PTP mu/PTPRM Antibody (436502)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Protein Tyrosine Phosphatase, receptor type M (PTPRM), also called PTPμ, PTPRμ, and RPTPμ, is expressed at highest levels in pulmonary vascular epithelia, where interactions with cadhedrins are believed to be important in regulating barrier permeability. The MAM and Fibronectin III (FNIII) domains on the extracellular side of PTPRM bind between cells, affecting adhesion and contact inhibition. Culturing cells to high density concentrates PTPRM at sites of tight contact and induces proteolytic cleavage of the 100 kDa extracellular domain.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 2 of 2.

Publications using MAB4446	Applications	Species
SH Yoon, BK Kim, MJ Kang, JY Im, M Won Miconazole inhibits signal transducer and activator of transcription 3 signaling by preventing its interaction with DNA damage-induced apoptosis suppressor Cancer Sci., 2020-05-31;0(0):. 2020-05-31 [PMID: 32476221] (Western Blot, Human)	Western Blot	Human
JY Im, BK Kim, KW Lee, SY Chun, MJ Kang, M Won DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells Oncogenesis, 2020-01-02;9(1):1. 1/2/2020 [PMID: 31900385]

Array MAB4446

• PTP mu/PTPRM Antibodies
• PTP mu/PTPRM Protein