MSP/MST1 Antibody (45904) [Unconjugated] - a Chain

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ELISA Development, ELISA Development (Capture).

Showing Publications 1 - 4 of 4.

Publications using MAB352	Applications	Species
Viventi S, Frausin S, Howden SE et al. In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia Stem cells translational medicine 3/18/2021 [PMID: 33734599]
HIV?1 downregulates the expression and phosphorylation of receptor tyrosine kinase by targeting the NF??B pathway Mol Med Rep, 2016-07-08;0(0):. 2016-07-08 [PMID: 27432185] (ELISA Development (Capture), Human)	ELISA Development (Capture)	Human
Kauder , Steven E, Santell , Lydia, Mai , Elaine, Wright , Lilyan Y, Luis , Elizabet, N'Diaye , Elsa N, Lutman , Jeff, Ratti , Navneet, Sa , Susan M, Maun , Henry R, Stefanich , Eric, Gonzalez , Lino C, Graham , Robert R, Diehl , Lauri, Faubion , William, Keir , Mary E, Young , Judy, Chaudhuri , Amitabha, Lazarus , Robert A, Egen , Jackson Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele. PLoS ONE, 2013-12-23;8(12):e83958. 2013-12-23 [PMID: 24409221] (ELISA Development, Human)	ELISA Development	Human
Kerrington R. Molhoek, Amber L. Shada, Mark Smolkin, Sudhir Chowbina, Jason Papin, David L. Brautigan et al. Comprehensive analysis of receptor tyrosine kinase activation in human melanomas reveals autocrine signaling through IGF-1R Melanoma Research 2011-08-01 [PMID: 21654344]

Array MAB352

• MSP/MST1 Antibodies
• MSP/MST1 Protein
• MSP/MST1 Proteins and Enzymes
• MSP/MST1 ELISAs