PDE1A Antibody Summary
Immunogen |
Synthetic peptide corresponding to unique amino acid sequence within amino acid region 1-50 on PDE1A protein. Common to all PDE1A variants. |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
PDE1A |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:10000
- Immunocytochemistry/ Immunofluorescence 1:200
- Immunohistochemistry 1:200
- Immunoprecipitation 1:200
- Western Blot 1:500-1:1000
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary). |
Preservative |
0.02% Sodium Azide |
Purity |
Affinity purified |
Alternate Names for PDE1A Antibody
Background
PDE1A, a variant of PDE1, is a Ca2+-calmodulin-stimulated phosphodieterase (PDE) preferentially hydrolyzing cGMP. Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, B, and C). PDE1A and PDE1B have higher affinity for cGMP than for cAMP, whereas PDE1C has high affinity for both cAMP and cGMP. The PDE1A gene family includes various proteins that differ from each other at amino and carboxy termini of the protein.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Secondary Antibodies
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