![Western Blot: Neuregulin-1/NRG1 Antibody [NBP2-19588] - Rat tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody [C1C3] diluted at 1:2000.](http://images.novusbio.com/fullsize/Neuregulin-1-NRG1-Antibody-Western-Blot-NBP2-19588-img0003.jpg "Western Blot: Neuregulin-1/NRG1 Antibody [NBP2-19588] - Rat tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody [C1C3] diluted at 1:2000.")
| Reactivity | Hu, Mu, RtSpecies Glossary |
| Applications | WB, ICC/IF |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugate | Unconjugated |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Neuregulin-1/NRG1. The exact sequence is proprietary. |
| Localization | Pro-neuregulin-1; membrane-bound isoform: Cell membrane; Single-pass type I membrane protein; Neuregulin-1: Secreted; Isoform 8: Nucleus; Isoform 9: Secreted; Isoform 10: Membrane; Single-pass type I membrane protein |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
| Gene | NRG1 |
| Purity | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Theoretical MW | 70 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Buffer | PBS, 1% BSA, 20% Glycerol |
| Preservative | 0.01% Thimerosal |
| Purity | Antigen Affinity-purified |
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| Publications using NBP2-19588 | Applications | Species |
|---|---|---|
| Carús-Cadavieco M, Berenguer López I, Montoro Canelo A et al. Cognitive decline in diabetic mice predisposed to Alzheimer's disease is greater than in wild type Life science alliance 2023-06-01 [PMID: 37059474] (Western Blot, Mouse) | Western Blot | Mouse |
| Elfving B, Muller HK, Oliveras I et al. Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior Prog. Neuropsychopharmacol. Biol. Psychiatry 2019-06-20 [PMID: 31228641] (WB, Rat) | WB | Rat |
| Carus-Cadavieco M, Lopez I, Canelo A et al. Diabetes-associated cognitive decline in mice with genetic predisposition to Alzheimer's disease, not in wild type Research Square 2022-07-21 (WB, Mouse) | WB | Mouse |
Secondary Antibodies |
Isotype Controls |
Research Areas for Neuregulin-1/NRG1 Antibody (NBP2-19588)Find related products by research area.
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![Immunocytochemistry/Immunofluorescence: Neuregulin-1/NRG1 Antibody [NBP2-19588] - Neuregulin-1 antibody detects Neuregulin-1 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Neuregulin-1 stained by Neuregulin-1 antibody diluted at 1:500. Red: Tau, stained by Tau antibody diluted at 1:500. Blue: Fluoroshield with DAPI.](http://images.novusbio.com/fullsize/Neuregulin-1-NRG1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-19588-img0004.jpg "Immunocytochemistry/Immunofluorescence: Neuregulin-1/NRG1 Antibody [NBP2-19588] - Neuregulin-1 antibody detects Neuregulin-1 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Neuregulin-1 stained by Neuregulin-1 antibody diluted at 1:500. Red: Tau, stained by Tau antibody diluted at 1:500. Blue: Fluoroshield with DAPI.")
![Western Blot: NRG1 Antibody [NBP2-19588] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE gel, diluted at 1:2000.](http://images.novusbio.com/fullsize/NRG1-Antibody-Western-Blot-NBP2-19588-img0001.jpg "Western Blot: NRG1 Antibody [NBP2-19588] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE gel, diluted at 1:2000.")
![Western Blot: Neuregulin-1/NRG1 Antibody [NBP2-19588] - Mouse tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody [C1C3] diluted at 1:2000.](http://images.novusbio.com/fullsize/Neuregulin-1-NRG1-Antibody-Western-Blot-NBP2-19588-img0002.jpg "Western Blot: Neuregulin-1/NRG1 Antibody [NBP2-19588] - Mouse tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Neuregulin-1 antibody [C1C3] diluted at 1:2000.")
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