Human ICAM-1/CD54 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

We have publications tested in 2 confirmed species: Human, Transgenic Mouse.

Showing Publications 1 - 10 of 48. Show All 48 Publications. Collapse Publications.

Publications using DY720	Applications	Species
Hayderi, A;Zegeye, MM;Meydan, S;Sirsjö, A;Kumawat, AK;Ljungberg, LU; TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype International journal of molecular sciences 2024-08-09 [PMID: 39201392] (Human)		Human
Ekelund, C;Dereke, J;Nilsson, C;Landin-Olsson, M; Are soluble E-selectin, ICAM-1, and VCAM-1 potential predictors for the development of diabetic retinopathy in young adults, 15-34 years of age? A Swedish prospective cohort study PloS one 2024-06-06 [PMID: 38843125] (Human)		Human
Rodríguez-Hernández, MÁ;Baena-Bustos, M;Carneros, D;Zurita-Palomo, C;Muñoz-Pinillos, P;Millán, J;Padillo, FJ;Smerdou, C;von Kobbe, C;Rose-John, S;Bustos, M; Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy EBioMedicine 2024-04-26 [PMID: 38677182] (Transgenic Mouse)		Transgenic Mouse
Alehagen, U;Alexander, J;Aaseth, JO;Larsson, A;Svensson, E;Opstad, TB; Effects of an Intervention with Selenium and Coenzyme Q10 on Five Selected Age-Related Biomarkers in Elderly Swedes Low in Selenium: Results That Point to an Anti-Ageing Effect-A Sub-Analysis of a Previous Prospective Double-Blind Placebo-Controlled Randomised Clinical Trial Cells 2023-07-04 [PMID: 37443807] (Human)		Human
Kirsten, N;Ohmes, J;Mikkelsen, MD;Nguyen, TT;Blümel, M;Wang, F;Tasdemir, D;Seekamp, A;Meyer, AS;Fuchs, S; Impact of Enzymatically Extracted High Molecular Weight Fucoidan on Lipopolysaccharide-Induced Endothelial Activation and Leukocyte Adhesion Marine drugs 2023-05-31 [PMID: 37367664] (Human)		Human
VC Capetini, BJ Quintanilh, DC de Oliveir, AH Nishioka, LA de Matos, LRP Ferreira, FM Ferreira, GR Sampaio, NMA Hassimotto, FM Lajolo, RA Fock, MM Rogero Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women: impact on MAPK and NFkappaB signaling pathways The Journal of nutritional biochemistry, 2022-11-26;0(0):109240. 2022-11-26 [PMID: 36442716] (Human)		Human
D Azzopardi, LE Haswell, J Frosina, M McEwan, N Gale, J Thissen, F Meichanetz, G Hardie Biomarkers of Exposure and Potential Harm in Exclusive Users of Nicotine Pouches and Current, Former, and Never Smokers: Protocol for a Cross-sectional Clinical Study JMIR research protocols, 2022-10-06;11(10):e39785. 2022-10-06 [PMID: 36201395] (Human)		Human
ML Sarangam, R Namazzi, D Datta, C Bond, CPB Vanderpool, RO Opoka, CC John, AL Conroy Intestinal Injury Biomarkers Predict Mortality in Pediatric Severe Malaria MBio, 2022-09-07;0(0):e0132522. 2022-09-07 [PMID: 36069443] (Human)		Human
S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)		Human
J Ohmes, MD Mikkelsen, TT Nguyen, VHN Tran, S Meier, MS Nielsen, M Ding, A Seekamp, AS Meyer, S Fuchs Depolymerization of fucoidan with endo-fucoidanase changes bioactivity in processes relevant for bone regeneration Carbohydrate polymers, 2022-02-24;286(0):119286. 2022-02-24 [PMID: 35337530] (Human)		Human
D Sikorska, D Kami?ska, R Catar, M Banasik, H Heidecke, K Schulze-Fo, K Korybalska, R Rutkowski, J ?uczak, J Jab?ecki, A Oko, P Daroszewsk, M Kusztal, W Samborski Non-HLA Antibodies in Hand Transplant Recipients Are Connected to Multiple Acute Rejection Episodes and Endothelial Activation Journal of Clinical Medicine, 2022-02-04;11(3):. 2022-02-04 [PMID: 35160284] (Human)		Human
J Villar, R Herrán-Mon, E González-H, M Prieto-Gon, A Ambrós, A Rodríguez-, A Muriel-Bom, R Solano, C Cuenca-Rub, A Vidal, C Flores, JM González-M, MI García-Lao, Genetics o Clinical and biological markers for predicting ARDS and outcome in septic patients Scientific Reports, 2021-11-22;11(1):22702. 2021-11-22 [PMID: 34811434] (Human)		Human
HW Lee, V Nizet, JN An, HS Lee, YR Song, SG Kim, JK Kim Uremic serum damages endothelium by provoking excessive neutrophil extracellular trap formation Scientific Reports, 2021-11-02;11(1):21439. 2021-11-02 [PMID: 34728714] (Human)		Human
E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes Biology, 2021-08-04;10(8):. 2021-08-04 [PMID: 34439980] (Human)		Human
J Budzianows, J Hiczkiewic, K ?ojewska, E Kawka, R Rutkowski, K Korybalska Predictors of Early-Recurrence Atrial Fibrillation after Catheter Ablation in Women and Men with Abnormal Body Weight Journal of Clinical Medicine, 2021-06-18;10(12):. 2021-06-18 [PMID: 34207297] (Human)		Human
RJ Playford, N Choudhry, P Kelly, T Marchbank Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea Nutrients, 2021-03-22;13(3):. 2021-03-22 [PMID: 33809940] (Human)		Human
AE Wyman, TTT Nguyen, P Karki, ME Tulapurkar, CO Zhang, J Kim, TG Feng, AJ Dabo, NW Todd, IG Luzina, P Geraghty, RF Foronjy, JD Hasday, AA Birukova, SP Atamas, KG Birukov SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells Sci Rep, 2020-07-27;10(1):12497. 2020-07-27 [PMID: 32719338] (Human)		Human
EB Volokhina, WJC Feitz, LM Elders, TJAM van der Ve, NCAJ van de Kar, LPWJ van den He Shiga Toxin Selectively Upregulates Expression of Syndecan-4 and Adhesion Molecule ICAM-1 in Human Glomerular Microvascular Endothelium Toxins (Basel), 2020-07-03;12(7):. 2020-07-03 [PMID: 32635212] (Human)		Human
CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, C Solórzano, M Noursadegh, JS Brown, DM Ferreira, RS Heyderman Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface Nat Commun, 2019-07-16;10(1):3060. 2019-07-16 [PMID: 31311921] (Human)		Human
M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer Cancers (Basel), 2019-05-13;11(5):. 2019-05-13 [PMID: 31086083] (Human)		Human
CR McDonald, AM Weckman, AL Conroy, P Olwoch, P Natureeba, MR Kamya, DV Havlir, G Dorsey, KC Kain Systemic inflammation is associated with malaria and preterm birth in women living with HIV on antiretrovirals and co-trimoxazole Sci Rep, 2019-05-01;9(1):6758. 2019-05-01 [PMID: 31043691] (Human)		Human
I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints Blood inflammatory and endothelial markers in women with von Willebrand disease PLoS ONE, 2019-01-10;14(1):e0210544. 2019-01-10 [PMID: 30629692] (Human)		Human
MC Chang, SI Lin, YH Pan, LD Lin, YL Wang, SY Yeung, HH Chang, JH Jeng IL-1β-induced ICAM-1 and IL-8 expression/secretion of dental pulp cells is differentially regulated by IRAK and p38 J. Formos. Med. Assoc., 2018-12-14;118(8):1247-1254. 2018-12-14 [PMID: 30558829] (Human)		Human
H Leeman, E Kaminska, D Green, M Bodman-Smi, A Gravett, K Bodman-Smi, J Copier, G Coulton, A Fusi, AG Dalgleish Serum Apolipoprotein E and Other Inflammatory Markers Can Identify Non-Responding Patients to a Dendritic Cell Vaccine Transl Oncol, 2018-12-08;12(3):397-403. 2018-12-08 [PMID: 30530187] (Human)		Human
A Bokslag, C Franssen, LJ Alma, I Kovacevic, FV Kesteren, PW Teunissen, O Kamp, W Ganzevoort, PL Hordijk, CJM Groot, WJ Paulus Early-onset preeclampsia predisposes to preclinical diastolic left ventricular dysfunction in the fifth decade of life: An observational study PLoS ONE, 2018-06-12;13(6):e0198908. 2018-06-12 [PMID: 29894501] (Human)		Human
S Liong, R Lim, C Nguyen-Ngo, G Barker, HC Parkington, M Lappas The immunoproteasome inhibitor ONX-0914 regulates inflammation and expression of contraction associated proteins in myometrium Eur. J. Immunol., 2018-06-28;0(0):. 2018-06-28 [PMID: 29883518] (Human)		Human
A Rundblad, KB Holven, I Bruheim, MC Myhrstad, SM Ulven Effects of fish and krill oil on gene expression in peripheral blood mononuclear cells and circulating markers of inflammation: a randomised controlled trial J Nutr Sci, 2018-03-21;7(0):e10. 2018-03-21 [PMID: 29599972] (Human)		Human
JK Wright, K Hayford, V Tran, GM Al Kibria, A Baqui, A Manajjir, A Mahmud, N Begum, M Siddiquee, KC Kain, A Farzin Biomarkers of endothelial dysfunction predict sepsis mortality in young infants: a matched�case-control study BMC Pediatr, 2018-03-23;18(1):118. 2018-03-23 [PMID: 29571293] (Human)		Human
M Oleszowsky, MF Seidel Serum Soluble Vascular Cell Adhesion Molecule-1 Overexpression Is a Disease Marker in Patients with First-Time Diagnosed Antinuclear Antibodies: A Prospective, Observational Pilot Study Biomed Res Int, 2018-02-01;2018(0):8286067. 2018-02-01 [PMID: 29487871] (Human)		Human
A Paunel-Gör, M Wacker, M El Aita, S Hassan, G Schlachten, A Deppe, YH Choi, E Kuhn, TO Mehler, T Wahlers cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner Sci Rep, 2017-12-12;7(1):17421. 2017-12-12 [PMID: 29234042] (Human)		Human
ME Soto, JL Salas, J Vargas-Bar, R Marquez, A Rodriguez-, R Bojalil-Pa, I Pérez-Torr, V Guarner-La Pre- and post-surgical evaluation of the inflammatory response in patients with aortic stenosis treated with different types of prosthesis BMC Cardiovasc Disord, 2017-04-14;17(1):100. 2017-04-14 [PMID: 28410571] (Human)		Human
M Du, A Martin, F Hays, J Johnson, RA Farjo, KM Farjo Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4 Mol. Vis., 2017-03-31;23(0):185-197. 2017-03-31 [PMID: 28400700] (Human)		Human
E Fernlund, T Gyllenhamm, R Jablonowsk, M Carlsson, A Larsson, J Ärnlöv, P Liuba Serum Biomarkers of Myocardial Remodeling and Coronary Dysfunction in Early Stages of Hypertrophic Cardiomyopathy in the Young Pediatr Cardiol, 2017-03-30;0(0):. 2017-03-30 [PMID: 28361263] (Human)		Human
V Selvarani, S Roland, S Andy, H James Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells Virus Res, 2017-03-07;0(0):. 2017-03-07 [PMID: 28279802] (Human)		Human
Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions Oxid Med Cell Longev, 2016-11-23;2016(0):2069290. 2016-11-23 [PMID: 27994710] (Human)		Human
ADAM17 substrate release in proximal tubule drives kidney fibrosis JCI Insight, 2016-08-18;1(13):. 2016-08-18 [PMID: 27642633] (Human)		Human
Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch PLoS ONE, 2016-04-29;11(4):e0153387. 2016-04-29 [PMID: 27128976] (Human)		Human
McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women. PLoS ONE, 2015-08-06;10(8):e0134619. 2015-08-06 [PMID: 26247200] (Human)		Human
Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production. Cell Death Differ, 2015-01-23;22(8):1313-27. 2015-01-23 [PMID: 25613374] (Human)		Human
Greulich T, Nell C, Koepke J, Fechtel J, Franke M, Schmeck B, Haid D, Apelt S, Filipovic S, Kenn K, Janciauskiene S, Vogelmeier C, Koczulla A Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial. BMC Pulm Med, 2014-04-11;14(0):60. 2014-04-11 [PMID: 24725369] (Human)		Human
Conroy A, Gelvez M, Hawkes M, Rajwans N, Liles W, Villar-Centeno L, Kain K Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study. BMC Infect Dis, 2014-01-20;14(0):35. 2014-01-20 [PMID: 24444080] (Human)		Human
Vasquez A, Segura C, Blair S Induction of pro-inflammatory response of the placental trophoblast by Plasmodium falciparum infected erythrocytes and TNF. Malar J, 2013-11-15;12(0):421. 2013-11-15 [PMID: 24237643] (Human)		Human
Fan , Yuqi, Wang , Lianshen, Li , Yuanmin, Yin , Zhaofang, Xu , Zuojun, Wang , Changqia Quantification of endothelial microparticles on modified cytometric bead assay and prognosis in chest pain patients. Circ J, 2013-11-08;78(1):206-14. 2013-11-08 [PMID: 24200872] (Human)		Human
Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, Liles WC, Cserti-Gazdewich CM, Kain KC Combinations of Host Biomarkers Predict Mortality among Ugandan Children with Severe Malaria: A Retrospective Case-Control Study. PLoS ONE, 2011-02-25;6(2):e17440. 2011-02-25 [PMID: 21364762] (Human)		Human
Conroy AL, Phiri H, Hawkes M, Glover S, Mallewa M, Seydel KB, Taylor TE, Molyneux ME, Kain KC Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study. PLoS ONE, 2010-12-29;5(12):e15291. 2010-12-29 [PMID: 21209923] (Human)		Human
Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS ONE, 2009-12-15;4(12):e8300. 2009-12-15 [PMID: 20016852] (Human)		Human
Suri SS, Rakotondradany F, Myles AJ, Fenniri H, Singh B The role of RGD-tagged helical rosette nanotubes in the induction of inflammation and apoptosis in human lung adenocarcinoma cells through the P38 MAPK pathway. Biomaterials, 2009-02-27;30(17):3084-90. 2009-02-27 [PMID: 19250666] (Human)		Human
Hsu HY, Wittemann S, Schneider EM, Weiss M, Joos TO Suspension microarrays for the identification of the response patterns in hyperinflammatory diseases. Med Eng Phys, 2008-03-03;30(8):976-83. 2008-03-03 [PMID: 18313970] (Human)		Human
Show All 48 Publications. Collapse Publications.

Array DY720

• ICAM-1/CD54 Antibodies
• ICAM-1/CD54 Antibody Pairs
• ICAM-1/CD54 ELISA Kits
• ICAM-1/CD54 Lysate
• ICAM-1/CD54 Proteins
• ICAM-1/CD54 ELISAs
• ICAM-1/CD54 Proteins and Enzymes