p63/TP73L Antibody (87C553)

This Product is Only Available For Sale Outside of USA. Optimal dilution of this antibody should be experimentally determined.

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NB100-56549	Applications	Species
Terrasson J, Xu B, Li M et al. Activities of Z-ajoene against tumour and viral spreading in vitro. Fundam Clin Pharmacol. 2007-06-01 [PMID: 17521297] (WB) Details: p63 (IMG-348). WB: Jurkat cell line treated with increasing concentrations of Z-ajoene, Fig 2.	WB

Array NB100-56549

• p63/TP73L Antibodies
• p63/TP73L ELISA Kits
• p63/TP73L Proteins