PLA2G2A Antibody

The protein encoded by the Phospholipase A2 IIA gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP2-42399	Applications	Species
Villanueva EB, Little JP, Lambeau G, Klegeris A. Secreted phospholipase A(2) group IIA is a neurotoxin released by stimulated human glial cells. Mol Cell Neurosci 2012-04-01 [PMID: 22406427]

Array NBP2-42399

• PLA2G2A Antibodies
• PLA2G2A Kit
• PLA2G2A Lysate
• PLA2G2A Proteins and Enzymes