Mouse GM-CSF DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

Showing Publications 1 - 10 of 27. Show All 27 Publications. Collapse Publications.

Publications using DY415	Applications	Species
Palanki, R;Riley, JS;Bose, SK;Luks, V;Dave, A;Kus, N;White, BM;Ricciardi, AS;Swingle, KL;Xue, L;Sung, D;Thatte, AS;Safford, HC;Chaluvadi, VS;Carpenter, M;Han, EL;Maganti, R;Hamilton, AG;Mrksich, K;Billingsley, MB;Zoltick, PW;Alameh, MG;Weissman, D;Mitchell, MJ;Peranteau, WH; In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America 2024-08-06 [PMID: 39078677] (Transgenic Mouse)		Transgenic Mouse
Mills, KAM;Westermann, F;Espinosa, V;Rosiek, E;Desai, JV;Aufiero, MA;Guo, Y;Mitchell, KA;Tuzlak, S;De Feo, D;Lionakis, MS;Rivera, A;Becher, B;Hohl, TM; GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus bioRxiv : the preprint server for biology 2024-01-04 [PMID: 38260364] (Mouse)		Mouse
JT Clark, OE Weizman, DL Aldridge, LA Shallberg, J Eberhard, Z Lanzar, D Wasche, JD Huck, T Zhou, AM Ring, CA Hunter IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii Cell Reports, 2023-02-23;42(3):112147. 2023-02-23 [PMID: 36827187] (Mouse)		Mouse
MB Lutz, S Ali, C Audiger, SE Autenrieth, L Berod, V Bigley, L Cyran, M Dalod, J Dörrie, D Dudziak, G Flórez-Gra, L Giusiano, GJ Godoy, M Heuer, AB Krug, CHK Lehmann, CT Mayer, SH Naik, S Scheu, G Schreibelt, E Segura, K Seré, T Sparwasser, J Tel, H Xu, M Zenke Guidelines for mouse and human DC generation European Journal of Immunology, 2022-10-27;0(0):. 2022-10-27 [PMID: 36303448] (Mouse)		Mouse
SE Gilchrist, GM Pennelli, S Hafizi Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia Cells, 2021-11-24;10(12):. 2021-11-24 [PMID: 34943789] (Mouse)		Mouse
BY Lee, EKJ Hogg, CR Below, A Kononov, A Blanco-Gom, F Heider, J Xu, C Hutton, X Zhang, T Scheidt, K Beattie, A Lamarca, M McNamara, JW Valle, C Jørgensen Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis Nature Communications, 2021-12-17;12(1):7336. 2021-12-17 [PMID: 34921158] (Mouse)		Mouse
Z Tang, D Davidson, R Li, MC Zhong, J Qian, J Chen, A Veillette Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity Cell Reports, 2021-12-14;37(11):110111. 2021-12-14 [PMID: 34910922] (Mouse)		Mouse
EK Robinson, S Covarrubia, S Zhou, S Carpenter Generation and utilization of a HEK-293T murine GM-CSF expressing cell line PLoS ONE, 2021-04-09;16(4):e0249117. 2021-04-09 [PMID: 33836009] (Mouse)		Mouse
T Castro-Dop, A Fleming, TW Dennison, JR Ferdinand, K Harcourt, BJ Stewart, Z Cader, ZK Tuong, C Jing, LSC Lok, RJ Mathews, A Portet, A Kaser, S Clare, MR Clatworthy GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation Cell Rep, 2020-07-07;32(1):107857. 2020-07-07 [PMID: 32640223] (Mouse)		Mouse
M Costanza, PL Poliani, P Portararo, B Cappetti, S Musio, F Pagani, L Steinman, MP Colombo, R Pedotti, S Sangaletti DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation Proc. Natl. Acad. Sci. U.S.A., 2019-04-15;0(0):. 2019-04-15 [PMID: 30988194] (Mouse)		Mouse
S De Alessan, GJ Ferguson, AJ Dodd, JK Juss, A Devaprasad, S Piper, O Wyatt, H Killick, DJ Corkill, ES Cohen, A Pandit, TRDJ Radstake, R Simmonds, AM Condliffe, MA Sleeman, AS Cowburn, DK Finch, ER Chilvers Neutrophil GM-CSF receptor dynamics in acute lung injury J. Leukoc. Biol., 2019-04-03;0(0):. 2019-04-03 [PMID: 30942918] (Mouse)		Mouse
DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 2018-09-01;0(0):. 2018-09-01 [PMID: 29596569] (Mouse)		Mouse
L Serre, M Girard, A Ramadan, P Menut, N Rouquié, LE Lucca, K Mahiddine, B Leobon, LT Mars, S Guerder Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis J. Immunol., 2017-10-23;0(0):. 2017-10-23 [PMID: 29061767] (Mouse)		Mouse
S Musio, M Costanza, PL Poliani, E Fontana, M Cominelli, G Abolafio, L Steinman, R Pedotti Treatment with anti-Fc?RI? antibody exacerbates EAE and T-cell immunity against myelin Neurol Neuroimmunol Neuroinflamm, 2017-04-14;4(3):e342. 2017-04-14 [PMID: 28616446] (Mouse)		Mouse
VK Pulakazhi, A Adijiang, T Seibert, YX Chen, C Shi, Z Batulan, ER O'Brien Heat shock protein 27-derived atheroprotection involves reverse cholesterol transport that is dependent on GM-CSF to maintain ABCA1 and ABCG1 expression in ApoE(-/-) mice FASEB J, 2017-02-23;0(0):. 2017-02-23 [PMID: 28232480] (Mouse)		Mouse
Exon skipping of Fc?RI? eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy Proc. Natl. Acad. Sci. U.S.A., 2016-11-21;113(49):14115-14120. 2016-11-21 [PMID: 27872312] (Mouse)		Mouse
ER? in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity J Immunol, 2016-05-13;0(0):. 2016-05-13 [PMID: 27183630] (Mouse)		Mouse
K Klocke, S Sakaguchi, R Holmdahl, K Wing Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood Proc Natl Acad Sci USA, 2016-04-11;0(0):. 2016-04-11 [PMID: 27071130] (Mouse)		Mouse
Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Mucosal Immunol, 2014-12-10;8(4):896-905. 2014-12-10 [PMID: 25492474] (Mouse)		Mouse
Kim J, Li W, Choi Y, Lewin S, Verbeke C, Dranoff G, Mooney D Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy. Nat Biotechnol, 2014-12-08;33(1):64-72. 2014-12-08 [PMID: 25485616] (Mouse)		Mouse
Serezani CH, Kane S, Collins L Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis. J. Immunol., 2012-06-13;189(2):906-15. 2012-06-13 [PMID: 22696442] (Mouse)		Mouse
Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems. PLoS ONE, 2012-02-29;7(2):e32125. 2012-02-29 [PMID: 22393384] (Mouse)		Mouse
Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J. Immunol., 2011-12-23;188(3):1503-13. 2011-12-23 [PMID: 22198948] (Mouse)		Mouse
Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia. J. Immunol., 2011-10-14;187(10):5346-56. 2011-10-14 [PMID: 22003204] (Mouse)		Mouse
El-Behi M, Ciric B, Dai H The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol., 2011-04-24;12(6):568-75. 2011-04-24 [PMID: 21516111] (Mouse)		Mouse
Kim N, Saudemont A, Webb L, Camps M, Ruckle T, Hirsch E, Turner M, Colucci F The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion. Blood, 2007-07-20;110(9):3202-8. 2007-07-20 [PMID: 17644738] (Mouse)		Mouse
Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways. Biochem. Pharmacol., 2007-03-12;73(12):1957-70. 2007-03-12 [PMID: 17445776] (Mouse)		Mouse
Show All 27 Publications. Collapse Publications.

Array DY415

• GM-CSF Antibodies
• GM-CSF Antibody Pairs
• GM-CSF ELISA Kits
• GM-CSF Lysate
• GM-CSF Proteins
• GM-CSF ELISAs
• GM-CSF Proteins and Enzymes