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NTS2/NTSR2 Antibody

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Immunohistochemistry-Paraffin: NTS2/NTSR2 Antibody [NBP3-14429] - NTS2/NTSR2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Pm, PmSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

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NTS2/NTSR2 Antibody Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from internal region of human NTS2/NTSR2.
Epitope
Internal
Specificity
Human NTS2/NTSR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (94%), Rat (94%), Primate (100%), Monkey (94%), Bovine (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
NTSR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

Reactivity Notes

Expected reactivity based on percent sequence identity: Canine, Hamster, Porcine (88%)

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NTS2/NTSR2 Antibody

  • neurotensin receptor 2
  • neurotensin receptor type 2
  • neurotensin receptor, type 2
  • NT-R-2
  • NTR2Levocabastine-sensitive neurotensin receptor
  • NTS2
  • NTSR2

Background

Official Gene Symbol: NTSR2 Gen Bank Accession Number: NP_036476 Gene ID: 23620 (Human) Gene Map Locus: 2p25.1 (Human) NTR2 is a member of GPCR family. It contains a short N-terminal sequence, 7 transmembrane domains and a short cytoplasmic tail. It is a low affinity levocabastine-sensitive receptor for Neurotensin. Activation of NT2R by non-peptide agonists suggests that the receptor can couple to phospholipase C, phospholipase A2 and MAPK. Unlike NTR1, NTR2 is insensitive to GTP and has low sensitivity of sodium ions. Northern Blot analysis detected its expression in adult brain regions including the olfactory system, cerebral and crebellar cortices, hippocampus and hypothalamic nuclei. Its expression has also been found in low levels in kidney, uterus, heart and lung.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NTSR2