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PI 3-Kinase p110 gamma Antibody (OTI2B1) [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI2B1
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-73397AF350
Alexa Fluor 405
NBP2-73397AF405
Alexa Fluor 488
NBP2-73397AF488
Alexa Fluor 532
NBP2-73397AF532
Alexa Fluor 594
NBP2-73397AF594
Alexa Fluor 647
NBP2-73397AF647
Alexa Fluor 700
NBP2-73397AF700
Alexa Fluor 750
NBP2-73397AF750
Allophycocyanin
NBP2-73397APC
CoraFluor 1
NBP2-73397CL1
DyLight 350
NBP2-73397UV
DyLight 405
NBP2-73397V
DyLight 488
NBP2-73397G
DyLight 550
NBP2-73397R
DyLight 594
NBP2-73397DL594
DyLight 650
NBP2-73397C
DyLight 680
NBP2-73397FR
DyLight 755
NBP2-73397IR
FITC
NBP2-73397F
HRP
NBP2-73397H
Janelia Fluor 525
NBP2-73397JF525
Janelia Fluor 549
NBP2-73397JF549
Janelia Fluor 585
NBP2-73397JF585
Janelia Fluor 635
NBP2-73397JF635
Janelia Fluor 646
NBP2-73397JF646
Janelia Fluor 669
NBP2-73397JF669
PE
NBP2-73397PE
PerCP
NBP2-73397PCP
Unconjugated
NBP2-46411
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46411
Azide and BSA Free
NBP2-73397
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PI 3-Kinase p110 gamma Antibody (OTI2B1) [Biotin] Summary

Immunogen
Full length recombinant protein of human PI 3-Kinase p110 gamma (NP_002640) produced in HEK293T cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PIK3CG
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PI 3-Kinase p110 gamma Antibody (OTI2B1) [Biotin]

  • 1-phosphatidylinositol 3-kinase
  • EC 2.7.1
  • EC 2.7.1.153
  • p110-gamma
  • p120-PI3K
  • phosphatidylinositol 3 kinase gamma, p110 gamma
  • phosphatidylinositol 3-kinase catalytic 110-kD gamma
  • phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
  • Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • phosphoinositide-3-kinase gamma catalytic subunit
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • PI 3Kinase p110 gamma
  • PI 3-Kinase p110 gamma
  • PI3CG
  • PI3K
  • PI3K-gamma
  • PI3Kgamma
  • PI3K-gamma
  • PI3-kinase subunit gamma
  • PIK3
  • PIK3CG
  • PtdIns-3-kinase subunit gamma
  • PtdIns-3-kinase subunit p110-gamma

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PI 3-Kinase p110 gamma Antibody (OTI2B1) [Biotin]
Species: Hu, Mu, Rt
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Bioinformatics

Gene Symbol PIK3CG