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Mammaglobin A Antibody (MGB/4056)

Images

 
Immunohistochemistry-Paraffin: Mammaglobin A Antibody (MGB/4056) [NBP3-07423] - Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin A Mouse Monoclonal Antibody (MGB/4056).
Immunohistochemistry-Paraffin: Mammaglobin A Antibody (MGB/4056) [NBP3-07423] - Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin A Mouse Monoclonal Antibody (MGB/4056).
Protein Array: Mammaglobin A Antibody (MGB/4056) [NBP3-07423] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Mammaglobin A Mouse Monoclonal Antibody (MGB/4056).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
MGB/4056
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

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Mammaglobin A Antibody (MGB/4056) Summary

Description
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08641)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
Immunogen
Recombinant full-length human Mammaglobin A protein (Uniprot: Q13296)
Localization
Cytoplasmic expression in ductal cells. Additional plasma positivity in lactating breast.
Marker
Breast Cancer Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SCGB2A2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2 ug/ml
  • Protein Array
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Theoretical MW
18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for Mammaglobin A Antibody (MGB/4056)

  • mammaglobin 1
  • mammaglobin A
  • Mammaglobin-1
  • MGB1mammaglobin-A
  • MGC71974
  • Secretoglobin family 2A member 2
  • secretoglobin, family 2A, member 2
  • UGB2mammaglobin-1

Background

Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SCGB2A2
Uniprot