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MMP-24/MT5-MMP Antibody

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Immunohistochemistry-Paraffin: MMP-24/MT5-MMP Antibody [NBP3-17274] - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: MMP-24/MT5-MMP Antibody [NBP3-17274] - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MMP-24/MT5-MMP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTK
Predicted Species
Mouse (96%), Rat (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MMP24
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for MMP-24/MT5-MMP Antibody

  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.80
  • matrix metallopeptidase 24 (membrane-inserted)
  • matrix metalloproteinase 24 (membrane-inserted)
  • matrix metalloproteinase-24
  • membrane-type 5 matrix metalloproteinase
  • Membrane-type matrix metalloproteinase 5
  • Membrane-type-5 matrix metalloproteinase
  • MMP24
  • MMP-24
  • MT5MMP
  • MT5-MMP
  • MT5-MMPMMP25
  • MT-MMP 5
  • MTMMP5
  • MT-MMP5

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MMP24