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Mouse sP-Selectin/CD62P Quantikine ELISA Kit

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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse sP-Selectin/CD62P Quantikine ELISA Kit Summary

Background
The Quantikine Mouse soluble P-Selectin (sP-Selectin) Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse sP-Selectin levels in cell culture supernates, serum, and EDTA plasma. It contains NS0-expressed recombinant mouse sP-Selectin and antibodies raised against the recombinant factor. Results obtained for naturally occurring mouse sP-Selectin showed linear curves that were... parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural mouse sP-Selectin.
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Specificity
Natural and recombinant mouse sP-Selectin
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Selp

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MPS00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse sP-Selectin/CD62P Quantikine ELISA Kit

  • CD62P antigen
  • CD62P
  • FLJ45155
  • GMP140
  • GRMP
  • PADGEM
  • PADGEMantigen CD62)
  • PSEL
  • P-Selectin
  • selectin P (granule membrane protein 140kDa, antigen CD62)
  • SELP

Background

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for P-Selectin/CD62P (MPS00)(22)

We have publications tested in 3 confirmed species: Mouse, Rat, Transgenic Mouse.


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Mouse
(20)
Rat
(1)
Transgenic Mouse
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Showing Publications 1 - 10 of 22. Show All 22 Publications.
Publications using MPS00 Applications Species
Puspitasari, YM;Ministrini, S;Han, J;Karch, C;Prisco, F;Liberale, L;Bengs, S;Akhmedov, A;Montecucco, F;Beer, JH;Lüscher, TF;Bongiovanni, D;Camici, GG; Hutchinson-Gilford progeria syndrome mice display accelerated arterial thrombus formation and increased platelet reactivity Thrombosis research 2024-07-18 [PMID: 39032390] (Transgenic Mouse) Transgenic Mouse
VP Kumar, S Biswas, GP Holmes-Ham, M Sheleg, S Stone, B Legesse, R Ofir, SP Ghosh Pre-Administration of PLX-R18 Cells Protects Mice from Radiation-Induced Hematopoietic Failure and Lethality Genes, 2022-09-28;13(10):. 2022-09-28 [PMID: 36292639] (Mouse) Mouse
SF Zou, YH Peng, CM Zheng, YX Fei, SW Zhao, HP Sun, JF Yang Octreotide ameliorates hepatic ischemia-reperfusion injury through SNHG12/TAF15-mediated Sirt1 stabilization and YAP1 transcription Toxicology and Applied Pharmacology, 2022-03-18;442(0):115975. 2022-03-18 [PMID: 35307376] (Mouse) Mouse
S Thangaswam, CA Branch, K Ambadipudi, SA Acharya Quercetin Completely Ameliorates Hypoxia-Reoxygenation-Induced Pathophysiology Severity in NY1DD Transgenic Sickle Mice: Intrinsic Mild Steady State Pathophysiology of the Disease in NY1DD Is Also Reversed Biomolecules, 2021-10-06;11(10):. 2021-10-06 [PMID: 34680105] (Mouse) Mouse
J Venugopal, J Wang, J Mawri, C Guo, D Eitzman Interleukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease Haematologica, 2021-09-01;0(0):. 2021-09-01 [PMID: 32817286] (Mouse) Mouse
T Delvaeye, MAJ De Smet, S Verwaerde, E Decrock, A Czekaj, RE Vandenbrou, K Lemeire, A Gonçalves, W Declercq, P Vandenabee, DV Krysko, L Leybaert Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock Sci Rep, 2019-11-12;9(1):16623. 2019-11-12 [PMID: 31719598] (Mouse) Mouse
H Hayashi, D Cherpokova, K Martinod, T Witsch, SL Wong, M Gallant, SM Cifuni, LP Guarente, DD Wagner Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice PLoS ONE, 2017-12-13;12(12):e0188341. 2017-12-13 [PMID: 29236713] (Mouse) Mouse
Aurélien Quenault Molecular magnetic resonance imaging discloses endothelial activation after transient ischaemic attack Brain, 2016-11-08;140(0):146-157. 2016-11-08 [PMID: 28031221] (Mouse) Mouse
Farina F, Sancini G, Battaglia C, Tinaglia V, Mantecca P, Camatini M, Palestini P Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice. PLoS ONE, 2013-02-25;8(2):e56636. 2013-02-25 [PMID: 23451061] (Mouse) Mouse
Sio SW, Moochhala S, Lu J Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene. Am. J. Respir. Crit. Care Med., 2009-10-01;181(1):36-46. 2009-10-01 [PMID: 19797759] (Mouse) Mouse
Show All 22 Publications.

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Bioinformatics

Gene Symbol Selp