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Human Peroxiredoxin 6 ELISA Kit (Colorimetric)

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ELISA: Human Peroxiredoxin 6 ELISA Kit (Colorimetric) [NBP3-18736] - Standard Reference Curve
ELISA: Human Peroxiredoxin 6 ELISA Kit (Colorimetric) [NBP3-18736] - Standard Reference Curve

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, Plasma, Cell Culture, Saliva, Milk, Tissue Extract
Standard Curve Range
0.125 - 8 ng/mL (example only; lot dependent)
Sensitivity
80 pg/mL (example only; lot dependent)

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Human Peroxiredoxin 6 ELISA Kit (Colorimetric) Summary

Standard Curve Range
0.125 - 8 ng/mL (example only; lot dependent)
Sensitivity
80 pg/mL (example only; lot dependent)
Assay Type
Sandwich ELISA
Inter-Assay
CV%< 10.8 (example only; lot dependent)
Intra-Assay
CV%< 6.1 (example only; lot dependent)
Spike Recovery
96% (example only; lot dependent)
Kit Type
ELISA Kit (Colorimetric)
Gene
PRDX6

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage is content dependent.

Alternate Names for Human Peroxiredoxin 6 ELISA Kit (Colorimetric)

  • 1-Cys
  • 24 kDa protein
  • Acidic calcium-independent phospholipase A2
  • aiPLA2
  • aiPLA21-Cys PRX
  • Antioxidant protein 2
  • AOP2
  • AOP2Non-selenium glutathione peroxidase
  • EC 1.11.1.15
  • EC 1.11.1.7
  • EC 3.1.1.-
  • KIAA0106Red blood cells page spot 12
  • Liver 2D page spot 40
  • MGC46173
  • NSGPx
  • NSGPx1-Cys peroxiredoxin
  • p29
  • Peroxiredoxin 6
  • peroxiredoxin-6
  • PRDX6
  • PRX

Background

FUNCTION: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. SUBUNIT: Homotetramer. May interact with HTR2A. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Note=Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin . MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol PRDX6