Laminin alpha 2 Antibody (2D4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 applications: IF/IHC, Immunohistochemistry, Immunohistochemistry-Paraffin.

Showing Publications 1 - 7 of 7.

Publications using H00003908-M01	Applications	Species
Amani V, Riemondy KA, Fu R et al. Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas Acta Neuropathol Commun 2023-09-28 [PMID: 37770931] (Immunohistochemistry, Immunohistochemistry-Paraffin)	Immunohistochemistry, Immunohistochemistry-Paraffin
Graziella S, Regia L, Taciani M et al. A coordinated approach for the assessment of molecular subgroups in pediatric ependymomas using low-cost methods. J Mol Med (Berl). 2021-04-26 [PMID: 33903940]
Sasaki A, Hirato J, Hirose T et al. Review of ependymomas: assessment of consensus in pathological diagnosis and correlations with genetic profiles and outcome. Brain Tumor Pathol. 2019-03-30 [PMID: 30929114]
Araki A, Chocholous M, Gojo J et al. Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma. Acta Neuropathol Commun 2016-08-22 [PMID: 27550150]
Zakrzewska M, Fendler W, Zakrzewski K et al. Altered MicroRNA Expression Is Associated with Tumor Grade, Molecular Background and Outcome in Childhood Infratentorial Ependymoma. PLoS One 2016-07-08 [PMID: 27390862] (IF/IHC)	IF/IHC
Dong H, Ding H, Young K et al. Advanced Intimal Hyperplasia Without Luminal Narrowing of Leptomeningeal Arteries in CADASIL. Stroke. 2013-03-12 [PMID: 23482599]
Lemons JM, Feng XJ, Bennett BD et al. Quiescent fibroblasts exhibit high metabolic activity. PLoS Biol 2010-10-01 [PMID: 21049082]

Array H00003908-M01

• Laminin alpha 2 Antibodies
• Laminin alpha 2 Proteins