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PAK6 Antibody [Janelia Fluor® 635]

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Summary
Product Discontinued
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    • Catalog Number
      NBP2-99551JF635
    • Availability
      Product Discontinued

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PAK6 Antibody [Janelia Fluor® 635] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human PAK6
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAK6
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PAK6 Antibody [Janelia Fluor® 635]

  • EC 2.7.11
  • p21 protein (Cdc42/Rac)-activated kinase 6
  • p21(CDKN1A)-activated kinase 6
  • p21-activated kinase 6
  • p21-activated protein kinase 6
  • PAK-5
  • PAK5EC 2.7.11.1
  • PAK6
  • PAK-6
  • serine/threonine-protein kinase PAK 6

Background

PAK6, a novel AR-interacting protein, shares a high degree of sequence similarity with other p21-activated kinases (PAK). PAK6 co-translocates into the nucleus with AR in response to androgen. In addition, AR and ER alpha transcriptional activites were inhibited by PAK6 in transient transfections with episomal and integrated reporter genes. PAK, which is highly expressed in testis and prostate tissues, could contribute to the effects of tamoxifen in breast cancer and in other tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PAK6