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Panendothelial Cell Antigen Antibody (MECA-32) [mFluor Violet 500 SE]

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Panendothelial Cell Antigen Antibody (MECA-32) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP, CyTOF-ready
Clone
MECA-32
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 500 SE

Order Details

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Panendothelial Cell Antigen Antibody (MECA-32) [mFluor Violet 500 SE] Summary

Immunogen
Mouse lymph node stromal cells.
Specificity
Pan endothelial cells except for CNS & muscle capillaries.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
Plvap
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Panendothelial Cell Antigen Antibody (MECA-32) [mFluor Violet 500 SE]

  • FELS
  • Fenestrated endothelial-linked structure protein
  • gp68
  • MECA32
  • MECA-32
  • Panendothelial Cell Antigen
  • plasmalemma vesicle associated protein
  • Plasmalemma Vesicle Protein 1
  • PV-1 protein

Background

MECA-32 is a 50-55 kD homodimer glycoprotein primarily expressed on most endothelial cells in the embryonic and the adult mouse tissues, except in the brain and in skeletal and cardiac muscle, where it has more restricted distribution. In skeletal and cardiac muscle, the MECA-32 antigen is confined in small arterioles and venules. But in some conditions, such as inflammation or cardiac transplantation, MECA-32 expression can be induced on some negative-cardiac endothelial cells. In the brain, its expression occurs only in the circumventricular organs and the neurohemal tissues. During embryonic development, MECA-32 antigen is expressed on the brain vasculature up to day 16 of gestation, and disappears at day 17 and after.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Panendothelial Cell Antigen Antibody (NB100-77668MFV500) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol Plvap