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Lgr5/GPR49 Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, PoSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-28904AF350
Alexa Fluor 405
NBP1-28904AF405
Alexa Fluor 488
NBP1-28904AF488
Alexa Fluor 532
NBP1-28904AF532
Alexa Fluor 594
NBP1-28904AF594
Alexa Fluor 647
NBP1-28904AF647
Alexa Fluor 700
NBP1-28904AF700
Alexa Fluor 750
NBP1-28904AF750
Allophycocyanin
NBP1-28904APC
Biotin
NBP1-28904B
CoraFluor 1
NBP1-28904CL1
DyLight 350
NBP1-28904UV
DyLight 405
NBP1-28904V
DyLight 488
NBP1-28904G
DyLight 550
NBP1-28904R
DyLight 594
NBP1-28904DL594
DyLight 650
NBP1-28904C
DyLight 680
NBP1-28904FR
DyLight 755
NBP1-28904IR
FITC
NBP1-28904F
HRP
NBP1-28904H
Janelia Fluor 525
NBP1-28904JF525
Janelia Fluor 646
NBP1-28904JF646
Janelia Fluor 669
NBP1-28904JF669
PE
NBP1-28904PE
PerCP
NBP1-28904PCP
Unconjugated
NBP1-28904
mFluor Violet 450 SE
NBP1-28904MFV450
mFluor Violet 500 SE
NBP1-28904MFV500
mFluor Violet 610 SE
NBP1-28904MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-28904
BSA Free
NBP1-28904SS
BSA Free
NBP1-28904
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Lgr5/GPR49 Antibody [Janelia Fluor® 549] Summary

Immunogen
Synthetic peptide made to an internal portion of the human GPR49/LGR5 protein (within residues 650-700). [Swiss-Prot: O75473]
Localization
Cell-membrane; Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LGR5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow (Intracellular)
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID:32016468).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lgr5/GPR49 Antibody [Janelia Fluor® 549]

  • FEX
  • G protein-coupled receptor 49
  • GPR49
  • GPR49G-protein coupled receptor HG38
  • GPR67
  • G-protein coupled receptor 49
  • G-protein coupled receptor 67
  • GRP49
  • HG38
  • leucine-rich repeat containing G protein-coupled receptor 5
  • leucine-rich repeat-containing G protein-coupled receptor 5
  • leucine-rich repeat-containing G-protein coupled receptor 5
  • Lgr5
  • MGC117008
  • orphan G protein-coupled receptor HG38

Background

Leucine-rich repeat-containing LGR5, also known as GPR49, is an Orphan-A G-protein coupled receptor with an unknown ligand. GPR49 is a stem cell marker of the intestinal epithelium and the hair follicule, and is often expressed in the brain, skeletal muscle, placenta, and spinal cord. Because LGR5 is typically found in mouse hair follicles it may potentially be used to regrow hair in mice. GPR49/LGR5 antibodies are useful tools for research on hair loss and hair follicule development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Lgr5/GPR49
Antibody [Janelia Flu ...
NBP1-28904JF549
Lgr5/GPR49 Antibody [Janelia Fluor® 549]
Species: Hu, Mu, Po
Applications: WB, Flow, ICC/IF, IHC

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Meeting Report: 2nd International Antibody Validation Meeting
Bio-Techne brands Novus Biologicals® and R&D Systems® were proud to support the 2nd International Antibody Validation Meeting held at Bath University, on the 15-16 September, 2016. Almost 100 participants from around the world, including funde...  Read full blog post.
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Bioinformatics

Gene Symbol LGR5