PRRX1 Antibody

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: IF/IHC, IHC-P, Immunoprecipitation, WB, Western Blot.

Showing Publications 1 - 8 of 8.

Publications using NBP1-06067	Applications	Species
Subha Sankar Paul, Som Mohanlal Patwa, Yee-Joo Tan Development of monoclonal antibodies to target the large surface protein of hepatitis B virus and their use in therapeutic and diagnostic applications. Journal of viral hepatitis 2023-10-23 [PMID: 37525419]
Wang T, Wagner RT, Hlady RA et al. SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-?-independent manner Molecular oncology 2023-07-07 [PMID: 37418588] (WB, Human)	WB	Human
Marchini M, Ashkin MR, Bellini M Et al. A Na(+)/K(+) ATPase Pump Regulates Chondrocyte Differentiation and Bone Length Variation in Mice Front Cell Dev Biol 2021-12-31 [PMID: 34970538] (IF/IHC, Mouse) Details: Citation using the HRP version of this antibody.	IF/IHC	Mouse
Tanabe R, Miyazono K, Todo T et al. PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3A Molecular Oncology 2022-01-01 [PMID: 34214250] (Immunoprecipitation, Western Blot)	Immunoprecipitation, Western Blot
Funada K, Yoshizaki K, Miyazaki K et Al. microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development Sci Rep 2020-03-18 [PMID: 32188878] (IF/IHC, Mouse)	IF/IHC	Mouse
Fan M, Shen J, Liu H et al. Downregulation of PRRX1 via the p53-dependent Signaling Pathway Predicts Poor Prognosis in Hepatocellular Carcinoma Oncol Rep. 2017-08-01 [PMID: 28677793] (WB, Human)	WB	Human
Reichert M, Takano S, Burstin J et al. The Prrx1 Homeodomain Transcription Factor Plays a Central Role in Pancreatic Regeneration and Carcinogenesis Genes Dev. 2013-02-01 [PMID: 23355395] (IHC-P, Mouse)	IHC-P	Mouse
Kim YJ, Ahn JY, Liang P et al. Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology. Cancer Res 2007 Jan 15 [PMID: 17234762]

Array NBP1-06067

• PRRX1 Antibodies
• PRRX1 Lysates
• PRRX1 Proteins