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MERIT40/HSPC142 Recombinant Protein Antigen

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications AC

Order Details

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MERIT40/HSPC142 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human MERIT40/HSPC142.

Source: E. coli

Amino Acid Sequence: SLPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFNLEGL

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
BABAM1
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-49568.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for MERIT40/HSPC142 Recombinant Protein Antigen

  • BABAM1
  • BRISC and BRCA1 A complex member 1
  • C10orf62
  • C19orf62
  • chromosome 19 open reading frame 62
  • FLJ20571
  • HSPC142
  • mediator of Rap80 interactions and targeting 40 kDa
  • Mediator of RAP80 interactions and targeting subunit of 40 kDa
  • MERIT40
  • MERIT40BRCA1-A complex subunit MERIT40
  • NBA1
  • NBA1BRISC and BRCA1 A complex member
  • new component of the BRCA1 A complex
  • New component of the BRCA1-A complex
  • new component of the BRCAA1 A complex

Background

HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRC

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for MERIT40/HSPC142 Recombinant Protein Antigen (NBP2-49568PEP) (0)

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FAQs for MERIT40/HSPC142 Recombinant Protein Antigen (NBP2-49568PEP) (0)

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Bioinformatics

Gene Symbol BABAM1