PLA2G2A Products

Description

The protein encoded by the Phospholipase A2 IIA gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Bioinformatics

Uniprot	AAH05919 Human AAH05919.1 Human NM_000300 Human P14555 Human
Product By Gene ID	5320
Alternate Names	EC 3.1.1.4 GIIC sPLA2 Group IIA phospholipase A2 MOM1 Non-pancreatic secretory phospholipase A2 NPS-PLA2 Phosphatidylcholine 2-acylhydrolase 2A phospholipase A2, group IIA (platelets, synovial fluid) phospholipase A2, membrane associated PLA2BPLA2 PLA2LPLA2S PLAS1 RASF-A sPLA2

Research Areas for PLA2G2A

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism