PAK6 Products

Description

PAK6, a novel AR-interacting protein, shares a high degree of sequence similarity with other p21-activated kinases (PAK). PAK6 co-translocates into the nucleus with AR in response to androgen. In addition, AR and ER alpha transcriptional activites were inhibited by PAK6 in transient transfections with episomal and integrated reporter genes. PAK, which is highly expressed in testis and prostate tissues, could contribute to the effects of tamoxifen in breast cancer and in other tissues.

Bioinformatics

Uniprot	NM_020168 Human NP_001122100 Human NP_001122101 Human NP_064553 Human NP_064553.1 Human Q9NQU5 Human
Product By Gene ID	56924
Alternate Names	EC 2.7.11 p21 protein (Cdc42/Rac)-activated kinase 6 p21(CDKN1A)-activated kinase 6 p21-activated kinase 6 p21-activated protein kinase 6 PAK-5 PAK5EC 2.7.11.1 PAK-6 serine/threonine-protein kinase PAK 6

Research Areas for PAK6

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
DNA Repair
GPCR
Phospho-Specific
Protein Kinase
Signal Transduction