Lumican Antibody

Images

 
Western Blot: Lumican Antibody [NBP1-87726] - Validation of extracellular matrix proteins differentially expressed in CNV patients. Representative Western blot images cropped from different gels with different exposure. ...read more
Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726] - Staining of human breast shows moderate to strong cytoplasmic positivity.
Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726] - Staining of human skin shows moderate to strong cytoplasmic positivity in dermal cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Lumican Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: DFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LUM
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot Reported in scientific literature (PMID 25961303)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Lumican Protein (NBP1-87726PEP)
Publications
Read Publications using
NBP1-87726 in the following applications:

  • 2 publications
  • WB
    3 publications

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 31582785). Rat (89%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Lumican Antibody

  • KSPG lumican
  • LDC
  • LUM
  • lumican proteoglycan
  • Lumican
  • SLRR2D
  • SLRR2DLDCKeratan sulfate proteoglycan lumican

Background

Lumican encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Lumican Antibody (NBP1-87726)(5)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol LUM