitero A, Gibson S, Gooding W, Ferrone S, Ferris R Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients. Clin Cancer Res, 2013-02-26;19(7):1858-72. 2013-02-26 [PMID: 23444227] (Bioassay, Human) |
Bioassay |
Human |
Dong J, Chang H, Ivascu C, Qian Y, Rezai S, Okhrimenko A, Cosmi L, Maggi L, Eckhardt F, Wu P, Sieper J, Alexander T, Annunziato F, Gossen M, Li J, Radbruch A, Thiel A Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes. Eur J Immunol, 2013-03-01;43(3):793-804. 2013-03-01 [PMID: 23255246] (Bioassay, Human) |
Bioassay |
Human |
Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med, 2012-12-02;19(1):57-64. 2012-12-02 [PMID: 23202296] (Cell Culture, Human) |
Cell Culture |
Human |
Brusic , Ana, Hainz , Ursula, Wadleigh , Martha, Neuberg , Donna, Su , Mei, Canning , Christin, Deangelo , Daniel J, Stone , Richard, Lee , Jeng-Shi, Mulligan , Richard, Ritz , Jerome, Dranoff , Glenn, Sasada , Tetsuro, Wu , Catherin Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients. Oncoimmunology, 2012-10-01;1(7):1095-1103. 2012-10-01 [PMID: 23170257] (Bioassay, Human) |
Bioassay |
Human |
Selleri S, Dieng M, Nicoletti S, Louis I, Beausejour C, Le Deist F, Haddad E Cord-blood-derived mesenchymal stromal cells downmodulate CD4+ T-cell activation by inducing IL-10-producing Th1 cells. Stem Cells Dev, 2013-01-04;22(7):1063-75. 2013-01-04 [PMID: 23167734] (Bioassay, Human) |
Bioassay |
Human |
Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas. J. Invest. Dermatol., 2012-06-21;132(11):2642-51. 2012-06-21 [PMID: 22718118] (Bioassay, Human) |
Bioassay |
Human |
Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase. J. Biol. Chem., 2012-06-11;287(31):25964-74. 2012-06-11 [PMID: 22689578] (Bioassay, Human) |
Bioassay |
Human |
CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates. Eur. J. Immunol., 2012-07-04;42(8):2019-30. 2012-07-04 [PMID: 22585548] (Bioassay, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)) |
Bioassay |
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque) |
Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. Eur. J. Immunol., 2012-04-01;42(4):936-45. 2012-04-01 [PMID: 22531918] (Bioassay, Human) |
Bioassay |
Human |
Figueiredo AB, Serafim TD, Marques-da-Silva EA, Meyer-Fernandes JR, Afonso LC Leishmania amazonensis impairs DC function by inhibiting CD40 expression via A2B adenosine receptor activation. Eur. J. Immunol., 2012-05-01;42(5):1203-15. 2012-05-01 [PMID: 22311598] (Bioassay, Mouse) |
Bioassay |
Mouse |
Kawamura T, Ogawa Y, Nakamura Y Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency. J. Clin. Invest., 2012-01-03;122(2):722-32. 2012-01-03 [PMID: 22214844] (Bioassay, Human) |
Bioassay |
Human |
Emara M, Royer PJ, Mahdavi J Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite. J. Biol. Chem., 2011-12-28;287(8):5756-63. 2011-12-28 [PMID: 22205703] (Bioassay, Human) |
Bioassay |
Human |
Kessler C, Greindl A, Breuer B, Haberl U, Rybka A, Emgenbroich M, Frank HG, Potgens AJ Erythropoietin mimetic compound AGEM400(HES) binds to the same receptor as erythropoietin but displays a different spectrum of activities. Cytokine, 2011-12-03;57(2):226-37. 2011-12-03 [PMID: 22142701] (Bioassay, Human) |
Bioassay |
Human |
Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia, 2010-11-19;25(1):161-8. 2010-11-19 [PMID: 21102427] (Bioassay, Human) |
Bioassay |
Human |
Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies. J. Virol., 2010-11-17;85(2):1077-85. 2010-11-17 [PMID: 21084491] (Bioassay, Human) |
Bioassay |
Human |
Xu H, Wang X, Pahar B Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression. J. Immunol., 2010-11-08;185(12):7340-8. 2010-11-08 [PMID: 21059890] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
Zhang HH, Song K, Rabin RL, Hill BJ, Perfetto SP, Roederer M, Douek DC, Siegel RM, Farber JM CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. J. Immunol., 2010-10-27;185(11):6646-63. 2010-10-27 [PMID: 20980630] (Bioassay, Human) |
Bioassay |
Human |
Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW Dynamic interaction networks in a hierarchically organized tissue. Mol. Syst. Biol., 2010-10-05;6(0):417. 2010-10-05 [PMID: 20924352] (Bioassay, Human) |
Bioassay |
Human |
Johnson LA, Jackson DG Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration. Int. Immunol., 2010-08-25;22(10):839-49. 2010-08-25 [PMID: 20739459] (Bioassay, Human) |
Bioassay |
Human |
Pietila TE, Latvala S, Osterlund P, Julkunen I Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human monocyte-derived DCs. J. Leukoc. Biol., 2010-07-07;88(4):665-74. 2010-07-07 [PMID: 20610797] (Bioassay, Human) |
Bioassay |
Human |
Ghirelli C, Zollinger R, Soumelis V Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. Blood, 2010-04-09;115(24):5037-40. 2010-04-09 [PMID: 20382843] (Bioassay, Human) |
Bioassay |
Human |
Ha CT, Wu JA, Irmak S, Lisboa FA, Dizon AM, Warren JW, Ergun S, Dveksler GS Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis. Biol. Reprod., 2010-03-24;83(1):27-35. 2010-03-24 [PMID: 20335639] (Bioassay, Human) |
Bioassay |
Human |
Zheng X, Ma P, De Paiva CS, Cunningham MA, Hwang CS, Pflugfelder SC, Li DQ TSLP and downstream molecules in experimental mouse allergic conjunctivitis. Invest. Ophthalmol. Vis. Sci., 2010-01-27;51(6):3076-82. 2010-01-27 [PMID: 20107175] (Bioassay, Human) |
Bioassay |
Human |
Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property. J. Immunol., 2009-12-15;183(12):8176-85. 2009-12-15 [PMID: 20007583] (Cell Culture, Human) |
Cell Culture |
Human |
Correale J, Farez M Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms. J. Immunol., 2009-10-07;183(9):5999-6012. 2009-10-07 [PMID: 19812189] (Bioassay, Human) |
Bioassay |
Human |
Puxeddu I, Berkman N, Ribatti D Osteopontin is expressed and functional in human eosinophils. Allergy, 2009-10-05;65(2):168-74. 2009-10-05 [PMID: 19804447] (Bioassay, Human) |
Bioassay |
Human |
Duraisingham SS, Hornig J, Gotch F, Patterson S TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses. J. Immunol., 2009-07-22;183(4):2242-51. 2009-07-22 [PMID: 19625644] (Bioassay, Human) |
Bioassay |
Human |
Furukawa M, Takaishi H, Takito J, Yoda M, Sakai S, Hikata T, Hakozaki A, Uchikawa S, Matsumoto M, Chiba K, Kimura T, Okada Y, Matsuo K, Yoshida H, Toyama Y IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos. J. Immunol., 2009-07-20;183(4):2397-406. 2009-07-20 [PMID: 19620301] (Bioassay, Human) |
Bioassay |
Human |
Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J. Immunol., 2009-07-10;183(3):1739-50. 2009-07-10 [PMID: 19592653] (Bioassay, Human) |
Bioassay |
Human |
Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur. J. Immunol., 2009-05-01;39(5):1221-30. 2009-05-01 [PMID: 19350551] (Bioassay, Human) |
Bioassay |
Human |
Ogawa Y, Kawamura T, Kimura T, Ito M, Blauvelt A, Shimada S Gram-positive bacteria enhance HIV-1 susceptibility in Langerhans cells, but not in dendritic cells, via Toll-like receptor activation. Blood, 2009-03-11;113(21):5157-66. 2009-03-11 [PMID: 19279330] (Bioassay, Human) |
Bioassay |
Human |
McAulay KA, Haque T, Urquhart G, Bellamy C, Guiretti D, Crawford DH Epitope specificity and clonality of EBV-specific CTLs used to treat posttransplant lymphoproliferative disease. J. Immunol., 2009-03-15;182(6):3892-901. 2009-03-15 [PMID: 19265169] (Bioassay, Human) |
Bioassay |
Human |
Saulle E, Riccioni R, Coppola S, Parolini I, Diverio D, Riti V, Mariani G, Laufer S, Sargiacomo M, Testa U Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation. Br. J. Haematol., 2009-02-24;145(3):399-411. 2009-02-24 [PMID: 19245429] (Bioassay, Human) |
Bioassay |
Human |
Margulis A, Nocka KH, Wood NL, Wolf SF, Goldman SJ, Kasaian MT MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice. Am. J. Physiol. Lung Cell Mol. Physiol., 2008-12-05;296(2):L236-47. 2008-12-05 [PMID: 19060229] (Bioassay, Human) |
Bioassay |
Human |
Schnickmann S, Camacho-Trullio D, Bissinger M, Eils R, Angel P, Schirmacher P, Szabowski A, Breuhahn K AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor. J. Invest. Dermatol., 2008-11-20;129(5):1140-8. 2008-11-20 [PMID: 19020551] (Bioassay, Human) |
Bioassay |
Human |
Rahmoun M, Moles JP, Pedretti N, Mathieu M, Fremaux I, Raison-Peyron N, Lecron JC, Yssel H, Pene J Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. J. Invest. Dermatol., 2008-10-09;129(3):671-81. 2008-10-09 [PMID: 18843289] (Bioassay, Human) |
Bioassay |
Human |
Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM Adenosine receptors in regulation of dendritic cell differentiation and function. Blood, 2008-06-17;112(5):1822-31. 2008-06-17 [PMID: 18559975] (Bioassay, Human) |
Bioassay |
Human |
Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J. Allergy Clin. Immunol., 2008-06-01;121(6):1484-90. 2008-06-01 [PMID: 18539196] (Bioassay, Human) |
Bioassay |
Human |
Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp. Hematol., 2008-05-27;36(8):1035-46. 2008-05-27 [PMID: 18504067] (Bioassay, Human) |
Bioassay |
Human |
Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. J. Immunol., 2008-05-01;180(9):6000-9. 2008-05-01 [PMID: 18424720] (Bioassay, Human) |
Bioassay |
Human |
Chamoux E, Houde N, L'Eriger K, Roux S Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL pathway. J. Cell. Physiol., 2008-08-01;216(2):536-42. 2008-08-01 [PMID: 18338379] (Bioassay, Human) |
Bioassay |
Human |
Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J. Leukoc. Biol., 2008-02-15;83(5):1181-93. 2008-02-15 [PMID: 18281438] (Bioassay, Human) |
Bioassay |
Human |
Huang SJ, Chen CP, Schatz F, Rahman M, Abrahams VM, Lockwood CJ Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua. J. Pathol., 2008-02-01;214(3):328-36. 2008-02-01 [PMID: 18069648] (Bioassay, Human) |
Bioassay |
Human |
Esnault S, Rosenthal LA, Shen ZJ, Sedgwick JB, Szakaly RJ, Sorkness RL, Malter JS A critical role for Pin1 in allergic pulmonary eosinophilia in rats. J. Allergy Clin. Immunol., 2007-08-27;120(5):1082-8. 2007-08-27 [PMID: 17720236] (Bioassay, Human) |
Bioassay |
Human |
Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques. Transplantation, 2007-07-27;84(2):196-206. 2007-07-27 [PMID: 17667811] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
Hartiala P, Hytonen J, Pelkonen J, Kimppa K, West A, Penttinen MA, Suhonen J, Lahesmaa R, Viljanen MK Transcriptional response of human dendritic cells to Borrelia garinii--defective CD38 and CCR7 expression detected. J. Leukoc. Biol., 2007-04-17;82(1):33-43. 2007-04-17 [PMID: 17440035] (Bioassay, Human) |
Bioassay |
Human |
Wang J, Zhang Y, Wei J, Zhang X, Zhang B, Zhu Z, Zou W, Wang Y, Mou Z, Ni B, Wu Y Lewis X oligosaccharides targeting to DC-SIGN enhanced antigen-specific immune response. Immunology, 2007-03-20;121(2):174-82. 2007-03-20 [PMID: 17371544] (Bioassay, Human) |
Bioassay |
Human |
Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 2007-02-01;25(2):490-9. 2007-02-01 [PMID: 17284653] (Bioassay, Rat) |
Bioassay |
Rat |
Kurooka M, Kaneda Y Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res., 2007-01-01;67(1):227-36. 2007-01-01 [PMID: 17210703] (Bioassay, Human) |
Bioassay |
Human |
Zhang R, Becnel L, Li M, Chen C, Yao Q C-reactive protein impairs human CD14+ monocyte-derived dendritic cell differentiation, maturation and function. Eur. J. Immunol., 2006-11-01;36(11):2993-3006. 2006-11-01 [PMID: 17051617] (Bioassay, Human) |
Bioassay |
Human |
Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. Exp. Hematol., 2006-10-01;34(10):1312-22. 2006-10-01 [PMID: 16982324] (Bioassay, Human) |
Bioassay |
Human |
Walker J, Tough DF Modification of TLR-induced activation of human dendritic cells by type I IFN: synergistic interaction with TLR4 but not TLR3 agonists. Eur. J. Immunol., 2006-07-01;36(7):1827-36. 2006-07-01 [PMID: 16783851] (Bioassay, Human) |
Bioassay |
Human |
Vaknin-Dembinsky A, Balashov K, Weiner HL IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J. Immunol., 2006-06-15;176(12):7768-74. 2006-06-15 [PMID: 16751425] (Bioassay, Human) |
Bioassay |
Human |
Ito M, Minamiya Y, Kawai H, Saito S, Saito H, Nakagawa T, Imai K, Hirokawa M, Ogawa J Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node. J. Immunol., 2006-05-01;176(9):5637-43. 2006-05-01 [PMID: 16622033] (Bioassay, Human) |
Bioassay |
Human |
Reed JA, Clegg DJ, Smith KB, Tolod-Richer EG, Matter EK, Picard LS, Seeley RJ GM-CSF action in the CNS decreases food intake and body weight. J. Clin. Invest., 2005-11-01;115(11):3035-44. 2005-11-01 [PMID: 16276414] (In Vivo, Rat) |
In Vivo |
Rat |
Hanley MB, Napolitano LA, McCune JM Growth hormone-induced stimulation of multilineage human hematopoiesis. Stem Cells, 2005-06-13;23(8):1170-9. 2005-06-13 [PMID: 15955828] (Bioassay, Human) |
Bioassay |
Human |
Roux S, Lambert-Comeau P, Saint-Pierre C, Lepine M, Sawan B, Parent JL Death receptors, Fas and TRAIL receptors, are involved in human osteoclast apoptosis. Biochem. Biophys. Res. Commun., 2005-07-22;333(1):42-50. 2005-07-22 [PMID: 15936719] (Bioassay, Human) |
Bioassay |
Human |
Takei M, Umeyama A, Arihara S, Matsumoto H Effect of piceatannol in human monocyte-derived dendritic cells in vitro. J Pharm Sci, 2005-05-01;94(5):974-82. 2005-05-01 [PMID: 15793803] (Bioassay, Human) |
Bioassay |
Human |
Yamamoto H, Nagata M, Sakamoto Y CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1. Ann. Allergy Asthma Immunol., 2005-02-01;94(2):292-300. 2005-02-01 [PMID: 15765748] (Bioassay, Human) |
Bioassay |
Human |
Pound JD, Batth BK, Johannessen I, Wood K Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma. J. Immunol., 2005-03-01;174(5):3015-23. 2005-03-01 [PMID: 15728515] (Bioassay, Human) |
Bioassay |
Human |
Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F Human peripheral blood eosinophils induce angiogenesis. Int. J. Biochem. Cell Biol., 2005-03-01;37(3):628-36. 2005-03-01 [PMID: 15618019] (Bioassay, Human) |
Bioassay |
Human |
Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity, 2004-12-01;21(6):831-42. 2004-12-01 [PMID: 15589171] (Bioassay, Human) |
Bioassay |
Human |
Godfrey WR, Spoden DJ, Ge YG, Baker SR, Liu B, Levine BL, June CH, Blazar BR, Porter SB Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood, 2004-09-16;105(2):750-8. 2004-09-16 [PMID: 15374887] (Bioassay, Human) |
Bioassay |
Human |
Nagineni CN, Kutty V, Detrick B, Hooks JJ Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol., 2005-04-01;203(1):35-43. 2005-04-01 [PMID: 15368539] (Bioassay, Human) |
Bioassay |
Human |
Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood, 2004-09-09;105(2):830-7. 2004-09-09 [PMID: 15358625] (Bioassay, Human) |
Bioassay |
Human |
Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients. J. Allergy Clin. Immunol., 2004-09-01;114(3):538-44. 2004-09-01 [PMID: 15356554] (Bioassay, Human) |
Bioassay |
Human |
Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human) |
Bioassay |
Human |
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Bioassay, Human) |
Bioassay |
Human |
Johansson MW, Lye MH, Barthel SR, Duffy AK, Annis DS, Mosher DF Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes. Am. J. Respir. Cell Mol. Biol., 2004-06-25;31(4):413-22. 2004-06-25 [PMID: 15220135] (Bioassay, Human) |
Bioassay |
Human |
Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells. Immunology, 2004-06-01;112(2):274-89. 2004-06-01 [PMID: 15147571] (Bioassay, Human) |
Bioassay |
Human |
Godfrey WR, Ge YG, Spoden DJ, Levine BL, June CH, Blazar BR, Porter SB In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood, 2004-03-18;104(2):453-61. 2004-03-18 [PMID: 15031211] (Bioassay, Human) |
Bioassay |
Human |
Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem. J., 2004-06-01;380(0):425-33. 2004-06-01 [PMID: 14992689] (Bioassay, Human) |
Bioassay |
Human |
Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood, 2003-09-25;103(3):1089-98. 2003-09-25 [PMID: 14512323] (SDS-Page, Human) |
SDS-Page |
Human |
Hellman C, 107334, Hallden G, Hylander B, Lundahl J Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects. Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling, 2003-01-01;131(1):75-81. 2003-01-01 [PMID: 12519389] (Bioassay, Human) |
Bioassay |
Human |
Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B, Neyrolles O DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J. Exp. Med., 2003-01-06;197(1):121-7. 2003-01-06 [PMID: 12515819] (Bioassay, Human) |
Bioassay |
Human |
Manz MG, 107325, Miyamoto T, Akashi K, Weissman IL Prospective isolation of human clonogenic common myeloid progenitors. Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases, 2002-08-22;99(18):11872-7. 2002-08-22 [PMID: 12193648] (Bioassay, Human) |
Bioassay |
Human |
Schmid-Grendelmeier P, Altznauer F, Fischer B, Bizer C, Straumann A, Menz G, Blaser K, Wuthrich B, Simon HU Eosinophils express functional IL-13 in eosinophilic inflammatory diseases. J. Immunol., 2002-07-15;169(2):1021-7. 2002-07-15 [PMID: 12097410] (Bioassay, Human) |
Bioassay |
Human |
Edgeworth JD, Spencer J, Phalipon A, Griffin GE, Sansonetti PJ Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur. J. Immunol., 2002-05-01;32(5):1464-71. 2002-05-01 [PMID: 11981835] (Bioassay, Human) |
Bioassay |
Human |
Wu L, 107253, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in Sweden, 2002-01-29;99(3):1568-73. 2002-01-29 [PMID: 11818554] (Bioassay, Human, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Human, Primate - Macaca mulatta (Rhesus Macaque) |
Shih CC, Hu MC, Hu J A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood, 2000-03-15;95(6):1957-66. 2000-03-15 [PMID: 10706861] (Bioassay, Human) |
Bioassay |
Human |
Barcena A, Park SW, Banapour B, Muench MO, Mechetner E Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood, 1996-09-15;88(6):2013-25. 1996-09-15 [PMID: 8822920] (Bioassay, Human) |
Bioassay |
Human |
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