PAUF/ZG16B Antibody (6E5)

Images

 
ELISA: PAUF/ZG16B Antibody (6E5) [NBP3-26244] - The Binding Activity of Human PAUF/ZG16B with PAUF/ZG16B Antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PAUF/ZG16B at 2 ug/mL ...read more
ELISA: PAUF/ZG16B Antibody (6E5) [NBP3-26244] -The Binding Activity of Macaca fascicularis ZG16B with Anti-ZG16B recombinant antibodyActivity: Measured by its binding ability in a functional ELISA. Immobilized Macaca ...read more

Product Details

Summary
Reactivity Hu, Pm-CmSpecies Glossary
Applications ELISA
Clone
6E5
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated

Order Details

PAUF/ZG16B Antibody (6E5) Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
Recombinant Human PAUF/ZG16B protein [UniProt Q96DA0]
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
ZG16B
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol, 0.01M PBS, PH 7.4
Preservative
0.03% Proclin 300
Purity
Affinity purified

Alternate Names for PAUF/ZG16B Antibody (6E5)

  • DKFZp762P2216
  • EC 3.1.2
  • EC 3.4.19.12
  • EECP
  • HRPE773
  • hTrabid
  • JCLN2
  • LOC124220
  • PAUF
  • PRO1567
  • TRABIDubiquitin thioesterase ZRANB1
  • TRAF-binding protein domain
  • ZG16B
  • Zinc finger Ran-binding domain-containing protein 1
  • zinc finger, RAN-binding domain containing 1

Background

PAUF (pancreatic adenocarcinoma upregulated factor), gene name ZG16B (zymogen granule protein 16B), is a 156 amino acid, approximately 20-25 kDa secreted protein that is a member of the jacalin-binding lectin family. PAUF expression is thought to be restricted to primates, but the related ZG16P, which shares approximately 25% amino acid sequence identity, is more widely expressed. Human PAUF is overexpressed in pancreatic adenocarcinoma, binds Toll-like receptors TLR2 and TLR4, and inhibits CXCR4-dependent, TLR2-mediated NF-kB activation. It facilitates tumor growth, adhesiveness, and production of pro-tumorigenic cytokines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ZG16B