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PIP Antibody (PIP/9076R) - Azide and BSA Free

Images

 
Formalin-fixed, paraffin-embedded human breast carcinoma stained with PIP antibody (PIP/9076R) - Azide and BSA Free. HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PIP/9076R
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

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PIP Antibody (PIP/9076R) - Azide and BSA Free Summary

Description
Antibody without azide - store at -20 to -80C.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment (around aa 1-146) of human PIP protein (exact sequence is proprietary)
Localization
Cytoplasm (Golgi bodies). Secreted.
Marker
Breast Marker
Specificity
It recognizes a protein of 15kDa, identified as Gross cystic disease fluid protein 15 (GCDFP-15). This antibody is useful in the identification of metastatic breast carcinoma, or fluid analysis.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
PIP
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
10mM PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for PIP Antibody (PIP/9076R) - Azide and BSA Free

  • GCDFP15prolactin-inducible protein
  • GCDFP-15SABP
  • GPIP4gp17
  • Gross cystic disease fluid protein 15
  • prolactin-induced proteinSecretory actin-binding protein

Background

The androgen and prolactin responsive prolactin-inducible protein (PIP), also known as Gross cystic disease fluid protein (GCDFP-15) is expressed in benign and malignant human breast tumors and in such normal exocrine organs as sweat, salivary and lacrimal glands. The hormonally responsive PIP gene is expressed in benign and malignant breast tumor tissues and in such normal exocrine organs as sweat, salivary, and lacrimal glands. The cells within the body that produce PIP/GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found PIP to be a highly specific and sensitive marker for breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PIP