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PTH1R/PTHR1 Antibody [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

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PTH1R/PTHR1 Antibody [HRP] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human PTH1R/PTHR1 (Uniprot#: Q03431; Met 1-Gly 188)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTH1R
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Antigen and protein A Affinity-purified

Alternate Names for PTH1R/PTHR1 Antibody [HRP]

  • MGC138426
  • parathyroid hormone 1 receptorMGC138452
  • parathyroid hormone/parathyroid hormone-related peptide receptor
  • parathyroid hormone/parathyroid hormone-related protein receptor
  • PFE
  • PTH/PTHr receptor
  • PTH/PTHrP type I receptor
  • PTH1 receptor
  • PTH1R
  • PTHR
  • PTHR1
  • PTHRPTHR1parathyroid hormone receptor 1
  • seven transmembrane helix receptor

Background

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PTH1R