PD-L2/B7-DC/PDCD1LG2 Antibody (168633) [Allophycocyanin/Cy7] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse PD-L2/B7-DC Met1-Arg219 Accession # Q9WUL5 |
Specificity |
Detects mouse PD-L2/B7-DC in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human (rh) PD-L2 is observed and no cross-reactivity with rhB7-1, recombinant mouse (rm) B7-1, rmB7-2, rmB7-H1, rmB7-H2, rmB7‑H3, or rmB7-H4 is observed. |
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
PDCD1LG2 |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
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Application Notes |
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. Do not freeze. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody (168633) [Allophycocyanin/Cy7]
Background
B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for PD-L2/B7-DC/PDCD1LG2 Antibody (FAB1022APCCY7) (0)
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FAQs for PD-L2/B7-DC/PDCD1LG2 Antibody (FAB1022APCCY7) (0)
Secondary Antibodies
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