Peroxiredoxin 3 Antibody

This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP2-19777	Applications	Species
Kumar A, Vaish M, Karuppagounder SS et al. HIF1? stabilization in hypoxia is not oxidant-initiated eLife 2021-10-01 [PMID: 34596045]

Array NBP2-19777

• Peroxiredoxin 3 Antibodies
• Peroxiredoxin 3 Lysate
• Peroxiredoxin 3 Proteins