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PDE1A Antibody

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Western Blot: PDE1A Antibody [NBP3-12241] - WB of NBP3-12241. 1:500- antibody Dilution in DiluObuffer.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PDE1A Antibody Summary

Immunogen
Synthetic peptide corresponding to unique amino acid sequence within amino acid region 1-50 on PDE1A protein. Common to all PDE1A variants.
Clonality
Polyclonal
Host
Rabbit
Gene
PDE1A
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:10000
  • Immunocytochemistry/ Immunofluorescence 1:200
  • Immunohistochemistry 1:200
  • Immunoprecipitation 1:200
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for PDE1A Antibody

  • 3'-5' cyclic nucleotide phosphodiesterase
  • 61 kDa Cam-PDE
  • calcium/calmodulin-dependent 3'-5'-cyclic nucleotide phosphodiesterase 1A
  • calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
  • calmodulin-dependent phosphodiesterase
  • Cam-PDE 1A
  • EC 3.1.4
  • EC 3.1.4.17
  • HCAM1
  • hCam-1
  • HSPDE1A
  • MGC26303
  • PDE1A
  • phosphodiesterase 1A, calmodulin-dependent
  • phosphodiesterase-1A

Background

PDE1A, a variant of PDE1, is a Ca2+-calmodulin-stimulated phosphodieterase (PDE) preferentially hydrolyzing cGMP. Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, B, and C). PDE1A and PDE1B have higher affinity for cGMP than for cAMP, whereas PDE1C has high affinity for both cAMP and cGMP. The PDE1A gene family includes various proteins that differ from each other at amino and carboxy termini of the protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PDE1A