| Reactivity | Hu, MuSpecies Glossary |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugate | Unconjugated |
| Concentration | LYOPH |
| Immunogen | E. coli-derived recombinant human Otoraplin/OTOR Val18-Glu128 Accession # Q9NRC9 |
| Specificity | Detects human and mouse Otoraplin/OTOR in direct ELISAs and Western blots. |
| Source | N/A |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Gene | OTOR |
| Purity Statement | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Concentration | LYOPH |
| Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
Otoraplin (OTOR), also known as fibrocyte-derived protein (Fdp) and Melanoma inhibitory activity-like (MIAL), is a secreted 16 kDa globular protein that is preferentially expressed in the inner ear by periotic mesenchyme and developing and mature fibrocytes. It is highly homologous to MIA/cartilage-derived retinoic acid‑sensitive protein (CD-RAP), which is a cartilage-specific protein that is also expressed in malignant melanoma cells. The 111 amino acid residue (aa) mature human otoraplin contains one SH3 domain (aa 46‑107) and a Tyr at position 50 that is reportedly sulfated. Otoraplin is reported to play a role in the initiation of periotic mesenchyme chondrogenesis. Mature human Otoraplin shares 91% and 89% aa sequence identity with canine and mouse Otoraplin, respectively.
Secondary Antibodies |
Isotype Controls |
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