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MSS4 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: MSS4 Antibody [NBP1-87832] - Staining of human cell line Hep G2 shows localization to nucleus.
Immunohistochemistry-Paraffin: MSS4 Antibody [NBP1-87832] - Staining of human testis shows strong cytoplasmic positivity in subset of cells in seminiferous ducts.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MSS4 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: YFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSH
Predicted Species
Mouse (93%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PIP5K1B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
MSS4 Protein (NBP1-87832PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MSS4 Antibody

  • EC 2.7.1
  • MSS4Protein STM-7
  • Phosphatidylinositol-4-phosphate 5-kinase type I beta
  • phosphatidylinositol-4-phosphate 5-kinase type-1 beta
  • phosphatidylinositol-4-phosphate 5-kinase, type I, beta
  • PIP5K1-beta
  • PIP5KIbeta
  • PtdIns(4)P-5-kinase 1 beta
  • STM7EC 2.7.1.68
  • Type I phosphatidylinositol-4-phosphate 5-kinase beta

Background

MSS4, also known by its gene name PIP5K1B, has a 543 amino acid long isoform that is 61 kDa and a 549 amino acid isoform that is approximately 62 kDa. MSS4 plays a role in platelet adhesion, actin filament organization and the biosynthesis of PIP2. Current research on MSS4 is being conducted in relation to several diseases and disorders including kidney disease, schizophrenia, neuronitis and Friedreich's ataxia. MSS4 has also been shown to have interactions with CLIC1, BTK, MCRS1 and PIP5KL1 in pathways such as the RAC1 signaling pathway, CD28 signaling, Phosphatidylinositol signaling and the metabolism of lipids and lipoproteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for MSS4 Antibody (NBP1-87832) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PIP5K1B