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MSPR/Ron Antibody

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Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human colon.
Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human colon.
Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human salivary gland shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.
Independent Antibodies: Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human cerebral cortex, colon, lymph node and skin using Anti-MST1R antibody NBP1-88137 (A) shows similar ...read more
Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human lymph node.
Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: MSP R/Ron Antibody [NBP1-88137] - Staining of human skin.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

        

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MSPR/Ron Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSFCPNPPGLEALSPNTSCRHFPLLVSSSF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MST1R
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
MSPR/Ron Recombinant Protein Antigen (NBP1-88137PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MSPR/Ron Antibody

  • CD136 antigen
  • CD136
  • CDw136c-met-related tyrosine kinase
  • EC 2.7.10
  • EC 2.7.10.1
  • macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • MSP R
  • MSP receptor
  • MSPR
  • MST1R
  • p185-Ron
  • Protein-tyrosine kinase 8
  • PTK8 protein tyrosine kinase 8
  • PTK8
  • Ron
  • RONmacrophage-stimulating protein receptor
  • soluble RON variant 1
  • soluble RON variant 2
  • soluble RON variant 3
  • soluble RON variant 4

Background

Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MST1R