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PSTPIP1 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP1-85764] - Staining in human bone marrow and cerebral cortex tissues using anti-PSTPIP1 antibody. Corresponding PSTPIP1 RNA-seq data are ...read more
Western Blot: PSTPIP1 Antibody [NBP1-85764] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). ...read more
Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP1-85764] - Staining of human bone marrow shows high expression.
Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP1-85764] - Staining of human cerebral cortex shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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PSTPIP1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PSTPIP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PSTPIP1 Protein (NBP1-85764PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (80%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PSTPIP1 Antibody

  • CD2BP1CD2-binding protein 1
  • CD2BP1L
  • CD2BP1S
  • H-PIPPEST phosphatase-interacting protein 1
  • PAPASCD2 antigen-binding protein 1
  • proline-serine-threonine phosphatase interacting protein 1
  • proline-serine-threonine phosphatase-interacting protein 1
  • PSTPIPCD2 cytoplasmic tail-binding protein

Background

The protein encoded by the PSTPIP1 gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PSTPIP1