PD-L2/B7-DC/PDCD1LG2 Antibody (168633) [DyLight 550] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse PD-L2/B7-DC Met1-Arg219 Accession # Q9WUL5 |
Specificity |
Detects mouse PD-L2/B7-DC in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human (rh) PD-L2 is observed and no cross-reactivity with rhB7-1, recombinant mouse (rm) B7-1, rmB7-2, rmB7-H1, rmB7-H2, rmB7‑H3, or rmB7-H4 is observed. |
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
PDCD1LG2 |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody (168633) [DyLight 550]
Background
B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for PD-L2/B7-DC/PDCD1LG2 Antibody (FAB1022L) (0)
Secondary Antibodies
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