Pax7 Antibody (PAX7/497) [Alexa Fluor® 488] Summary
Immunogen |
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759) |
Localization |
Nuclear |
Marker |
Rhabdomyosarcoma Marker |
Isotype |
IgG1 Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
PAX7 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Western Blot
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Publications |
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Notes
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for Pax7 Antibody (PAX7/497) [Alexa Fluor® 488]
Background
PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Pax7 Antibody (NBP2-34706AF488)(1)
Showing Publication 1 -
1 of 1.
Publication using NBP2-34706AF488 |
Applications |
Species |
Dhanushika Ratnayake, Phong D Nguyen, Fernando J Rossello, Verena C Wimmer, Jean L Tan, Laura A Galvis, Ziad Julier, Alasdair J Wood, Thomas Boudier, Abdulsalam I Isiaku, Silke Berger, Viola Oorschot, Carmen Sonntag, Kelly L Rogers, Christophe Marcelle, Graham J Lieschke, Mikaël M Martino, Jeroen Bakkers, Peter D Currie Macrophages provide a transient muscle stem cell niche via NAMPT secretion. Nature 2021-04-05 [PMID: 33568815] |
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