ICAM-1/CD54 Products

Description

ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

Bioinformatics

Entrez	15894 Mouse 25464 Rat 281839 Bovine 3383 Human
Uniprot	AAH15969 Human CAA30051 Human NM_000201 Human NM_000201.2 Human P05362 Human P13597 Mouse Q00238 Rat
Product By Gene ID	3383
Alternate Names	BB2 CD54 antigen CD54 cell surface glycoprotein P3.58 human rhinovirus receptor ICAM-1 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor intercellular adhesion molecule 1 Major group rhinovirus receptor P3.58

Research Areas for ICAM-1/CD54

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cancer
Cell Biology
Immunology
Mesenchymal Stem Cell Markers
Phospho-Specific
Stem Cell Markers