Rat ICAM-1/CD54 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

We have publications tested in 1 confirmed species: Rat.

Showing Publications 1 - 10 of 24. Show All 24 Publications. Collapse Publications.

Publications using RIC100	Applications	Species
SF Hashmi, HA Rathore, MA Sattar, EJ Johns, CY Gan, TY Chia, A Ahmad Hydrogen Sulphide Treatment Prevents Renal Ischemia-Reperfusion Injury by Inhibiting the Expression of ICAM-1 and NF-kB Concentration in Normotensive and Hypertensive Rats Biomolecules, 2021-10-19;11(10):. 2021-10-19 [PMID: 34680182] (Rat)		Rat
M Li, Z Zheng Protective effect of parecoxib sodium against ischemia reperfusion?induced intestinal injury Molecular Medicine Reports, 2021-09-09;24(5):. 2021-09-09 [PMID: 34498709] (Rat)		Rat
LL Huo, ZR Sun MiR-128-3p alleviates TNBS-induced colitis through inactivating TRAF6/NF-&kappaB signaling pathway in rats The Kaohsiung journal of medical sciences, 2021-05-27;0(0):. 2021-05-27 [PMID: 34042286] (Rat)		Rat
Y Kong, Y Gao, D Lan, Y Zhang, R Zhan, M Liu, Z Zhu, G Zeng, Q Huang Trans-repression of NF?B pathway mediated by PPAR? improves vascular endothelium insulin resistance J. Cell. Mol. Med., 2018-11-05;0(0):. 2018-11-05 [PMID: 30398029] (Rat)		Rat
Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation Proc. Natl. Acad. Sci. U.S.A, 2016-12-19;0(0):. 2016-12-19 [PMID: 27994152] (Rat)		Rat
Yeh P, Huang H, Yang C, Yang W, Yang C Astaxanthin Inhibits Expression of Retinal Oxidative Stress and Inflammatory Mediators in Streptozotocin-Induced Diabetic Rats. PLoS ONE, 2016-01-14;11(1):e0146438. 2016-01-14 [PMID: 26765843] (Rat)		Rat
Wan , Rong, Jin , Lai, Zhu , Chao, Liu , Yunxin, Li , Li, Guo , Rui, Li , Shengnan Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate. Endocrinology, 2013-09-24;154(12):4663-74. 2013-09-24 [PMID: 24064363] (Rat)		Rat
Lind T, Lind PM, Jacobson A, Hu L, Sundqvist A, Risteli J, Yebra-Rodriguez A, Rodriguez-Navarro A, Andersson G, Melhus H High dietary intake of retinol leads to bone marrow hypoxia and diaphyseal endosteal mineralization in rats. Bone, 2010-10-28;48(3):496-506. 2010-10-28 [PMID: 21035577] (Rat)		Rat
Uray KS, Wright Z, Kislitsyna K, Xue H, Cox CS Nuclear factor-kappaB activation by edema inhibits intestinal contractile activity. Crit. Care Med., 2010-03-01;38(3):861-70. 2010-03-01 [PMID: 20168148] (Rat)		Rat
Kutsuna S, Tsuruta R, Fujita M, Todani M, Yagi T, Ogino Y, Igarashi M, Takahashi K, Izumi T, Kasaoka S, Yuasa M, Maekawa T Cholinergic agonist physostigmine suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in rats with forebrain ischemia/reperfusion. Brain Res., 2009-12-05;1313(0):242-9. 2009-12-05 [PMID: 19968973] (Rat)		Rat
Shevalye H, Stavniichuk R, Xu W, Zhang J, Lupachyk S, Maksimchyk Y, Drel VR, Floyd EZ, Slusher B, Obrosova IG Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model. Biochem. Pharmacol., 2009-11-27;79(7):1007-14. 2009-11-27 [PMID: 19945439] (Rat)		Rat
Tsuruta R, Fujita M, Ono T, Koda Y, Koga Y, Yamamoto T, Nanba M, Shitara M, Kasaoka S, Maruyama I, Yuasa M, Maekawa T Hyperglycemia enhances excessive superoxide anion radical generation, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats. Brain Res., 2009-11-03;1309(0):155-63. 2009-11-03 [PMID: 19891961] (Rat)		Rat
Aki HS, Fujita M, Yamashita S, Fujimoto K, Kumagai K, Tsuruta R, Kasaoka S, Aoki T, Nanba M, Murata H, Yuasa M, Maruyama I, Maekawa T Elevation of jugular venous superoxide anion radical is associated with early inflammation, oxidative stress, and endothelial injury in forebrain ischemia-reperfusion rats. Brain Res., 2009-07-25;1292(0):180-90. 2009-07-25 [PMID: 19635469] (Rat)		Rat
Arita R, Hata Y, Nakao S, Kita T, Miura M, Kawahara S, Zandi S, Almulki L, Tayyari F, Shimokawa H, Hafezi-Moghadam A, Ishibashi T Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage. Diabetes, 2008-10-07;58(1):215-26. 2008-10-07 [PMID: 18840783] (Rat)		Rat
Noda K, She H, Nakazawa T, Hisatomi T, Nakao S, Almulki L, Zandi S, Miyahara S, Ito Y, Thomas KL, Garland RC, Miller JW, Gragoudas ES, Mashima Y, Hafezi-Moghadam A Vascular adhesion protein-1 blockade suppresses choroidal neovascularization. FASEB J., 2008-04-24;22(8):2928-35. 2008-04-24 [PMID: 18436961] (Rat)		Rat
Tarry-Adkins JL, Martin-Gronert MS, Chen JH, Cripps RL, Ozanne SE Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats. FASEB J., 2008-01-29;22(6):2037-44. 2008-01-29 [PMID: 18230683] (Rat)		Rat
LaMarca BD, Chandler DL, Grubbs L, Bain J, McLemore GR, Granger JP, Ryan MJ Role of sex steroids in modulating tumor necrosis factor alpha-induced changes in vascular function and blood pressure. Am. J. Hypertens., 2007-11-01;20(11):1216-21. 2007-11-01 [PMID: 17954370] (Rat)		Rat
Kim YH, Choi MY, Kim YS, Park CH, Lee JH, Chung IY, Yoo JM, Choi WS, Cho GJ, Kang SS Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage. Life Sci., 2007-08-31;81(14):1167-73. 2007-08-31 [PMID: 17881007] (Rat)		Rat
Saha JK, Xia J, Sandusky GE, Chen YF, Gerlitz B, Grinnell B, Jakubowski JA Study of plasma protein C and inflammatory pathways: biomarkers for dimethylnitrosamine-induced liver fibrosis in rats. Eur. J. Pharmacol., 2007-08-02;575(1):158-67. 2007-08-02 [PMID: 17719030] (Rat)		Rat
Yu HP, Hsieh YC, Suzuki T, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. J. Leukoc. Biol., 2007-06-22;82(3):774-80. 2007-06-22 [PMID: 17586659] (Rat)		Rat
Sun Z, Sun B, Wang X, Wang W, Zhu L Anti-inflammatory effects of inhaled nitric oxide are optimized at lower oxygen concentration in experimental Klebsiella pneumoniae pneumonia. Inflamm. Res., 2006-10-01;55(10):430-40. 2006-10-01 [PMID: 17109070] (Rat)		Rat
Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Suzuki F, Oike Y, Ishida S Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin. Invest. Ophthalmol. Vis. Sci., 2006-06-01;47(6):2686-92. 2006-06-01 [PMID: 16723487] (Rat)		Rat
Yu HP, Yang S, Hsieh YC, Choudhry MA, Bland KI, Chaudry IH Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1. Am. J. Physiol. Lung Cell Mol. Physiol., 2006-03-23;291(3):L400-6. 2006-03-23 [PMID: 16556724] (Rat)		Rat
Duan H, Zhang Y, Xu J, Qiao J, Suo Z, Hu G, Mu X Effect of anemonin on NO, ET-1 and ICAM-1 production in rat intestinal microvascular endothelial cells. J Ethnopharmacol, 2005-10-27;104(3):362-6. 2005-10-27 [PMID: 16257161] (Rat)		Rat
Show All 24 Publications. Collapse Publications.

Array RIC100

• ICAM-1/CD54 Antibodies
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• ICAM-1/CD54 ELISA Kits
• ICAM-1/CD54 Lysate
• ICAM-1/CD54 Proteins
• ICAM-1/CD54 ELISAs
• ICAM-1/CD54 Proteins and Enzymes