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MRP3 Antibody (M3II-9)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
M3II-9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.

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MRP3 Antibody (M3II-9) Summary

Description
The concentration of this material is approximately 0.25mg immunoglobulin/ml.
Immunogen
MRP3 (aa 830-949)
Specificity
Reacts with an internal epitope of MRP3. Does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ABCC3
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Western Blot 1:100-1:2000
Application Notes
M3II-9 has potential value for detection of MRP3-mediated drug-resistance in human tumor samples. Immnocytochemistry: use 1:20-1:50 dil. on acetone or formaldehyde fixed cytospin preparations.
Publications
Read Publication using
NBP1-42347 in the following applications:

  • 1 publication
  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Supernatant, 0.7% BSA
Preservative
0.1% Sodium Azide
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Purity
Tissue culture supernatant

Notes

The concentration of this material is approximately 0.25mg immunoglobulin/ml.

Alternate Names for MRP3 Antibody (M3II-9)

  • ABC31
  • ABCC3
  • ATP-binding cassette sub-family C member 3
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3
  • canalicular multispecific organic anion transporter 2
  • canicular multispecific organic anion transporter
  • CMOAT2
  • EC 3.6.3
  • EC 3.6.3.44
  • EC 6.3.2.4
  • EC 7.6.2.3
  • MLP2
  • MLP2DKFZp686E22157
  • MOAT-D
  • MRP3
  • MRP3MOAT-DEST90757
  • multidrug resistance associated protein
  • Multidrug resistance-associated protein 3
  • Multi-specific organic anion transporter D

Background

The protein encoded by the MRP3 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MRP3 Antibody (NBP1-42347)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC-P, WB.


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IHC-P
(1)
WB
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MRP3 Antibody (NBP1-42347) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ABCC3