p70 S6 Kinase/S6K Antibody

S6K encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP2-23649	Applications	Species
Acharya S, Dilnawaz F, Sahoo SK. Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy. Biomaterials. 2009-10-01 [PMID: 19631377] (WB) Details: EGFR (IMG-80179) FA: The EGFR antibody was conjugated to 6-coumarin loaded nanoparticles. The EGFR antibody was labeled with a FITC secondary antibody (Cat#(2010)2). Intracellular uptake of the antibody labeled nanoparticles in MCF 7 breast cancer cells was visualized using immunofluorescence, Fig 7. (Note) Diagram of molecular mechanism of drug uptake using the EGFR antibody, Fig 10. 2. Anti-Mouse IgG (H+L) FITC Conjugate (20102): The antibody was used to label the EGFR antibody.	WB

Array NBP2-23649

• p70 S6 Kinase/S6K Antibodies
• p70 S6 Kinase/S6K ELISA Kit
• p70 S6 Kinase/S6K Lysate
• p70 S6 Kinase/S6K Proteins
• p70 S6 Kinase/S6K ELISAs
• p70 S6 Kinase/S6K Proteins and Enzyme