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PTH1R/PTHR1 Antibody - BSA Free

Images

 
Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody [NLS761] - Human Bone, Giant Cell Tumor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody [NLS761] - Analysis of anti-PTH1R antibody with human kidney, renal tubules at 2 ug/ml.

Product Details

Summary
Reactivity Hu, Pm, Bv, Pm-Or, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

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PTH1R/PTHR1 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human PTH1R/PTHR1.
Epitope
N-Terminus extracellular domain
Localization
Membrane; multi pass membrane protein.
Specificity
Human PTH1R/PTHR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except UHRF1BP1 (40%).
Predicted Species
Primate (100%), Bovine (95%), Orangutan (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTH1R
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2-4 ug/ml
Application Notes
.
Control
PTH1R/PTHR1 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (100%), Gorilla (95%), Gibbon (95%), Equine (85%), Rabbit (80%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PTH1R/PTHR1 Antibody - BSA Free

  • MGC138426
  • parathyroid hormone 1 receptorMGC138452
  • parathyroid hormone/parathyroid hormone-related peptide receptor
  • parathyroid hormone/parathyroid hormone-related protein receptor
  • PFE
  • PTH/PTHr receptor
  • PTH/PTHrP type I receptor
  • PTH1 receptor
  • PTH1R
  • PTHR
  • PTHR1
  • PTHRPTHR1parathyroid hormone receptor 1
  • seven transmembrane helix receptor

Background

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PTH1R