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Lamin A + C Antibody (4C4) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, ICC/IF
Clone
4C4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-25151AF350
Alexa Fluor 405
NBP2-25151AF405
Alexa Fluor 488
NBP2-25151AF488
Alexa Fluor 532
NBP2-25151AF532
Alexa Fluor 594
NBP2-25151AF594
Alexa Fluor 647
NBP2-25151AF647
Alexa Fluor 700
NBP2-25151AF700
Alexa Fluor 750
NBP2-25151AF750
Biotin
NBP2-25151B
CoraFluor 1
NBP2-25151CL1
DyLight 350
NBP2-25151UV
DyLight 405
NBP2-25151V
DyLight 550
NBP2-25151R
DyLight 594
NBP2-25151DL594
DyLight 650
NBP2-25151C
DyLight 680
NBP2-25151FR
DyLight 755
NBP2-25151IR
FITC
NBP2-25151F
HRP
NBP2-25151H
Janelia Fluor 525
NBP2-25151JF525
Janelia Fluor 549
NBP2-25151JF549
Janelia Fluor 585
NBP2-25151JF585
Janelia Fluor 635
NBP2-25151JF635
Janelia Fluor 646
NBP2-25151JF646
Janelia Fluor 669
NBP2-25151JF669
Unconjugated
NBP2-25151
mFluor Violet 450 SE
NBP2-25151MFV450
mFluor Violet 500 SE
NBP2-25151MFV500
mFluor Violet 610 SE
NBP2-25151MFV610
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Lamin A + C Antibody (4C4) [DyLight 488] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Full length recombinant human lamin A expressed in and purified from E. coli. [UniProt# P02545]
Localization
Nucleus. Nucleus envelope.
Marker
Nuclear Envelope Marker
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LMNA
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Monkey and Mouse reactivity reported in scientific literature (PMID:31871052).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Lamin A + C Antibody (4C4) [DyLight 488]

  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • dilated 1A (autosomal dominant)
  • EMD2
  • FPLD
  • HGPSFPL
  • lamin A/C
  • lamin A/C-like 1
  • lamin-A/C
  • LDP1
  • LFP
  • LGMD1B
  • limb girdle muscular dystrophy 1B (autosomal dominant)
  • LMN1IDC
  • LMNC
  • LMNL1
  • prelamin-A/C
  • PRO1,70 kDa lamin
  • progeria 1 (Hutchinson-Gilford type)
  • renal carcinoma antigen NY-REN-32

Background

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Lamin A + C
Antibody (4C4) [DyLig ...
NBP2-25151G
Lamin A + C Antibody (4C4) [DyLight 488]
Species: Hu, Mu, Rt, Pm
Applications: WB, ICC/IF

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol LMNA