Nup153 Antibody

Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex specific glycoproteins characterized by cytoplasmically oriented O linked N acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. Nup153 has three distinct domains: a N terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C terminal region containing multiple XFXFG repeats. Nup153 is a possible DNA binding subunit of the nuclear pore complex (NPC). The repeat containing domain may be involved in anchoring components of the pore complex to the pore membrane.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IF	Human	02/21/2019	View Summary Application Immunofluorescence Sample Tested human lung cancer cell line Species Human Lot R28523 Comments Comments HCC44 cells Fixation in 4% PFA 20min RT Permeabilisation 3” in 0,5% Triton Blocking in 1,5% fish gelatin, 0,05% Tween20 Primary antibody diluted in blocking solution at 1:100 and incubated overnight Si Nup153: GGACUUGUUAGAUCUAGUU

Array NBP1-81724

• Nup153 Antibodies
• Nup153 Proteins