PAUF/ZG16B Antibody (817310) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

PAUF (pancreatic adenocarcinoma upregulated factor), gene name ZG16B (zymogen granule protein 16B), is a 156 amino acid, approximately 20-25 kDa secreted protein that is a member of the jacalin-binding lectin family. PAUF expression is thought to be restricted to primates, but the related ZG16P, which shares approximately 25% amino acid sequence identity, is more widely expressed. Human PAUF is overexpressed in pancreatic adenocarcinoma, binds Toll-like receptors TLR2 and TLR4, and inhibits CXCR4-dependent, TLR2-mediated NF-kB activation. It facilitates tumor growth, adhesiveness, and production of pro-tumorigenic cytokines.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC-P, Western Blot.

Showing Publication 1 - 1 of 1.

Publication using MAB7777	Applications	Species
CH Choi, TH Kang, JS Song, YS Kim, EJ Chung, K Ylaya, S Kim, SS Koh, JY Chung, JH Kim, SM Hewitt Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer Sci Rep, 2018-08-15;8(1):12161. 2018-08-15 [PMID: 30111860] (IHC-P, Western Blot, Human)	IHC-P, Western Blot	Human

Array MAB7777

• PAUF/ZG16B Antibodies
• PAUF/ZG16B ELISA Kits
• PAUF/ZG16B Lysates
• PAUF/ZG16B Proteins