Langerin/CD207 Antibody (929F3.01) [Alexa Fluor® 546] Summary
Immunogen |
Langerin/CD207 was used as immunogen. |
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
CD207 |
Purity |
Ion exchange chromatography |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:10-1:1000
- Immunocytochemistry/ Immunofluorescence 1:10-1:2000
- Immunohistochemistry
|
Application Notes |
Permeabilization is recommended for flow cytometry. |
Packaging, Storage & Formulations
Storage |
Store at -20C in the dark. Avoid freeze-thaw cycles. |
Buffer |
PBS and 50% Glycerol |
Preservative |
No Preservative |
Purity |
Ion exchange chromatography |
Notes
This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.
This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.
Alternate Names for Langerin/CD207 Antibody (929F3.01) [Alexa Fluor® 546]
Background
Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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