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Myocilin Antibody

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Western Blot: Myocilin Antibody [NBP1-89769] - Analysis in human adipose tissue .
Western Blot: Myocilin Antibody [NBP1-89769] - Analysis in human adipose tissue .
Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769] - Staining of human gastrointestinal shows strong cytoplasmic granular positivity in glandular cells.
Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-89769] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Myocilin Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: NLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRIL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MYOC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Myocilin Protein (NBP1-89769PEP)
Publications
Read Publication using
NBP1-89769 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Myocilin Antibody

  • GLC1A
  • GLC1Amyocilin
  • GPOA
  • JOAG
  • JOAG1
  • MYOC
  • Myocilin
  • myocilin, trabecular meshwork inducible glucocorticoid response
  • TIGR
  • TIGRmutated trabecular meshwork-induced glucocorticoid response protein
  • Trabecular meshwork-induced glucocorticoid response protein

Background

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Myocilin Antibody (NBP1-89769)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol MYOC