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PQBP1 Antibody (8D8H6)

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Western Blot: PQBP1 Antibody (8D8H6) [NBP3-16075] - Western blot analysis of extracts of various cell lines, using PQBP1 antibody (NBP3-16075) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB
Clone
8D8H6
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PQBP1 Antibody (8D8H6) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant protein of human PQBP1 Full length (O60828) . MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDKSDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREEGKERRHHRREELAPYPKSKKAVSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PQBP1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for PQBP1 Antibody (8D8H6)

  • 38 kDa nuclear protein containing a WW domain
  • MRX55
  • MRXS3
  • MRXS8
  • Npw38
  • NPW38mental retardation, X-linked 55
  • nuclear protein containing WW domain 38 kD
  • polyglutamine binding protein 1
  • Polyglutamine tract-binding protein 1
  • polyglutamine-binding protein 1
  • PQBP-1
  • RENS1
  • SHS
  • Sutherland-Haan X-linked mental retardation syndrome

Background

PQBP1, also known as Polyglutamine-binding protein 1, is a nuclear polyglutamine-binding protein that may play a role in apoptosis and DNA replication. Ten isoforms of PQBP1 have been identified which are produced by alternative splicing. The canonical sequence, referred to as PQBP-1, is 265 amino acids long and approximately 30kdA. PQBP1 may be implicated in an x-linked mental retardation syndrome called Renpenning syndrome 1 (RENS1), as well as neurodegenerative diseases, coloboma, spastic diplegia, ataxia and neuronitis. PQBP1 has also been shown to interact with C14orf1, MED31, WBP11, CLTB, and SF3A2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PQBP1